最近收录_第798页_生物活性分子
生物活性分子最近更新
PIN1 Protects Hair Cells and Auditory HEI
Norbinaltorphimine dihydrochloride (Standard)
UCM
MCE
Salfredins, new aldose reductase inhibitors produced by Crucibulum sp. RF
Strain specificity of lactobacilli with promoted colonization by galactooligosaccharides administration in protecting intestinal barriers during Salmonella infection PMID 36894120
Neutrophil elastase inhibitor, sivelestat sodium hydrate prevents ischemia
Dec
feasible acceptor
Mannan
Knockdown of endogenous RNF4 exacerbates ischaemia
Daphnetin protects against cisplatin
Scheffoleoside A 160669
Inhibition of glycolysis by a novel EGFR/HER2 inhibitor KU004 suppresses the growth of HER2+ cancer PMID 28532652
Photochemical activation of TRPA1 channels in neurons and animals PMID 23396078
Discovery of Investigational Drug CT1812, an Antagonist of the Sigma
Photodynamic effect of deuteroporphyrin IX and hematoporphyrin derivatives on single neuron PMID 11243861
Metachromins X
A BACH1 inhibitor ameliorates myocardial infarction and limb ischemia in mice PMID 40676837
Azathioprine, 6
Lack of macrophage migration inhibitory factor regulation is linked to the increased chronotropic action of angiotensin II in SHR neurons PMID 17261648
Helicobacter pylori CagA protein induces gastric cancer stem cell
Identification of 2
Probing the folding pathways of four
IRG1 catalyzed energy metabolite itaconic acid restrains type I interferon
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition PMID 27376689
Corwin
Neuronal differentiation by indomethacin and IBMX inhibits proliferation of small cell lung cancer cells in vitro PMID 21511354
MKC
Synthesis and structure
Oleanane
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication PMID 36758070
Klebsiella pneumonia
Methocinnamox Reverses and Prevents Fentanyl
Effect of RGD
ML
Design and Synthesis of EZH2
Synthesis and biological evaluation of 3
Hirudonucleodisulfide A 1072789
Xirestomig 2756879
Discovery of a Small
Methyl lucidenate D 98665
Vasonatrin peptide attenuates myocardial ischemia
Ethaverine, a derivative of papaverine, inhibits cardiac L
KIRA8 attenuates non
10
Comparative review of the carbapenems PMID 17488146
MCE
Design, synthesis and biological evaluation of 7H
Novel strategies for PEDV to interfere with host antiviral immunity through Caspase
Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol
Treatment with Ibrutinib Inhibits BTK
Broad antiproliferative effects of benidipine on cultured human mesangial cells in cell cycle phases PMID 12381964
Sinococuline, a bioactive compound of Cocculus hirsutus has potent anti
Nylidrin hydrochloride 849
E1
Apigenin alleviates doxorubicin
Osivelotor 2417955
IDO5L 914471
Development and validation a LC
Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis PMID 31101821
MCE
MCE
Interleukin
Ibrolipim increases ABCA1/G1 expression by the LXRα signaling pathway in THP
Angiopep
L770644
RTS
Minimal Structural Variation of GPR84 Full Agonist Causes Functional Switch to Inverse Agonism PMID 40183744
Identification of 4
Designed multiple ligands for the treatment of type 2 diabetes mellitus and its complications Discovery of (5
Two
Anti
Electrode Based on the MWCNTs and Electropolymerized Thymolphthalein for the Voltammetric Determination of Total Isopropylmethylphenols in Spices PMID 36985043
Homocysteine Suppresses Autophagy Through AMPK
DcR3/TNFRSF6B 蛋白, Human (HEK293, His)
Biotin
acidic peptide
CST1 promotes the proliferation and migration of PDGF
Tauroursodeoxycholate
Isolation and structural characterisation of 8
LSD1
Vimentin binds to a novel tumor suppressor protein, GSPT1
FTY 720P
Molecular mapping of the binding site for a blocker of hyperpolarization
MPP7 promotes the migration and invasion of breast cancer cells via EGFR/AKT signaling PMID 33377561
MCE
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33
Reduced serotonin impairs long
Modified Peptide YY Molecule Attenuates the Activity of NPY/AgRP Neurons and Reduces Food Intake in Male Mice PMID 31074796
A new radioimmunoassay of thyrotropin
GGPS1 蛋白, Human (HEK293, His)
PCK1 inhibits cGAS
Bucloxic acid calcium 32808
Inhibition of two different cholinesterases by tacrine PMID 16860785
Aganirsen antisense oligonucleotide eye drops inhibit keratitis
Metabolic characteristics and antidepressant mechanism of cerebroprotein hydrolysate oral liquid via regulating tyrosine hydroxylase and neurotransmitter balance PMID 41475181
Targeted Modulation of FAK/PI3K/PDK1/AKT and FAK/p53 Pathways by Cucurbitacin B for the Antiproliferation Effect Against Human Cholangiocarcinoma Cells PMID 32907364
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease PMID 25611507
pyrimidone
Design, synthesis and biological evaluation of macrocyclic NTRK heterobifunctional degraders PMID 41483860
In vitro and in vivo effects of 3
Micrococcin P1 67401
Chronic morphine induces cyclic adenosine monophosphate formation and hyperpolarization
2
Acebutolol
Cytotoxic constituents from the rhizomes of Curcuma zedoaria PMID 25126594
1
Aldose reductase inhibitory constituents of the root of Salvia miltiorhiza Bunge PMID 9377780
Rhodanine derivative LJ001 inhibits TGEV and PDCoV replication in vitro PMID 32956749
Using tert
Ribavirin shows immunomodulatory effects on activated microglia PMID 25393884
G9a stimulates CRC growth by inducing p53 Lys373 dimethylation
Acid Red 94 sodium 632
Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine PMID 8103345
The mniopetals, new inhibitors of reverse transcriptases from a Mniopetalum species (Basidiomycetes). I. Producing organism, fermentation, isolation and biological activities PMID 7520899
PEDF
Antitumor Activity of Spicatoside A by Modulation of Autophagy and Apoptosis in Human Colorectal Cancer Cells PMID 27064730
阿糖腺苷(Standard)
Mal
SKF
Ebselen rescues oxidative
Antinociceptive and antineuropathic effects of cuminaldehyde, the major constituent of Cuminum cyminum seeds Possible mechanisms of action PMID 32222574
BD
MCE
Deoxythymidine
Paliroden 188396
The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08
GST
SDZ 208
Food additives Sodium benzoate, potassium sorbate, azorubine, and tartrazine modify the expression of NFκB, GADD45α, and MAPK8 genes PMID 28229641
3,5,7,3′,4′
MCE
BIX
SSTR3 Agonist
IHCH
Design and synthesis of novel chloramphenicol amine derivatives as potent aminopeptidase N (APN/CD13) inhibitors PMID 19423354
MCE
Discovery of a Partial Glucokinase Activator Clinical Candidate Diethyl ((3
α
Structure of the cytosine
Rspo1/Rspo3
A multifunctional oxidative stress amplifier for synergistic disruption of redox homeostasis and enhanced cancer therapy PMID 40902490
The mevalonate coordinates energy input and cell proliferation PMID 30975976
Discovery of a dual action first
SPARC a key mediator of apoptosis in human umbilical vein endothelial cells and its role in hypertension mechanism PMID 40229525
Sangivamycin, a nucleoside analogue, is a potent inhibitor of protein kinase C PMID 3338987
humanized IgG1
EAFGVNMQIVR 1072779
MAGL
Qualitative and quantitative dataset of TROL protein interaction with C3 and C4 ferredoxin NADP+ oxidoreductases PMID 31938718
UC
Mutant IDH1 inhibitor
Valproic acid exhibits different cell growth arrest effect in three HPV
Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3
Lixarkitug 3035710
Design, synthesis and pharmacological evaluation of N4,N6
UniPR500 2085767
The ribosome
Synthesis and biological evaluation of curcuminoid pyrazoles as new therapeutic agents in inflammatory bowel disease effect on matrix metalloproteinases PMID 19128977
Patchouli alcohol protects against myocardial ischaemia
[Phloretin induces apoptosis of BEL
Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells PMID 25242136
Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin
Antibacterial effect of amentoflavone and its synergistic effect with antibiotics PMID 23727809
Development, Optimization, and Structural Characterization of an Efficient Peptide
Flunixin 38677
Synthesis and discovery of triazolo
The function and allosteric control of the human sweet taste receptor PMID 32416872
ITF 3756 2247608
LY255582
[9
Structural characterization and immunomodulatory activity of a water
GADD45β
2
Neutrophil membrane
BI
Carnosol mitigates Ang II
ICI 118587
Identification of fenoldopam as a novel LSD1 inhibitor to abrogate the proliferation of renal cell carcinoma using drug repurposing strategy PMID 33349457
Erythropoietin and VEGF exhibit equal angiogenic potential PMID 12204656
HA1/Hemagglutinin 蛋白, H3N2 (AAA43178, HEK293, His)
Avpr2 Mouse Pre
Resorcinol
In vitro activity of a new semisynthetic echinocandin, LY
CGS15943
Mivelsiran sodium (ALN
Pharmacological Characteristics of Porcine Orexin 2 Receptor and Mutants PMID 32296386
Asic1 Rat Pre
Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction PMID 17897630
Rapid separation and identification of major constituents in Pseudolarix kaempferi by ultra
Effect of KT
Pharmacokinetic, metabolic stability, plasma protein binding and CYP450s inhibition/induction assessment studies of N
ALDH1A3, a metabolic target for cancer diagnosis and therapy PMID 26991532
CRBN ligand
[Research advance of functional plant pharmaceutical cycloartenol about pharmacological and physiological activity] PMID 28952245
RhoA 抗体 (YA093)（RhoA Antibody (YA093)）
Autophagy Induction by Trichodermic Acid Attenuates Endoplasmic Reticulum Stress
Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors A preliminary attempt to unravel the enigma of glioblastoma PMID 33744690
A synergistic
UCP1
Resmethrin 10453
ALK5
KRH
Synthalin A
Colesevelam suppresses hepatic glycogenolysis by TGR5
Thiacetazone (Thioacetazone，氨硫脲)
Discovery of LB30057, a benzamidrazone
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity PMID 29202016
HA1/Hemagglutinin 蛋白, H5N1 (ABJ96777, HEK293, His)
MCE
Fosl2
Potential of Polygonum cuspidatum Root as an Antidiabetic Food Dual High
Peptide YY (PYY) (3
L
Synthesis, biosimulation and pharmacological evaluation of benzimidazole derivatives with antihypertensive multitarget effect PMID 38977106
DMG
Supramolecular
Dietary L
Trimeric assembly and three
Systematic screening of excipients to stabilize aerosolized lipid nanoparticles for enhanced mRNA delivery PMID 40689160
Guaifenesin cyclic carbonate
1
Generic Hapten Synthesis, Broad
Resazurin sodium 62758
FadD32 Inhibitor
Expression and Hormonal Regulation of Entpd3 at Various Estrous Cycle Stages in the Mouse Uterus PMID 39567465
Mcl1
Anti
AMPK protects against alcohol
KuWal
Palmitoylation controls recycling in lysosomal sorting and trafficking PMID 18817523
Mefluleucine 2095886
HEYL Human Pre
Evaluation of an octahydroisochromene scaffold used as a novel SARS 3CL protease inhibitor PMID 31926775
Sodium diethylcarbamodithioate trihydrate 20624
FSHR
Design, synthesis, and biological activity evaluation of 2
HA/Hemagglutinin 蛋白, H1N1 (ABU99109, HEK293, His)
The Protective Effect of Aspirin Eugenol Ester on Oxidative Stress to PC12 Cells Stimulated with H2O2 through Regulating PI3K/Akt Signal Pathway PMID 34257805
Ex vivo effects of the dual topoisomerase inhibitor tafluposide (F 11782) on cells isolated from fresh tumor samples taken from patients with cancer PMID 12853890
Etomidate and other non
Novel 3
Puberulic acid
Cholic Acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6
Structure, molecular modeling, and function of the novel potassium channel blocker urotoxin isolated from the venom of the Australian scorpion Urodacus yaschenkoi PMID 24723491
Preclinical Development of the Anti
Hanlp24
Antiarthritic profile of BF
MCE
CDK9
2
(
RA16
Pleurotus ferulae water extract enhances the maturation and function of murine bone marrow
MCE
CDK2/4/6
Diisopropylamine
Urease, Jack bean
1
SMU
HA/Hemagglutinin 蛋白, H1N1 (ABD15258, HEK293, His)
Effect of doxazosin on cholesterol synthesis in cell culture PMID 2471008
Dyrk1A
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure
Equisetin as potential quorum sensing inhibitor of Pseudomonas aeruginosa PMID 29502217
MCE
Mcl
Azomethine
Matrix metalloproteinase (MMP)
Maribavir
Smart biomimetic metal organic frameworks based on ROS
CCI
FBL promotes hepatocellular carcinoma tumorigenesis and progression by recruiting YY1 to enhance CAD gene expression PMID 40289107
Elafin inhibits obesity, hyperglycemia, and liver steatosis in high
Brodimoprim effects of subminimal inhibitory concentrations on virulence traits of respiratory and urinary tract pathogens, and on plasmid transfer and stability PMID 8808712
Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells PMID 25596737
HIV
DMN
Synthetic Extracellular Matrix of Polyvinyl Alcohol Nanofibers for Three
Gastrodin relieved complete Freund's adjuvant
Factor B
Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4
Xalnesiran 2538784
Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation PMID 36978133
MCE
SSTR4 agonist 3 2744188
IDH889 1429179
Synthesis and biological evaluation of new series of quinazoline derivatives as EGFR/HER2 dual
l
Ildr2
INI
Boc
H
Fmoc
Boc
Gly
Z
Anti
Z
Z
Boc
Boc
His
Z
Phe
Z
Fmoc
Fmoc
Activation of GPER1 by G1 prevents PTSD
H
H
Fmoc
Boc
Z
Fmoc
GSK
H
H
Trt
H
H
MAO
Fmoc
Z
SARS
Boc
Structure
Z
Z
SIRT
Bafilomycin D 98813
Wnt5A modulates integrin expression in a receptor
Erectile dysfunction comparison of efficacy and side effects of the PDE
ABM125
RMG1
BM
Celangulin
CP
Respiratory pathogens
KH
FASN
AB
Indusatumab
USP20 Human Pre
Boc
2
Ogdhl Rat Pre
hsa
Novel class of thiourea compounds that inhibit herpes simplex virus type 1 DNA cleavage and encapsidation resistance maps to the UL6 gene PMID 10982350
Val
S14671
mDia1
LY221068 132392
Discovery of highly potent, selective, and brain
Disposition and Pharmacology of a GalNAc3
Fluorizoline
UNC0224
CSP 2503
3
2,3,4
Ioforminol 1095110
Edoxaban
KIR3DL1
PLS
Methyl 2
m
Ensaculin
HE 69
NPRL2 promotes TRIM16
HDAC1 activator
Morphology and volatile compounds of metathoracic scent gland in Tessaratoma papillosa (Drury) (Hemiptera Tessaratomidae) PMID 23950062
Levoglucosan
Comprehensive characterization of early
Hypoxia
PAB
Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables PMID 20551074
Acute Three
Mal
Collection and Identification of Allelopathic Compounds from the Undisturbed Root System of Bigalta Limpograss (Hemarthria altissima) PMID 16662150
The effects of SB 204070, a highly potent and selective 5
ML314 A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse PMID 27119457
RO5073012
Rolditamig
Paquinimod prevents development of diabetes in the non
IGF
HBV/HDV
The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats PMID 9806223
Cafestol, a coffee
胞外发育不良 A 受体（EDAR）基因
Dipeptidyl peptidase IV inhibitor MK
LSP1
Small molecule receptor agonists and antagonists of CCR3 provide insight into mechanisms of chemokine receptor activation PMID 17635911
TNF 受体超家族成员 13B（TNFRSF13B）基因
TMBIM1 promotes proliferation and attenuates apoptosis in glioblastoma cells by targeting the p38 MAPK signalling pathway PMID 35279540
Ring closure strategy leads to potent RIPK3 inhibitors PMID 33730678
Anti
Leptodactylone 61899
Chaperone
LSD1
α
LSD1
其他 (Other)
Reversible Ponceau staining as a loading control alternative to actin in Western blots PMID 20206115
Recombinant human interleukin
Leptodactylone
AP
KJ
Staphylococcus aureus ClpP
A Novel Inhibitor of Poly(ADP
3
CI
Nitroxazepine hydrochloride 16398
Metabotropic glutamate receptor (mGluR)
Halomicin, a new Micromonospora
IPM
Exploration of 6
钙/钙调蛋白依赖性蛋白激酶 ID（CAMK1D）基因
ABC44 1831135
Jacaric acid 28872
B32B3
JNK2 抗体 (YA326)（JNK2 Antibody (YA326)）
VH032
CRBN ligand
GSK3β
Antiviral agent 57 3027227
Fargesone B 116424
A 410099.1, amine
Study of novel selective mGlu2 agonist in the temporo
IITR08367
Bemfivastatin hemicalcium 805241
ZL1101
IKK
Functional diversity of SDF
D
2
Emavusertib phosphate 2376399
Characterization of vitamin B12 in Dunaliella salina PMID 26788012
H
Fosphenytoin reduces hippocampal neuronal damage in rat following transient global ischemia PMID 10398998
Meloxicam impurity 3 118854
Improvement of insulin sensitivity by a novel drug candidate, BGP
Boc
L
Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction PMID 30798137
D
Acefylline piperazine 18833
Effect of Bazi Bushen Capsule on D
Fmoc
MCE
EPH 受体 A10（EPHA10）基因
D5261
Pomalidomide
Ontogenetic differences in the effects of EEDQ on dopamine
AFD 21
Tet50
CP671305
5
YVPGP
Fmoc
H
3
N
SPB 858128
Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint PMID 30485802
PARP7
ARL6IP6
PI3Kα
Laevigatin A 122588
Discovery of (R)
Hydrazinocurcumin 131068
α
Inhibition of Integrin
N
Phytanoyl
BAY
Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate PMID 30261343
Fmoc
low hERG
Antifungal agent 74 2856379
Isopentenyl pyrophosphate triammonium 116057
Receptor tyrosine kinase signaling required for integrin alpha v beta 5
Design of novel and highly selective SARS
Fmoc
Fmoc
Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors PMID 31383629
Cantuzumab ravtansine 868747
SB
Poly(dA dT)
Aggregation
Biological activities of C
Methyl acetylacetate
STING agonist
Boc
ABAT 抗体 (YA1964)（ABAT Antibody (YA1964)）
One NY
1p
HIV
6,7,4'
共964页
首页
上一页
803
802
801
800
799
798
797
796
795
794
793
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新