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Autotaxin
Recilisib sodium 922139
SNAP
NI
SNAP 430
SDZ
蛋白磷酸酶 6 调节亚基 2（PPP6R2）基因
Dissociation of multiply charged negative ions for hirudin (54
Disperse Blue 106 68516
Chlorpromazine versus metiapine for schizophrenia PMID 28349512
Quinoline carboxylic acid derivatives as potent ectonucleotidase inhibitors PMID 41723137
CNN1 Human Pre
4
NI
Chloxyle
RELAX10
Metiapine
Aftin 4
Participation of transient receptor potential vanilloid 1 in the analgesic effect of duloxetine for paclitaxel induced peripheral neuropathic pain PMID 35149198
NBzF
SLF1 Human Pre
PROTAC EZH2 Degrader
8
Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity PMID 18558747
Amino
TP 0438836
MCE
APL
A synthetic inhibitor of histone deacetylase, MS
Gedatolisib 1197160
Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY
Efinaconazole 164650
Lysophosphatidic acid induces vasodilation mediated by LPA1 receptors, phospholipase C, and endothelial nitric oxide synthase PMID 24249637
CPD Human Pre
GPC5 Human Pre
Bay 41
Novaluron 116714
Ealamines A
The septin modifier, forchlorfenuron, activates NLRP3 via a potassium
Lurasidone metabolite 14283
Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers
Small
m
Selective mode of action of guanidine
1,4,7
MCE
phencyclidine site
Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension PMID 34669463
PARP1 抗体 (YA246)（PARP1 Antibody (YA246)）
The effect of desogestrel, gestodene, and other factors on spotting and bleeding PMID 8838484
Potentiators exert distinct effects on human, murine, and Xenopus CFTR PMID 27288484
Adjuvant 4
m6A Regulates Liver Metabolic Disorders and Hepatogenous Diabetes PMID 33160098
L
Structurally diversified ent
Slc11a2
RLY
Malate dehydrogenase a model for structure, evolution, and catalysis PMID 7849603
Serum pantetheinase/vanin levels regulate erythrocyte homeostasis and severity of malaria PMID 26343328
Metabolic Soft Spot and Pharmacokinetics Functionalization of C
CCOE
A small
PRPS2 蛋白, Human (His)
Nemoralisin 942480
sleep
NSC174055
(Rac)
An investigation into the structure
L
NCA
Methyldopate 6014
KMUP
NOD
Aaptamine Alters Vimentin Expression and Migration Capability of Triple
PDE8B
Phillyrin reduces ROS production to alleviate the progression of intervertebral disc degeneration by inhibiting NF
Bone
NK1971
Isoxazole
Dog colonoscopy model for predicting human colon absorption PMID 16783662
UBE2V2
AK
NH
Cucurbitacin
INU
Endomorphin 2 141801
NAI
Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors PMID 21187443
ER degrader 1 2667015
DL
Therapeutic Potential of Momordicine I from Momordica charantia Cardiovascular Benefits and Mechanisms PMID 39408847
tuberculosis
Discovery of PKMYT1 Inhibitors with a Novel Scaffold for the Treatment of Triple
hsa
Anti
Elucidating the Role of Wildtype and Variant FGFR2 Structural Dynamics in (Dys)Function and Disorder PMID 38674107
ATG12
Trimethoprim pentanoic acid
RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes PMID 33979620
Fmoc
VEGFR
TG 062
SM04554
AGN 192403 175521
NTPDase2
Kuromanin chloride 7084
Chek2
Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins PMID 8725399
Ferfluor1
Ferfluor
Nicotine dependence
YF
MCE
Fibrinogen exacerbates α
SG
PPm 2101951
Runx1
Intestinal microflora plays a crucial role in the genotoxicity of the cooked food mutagen 2
VAL 083
phospholipid peroxidation
BE
Q
SG62 250683
SG62
YF 438
Progranulin promotes proliferation, migration and invasion via the PI3K/Akt signalling pathway in a model of endometriosis PMID 36604215
Solid
COX
SG 62
YF438 2247210
Enrichment of Ly6Chi monocytes by multiple GM
Potential Antiphotoaging Effect of Human Cathelicidin LL
HSR 903
Remdesivir maleate 2250110
Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase? PMID 22438843
RapaLink
Syringaldazine 14414
ITPKA
Expression of Programmed Death Ligand 1 Is Associated with the Prognosis of Intrahepatic Cholangiocarcinoma PMID 31410753
Prioritization of Eleven
SV40 T
MCE
Xamoterol
Dulcoside C 64432
MCE
A unique beta1,3
MGA Human Pre
Effect of size and N
TRIM31 enhances chemoresistance in glioblastoma through activation of the PI3K/Akt signaling pathway PMID 32765650
Neojiangyouaconitine
Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing PMID 22289892
NitroSpeed
ClpP activator
Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation PMID 28467792
Structural Basis of the Diversity of Adrenergic Receptors PMID 31801060
Sesamol Epigenetically Induces Estrogen Receptor α Re
(4R,4S)
Etarfolatide 479578
Structures of new dammarane
NIBR0213 1233332
Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response PMID 14722642
Thalidomide
Benzenemethanamine,N
Prostaglandin F1a
EU 1622
Resveratrol
Transforms of Cell Surface Glycoproteins Charge Influences Tumor Cell Metastasis via Atypically Inhibiting Epithelial
Apelin
非洲芦荟提取物 (Aloe africana)
Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5
The S
Benzyl
MCE
RIFM fragrance ingredient safety assessment, hexyl hexanoate, CAS Registry Number 6378
Novel Glycoprotein VI Antagonists as Antithrombotics Synthesis, Biological Evaluation, and Molecular Modeling Studies on 2,3
A
MMV390048 1314883
Ametryn
DIM
NGB 2904 189060
Muscarinic M4 modulator
Tubulin/MMP
Spexin
H
N
Effects of MK
A synthetic farnesoid X receptor (FXR) agonist promotes cholesterol lowering in models of dyslipidemia PMID 19136377
Novel c
ABT
KRAS
ZD1839
Amb123203
DG 1
C8
Disitamab 2185868
Wittifuran X 1309478
Small
α
Levocarnitine propionate hydrochloride 119793
GM611
MA 2029
MARCKS
Fura
CRBN ligand
rel
t
11(Z)
GFB
RXDX
PROTAC Linker32
Inhibition of farnesyltransferase with A
proteolysis targeting molecule
Endokinin C 347837
AG
SRI
DOTAGA
MRS2693
A 3373
Kcnn4 Rat Pre
4
Cytotoxic prenylflavonoids from Artocarpus elasticus PMID 16309328
ANO1
PR
CDK8
ARN2966 102212
Spermidine
VX710
Aplysinopsin analogs Synthesis and anti
PF00477736
S
Sumatriptan
HC
Tyr
Vitamin C enhances the ex vivo proliferation of porcine muscle stem cells for cultured meat production PMID 35411884
A331440
Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling PMID 26919579
Effect of Sceptridium ternatum extract (STE) on radiation
MCE
Pharmacokinetic Comparison of 20(R)
Development of a CD8 co
Neoglucobrassicin 5187
Fluorimetric assay for D
Synthesis and Anti
KLF6
2
胰岛素样生长因子 1（IGF1）基因
SSBP2 Human Pre
ent
In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide PMID 7543976
Aloe capensis extract 100084
N
Neutrophil
(Rac)
20
阿帕鲁胺(Standard)
Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb PMID 19422820
The pharmacological activity of nicotine and nornicotine on nAChRs subtypes relevance to nicotine dependence and drug discovery PMID 17241116
GK241 1899930
Discovery of N
AQP9 causes recurrent spontaneous abortion by inhibiting trophoblast cell EMT and invasion through the PI3K/AKT pathway PMID 37602667
Monocyte chemoattractant protein
AG
ABT
Identification of (E)
The small
Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamics PMID 36880744
IL
14CO2
TPKI
UCM710
Potent antigen
MCE
HNRNPH2 Human Pre
BQQ
The molecular biology of meiosis in plants PMID 25494464
Olamufloxacin 167887
Macrocarpal H
Reconstructed Human Epidermis
Inhibition of T
Discovery and preclinical profile of LX
Bisquinolines. 1. N,N
New Substituted Cyanoindoline Derivatives as MAP3K14 Kinase Inhibitors for the Treatment of Cancer and Autoimmune Disorders PMID 28947934
Glyoxal
Infectious bronchitis virus (IBV) triggers autophagy to enhance viral replication by activating the VPS34 complex PMID 38574829
Neuronal D
Cy5.5 bis
Klf6 Rat Pre
microbial degradation
Itgae
Determination of urinary 13C
Evidence that TD
GM
Geraniol interferes with membrane functions in strains of Candida and Saccharomyces PMID 3050345
Indolin
MRLB
RGMc 抗体 (YA8879)（RGMc Antibody (YA8879)）
histone hyperacetylation
BRD4 Mediates Transforming Growth Factor
(11Z,13E)
Discovery of lipid
Intracellular pH measurements using flow cytometry with 1,4
Cloning, Expression, and Cost Effective Purification of Authentic Human Epidermal Growth Factor With High Activity PMID 27247796
Dihydroisotanshinone II (二氢异丹参酮II)
Long noncoding RNA AK144717 exacerbates pathological cardiac hypertrophy through modulating the cellular distribution of HMGB1 and subsequent DNA damage response PMID 39395058
Neu5Gcα(2
Neurochemical, Behavioral, and Neurogenic Validation of a Hyposerotonergic Animal Model by Voluntary Oral Consumption of para
18 1 PE (DOPE) pSar25 2936622
Recombinant human interleukin 5 is a selective activator of human eosinophil function PMID 2826636
Identification of pinostilbene as a major colonic metabolite of pterostilbene and its inhibitory effects on colon cancer cells PMID 26990242
Mechanism of L
C1QA 抗体 (YA1213)（C1QA Antibody (YA1213)）
SBF1 Human Pre
1,3,5
Novel potent blockers for TWIK
Succinic acid
Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models PMID 23700406
Pyralis farinalis
3,3'
Biflavones from Ginkgo biloba as inhibitors of human thrombin PMID 31446241
ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models PMID 33008036
Trinitrophenyl
Levocarnitine propionate
Large
LY836
Heptadecan
PDS
Identification of ABX
Protective effects of nicergoline against neuronal cell death induced by activated microglia and astrocytes PMID 16325157
Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu
Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation PMID 15001218
SP 141
Efficacy and tolerability of flexibly
ATX
JV
BAY678
TRIM60 Human Pre
PLGA/PEG
AIM 100
Macrophage metabolic reprogramming ameliorates diabetes
Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells PMID 27429805
Evaluation of rifalazil in long
Arbutin Inhibited Heat Stress
Ovaries
nitrite secretion
ITGAE Human Pre
Androgens
Competitive cAMP antagonists for cAMP
Melperone, an aytpical antipsychotic drug with clozapine
IL
Design, synthesis, and bioactivities of tasiamide B derivatives as cathepsin D inhibitors PMID 30734395
Effects of rehabilitation training on apoptosis of nerve cells and the recovery of neural and motor functions in rats with ischemic stroke through the PI3K/Akt and Nrf2/ARE signaling pathways PMID 28843352
Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats PMID 22610782
MT
Eperisone hydrochloride 56839
Zervimesine 1802632
SKF 83959 80751
R
SC
DNA Methyltransferase Inhibition Upregulates the Costimulatory Molecule ICAM
Effect of cyclamate sodium, saccharin sodium and stevioside on arginine
Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3 PMID 27009967
c
BMS
Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS
Ficolin A and ficolin B aggravate poly(I C) secondary LPS stimulation
17
HA1/Hemagglutinin 蛋白, H1N2 (ABQ42444, HEK293, His)
Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics PMID 19091563
CMPD101 hydrochloride 1941168
含 V 组结构域的 T 细胞激活抑制剂 1（VTCN1）基因
Basis of narrow
Biochemical and pathological studies on the effects of levamisole and chlorambucil on Ehrlich ascites carcinoma
Anticancer alkaloid lamellarins inhibit protein kinases PMID 19172192
Non
21
Astaxanthin suppresses LPS
Discovery of a potent and selective GPR120 agonist PMID 22519963
Inhibition of Voltage
Structural analyses define the molecular basis of clusterin chaperone function PMID 40781479
Discovery of a 3
A Covalent Calmodulin Inhibitor as a Tool to Study Cellular Mechanisms of K
Staphylococcus aureus Infection Induces the Production of the Neutrophil Chemoattractants CXCL1, CXCL2, CXCL3, CXCL5, CCL3, and CCL7 by Murine Osteoblasts PMID 36880752
Quercetin promotes angiogenesis and protects the blood
Selective Antitumor Effect and Lower Toxicity of Mitochondrion
The OsbHLH002/OsICE1
Vincamine 1617
Effect of the rho
New alkaloids of the sarpagine group from Rauvolfia serpentina hairy root culture PMID 12141861
N
Structurally optimized analogs of the retrograde trafficking inhibitor Retro
Mutagenicity of nitrofluoranthenes, 3
Phytantriol
Dehydroglyasperin C 199331
Neutrophil elastase inhibitor (sivelestat) may be a promising therapeutic option for management of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID
Targeted treatment of folate receptor
NMDAR antagonist 5 3038464
Recurrent moderate hypoglycemia accelerates the progression of Alzheimer's disease through impairment of the TRPC6/GLUT3 pathway PMID 35077394
1
CRBN ligand
Synthetic approaches, anticancer potential, HSP90 inhibition, multitarget evaluation, molecular modeling and apoptosis mechanistic study of thioquinazolinone skeleton Promising antibreast cancer agent PMID 32540783
DHFR
AFF1 Human Pre
GART promotes multiple myeloma malignancy via tumor stemness mediated by activating the HSP90α/CDK6/β
Fragment
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade PMID 30388455
MK0859
Identification of a Novel Cuproptosis
MCE
Fragment
PXR
N
Structure
Pregnenolone
TCO
Dioxoisoindolin
Inhibition of neutrophil elastase prevents cigarette smoke exposure
PLK4
VGF
H1.3 接头组蛋白，簇成员（H1
HO
Towards repositioning of quinacrine for treatment of acute myeloid leukemia
(S)
Macrophage migration inhibitory factor is released as a complex with alpha1
Plasma Erythropoietin, IL
GSK2041706A 1032824
Pridopidine 346688
Pyroptotic Macrophage
Composition dependence of vesicle morphology and mixing properties in a bacterial model membrane system PMID 16150420
Asperlin from the marine
(+)
Synthesis and biological evaluation of novel substituted pyrrolo[1,2
Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties PMID 41704373
8
BDNF 蛋白, Mouse (R129A, R130A, HEK293, C
Reaction of 2,6
CDK7 inhibitors as anticancer drugs PMID 32385714
(5Z,14Z)
Reduction of voluntary ethanol consumption in alcohol
Synthesis and Biological Evaluation of Benzocyclooctene
K6PC
Br
Insulin
Engineered synthetic cell penetrating peptide with intracellular anti
ALN
Fenvalerate
Cysteamine an old drug with new potential PMID 23416144
Lipid A
Nonapeptide
reprimo，TP53 依赖性 G2 停滞调解员同系物（RPRM）基因
白细胞介素 13（Il13）基因
A novel, broad
BRD4 degrader
Design, synthesis, and X
Ssrp1 Mouse Pre
Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti
A small
层粘连蛋白亚基β1（LAMB1）基因
p
Asp
MCE
Thorough QT/QTc in a Dish An In Vitro Human Model That Accurately Predicts Clinical Concentration
Ethyl (4
Lemnalol Modulates the Electrophysiological Characteristics and Calcium Homeostasis of Atrial Myocytes PMID 31671563
Hydroxylation and hydrolysis two main metabolic ways of spiramycin I in anaerobic digestion PMID 24345568
Melengestrol acetate and megestrol acetate are prostatic tumor inhibiting agents PMID 2268413
Myogenin suppresses apoptosis induced by angiotensin II in human induced pluripotent stem cell
Antiplatelet activity of loureirin A by attenuating Akt phosphorylation In vitro studies PMID 25445049
The Methylcitrate Cycle is Required for Development and Virulence in the Rice Blast Fungus Pyricularia oryzae PMID 30933666
Phytochemicals, antioxidant, antinociceptive and anti
CaMKIIα
Acid
LSD1
2
Discovery of 2
An anti
E3 ligase Ligand 49 1911013
Fmoc
含 THAP 域 7（THAP7）基因
Alleviating CB2
Activation of the aryl hydrocarbon receptor is essential for mediating the anti
Pharmacological actions of a novel, potent, tissue
前列腺素 F2 受体抑制因子（PTGFRN）基因
Glucagon receptor antagonist
PC
Homoharringtonine synergizes with quizartinib in FLT3
Dissimilar influences of imipramine, benactyzine and promazine on effects of micro
Dissecting caspase
N,N'
3
溶质载体家族 12 成员 5（SLC12A5）基因
Boc
CBP/p300
Inhibition of Toll
生长抑素受体 1（Sstr1）基因
PLLA10000
ABT
H
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