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BAY
N
C6
MCE
UUO model
ACTH (3
MCE
NSC
ATP
S
VEGFD
CD2
CG
Safety, tolerability, and pharmacokinetics of amuvatinib from three phase 1 clinical studies in healthy volunteers PMID 22349808
Cannabiphorol
CRBN ligand
NS1652 1566
ZIF
Contribution of serotonin (5
Second generation of alpha
MKP10241 2137977
MF 438
NSC
Antiproliferative activity of diarylheptanoids from the seeds of Alpinia blepharocalyx PMID 11379774
Neuroprotective kappa
NVS
Intepirdine 607742
Fluorescence derivatization
Inhibition of endoplasmic reticulum associated degradation reduces endoplasmic reticulum stress and alters lysosomal morphology and distribution PMID 23515578
Thalidomide
Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma
Perakine
SUCNR1 Deficiency Alleviates Liver Ischemia
Structure
GSK217
FGF 401
Biochemical characterization of dihydroorotase of Leishmania donovani Understanding pyrimidine metabolism through its inhibition PMID 27650727
CNDAC hydrochloride 134665
TAK 044 157380
Synthesis and cytotoxic activity of 5,6
BRD4
UR
CRBN ligand
JNJ
Discovery and mechanism of action studies of 4,6
Structure
Linoleoyl LPA
Elatoside F 144118
Antiplasmodial effect of benzimidazole
Differential processing of stromal
Serum taurine affects lung cancer progression by regulating tumor immune escape mediated by the immune microenvironment PMID 39243941
LKB1/ STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms PMID 33579786
Lysine hydroxamate 25125
GPNMB and ATP6V1A interact to mediate microglia phagocytosis of multiple types of pathological particles PMID 39992792
Cross
Itaconate
The molecular mechanism underlying mitophagy
MCE
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling PMID 11074000
NE
cis
Hepatoprotective role of vardenafil against experimentally induced hepatitis in mice PMID 27762466
Characteristics of the ambulation
CTR2
SLC25A3
HA/Hemagglutinin 蛋白, H1N1 (AFR76227, HEK293, His)
Quantitative phosphoproteomic analysis reveals chemoresistance
Insulin Receptor Beta 抗体 (YA5878)（Insulin Receptor Beta Antibody (YA5878)）
Luotonin F 244616
AC
Conserved properties of individual Ca2+
USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer PMID 38233848
Pomalidomide
Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides PMID 17696514
Poliumoside
Dimeric 1,4
AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto
Tetrastigma hemsleyanum Diels et Gilg polysaccharide mitigates macrophage pyroptosis and prevents acute lung injury by regulating NLRP3/Caspase
minerals
Antitumor Activity of the IGF
MCE
APD 334
Exametazime 105613
DX
Poloxamer 123 (L43) (PEG
Isolation, Identification, and Synthesis of a New Prenylated Cinnamic Acid Derivative from Brazilian Green Propolis and Simultaneous Quantification of Bioactive Components by LC
Abcd1
A human monoclonal antibody blocking SARS
Betacellulin 蛋白, Human (HEK293)
N
Hepatic noradrenergic innervation acts via CREB/CRTC2 to activate gluconeogenesis during cold PMID 38878857
Design, synthesis, molecular docking and anticancer activity evaluation of methyl salicylate based thiazoles as PTP1B inhibitors PMID 39929933
Aquaporin 2 抗体 (YA2142)（Aquaporin 2 Antibody (YA2142)）
Gal
mTOR
Calcitonin Gene
Recql4 Rat Pre
CSF1R
1,4
Benzylamide antagonists of protease activated receptor 2 with anti
Diquafosol Sodium Inhibits Apoptosis and Inflammation of Corneal Epithelial Cells Via Activation of Erk1/2 and RSK In Vitro and In Vivo Dry Eye Model PMID 30372737
Terodiline. A review of its pharmacological properties, and therapeutic use in the treatment of urinary incontinence PMID 2292235
BP766
Structure
phalloidin
SLC9A1 Human Pre
HSD17B13
Ganglioside GM1 Alleviates Propofol
First total synthesis of protoapigenone and its analogues as potent cytotoxic agents PMID 17622129
Arzoxifene, a new selective estrogen receptor modulator for chemoprevention of experimental breast cancer PMID 11731420
Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia PMID 29643228
Aldose reductase
Loss of Pip4k2c confers liver
Flupirtine enhances the anti
KRP297
Antibacterial agent 292 3065015
Identification of chikusetsusaponin IVa as a novel lysine
Antibiotics from Aspergillus melleus PMID 15405793
Septamycin 54927
EGFR
Cyclodrine hydrochloride 78853
Synthesis and antiviral properties of novel indole
S1PR1 agonist 3 3028594
Pyrroloquinolinone
Thymidine kinase 1/TK1 蛋白, Canine (His)
Glucose metabolism activation by SHIP2 inhibitors via up
Econazole a review of its antifungal activity and therapeutic efficacy PMID 98315
Formulation development and rheological studies of palatable cefetamet pivoxil hydrochloride dry powder suspension PMID 22615648
Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling PMID 28754668
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination PMID 30250201
The trapping of uridine phosphates by D
FGF19
Agonism and allosterism the pharmacology of the free fatty acid receptors FFA2 and FFA3 PMID 19719777
Desoxypeganine hydrochloride 61939
Efficacy and Safety of Berberine Alone for Several Metabolic Disorders A Systematic Review and Meta
MCE
LAS
H1
JSD
MCE
2
Simurosertib 1330782
S9490
Discovery of 5
Resorcinol monoethyl ether
The human IL
Coenzyme A sodium 55672
NSC
Danshenol A inhibits TNF
trans
AP
GPR120 Agonist 3 1599477
DLG
Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action PMID 31918015
Benzo[b]thiophene
GD3 ganglioside and apoptosis PMID 12531552
Azo
LY2365109 868265
Design, synthesis and cytotoxicity of bengamide analogues and their epimers PMID 30108762
MolPort
Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo PMID 24690777
Antibacterial activity of cuminaldehyde on food
H
Piperazinotriazole
Karanjin counteracts OVX
PR8
Cinnamamide derivatives with 4
MCE
Ceramide synthesis regulates T cell activity and GVHD development PMID 28515365
Self
Inflammatory cytokine production in tumor cells upon chemotherapy drug exposure or upon selection for drug resistance PMID 28915246
Indoleamine 2,3
Sequence
SARS
The role of 5
(S)
Platelet aggregation inhibitors. 2. Inhibition of platelet aggregation by 5'
PAR2 Modulators Derived from GB88 PMID 27994760
Theaflavin protects against oxalate calcium
A novel podophyllotoxin
Inhibition of the classical and lectin pathway of the complement system by recombinant LAIR
HBV
Chloride efflux in cyclic AMP
Eicosapentaenoic Acid 10417
Social defeat stress enhances the rewarding effects of cocaine through α1A adrenoceptors in the medial prefrontal cortex of mice PMID 37839511
VEGF receptor
7′,8′
DS
KAT2A/B
MBM
Electrospun emodin polyvinylpyrrolidone blended nanofibrous membrane a novel medicated biomaterial for drug delivery and accelerated wound healing PMID 22875606
Schinlignan B 77881
Nbr1
The long non
Pingyangmycin and Bleomycin Share the Same Cytotoxicity Pathway PMID 27376254
Molnupiravir combined with different repurposed drugs further inhibits SARS
M2 macrophage derived HMOX1 defines chronic rhinosinusitis with nasal polyps PMID 39644500
Subacute toxicity of anilofos, a new organophosphorus herbicide, in male rats effect on some physical attributes and acetylcholinesterase activity PMID 11906102
Toloxatone 29218
6'
Antiviral and cellular metabolism interactions between Dexelvucitabine and lamivudine PMID 17403996
MCE
DDR1 ligand 1
Yuanhuanin 83133
Lapemelanotide zapixetan
Metronidazole aryloxy, carboxy and azole derivatives Synthesis, anti
MCE
N6
Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape PMID 34767457
MLS000544460 352336
Synthesis and Characterization of Dendrimer
Pristimerin ameliorates colitis‑induced intestinal mucosal injury by inhibiting intestinal epithelial necroptosis PMID 40211716
AV 153
Combination of bexarotene and the retinoid CD1530 reduces murine oral
MCE
Fosfluridine tidoxil 174638
FYN is required for ARHGEF16 to promote proliferation and migration in colon cancer cells PMID 32811808
MK2 Phosphorylates RIPK1 to Prevent TNF
MCE
MCE
2'
DMPG (L
Rolditamig (TQB2102 Antibody)
EM
Synthesis and anti
Raddeanin A Protects the BRB Through Inhibiting Inflammation and Apoptosis in the Retina of Alzheimer's Disease PMID 38834846
WQ3810 (KPI
Lerimazoline
S
Farnesiferol A (法尼斯淝醇A)
Polyacrylate sodium
SCH 430765
Terbucarb
6
Discovery and Development of LX7101, a Dual LIM
Dynamic modeling of human 5
Skewing effect of sulprostone on dendritic cell maturation compared with dinoprostone PMID 29754770
Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A
Tau
RPR 102341
Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC) PMID 31710489
Dalchini extract
HIV
Tracazolate (ICI 136753)
IPA
HA/Hemagglutinin 蛋白, H1N1 (AKM14547, HEK293, His)
WCK
Induction of colonies of hemoglobin
Piquindone (Ro 22
Cyclin G2 promotes the formation of smooth muscle cells derived foam cells in atherosclerosis via PP2A/NF
Extracellular and intracellular zilpaterol and clenbuterol quantification in Hep G2 liver cells by UPLC
ITGB7
Preskimmianin 38695
Hesperidin Methylchalcone Suppresses Experimental Gout Arthritis in Mice by Inhibiting NF
Interaction of metargidin (ADAM
Treatment with nitric oxide donors diminishes hyperinfection by Strongyloides venezuelensis in mice treated with dexamethasone PMID 26342794
Identification of pyrrolo[3',4' 3,4]cyclohepta[1,2
MCE
Tssk2
Inhibitors of the Bub1 spindle assembly checkpoint kinase synthesis of BAY
AFB1 exacerbates testicular and intestinal inflammation by increasing stearoyl ethanolamide and homocysteine levels PMID 40424650
PEX19 抗体 (YA2888)（PEX19 Antibody (YA2888)）
TNFSF15
Deulorlatinib 2131126
Mucin
Anti
Lamivudine
TGFβ1 induces resistance of human lung myofibroblasts to cell death via down
MCE
Scoulerine promotes cytotoxicity and attenuates stemness in ovarian cancer by targeting PI3K/AKT/mTOR axis PMID 37708956
H
Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins PMID 8098709
Characteristics of repaglinide and its mechanism of action on insulin secretion in patients with newly diagnosed type
Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model PMID 38955905
HA1/Hemagglutinin 蛋白, H1N1 (ACP41934, HEK293, His)
Antimalarial agent 8 2715222
Endothelin ETB receptor is involved in sex differences in the development of balloon injury
Fzr regulates silk gland growth by promoting endoreplication and protein synthesis in the silkworm PMID 36652497
Design, synthesis and bioactivity evaluation of cinnamic acid derivatives as potential anti
Investigation of the mechanism of Isobavachalcone in treating rheumatoid arthritis through a combination strategy of network pharmacology and experimental verification PMID 35525528
Egg Yolk Phosphatidylethanolamine Extraction Optimization, Antioxidative Activity, and Molecular Structure Profiling PMID 30977912
Trpv5
Livagen
Boc
MCE
Structure
DPC083
A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL
Cholyl
GPER agonist G
NPS 2390 226878
NADPH oxidase modifies patterns of MHC class II
Boeravinone F
A highly sensitive electrochemical aptasensor for detection of microcystin
CARS2 Human Pre
New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone
oJak
IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies PMID 30455381
Boronic Acid A Novel Pharmacophore Targeting Src Homology 2 (SH2) Domain of STAT3 PMID 36170649
Identification of select glucocorticoids as Smoothened agonists potential utility for regenerative medicine PMID 20439738
CPP2 1313390
Design, synthesis and biological activity of a novel Rutin analogue with improved lipid soluble properties PMID 25496805
Paeonol protects against acute pancreatitis by inhibiting M1 macrophage polarization via the NLRP3 inflammasomes pathway PMID 35182973
COOH
Clinical and Preclinical Single
Paris saponin VII reverses chemoresistance in breast MCF
L
Design, synthesis and biological evaluation of novel HDAC inhibitors with improved pharmacokinetic profile in breast cancer PMID 32791401
Basigin/CD147 蛋白, Mouse (304a.a, HEK293, His)
NBzF
H3 成簇组蛋白 3（H3C3）基因
2
Preparation of S14161 and its analogues and the discovery of 6
Basil oil
LSD1
Voreloxin (Standard) (白血病孤儿药 (标准品))
ClpP agonist 1
WK500B
Knockdown of TRIM27 expression suppresses the dysfunction of mesangial cells in lupus nephritis by FoxO1 pathway PMID 30648253
Ricefidase (KJ
Leptodactylone (细指蟾酮)
(4S)
Amplification of snap
Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC) PMID 2779359
A dual
Epithelial HIF2α expression induces intestinal barrier dysfunction and exacerbation of arthritis PMID 35710307
Inhibition of cellular transformation by triphenylmethane a novel chemopreventive agent PMID 1638675
Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[ c][1,2,5]oxadiazole Derivatives as Potent PD
Aflatoxin B1 and Aflatoxin M1 Induce Compromised Intestinal Integrity through Clathrin
MCE
Cancer stem cell
Piezo1 participates in sevoflurane
PD
Golotimod TFA 2828433
HMN
H446
Antileishmanial agent
Skullcapflavone I 41060
Comparison of the grignard deacylation TLC and HPLC methods and high resolution 13C
Liver
TGA
SMC6 Human Pre
Metabolic activation of pradefovir by CYP3A4 and its potential as an inhibitor or inducer PMID 16940083
Function
PACAP 1
TDAG8 activation attenuates cerebral ischaemia
Acute renal injury induced by valacyclovir hydrochloride A case report PMID 28101180
Camk1d
Protease Inhibitor VR23 Alleviates Severe Acute Pancreatitis with High Trypsin Synthesis in Mice PMID 40455346
vaginosis
DMT
Novel in vivo active anti
2'
Ahnak
Plasmacytoid dendritic cell
Dragendorff's reagent Historical perspectives and current status of a versatile reagent introduced over 150 years ago at the University of Dorpat, Tartu, Estonia PMID 32635970
Pharmacological properties of J
(±)
Imidacloprid induces abnormal glucose metabolism through NF
Rubiasin A 305819
HER1/EGFR
Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex
SGK1 inhibits oxidative injury and extracellular matrix degradation by activating the GSK
Tnfsf12
Design, synthesis and biological evaluation of 2
Artemisinin G (青蒿素G)
CRBN ligand
PFPeS
Initial Experience with Topical Fluorouracil for Treatment of HIV
Harnessing allostery a novel approach to drug discovery PMID 24827416
MRS4620 2411665
Cinnamomum zeylanicum extract
Mytoxin B and Myrothecine A Induce Apoptosis in Human Hepatocarcinoma Cell Line SMMC
The relaxant effects of cromakalim (BRL 34915) on human isolated airway smooth muscle PMID 1436131
9
Ras
白三烯 A4 水解酶
3'
Exploring the potential mechanisms of Jinglinzi powder in treating hepatocellular carcinoma based on LC
SelSA 1225038
Antibacterial effects of Traditional Chinese Medicine monomers against Streptococcus pneumoniae via inhibiting pneumococcal histidine kinase (VicK) PMID 26042111
AC
Discovery of CBPD
Azide
Vanillic acid attenuates Aβ1
Induction of thymocyte apoptosis by Ca2+
S63845 1799633
CRBN ligand
Azathioprine old drug, new actions PMID 12697731
MCE
细胞周期蛋白依赖性激酶 1（Cdk1）基因
Carmichasine B
Population pharmacokinetics of mavacoxib in osteoarthritic dogs PMID 21219337
A potent cyclic peptide targeting SPSB2 protein as a potential anti
Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice PMID 15319416
Palmaturbine
Neocaesalpin L (新云实苦素 L)
Asenapine citrate 1411867
Dihydroajugapitin
MCE
Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 pathway PMID 29725013
MPT0B390 1817802
2,4
Tolerability in man following inhalation dosing of the selective TLR7 agonist, AZD8848 PMID 26933507
Fondaparinux sodium 114870
(2S,3R)
(
Erratum Telocinobufagin inhibits the epithelial
The drug
A norovirus protease structure provides insights into active and substrate binding site integrity PMID 16227288
Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism PMID 26946249
The arginase inhibitor Nω
Mcl1
Difludiazepam 39080
Methyl P
1
Mitochondrial Metabolism
Design and synthesis of a tetrahydroisoquinoline
Analogs of MK
Dehydrogriseofulvin 3573
BIMAX1 1105053
Mauritianin 109008
Dopamine D1 receptor involvement in the discriminative
Comparative epileptogenic properties of two monobactam derivatives in C57, Swiss and DBA/2 mice PMID 8889722
Screening of inhibitors against histone demethylation jumonji domain
Indatuximab ravtansine (BT062) combination treatment in multiple myeloma pre
Endocrine properties of the testosterone 5 alpha
Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap PMID 39375448
Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase PMID 31153805
Activated TREM1
Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine PMID 8632334
Beacon[47
(3R,6S)
Evidence for Glucagon Secretion and Function Within the Human Gut PMID 33534908
Structural insights into Cn
The development and performance of a radioimmunoassay for the analysis of ZM 213,689, the major metabolite of meropenem
Genotoxicity assessment of the antiepileptic drug AMP397, an Ames
4'
Colorimetric ferrozine
Low
Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes PMID 19104661
Novel Azepinoindole Compounds as 5‑HT2A Agonists for Treating Neuropsychiatric and Neurodegenerative Disorders PMID 41256984
含 Tudor 域 3（TDRD3）基因
Phenanthrenes from Juncus articulatus with Antibacterial and Biofilm Formation Inhibitory Activity PMID 39121346
Bisphenol AF Halogen bonding effect is a major driving force for the dual ERα
Deruxtecan
Jacaric acid and its octadecatrienoic acid geoisomers induce apoptosis selectively in cancerous human prostate cells a mechanistic and 3
TA
TNX
FUS
SLAMF7
Characterization of novel MPS1 inhibitors with preclinical anticancer activity PMID 23933817
TGFBR1
Polymeric nanovesicles as simultaneous delivery platforms with doxorubicin conjugation and elacridar encapsulation for enhanced treatment of multidrug
Induction of cytotoxicity, aldehydic DNA lesions, and poly(ADP
Biosynthesis of eoxin C4 by porcine leukocytes PMID 22921794
Tnfrsf9
Anti
Cancer Cachexia in STK11/LKB1
Roxadustat ameliorates vascular calcification in CKD rats by regulating HIF
A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi
GALA 107658
Dihydrolipoic Acid 462
Chicken ovomucoid determination of its amino acid sequence, determination of the trypsin reactive site, and preparation of all three of its domains PMID 3548816
Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target PMID 16161998
Quantitation of trans
The farnesyltransferase inhibitor, FTI
HA/Hemagglutinin 蛋白, H1N1 (ABI19015, HEK293, His)
Thalidomide
Angiotensin I/II (1
A review of alternatives to di (2
MCE
Quality of life, safety and efficacy profile of thermostable flolan in pulmonary arterial hypertension PMID 25793960
New amidine
tert
1,3
Atractylodinol prevents pulmonary fibrosis through inhibiting TGF
Structural insights into how GlcNAc
Effect of carbendazim and pencycuron on soil bacterial community PMID 19616894
Identification of the first inhibitor of the GBP1 PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells PMID 25211704
AH 8532 786581
Pore
MR 409 1445155
Discovery of JNJ
Leucine aminopeptidases diversity in structure and function PMID 17132098
RET
Vitexin B
Elvucitabine
MC
N
Reversal of Epigenetic Peroxisome Proliferator
cis
Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF
Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability PMID 20571075
Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1
XH
Advanced glycation end
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