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TGF
Zorevunersen 2415330
LL37 complexed to double
Clerodane Diterpenoids Isolated from the Leaves of Casearia graveolens PMID 31916761
GRL
DDB1 抗体 (YA5274)（DDB1 Antibody (YA5274)）
Cytotoxic and antiplasmodial xanthones from Pentadesma butyracea PMID 19296616
Study of the Active Components and Molecular Mechanism of Tripterygium wilfordii in the Treatment of Diabetic Nephropathy PMID 34164430
The JNK inhibitor D
Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1
Use of substitute Nonidet P
Feasibility and efficacy of arginine 2
m
N
CD73 promotes tumor growth and metastasis PMID 22720214
Antitumor agent
Vitamin C
Synthesis and antitumor activity of cyclopentane
Protective Effects of Dihydrocaffeic Acid, a Coffee Component Metabolite, on a Focal Cerebral Ischemia Rat Model PMID 26133759
Functional regionalization of the differentiating cerebellar Purkinje cell population occurs in an activity
Pharmacological investigations on possible role of Src kinases in neuroprotective mechanism of ischemic postconditioning in mice PMID 24397498
Melanocortin receptor agonists MCR1
Pharmacology of LY195115, a potent, orally active cardiotonic with a long duration of action PMID 2438505
Development of novel urea
Macrophage Fcgamma receptors expression is altered by treatment with dopaminergic drugs PMID 10075867
Vitexins, nature
Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species. Structure
Ingitamig 2839572
Structure
MCE
BCR
MCE
Peroxynitrite
Setrusumab 1847394
Neuropsychiatric Comorbidity as Causal Influence in Autism PMID 31344460
Effects of sun drying combined with baking processes on the flavor quality of Chongqing Tuocha raw tea PMID 41285060
506U78
A new type of Ca
Activase
Novel 3,4
Combination of Ruthenium Complex and Doxorubicin Synergistically Inhibits Cancer Cell Growth by Down
Unveiling the chemistry of antibody conjugation for enhanced PET imaging Current trends and future directions PMID 39756200
MK
Elafin (elastase
BCN
SHR
Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase
pATG13
LAMC1 attenuates neuronal apoptosis via FAK/PI3K/AKT signaling pathway after subarachnoid hemorrhage PMID 38609046
DPP1 Inhibitor
Rebaudioside A directly stimulates insulin secretion from pancreatic beta cells a glucose
S1pr2
Lycopodine triggers apoptosis by modulating 5
7
Design, synthesis, and docking studies of quinazoline analogues bearing aryl semicarbazone scaffolds as potent EGFR inhibitors PMID 28428040
Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay PMID 26812546
hpol κ
Rational optimization of D3R/GSK
Cationic Nanoparticles Assembled from Natural
ICAM5
ZLM 66
PF07202954
MCE
Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance PMID 17167487
Dielectric blood coagulometry as a means of evaluating the change in thrombin generation induced by direct oral anticoagulants PMID 33217621
L
Bromochlorophenol Blue sodium salt 102185
hsa
allergic responses
Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds PMID 10658588
CDK9 inhibitor FIT
STh 118447
GPER1
1,1'
tert
Mechanisms governing target search and binding dynamics of hypoxia
UCB9608 1616413
MCE
ZWZH
pyroGlu
Noncanonical protease
Ntn1 Rat Pre
MCE
Ortho
broad
Discovery of Novel and Potent Dual PARP1/ERK Inhibitors as a Promising Strategy for Cancer Therapy PMID 41739621
DB
HY
LMD584
U92032
8
S1153
RARalpha antagonist Ro 41
Thalidomide
Cepharanthine mitigates NIBV
RPN13
TMP
LY 3361237
LO
BChE
HbF inducer2
FG 8205
Bianthrone
Peginterferon Beta
Gemilukast 1232861
IACS
AT
Synthetic and structure
PD142893
Caerulein, desulfated 20994
Thevebioside 114586
Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations PMID 28541286
CaMKII
Histone H4 peptide 852904
Atavaquone
Nocardicyclin B 199173
YI5301
Fradafiban 148396
Structure
Anticancer agent 16 2761205
Structure
AZT
Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease PMID 26477507
C
RX
Murralongin 53011
Fingolimod impurity 3 162358
Boc
Control of protein phosphorylation with a genetically encoded photocaged amino acid PMID 17965709
Tacapenem 193811
Loss of bhlha9 Impairs Thermotaxis and Formalin
Structure
ZL0580
Procaspase
JPS035 2669785
LMD
Increased translation driven by non
HT1080 cell
LARP4 Human Pre
CGP52608
Denecimig 2488745
ISIS
METTL3
STF083010
Development of activity
Protective Effects of 4
Nepetin limits NLRP3 inflammasome activation and alleviates NLRP3
ST13 1013620
SB
VUF11211 906556
Sirtuin modulator 4 327104
RP14539
memory T
YLF
Identification of Hck inhibitors as hits for the development of antileukemia and anti
(2S)
Discovery of novel aniline
Tacstd2
PF
Endochin 354155
MCE
HTLA cells
AS2863619
Analysis of the potential biological mechanisms of geniposide on renal fibrosis by network pharmacology and experimental verification PMID 39871379
Cycloviracin B1 142382
SEC inhibitor KL
dTDP disodium
Selective small molecule inhibitors of glycogen synthase kinase
MP
FLAG peptide 98849
Anthracimycin 1452849
BI 186908 1453500
Agnoside
Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore
Stathmin 1 抗体 (YA5629)（Stathmin 1 Antibody (YA5629)）
FT011 1001288
CR
REGN5678
(Rac)
In vitro antiinflammatory effects of neolignan woorenosides from the rhizomes of Coptis japonica PMID 11000020
MS 153
Q 203
Implications of Fagopyrin Formation In Vitro by UV Spectroscopic Analysis PMID 33916126
Atropine methyl bromide 2870
PSMA
Evaluation of 24 CYP2D6 Variants on the Metabolism of Nebivolol In Vitro PMID 27538917
CK571
Direct Blue108
Cell assay for the identification of amyloid inhibitors in systemic AA amyloidosis PMID 30739503
Ifnl2
Anti
VRR1
IL
Vorolanib
5
NSC698600
IDO1
Yogurt Prevents Colitis
AVN 211
PPD 10558
Galanin inhibits performance on rodent memory tasks PMID 9928180
KUR 1246
G631
pGlu
AG636
Identification of Chemotype Agonists for Human Resolvin D1 Receptor DRV1 with Pro
CD28
Enhancement of Ndrg2 promotes hypertrophic scar fibrosis by regulating PI3K/AKT signaling pathway PMID 39956247
Triptolide enhances lipolysis of adipocytes by enhancing ATGL transcription via upregulation of p53 PMID 32614500
Ac
Potent, Selective, and Drug
Dendronobiloside D 526222
SU5201 114727
DPC 963 214287
Thioredoxin
Bipoladien A, a Sesterterpenoid Containing an Undescribed 5/8/5/7 Carbon Skeleton from Bipolaris maydis PMID 38325810
Differential regulation of osteoclastogenesis by Notch2/Delta
TPKI
2,3
FLT3
HKI
Erbicin
MAP3K14
CGP52411 (Standard)
Macrocarpal H
Multimodular Optimization of Chemically Regulated T Cell Switches Demonstrates Flexible and Interchangeable Nature of Immune Cell Signaling Domains PMID 34662227
Inhibition of monoamine oxidase by 3,4
AgrC
Mitiperstat 1933460
Coffea robusta extract
Pristimerin enhances the effect of cisplatin by inhibiting the miR‑23a/Akt/GSK3β signaling pathway and suppressing autophagy in lung cancer cells PMID 30664149
tert
Pirenzepine 28797
Dual kinase
Novel Dibenzoazepine
Elafin prevents lipopolysaccharide
A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance PMID 33495648
Anti
Tridodecylmethylammonium chloride 7173
Spatiotemporal Circadian Oscillator Manipulation for Enhanced Ovarian Cancer Therapy Using a Versatile Nanoplatform PMID 40488667
30 0 Coenzyme A
Antitumoral Potential of the Histone Demethylase Inhibitor GSK
Homoharringtonine, an approved anti
Enhanced angiogenesis by the hyaluronic acid hydrogels immobilized with a VEGF mimetic peptide in a traumatic brain injury model in rats PMID 31827886
Tenilapine 82650
Network context and selection in the evolution to enzyme specificity PMID 22936779
TNFSF15
Small Fluorogenic Amino Acids for Peptide
PdCl2(Amphos)2 887919
AMPD2 inhibitor 1 (Standard)
1,3,5
Mechanism of Error
CWHM
Small
Thalidomide the tragedy of birth defects and the effective treatment of disease PMID 21507989
Vascular Endothelial Growth Factor Mimetic Peptide and Parathyroid Hormone (1
KLTWQELYQLKYKGI 917760
Deoxyshikonin inhibited rotavirus replication by regulating autophagy and oxidative stress through Sirt1/FoxO1/Rab7 axis PMID 36907361
Elezanumab, a human anti
Curcumin and treatment of melanoma The potential role of microRNAs PMID 28167449
Activation of proteinase
AICAR treatment for 14 days normalizes obesity
Acetyl
1
Discovery of Orally Bioavailable Selective Inhibitors of the Sodium
Ivermectin A Promising Therapeutic for Fighting Malaria. Current Status and Perspective PMID 34242031
Modification of HER2 pre
Nuclear genome
AMPA receptor antagonist
Formation of guanidinosuccinic acid, a stable nitric oxide mimic, from argininosuccinic acid and nitric oxide
Anti
Citric acid
PAM 1392 (2,4
Neuropeptide Y potentiates selectively the N
AChE/BuChE/MAO
p
chromanones
RAD21 Human Pre
Protective effects of the NLRP3 inflammasome against infectious bursal disease virus replication in DF
Two new prenylated 3
Anti
ICOS
JNJ
Effect of the motilin agonist KC 11458 on gastric emptying in diabetic gastroparesis PMID 15274670
Pharmacological mechanisms of action of flupirtine a novel, centrally acting, nonopioid analgesic evaluated by its discriminative effects in the rat PMID 2901483
MRT68921 hydrochloride 2070014
L 694746 139934
The Paf1 complex transcriptionally regulates the mitochondrial
Fused
Synthesis and application of an azobenzene amino acid as a light
Auramine
Synthesis and biological evaluation of the Fluoro analog of Romidepsin with improved selectivity for class I histone deacetylases (HDACs) PMID 40090152
TRIM21 modulates stability of pro
Momordicine I alleviates isoproterenol
multineurotarget agents
Mc
In vitro and in vivo activities of HPi1, a selective antimicrobial against Helicobacter pylori PMID 24687512
Synthesis and structure
CFTR inhibitors for treating diarrheal disease PMID 22850599
antimyeloma
p62
Characterization of ABT
Inhibition of hypoxia inducible factor
Usp3
UCM710
Nmb
含 C 型凝集素结构域 7A（CLEC7A）基因
Prolyl hydroxylase 2 deficiency limits proliferation of vascular smooth muscle cells by hypoxia
Ggt5
1,4
Lamin B2 抗体 (YA4174)（Lamin B2 Antibody (YA4174)）
Rafutrombopag diolamine 1257792
Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA
Dimethyloxallyl glycine/nanosilicates
Biochanin a ameliorates DSS
Knockdown of Golgi phosphoprotein 73 blocks the trafficking of matrix metalloproteinase
Sodium ionophore III (Standard)
Tris(4,7
Fluorescent labeling of chromosomal DNA superiority of quinacrine mustard to quinacrine PMID 5479635
Rps15 Rat Pre
2,3
Biochemical and biological properties of 4
t
Development of the First
The single
Design, synthesis and in vitro and in vivo biological evaluation of matrine derivatives as efficient anticancer agents with the characteristics of endoplasmic reticulum stress induction and apoptosis activation PMID 40273706
Substituted aminopyridines as potent and selective phosphodiesterase
cis
Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia PMID 34376782
MF5137
Selective up
Phenindione
Discovery of dermorphin
revertant
3
Metformin Alleviates Delayed Hydrocephalus after Intraventricular Hemorrhage by Inhibiting Inflammation and Fibrosis PMID 35852765
Cycloartenol exerts anti
DOPG 62700
Calenduloside F
Decreased chromate uptake in Pseudomonas fluorescens carrying a chromate resistance plasmid PMID 3112130
Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage
LGALS3 Human Pre
EDTA iron
Design, synthesis, biochemical evaluation, radiolabeling and in vivo imaging with high affinity class
OVA (329
Modulation of nuclear factor
LY280748 153226
Design and Discovery of α
FKBP14
Sarcandrolide D 1207185
SMD
Hyp
Mapk14 Mouse Pre
LASSBio2382
Justiciresinol 136051
Y
IBI344
GCN2
CRBN ligand
Sofosbuvir impurity 5 874638
Mild and ultrafast GLORI enables absolute quantification of m6A methylome from low
Biotin
Identification of 2
Tilsotolimod an investigational synthetic toll
4
q
Hybrids of selective COX
Microglial Cytokines Induce Invasiveness and Proliferation of Human Glioblastoma through Pyk2 and FAK Activation PMID 34944779
Pold2
The role of endothelin
EGFR
GW
HCV
Chimeras.
Design, synthesis and discovery of andrographolide derivatives against Zika virus infection PMID 31838328
mCMQ069 3025257
Epopromycin B 153540
The tumor
FTBMT, a Novel and Selective GPR52 Agonist, Demonstrates Antipsychotic
Inhibition of xanthine oxidase by phytic acid and its antioxidative action PMID 14738912
APOL1 抗体 (YA1893)（APOL1 Antibody (YA1893)）
Chiglitazar (Standard)
Identification of a Membrane Binding Peptide in the Envelope Protein of MHV Coronavirus PMID 32971895
Bioactive fraction from Plumeria obtusa L. attenuates LPS
Inhibition of chikusetsusaponin IVa on inflammatory responses in RAW264.7 cell line via MAPK pathway PMID 32986614
Antibiotics from basidiomycetes. XLI. Clavicoronic acid, a novel inhibitor of reverse transcriptases from Clavicorona pyxidata (Pers. ex Fr.) Doty PMID 1372310
Insulinotropic effect of Chikusetsu saponin IVa in diabetic rats and pancreatic β
LY3295668 erbumine (AK
HEC1B
Anti
Antithrombotic effect of chikusetsusaponin IVa isolated from Ilex paraguariensis (Maté) PMID 23134458
Mca
The enzymatic activities of CD38 enhance CLL growth and trafficking implications for therapeutic targeting PMID 24990614
Generation of functional human pancreatic β cells in vitro PMID 25303535
Stabilizing a Tubulysin Antibody
RSVA405 (Standard)
Presenilin 1 (349
Nonneurotoxic tetralin and indan analogues of 3,4
Ethalfluralin (丁氟消草)
Desamino lenalidomide
Bet1 Rat Pre
BV02 (Standard)
simplex
metabolic dysfunction
Design, synthesis, and biological evaluation of a series of 2
Estrogen receptor
Proteasome 20S alpha 2/HC3 抗体 (YA2384)（Proteasome 20S alpha 2/HC3 Antibody (YA2384)）
Lhx9
(R)
GHRH antagonists support lung endothelial barrier function PMID 31578921
MCE
Reboxetine
Phosphorylation of Akt by SC79 Prevents Iron Accumulation and Ameliorates Early Brain Injury in a Model of Experimental Subarachnoid Hemorrhage PMID 26978329
Novel small molecule inhibitors of TLR7 and TLR9 mechanism of action and efficacy in vivo PMID 24342772
HY
Ladostigil a novel multimodal neuroprotective drug with cholinesterase and brain
Hypertension Induces Cognitive Impairment and Alterations of Acetylcholine Receptor mRNA Expression in the Hippocampus and Cortex of Mice PMID 40947477
Design, Synthesis, and Bioevaluation of a Novel Hybrid Molecular Pyrrolobenzodiazepine
Simulated microgravity
Cuminaldehyde Aldose Reductase and alpha
A novel selective melanocortin
Mil
Pancreastatin (swine) 106477
Purification of creatine kinase
Menin
Enhanced delivery of camptothecin to colorectal carcinoma using a tumor
Development and validation of an UPLC
Discovery of novel small molecules targeting the USP21/JAK2/STAT3 axis for the treatment of triple
BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl
A novel SERS
RNA
FR234938 256461
1,3
Novel aminothiazoximone
Stereoselectivity and stereospecificity of the alpha,beta
Discovery of first
Detection of Sialic Acids on the Cell Surface Using Flow Cytometry PMID 36175624
Expression of interleukin
apoptotic effects
MYB41, MYB107, and MYC2 promote ABA
Structure of PDE3A
5
A selective androgen receptor modulator with minimal prostate hypertrophic activity restores lean body mass in aged orchidectomized male rats PMID 18502117
H
Identification of a compound that directly stimulates phospholipase C activity PMID 12695532
Amino acid modified xanthone derivatives novel, highly promising membrane
(+)
Daphnicyclidins A
PI4KIII beta inhibitor 4 3029505
Fusarubin 1702
Menin 蛋白, Human
Identification of a brain
Improved extraction and complete mass spectral characterization of steroidal alkaloids from Veratrum californicum PMID 24079166
MCE
Synthesis and in vivo evaluation of [11C]SN003 as a PET ligand for CRF1 receptors PMID 16529935
Intestinal HIF
Thioxothiazolidin derivative, 4
Msrb3 Rat Pre
Three ent
Bispiperidin
The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity PMID 34582681
Expression dynamics of periodic transcripts during cancer cell cycle progression and their correlation with anticancer drug sensitivity PMID 36529792
Surface immobilization of a protease through an inhibitor
Isocudraniaxanthone A 197447
SB
Relationship between the pyroptosis of fibroblast‑like synoviocytes and HMGB1 secretion in knee osteoarthritis PMID 33300062
Pharmacokinetics and pharmacodynamics of idrapril in rats, dogs, and humans PMID 7902245
Sarpogrelate 125926
MCE
The impact of JNK inhibitor D
CDK11 regulates pre
L
PD
Cefalexin hydrate (Standard)
Regio
4
In situ therapeutic vaccines for leukemia by chemo
MCE
(+)
GNE
NKp30/NCR3 蛋白, Human (HEK293, Fc)
MCE
[Effect of 1
Tri(Amino
Cefpodoxime sodium (R 3763 sodium，头孢泊肟钠盐)
Benzyl 4
Receptor density influences the recruitment bias of aripiprazole and brexpiprazole at the dopamine D2L receptor PMID 35767599
Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target PMID 34315984
Vigabatrin increases human brain homocarnosine and improves seizure control PMID 9851440
CP
Topoisomerase inhibitor 3 3026832
AMPK Activation Enhances Neutrophil's Fungicidal Activity in Vitro and Improves the Clinical Outcome of Fusarium solani Keratitis in Vivo PMID 35575029
Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation relevance in drug design PMID 17683281
腺苷脱氨酶（ADA）基因
hADSCs
Fmoc
ATTO 488 923585
Disulfiram inhibits epithelial
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