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Valsa mali
LIK066
FGFR
2',7
A71915
REA 抗体 (YA1848)(REA Antibody (YA1848))
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation PMID 31913317
NP
JZP
(R,R)
thyroid
cramps
Ceramide
TAK079
KL 373
PAX6 抗体 (YA3536)(PAX6 Antibody (YA3536))
ZnPcPs
AHSA1
Katacalcin
Aminooxy
TRC210258 1431553
DPP
Benzobicyclon 156963
Verubecestat TFA 2095432
Tolprocarb
ATPase
KF14124
gelation
SKF82526
H N.M.R. study of the conformation of [Glu4] oxytocin and its lanthanide complexes in aqueous solution PMID 7228492
Dihydroartemisinin inhibits the growth and invasion of gastric cancer cells by regulating cyclin D1
Octahydroisoindole
Ifidancitinib
HTL 22562
MCC 134
Ordastobart
T
SBE 13
BT
Blixeprodil 2881017
A novel NLRP3 inhibitor as a therapeutic agent against monosodium urate
Rapamycin analog
Discovery and characterization of NVP
(S,R,S)
PLK1
(7Z,10Z)
Case Study of Small Molecules As Antimalarials 2
mRNA
The E3 ligase TRIM21 promotes progression of pancreatic ductal adenocarcinoma by down
Targeting FGFR4 Abrogates HNF1A
TGIC (Standard)
2
Morin 3
MCE
4'
Design, Synthesis, and Evaluation of New Sugar
Reducing degradation of azo dye by zero
MCE
Synthesis and biological evaluation of new MET inhibitors with 1,6
Relationship between Menthiafolic Acid and Wine Lactone in Wine PMID 26321591
Screening of Poria cocos polysaccharide with immunomodulatory activity and its activation effects on TLR4/MD2/NF
Cysteine
Single
Structural basis for dual
(S)
Renal denervation attenuates cardiac dysfunction in HFpEF by inhibiting the ATP
hsa
Senaparib as first
Maleate trihydrate sodium 3105
CRBN ligand
Phospho
Metal Contamination of Oman Sea Seaweed and Its Associated Public Health Risks PMID 34415496
A Lysosome
5
Baohuoside
Fenspiride
Optovin 348575
MCE
Ratiometric Fluorescent Probe for Imaging of Pantetheinase in Living Cells PMID 28911222
Design, Synthesis, and Antitumor Evaluation of 4
A prohormone convertase cleavage site within a predicted alpha
A new target for growth hormone releasing
VAV2 抗体 (YA3312)(VAV2 Antibody (YA3312))
High fat diet
Posttranslational protein modifications as gatekeepers of cancer immunogenicity PMID 38747288
MCE
Anti
Cyclooxygenase
Toxicopathologic and pharmacologic properties of piperacetazine, a potent tranquilizing agent PMID 13999315
A novel palmitic acid hydroxy stearic acid (5
Tonabersat, a gap
Effects of efonidipine, an L
Desamino lenalidomide
Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck PMID 10213503
Prolonged adenosine A1 receptor activation in hypoxia and pial vessel disruption focal cortical ischemia facilitates clathrin
Structure
睾丸相关肌动蛋白重塑激酶 2(TESK2)基因
C‑X‑C receptor 7 agonist acts as a C‑X‑C motif chemokine ligand 12 inhibitor to ameliorate osteoclastogenesis and bone resorption PMID 35014674
Population pharmacokinetic analysis of dutogliptin, a selective dipeptidyl peptidase
D609 inhibits progression of preexisting atheroma and promotes lesion stability in apolipoprotein e
Experimental and Theoretical Studies on Iron
p31
Structural optimization and biological evaluation of 5
Exploring a potential palonosetron allosteric binding site in the 5
Ultrasonic complexation with Lycium barbarum polysaccharide significantly enhances the aqueous solubility and bioavailability of curcumin PMID 41223460
The C
甘露糖苷酶 alpha 2B 类成员 2(MAN2B2)基因
Potent and selective small
MCE
(R)
MCE
mPEG
Synthesis, isolation, stereostructure and cytotoxicity of paclitaxel analogs from cephalomannine PMID 23876369
Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis PMID 25404585
Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger
Modulation of circadian glucocorticoid oscillation via adrenal opioid
RO
Discovery and Characterization of Novel Receptor
Dual CDK4/CDK6 inhibition induces cell
Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4 PMID 17881493
Geranylgeraniol Inhibits Lipopolysaccharide
双苯二甲胺生物合成 2(DPH2)基因
Novel alpha
EDA
The Deficiency of SCARB2/LIMP
Induction and maintenance of mammary growth and lactation in rats with acetylcholine or epinephrine PMID 13645707
Impact of composition manipulation on lean lamb production in the United States PMID 8567487
hsa
Simultaneous LC
MCE
Inhibitory phenolic amides on lipopolysaccharide
New indole amide derivatives as potent CRTH2 receptor antagonists PMID 21515053
A Phase 2 clinical trial of PF
Potent Antitumor Activities and Structure Basis of the Chiral β
Metabolomic signatures in lipid
Synthesis, anti
Selective targeting of non
New estrogen receptor antagonists. 3,20
GPER agonist G
Advancing Immunotherapeutic Vaccine Strategies Against Pulmonary Tuberculosis PMID 33013927
Induction of rat pancreatic B
CD58 分子(CD58)基因
Amentoflavone inhibits the induction of nitric oxide synthase by inhibiting NF
Design of an Oral STING Agonist through Intramolecular Hydrogen Bond Ring Mimicking to Achieve Complete Tumor Regression PMID 40442142
Insulin
WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB
LL
白细胞介素 36 β(IL36B)基因
Nikkomycin Lx 242149
Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonists PMID 34713378
[Biological properties of 1,2
Plumericin Protects against Experimental Inflammatory Bowel Disease by Restoring Intestinal Barrier Function and Reducing Apoptosis PMID 33445622
NK
Trimetazidine attenuates dexamethasone
Glutaminolysis is required in maintaining immune regulatory functions in B cells PMID 35013572
Amentoflavone Induces Apoptosis and Inhibits NF
Reduction of experimentally produced acute myocardial infarction size by a new synthetic inhibitor, NCO
Tiotropium and Fluticasone Inhibit Rhinovirus
Unfolded Protein Response in Cancer IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability PMID 25589933
Baicalein Protects Against Aspergillus fumigatus Keratitis by Reducing Fungal Load and Inhibiting TSLP
4'
Antagonism of peptidoleukotrienes and inhibition of systemic anaphylaxis by RG 12525 in guinea pigs PMID 2539543
KLF15 negatively regulates cardiac fibrosis by which SDF
GABAB receptors regulate the neural stem cell potential of Pkd2l1+ cerebrospinal fluid
Heterologous Expression of Fluostatin Gene Cluster Leads to a Bioactive Heterodimer PMID 26465097
Isolation and Determination of Fomentariol Novel Potential Antidiabetic Drug from Fungal Material PMID 29675285
Strategies to reduce HERG K+ channel blockade. Exploring heteroaromaticity and rigidity in novel pyridine analogues of dofetilide PMID 23473309
真核翻译起始因子 2 α 激酶 1(EIF2AK1)基因
MCE
Rpgrip1l
AR ligand
In vivo activation of the p53 pathway by small
RhoA vesicle trafficking
Selective Inhibition of PTP1B by New Anthraquinone Glycosides from Knoxia valerianoides PMID 36399709
Identification of plumericin as a potent new inhibitor of the NF
Cycloastragenol targets Fpr2 to inhibit the TLR4/NF
Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats PMID 8282823
Preclinical evaluation of (177)lu
Biodegradation of bispyribac sodium by a novel bacterial consortium BDAM Optimization of degradation conditions using response surface methodology PMID 29438823
BICD 货物适配器 2(BICD2)基因
Effects of 6
Sonic hedgehog signaling regulates reciprocal epithelial
5α
Reversal of heparin
GSK3 alpha 抗体 (YA4055)(GSK3 alpha Antibody (YA4055))
Role of DAB2IP in modulating epithelial
In vitro and in vivo metabolic tagging and modulation of platelets PMID 40236816
New bisabolane
Identification of 6
Exo1 a new chemical inhibitor of the exocytic pathway PMID 12738886
Novel bifluorescent Zn(II)
MCE
霍乱弧菌感染 (Vibrio Cholerae Infection)
激活转录因子 1(ATF1)基因
MCE
ION582
Multifunctional roles of human cathelicidin (LL
SKI
6
Tnfsf10
N
NLS
Diazaquinomycins E
HIV
DBCO
ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors identification, in vitro pharmacology, pharmacokinetic and biodistribution studies PMID 17110115
Novel alpha
Design, Synthesis, and Biological Evaluation of Isoform
Amentoflavone alleviated cartilage injury and inflammatory response of knee osteoarthritis through PTGS2 PMID 38856914
Neutrophil elastase inhibitors as treatment for COPD PMID 12084007
锌指蛋白 207(ZNF207)基因
An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1 PMID 36810913
Substitution of Alkylphenol Polyoxyethylene Ethers with Bio
Cellular and in vivo activity of JNJ
Desamino lenalidomide
Mito
Structure
Stereocontrolled total synthesis of the potent anti
3,5
The structure of the ferric siderophore binding protein FhuD complexed with gallichrome PMID 10742172
16
DJ
Suppression of PCK1 attenuates neuronal injury and improves post
ALAD
MCE
Promoting Secretion of Pathological Tau Species Using an Induced Proximity Platform That Engages the Autophagy Pathway PMID 40344401
A new small
磷酸腺苷脱氨酶 3(AMPD3)基因
刺猬酰基转移酶样(HHATL)基因
Antiviral activity of MK
Septal Cholinergic Neuromodulation Tunes the Astrocyte
血小板衍生生长因子受体, α多肽(Pdgfra)基因
Receptor tyrosine kinase signalling as a target for cancer intervention strategies PMID 11566607
JQ
Soybean Agglutinin (Biotinylated) (SBA (Biotinylated))
核糖体蛋白 S6 激酶 B1(Rps6kb1)基因
Aplindore (DAB
[Urinary excretion of 4
Identification of flavonoids in Hakmeitau beans (Vigna sinensis) by high
MCE
Luteolin attenuates type 2 inflammation in asthmatic mice induced by OVA by regulating IL
Discovery of ASP5878 Synthesis and structure
Current perspectives on the modulation of thermo
MCE
Highly efficient synthesis of quinoxalinone
氢化可松EP杂质A
Huperzine A attenuates epileptic seizures via enhancing dCA1
The safety, tolerability, pharmacokinetics, and pharmacodynamics of single oral doses of CH4987655 in healthy volunteers target suppression using a biomarker PMID 19934286
Specific PFKFB3 Inhibitor Memorably Ameliorates Intervertebral Disc Degeneration via Inhibiting NF
Developmental toxicity, oxidative stress and immunotoxicity induced by three strobilurins (pyraclostrobin, trifloxystrobin and picoxystrobin) in zebrafish embryos PMID 29859490
PROTAC and Molecular Glue Degraders of the Oncogenic RNA Binding Protein Lin28 PMID 39575661
Galactose
Targeting SLC1A5 blocks cell proliferation through inhibition of mTORC1 in arsenite
Further structure
MCE
An injectable polyacrylamide/chitosan
The action of ryanodine on rat fast and slow intact skeletal muscles PMID 2514259
转录延伸因子 A1(TCEA1)基因
Engineered vesicular cancer vaccines for immunosuppressive microenvironment reversion and in situ vaccine generation PMID 40122241
One
Tissue transglutaminase expression affects hypusine metabolism in BALB/c 3T3 cells PMID 9804167
Proteomic Analysis of Endemic Viral Infections in Neurons offers Insights into Neurodegenerative Diseases PMID 40166347
Mechanical overloading
Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells PMID 28412728
Design, synthesis, and apoptotic antiproliferative activity of novel dihydropyrimidine
Changes in plasma glucose and lactate evoked by alpha and beta 2
Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator PMID 29468715
Acyloxymethyl and alkoxycarbonyloxymethyl prodrugs of a fosmidomycin surrogate as antimalarial and antibacterial agents PMID 36399924
Neural network disturbance in the medial prefrontal cortex might contribute to cognitive impairments induced by neuroinflammation PMID 32505714
Identification of imidazo[1,2
Stereochemistry of viminol, a novel central analgesic PMID 38816
RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation PMID 38514849
Picropodophyllin and sorafenib synergistically suppress the proliferation and motility of hepatocellular carcinoma cells PMID 25289088
T
Structure
Cardiovascular effects of a novel potent and highly selective azaindole
Effects of a serotonin S2
RhoGDI stability is regulated by SUMOylation and ubiquitination via the AT1 receptor and participates in Ang II
Effects and mechanisms of aloperine on 2, 4
MCE
Uncovering the role of TET2
烟酰胺核苷酸腺苷酸转移酶 1(NMNAT1)基因
Sirtuin 1 Is a Potential Target for the Treatment of Neurogenic Intermittent Claudication by Modulating Pyroptosis PMID 40198768
Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris PMID 7296786
Discovery of BI 7446 A Potent Cyclic Dinucleotide STING Agonist with Broad
脂肪酸结合蛋白 6(FABP6)基因
Stxbp1
The protective effects of HIF
Inhibition of mTORC1 by SU6656, the selective Src kinase inhibitor, is not accompanied by activation of Akt/PKB signalling in melanoma cells PMID 24093774
MCE
EZH2 a novel target for cancer treatment PMID 32723346
Chemical inhibition reveals differential requirements of signaling pathways in krasV12
Photo
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery PMID 23398362
Design, synthesis and biological evaluation of novel HIF
Mechanisms of Acetate in Alleviating SETDB1
CH5137291, an androgen receptor nuclear translocation
Cancer chemopreventive activity of 3,5,6,7,8,3',4'
CMX
Miravirsen (SPC3649) can inhibit the biogenesis of miR
Biological effects of prostaglandin E2
Investigating CNS distribution of PF
伸长素 B(ELOB)基因
Discovery of novel rigid STING PROTAC degraders as potential therapeutics for acute kidney injury PMID 40138992
Ginkgolide A enhances FoxO1 expression and reduces endoplasmic reticulum stress to mitigate osteoarthritis in mice PMID 39288630
Anticancer effects of ginsenoside Rk3 on non
Retraction for Su et al., SHP
The DNA Repair Nuclease MRE11A Functions as a Mitochondrial Protector and Prevents T Cell Pyroptosis and Tissue Inflammation PMID 31327667
5
受体相互作用丝氨酸/苏氨酸激酶 3(RIPK3)基因
Thermolysin
Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2 a key enzyme in angiogenesis PMID 10368301
Eupatilin with PPARα agonistic effects inhibits TNFα
CCL1
Design, synthesis, and molecular dynamic simulations of some novel benzo[d]thiazoles with anti
Estrogens revert neutrophil hyperplasia by inhibiting Hif1α
Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum PMID 2422165
18
Discovery of an ALK degrader for lorlatinib
Semaphorin 7A Promotes VEGFA/VEGFR2
Intracellular inflammatory signalling cascades in human monocytic cells on challenge with phytohemagglutinin and 2,4,6
MCE
鼻咽癌
Discovery of 4
A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity PMID 30638931
m
Endogenous epoxygenases are modulators of monocyte/macrophage activity PMID 22028915
Equisetin Targets Intracellular Staphylococcus aureus through a Host Acting Strategy PMID 36354979
IGFBP1
Elevated Src family kinase activity stabilizes E
肾上腺素 A4(EFNA4)基因
Effects of intracerebroventricular l
Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana PMID 12843596
A plant vacuolar protease, VPE, mediates virus
Terrestrosin D, a steroidal saponin from Tribulus terrestris L., inhibits growth and angiogenesis of human prostate cancer in vitro and in vivo PMID 24642631
Large
DNMT3A facilitates colorectal cancer progression via regulating DAB2IP mediated MEK/ERK activation PMID 35063646
MP265 544
Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis PMID 20436488
Pre
Targeting the histone reader ZMYND8 inhibits antiandrogen
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells PMID 29343827
Discovery of Orally Bioavailable FGFR2/FGFR3 Dual Inhibitors via Structure
A chemical biology approach to identifying molecular pathways associated with aging PMID 32705410
SCIMP A Novel Targeted Gene for Postmenopausal Osteoporosis Progression PMID 37057624
Structure
MCE
Review on the Stability Mechanism and Application of Water
MCE
Neuroprotective effect of Notch pathway inhibitor DAPT against focal cerebral ischemia/reperfusion 3 hours before model establishment PMID 30539813
子宫内膜癌 (Endometrial Cancer)
SeSA
Simultaneous determination of L
The Reduced Oligomerization of MAVS Mediated by ROS Enhances the Cellular Radioresistance PMID 32190169
MCE
α
Clec3b
富半胱氨酸的分泌蛋白 1(CRISP1)基因
Mechanism of antifungal activity and therapeutic action of β
The role of loperamide in gastrointestinal disorders PMID 18477966
Il1rl1
信号转导适配器家族成员 2(STAP2)基因
Plasma oxylipin levels associated with preterm birth in preterm labor✰ PMID 33626402
Protein tyrosine phosphatase 1B contributes to neuropathic pain by aggravating NF
Discovery of BI
10929
Thymidine 5'
CT2
Gh
乐贝西林 LCA5(LCA5)基因
[Potential antimalarials. 3. (6
Isoprocurcumenol Supports Keratinocyte Growth and Survival through Epidermal Growth Factor Receptor Activation PMID 34830467
Multifunctional Theranostic Probe Based on the Pim
含 V 组和免疫球蛋白结构域 1(VSIG1)基因
Discovery and identification of a novel PI3K inhibitor with enhanced CDK2 inhibition for the treatment of triple negative breast cancer PMID 37579621
Synthesis and apoptotic induction of sulfonamide
Analysis of segregation distortion and association of the bovine FGF2 with fertilization rate and early embryonic survival PMID 19456315
SJB2
Structural characterization of cationic DODAB bilayers containing C24 1 β
促肌萎缩蛋白 2(SNTB2)基因
MCE
Essential role for cathepsin S in MHC class II
Protein carbonylation during natural leaf senescence in winter wheat, as probed by fluorescein
Focus on monoclonal antibodies targeting B
Chemoproteomic Profiling of Itaconation by Bioorthogonal Probes in Inflammatory Macrophages PMID 32496768
Targeting cancer stem cells with p53 modulators PMID 27074569
H
IFN
Structural basis for the allosteric inhibition of hypoxia
An emerging role for calcium sensitisation in the treatment of heart failure PMID 16004594
Anti
Synthesis of lactoferrin and transport of transferrin in the lactating mammary gland of sheep PMID 1597581
Regulation of heme oxygenase
Evaluation of antiviral activity of compounds isolated from Ranunculus sieboldii and Ranunculus sceleratus PMID 16395649
Neochlorogenic Acid Inhibits Lipopolysaccharide
Effect of the serotonin agonist, MK
Synthesis and biological evaluation of 2',3'
Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases PMID 35542712
一般转录因子 IIA 亚基 2(GTF2A2)基因
Targeted p53 activation by saRNA suppresses human bladder cancer cells growth and metastasis PMID 27012825
Caspase
CD314/NKG2D 抗体 (YA3918)(CD314/NKG2D Antibody (YA3918))
Bis(2
m
WRN
MCE
Platycodin D Ameliorates Type 2 Diabetes
A new triterpene and anti
Djenkolic acid 498
Leonuriside B 222639
IL
F 2692 133220
PSB
TRIM29 Human Pre
FXR agonist 16 3099198
SSRP1 抗体 (YA9590)(SSRP1 Antibody (YA9590))
MCE
SETD8 promotes stemness characteristics and is a potential prognostic biomarker of gastric adenocarcinoma PMID 33127342
Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers Understanding and improving key determinants of pharmacological properties PMID 27268696
MyomiRs
Interferon regulatory factor 1 (IRF
Synthesis and biological evaluation of N
Nifuratel Induces Triple
4,6
Gluconate
[The role of beta 2
Royleanonic acid (木香醌酸)
Demethylase FTO Regulates P2X3R Expression Contributing to the Mechanism of Hyperalgesia in Lumbar Disc Herniation PMID 40170503
(Rac)
MCE
Gallic acid induces necroptosis via TNF
Verenafusp alfa
Efficacy of the PSD95 inhibitor Tat
The role of AMPK
VAF347 574759
Spiramycin
Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury PMID 29438804
Nanaomycin A selectively inhibits DNMT3B and reactivates silenced tumor suppressor genes in human cancer cells PMID 20833755
Lenvatinib versus sorafenib in first
L
5
MCE
Anti
Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold PMID 34463505
Swainsonine inhibits proliferation and collagen synthesis of NIH
TGF
Trimethylamine N
Oral administration of GW788388, an inhibitor of TGF
DKN 01
Discovery and evaluation of 3
Efflux inhibitor
Zbtb1 Rat Pre
PCSK9
Synthesis and evaluation of novel podophyllotoxin analogs PMID 22658864
TCEP
cRGD enables rapid phagocytosis of liposomal vancomycin for intracellular bacterial clearance PMID 35235809
GLPG2222
MPG, HIV related
CTDSPL2 promotes the progression of non
AF1, a sequenced bioactive neuropeptide isolated from the nematode Ascaris suum PMID 2627377
Diftalone 21626
TMEM236 Human Pre
Raddeanin A Induces Apoptosis and Cycle Arrest in Human HCT116 Cells through PI3K/AKT Pathway Regulation In Vitro and In Vivo PMID 31239864
Surfen, a small molecule antagonist of heparan sulfate PMID 18725627
Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5
神经肽
ID2 and GJB2 promote early
The influence and the mechanism of docosahexaenoic acid on a mouse model of Parkinson's disease PMID 21736911
Oncostatin
PARP
Jiedu Fuzheng decoction improves the proliferation, migration, invasion and EMT of non
Diagnostic Competence of Creatine Kinase BB, in Mild Traumatic Brain Injury and its Prognostic Value PMID 37200752
organic nitrogen
VMD928
Cobicistat
Antibacterial agent 74 1644387
ENPP1
groove
Spg21
PAR 1141
MCE
CP 283097
N,O
Effects of a novel mGlu₂/₃ receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid PMID 21847569
Maresin1 regulates neutrophil recruitment and IL
MNAC 13
PF1367550
SB
Pde4d Mouse Pre
Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells PMID 15374684
LDH
SCH
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