最近收录_第795页_生物活性分子
生物活性分子最近更新
Design, synthesis, and biological evaluation of 4
Kigamicin B 680571
Discovery of a novel allosteric inhibitor scaffold for polyadenosine
The role of myostatin in muscle wasting an overview PMID 21966641
Structural and mechanistic determinants of a novel site for noncompetitive inhibition of GluN2D
ABBV 2222
TAMRA
TAMRA
2
NRMA
Visualizing the Regulation of Hydroxyl Radical Level by Superoxide Dismutase via a Specific Molecular Probe PMID 29237269
Carcinoma
RN613
Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment PMID 27666947
thermogenesis
Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP) PMID 17502136
Structural insights into the redox regulation of Oncomelania hupensis TRP14 and its potential role in the snail host response to parasite invasion PMID 35988710
Enhanced expression of coxsackievirus and adenovirus receptor in lipopolysaccharide
Enzastaurin 170364
IL3RA
DBCO
PXR activation
Calcitonin (salmon) 47931
Monastrol inhibition of the mitotic kinesin Eg5 PMID 15665380
Stampidine is a potential nonspermicidal broad
p
IL
DEAC
Design and synthesis of chloroquine analogs with anti
Doxorubicin suppresses chondrocyte differentiation by stimulating ROS production PMID 34547383
Bodilisant
Enpatoran 2101938
SLC23A2 Human Pre
Ifrd1 Rat Pre
disperse
Fgf4 Rat Pre
MCE
Slight up
IFNE Human Pre
CAPAN
Geniposide ameliorates chronic unpredictable mild stress induced depression
A specific inhibitor of CDK1, RO
centrally
Zilebesiran 2380166
TNFRSF1B
Atorvastatin 134523
JS
CYD
protein tagging
VPC12249 ammonium 799268
2
TUG2208
UC781
Amino
NAMPT
Potential value of immunogenic cell death related
Angptl7 promotes insulin resistance and type 2 diabetes mellitus by multiple mechanisms including SOCS3
TH1020
Novel TIE
lymphocytic\
PPHLN1 Human Pre
CD2 Immunobiology PMID 32582179
PD147953
Mat2a
isoG Nucleoside
ALX
Camphorquinone 10373
DENV
Puromycins B
Herbicidal agent 11 3026829
Catalytic activities of wild
GZNL
SUB1
A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment PMID 31826303
Crofelemer for the treatment of secretory diarrhea PMID 22149578
SLC34A3
ASAP3 Human Pre
A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin PMID 27600840
diterpenic
apoptosome
HPi1 13080
BIBU52
PY159
Has2
PD099560
Small
SQ609
MS 4077
DBA/1J
Hyoscine
EM 343
Design, synthesis, and biological evaluation of 14
A network pharmacology
3
SLC2A12 Human Pre
OATD
Discovery of AM
Elironrasib 2641998
SD17B13
cell protectant
MPC
Mal
JR
Bemiltenase alfa 2766038
Aspirin and other cyclooxygenase inhibitors new therapeutic insights PMID 15199473
SR1903
MDM2/4
BMS875944
PD
BF175
Dammarane triterpenes from the hypocotyls and fruits of Ceriops tagal PMID 16378377
MCE
NB
TNX
BUdR
SBP 2
safety
Cis
SL
FtsZ
N2
Aplaviroc
Dapoxetine
anesthetic activity
CD30 is a CD40
Soluble CSF1R alleviates microgliopathy in a CSF1R
Neuroprotective effect of Ginsenoside Re against neurotoxin‑induced Parkinson's disease models via induction of Nrf2 PMID 35543148
The Extract of Arctium lappa L. Fruit (Arctii Fructus) Improves Cancer
Genomic targets of the IRE1
Inhibition of enhancer of zeste homolog 2 prevents corneal myofibroblast transformation in vitro PMID 33992624
Oxidative decarboxylation of salsolinol
NK8116
Matr3 Rat Pre
CT 133
Linderaspirone A 1235126
(DHQD)2PHAL
L 674573
tetraploid
CER5
PRKACA
Cap
3
ELA
ShK
L
Emoghrelin
hGluR5
Dornase alfa 143831
Design and Optimization of Novel Sulfoximines as Low Bee
Usmarapride free base 1428862
JNK
BAY
KIF18A
SC
ADB
94G6
IFNγ
Col2a1 Rat Pre
Methoxy isobutyl isonitrile 109434
SWTX
human lung
ONO
PD 131628 127967
ICI 56780 28130
breastfeeding
OTSSP167 1431697
PROTAC ALK degrader
Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosome PMID 17967466
Circadian misalignment promotes vascular smooth muscle cell apoptosis via defective autophagy PMID 34131827
Osteocytes promote osteoclastogenesis via autophagy
Hongotoxin1
Δ14
DS02312223 2253733
Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid
Taurodeoxycholate increases intestinal epithelial cell proliferation through c
Ozarelix 295350
PGV1
S
DHW
GSK
RL cells
Spermatinamine, the first natural product inhibitor of isoprenylcysteine carboxyl methyltransferase, a new cancer target PMID 17964784
Dibenz[a,h]anthracene
C11
(Rac)
Fev
VYR006
Umami agent
OX2R
Anti
NAV 006
TDR32750
phenol
ARA 290
CD80
CD69
coffee beans
LY2940680
JNJ678
Pold2 Rat Pre
Boc
2('),3(')
NRPSs
LB
CRBN ligand
HB 35018
Trpm4
Syndecan
TH
Forestine 91794
autophosphorylation
GDC4379
RO
Ispronicline 252870
Macrocarpal L
Analysis of ocular fluid in patients with ranibizumab
Discovery of 3,4
Interferon
The enzyme 4
Antitumor agent
SU11248
UCM
3
BMS 135
Ferroptosis inducer
Cellular Target Proteome in Breast Cancer Cells of an Oplopane Sesquiterpenoid Isolated from Tussilago farfara PMID 32881525
menin
Lhx9 Mouse Pre
polyacetylene alcohol
Du011 890818
rFLS
1,3
Focal Adhesion Kinase Orchestrates GLUT4 Translocation and Glucose Uptake via Cytoskeletal Turnover in Primary Adipocytes PMID 40396386
Fellutanine A 175414
AG06827
TNFSF9
ABT
Farobin B 1245447
MCE
YM
Ptaquiloside
VX
MCE
Bradykinin B1 receptor antagonist 1 578727
CCL23 a new CC chemokine involved in human brain damage PMID 29415332
Drug Intermediate
Daphnicyclidin F
rBCATm
Cabotegravir
Wnt pathway inhibitor 3 663213
SRK181
Antiviral agent 41 68622
804CB
Antifungal Exploration of Quinoline Derivatives against Phytopathogenic Fungi Inspired by Quinine Alkaloids PMID 34623798
5
Chinensine B 849245
Pancreastatin (swine)
Myricetin
Self
5
Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives New Directions for Inhibitors Design PMID 24900786
Direct and Indirect Regulators of Epithelial
ATTO 425 azide 1609584
EMB
Autophagy activator
Targeting Protein Tyrosine Phosphatase Nonreceptor Type 2 with a Novel Inhibitor for the Treatment of Melanoma PMID 41204903
EPZ
Cucurbitacin B exerts neuroprotection in a murine Alzheimer's disease model by modulating oxidative stress, inflammation, and neurotransmitter levels PMID 35227014
Histone H3 methyltransferase Ezh2 promotes white adipocytes but inhibits brown and beige adipocyte differentiation in mice PMID 33571671
HP
MRS8432
MGS
TSHZ2 Human Pre
13'
27
RVD
Asperilin
CAD
halflives
Utibaprilat
(±)14(15)
(R,R)
TAT
Synthesis of isatin based N1
3
Vildagliptin impurity 24 214398
R24571
t
Furazidine
2,5
Suricapavir 2417270
Vasculotide 1359657
Sialorphin 131748
CT
BMS466442
NMS
[Des
DDX31 Human Pre
CLDN5 Human Pre
Matteson Homologation
Fleroxacin
Il1f10
NPC
centered
表面活性蛋白 A1（SFTPA1）基因
Aminozolamide
Structural and PK
Epigallocatechin Gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea PMID 23201840
Chemoproteomics reveals microbiota
19
BIIE
Saikosaponin C 20736
L
DNA religation
Nonsymmetrically Substituted 1,1'
Olamufloxacin (HSR
Benzoquinoquinoxaline 207671
L
SB 271046 Hydrochloride 209481
AdemA
Besifovir Dipivoxil 441785
1
Benzyl (8
An integrated network pharmacology, molecular docking and experiment validation study to investigate the potential mechanism of Isobavachalcone in the treatment of osteoarthritis PMID 38310989
(+)
4
Altered cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation PMID 39282272
Inhibition of the mitochondrial F1F0
(S)
PF
CID15997213 900134
干扰素α诱导蛋白 6（IFI6）基因
Caesalpine B
Vectofusin 1
S
Pocapavir (Standard)
Contribution of CYP3A isoforms to dealkylation of PDE5 inhibitors a comparison between sildenafil N
Sildenafil, N
[Complexation between triterpene glycosides of holothurians and cholesterol is the basis of lipid
Triterpenes from Garcia parviflora. Cytotoxic evaluation of natural and semisynthetic friedelanes PMID 20958014
Valproic acid β
Gd
VGF
Estrogen influences the transzonal projection assembly of cumulus
Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection PMID 23093945
Effects of Resistance
A high throughput screen for TMPRSS2 expression identifies FDA
Interaction of a substance P agonist and of substance P antagonists with lipid membranes. A thermodynamic analysis PMID 1372515
PSD95 抗体 (YA4134)（PSD95 Antibody (YA4134)）
tert
Design, synthesis, and biological studies of novel sulfonamide derivatives as farnesoid X receptor agonists PMID 37413879
Activity of Debio1452, a FabI inhibitor with potent activity against Staphylococcus aureus and coagulase
Rhein 8
ADX 71441
Bid Mouse Pre
Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D3 Receptor
Discovery of a Novel Orally Active, Selective LPA Receptor Type 1 Antagonist, 4
Cantharidin overcomes IL
A high
白细胞介素 13（IL13）基因
Comparative disposition of tripelennamine in horses and camels after intravenous administration PMID 11110101
The novel compound Sul
Metabolites with Gram
EVP
Neonatal Malignant Disorders Germ Cell Tumors PMID 33583501
LY163502
5(6)
Rizavasertib (Standard)
Integrated computational screen and validation of thalidomide
Mechanism of inhibition of MMTV
MCE
Crp
Promoting in vivo remyelination with small molecules a neuroreparative pharmacological treatment for Multiple Sclerosis PMID 28256546
Identification of metabolites from an active fraction of Cajanus cajan seeds by high resolution mass spectrometry PMID 27283694
High
SPINK6 Promotes Metastasis of Nasopharyngeal Carcinoma via Binding and Activation of Epithelial Growth Factor Receptor PMID 27671677
The interaction between 20
Identification and analysis of gene families from the duplicated genome of soybean using EST sequences PMID 16899135
Protection by picolinamide, a novel inhibitor of poly (ADP
Macrophage polarization in vitro and in vivo modified by contact with fragmented chitosan hydrogel PMID 34723433
Inter
MX69 1005264
A broad
Identification of 1,5
Inhibitory effects of p
H
Asperlin induces G₂/M arrest through ROS generation and ATM pathway in human cervical carcinoma cells PMID 21600879
Evaluation of the toxicity of herbicide topramezone to Chlorella vulgaris Oxidative stress, cell morphology and photosynthetic activity PMID 28525816
Quantification of 1,3
MCE
Novel functions of grass carp three p40 isoforms as modulators of Th17 signature cytokine expression in head kidney leukocytes PMID 31734285
Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection PMID 35568375
MicroRNA
含 tectonin β
L
Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination PMID 25218293
On the role of the immunoproteasome in transplant rejection PMID 30220008
Sabutoclax 1228108
alpha
[Expeimental studies in animals on a new lipid lowering compound etiroxate hydrochloride (author's transl)] PMID 582735
Differential action of chlorinated polycyclic aromatic hydrocarbons on aryl hydrocarbon receptor
Structure
ABSOLUTE CONFIGURATION AND BIOLOGICAL PROPERTIES OF ENANTIOMERS OF CFTR INHIBITOR BPO
Newer antibacterials in therapy and clinical trials PMID 23181224
Epidemiology of pervasive developmental disorders PMID 19218885
TNF
Design, synthesis and biological activity of novel substituted 3
Photo
Inhibiting IL
Discovery of P11
Melanoma tumors acquire a new phospholipid metabolism phenotype under cystemustine as revealed by high
Biophysical characterization of the new human ether
BB 0305179 2512200
Mechanisms underlying the renoprotective effect of GABA against ischaemia/reperfusion
Angiotensin II
Effects of inhaled glaucine on pulmonary responses to antigen in sensitized guinea pigs PMID 10844113
Migrastatics
H1PVAT is a novel and potent early
Insulin action and resistance are dependent on a GSK3β
On the mechanism of action and selectivity of the corn herbicide topramezone a new inhibitor of 4
Kinetics and dynamics of the peripheral neurokinin
Suppression of ornithine decarboxylase gene expression by retinoids in cultured human keratinocytes PMID 2295835
Synthesis, characterization, and cellular localization of a fluorescent probe of the antimalarial 8
Construction of optimized bispecific antibodies for selective activation of the death receptor CD95 PMID 18281499
Angiotensin type 1 receptor blockers induce peroxisome proliferator
2
Liposome
Nps
MCE
Discovery of 6
Elaeocarpionoside, a megastigmane glucoside from the leaves of Elaeocarpus japonicus Sieb. et Zucc PMID 20091243
A cytotoxic butenolide, two new dolabellane diterpenoids, a chroman and a benzoquinol derivative formosan Casearia membranacea PMID 12898426
Living
NGB 2904 hydrochloride 189061
BL
Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes PMID 681249
Design and synthesis of Prostanoid EP4 receptor antagonists for treatment of inflammatory pain PMID 40976187
Importance of intracellular angiotensin II in vascular smooth muscle cell apoptosis inhibition by the angiotensin AT1 receptor antagonist irbesartan PMID 17509562
Activation of beclomethasone dipropionate by hydrolysis to beclomethasone
N
Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti
Fluorescein
Mechanism for the nonlinear pharmacokinetics of erythropoietin in rats PMID 9353365
New inhibitors for expression of IgE receptor on human mast cell PMID 20202836
NH2
Gastrazole free acid 174610
PGC
Serotonin receptor 5
MCE
Development of β
HA1/Hemagglutinin 蛋白, H1N1 (AAD17229, HEK293, His)
Identification and validation of mitophagy
SNPB 663598
Effect of E
1,4
Cardiolipin
PROTAC FLT3/JAK2/BRD4 Degrader
MCE
Kinetics of autocatalytic zymogen activation measured by a coupled reaction pepsinogen autoactivation PMID 16207090
Timosaponin A1 68422
A protective role by interleukin
ATTO 725 Carboxy
Bioactive imidamide
Butylamine
Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis PMID 27667686
Targeting of REST with rationally
Kash5
Roles of Mitochondrial Serine Hydroxymethyltransferase 2 (SHMT2) in Human Carcinogenesis PMID 34476002
MCE
Simultaneous determination of 2',3'
Estrogen receptor beta in lateral habenula mediates antidepressant effects of estrogen in postpartum
Fibroblast growth factor
胰岛素受体相关受体（INSRR）基因
MAP4K4
Antiviral effects of simeprevir on multiple viruses PMID 31563599
Piperacetazine 3819
The hepatoselective glucokinase activator PF
A selective S
m
Adefovir diphosphate 129556
中心体蛋白 57（CEP57）基因
Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)
TLR9
Inhibitor of DNA binding 2 (ID2) regulates the expression of developmental genes and tumorigenesis in ewing sarcoma PMID 35422476
D
METTL3 enhances the stability of MALAT1 with the assistance of HuR via m6A modification and activates NF
Thalidomide
DENV
tau 微管蛋白激酶 2（TTBK2）基因
TP53 Mutations Promote Immunogenic Activity in Breast Cancer PMID 31275382
Inhibition of CDK4/6 Promotes CD8 T
Disodium 6,6′
IKBIP promotes tumor development via the akt signaling pathway in esophageal squamous cell carcinoma PMID 38914958
Dimethylsildenafil 1416130
Canine factor X (Stuart
Integrated pharmaco
CRL4DCAF8 dependent opposing stability control over the chromatin remodeler LSH orchestrates epigenetic dynamics in ferroptosis PMID 33288900
Highly selective DNA aptamer sensor for intracellular detection of coenzyme A PMID 40206557
Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis A Single
共964页
首页
上一页
800
799
798
797
796
795
794
793
792
791
790
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新