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Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC
mTOR contributes to endothelium
Implication of the ryanodine receptor in TRPV4
Increased GABBR2 Expression on Cell Membranes Causes Increased Ca2 + Inward Flow, Associated with Cognitive Impairment in Early Alzheimer's Disease PMID 39724481
Cyclophilin D
Leptin combined with withaferin A boost posthemorrhagic neurogenesis via activation of STAT3/SOCS3 pathway PMID 38714285
Terazosin attenuates abdominal aortic aneurysm formation by downregulating Peg3 expression to inhibit vascular smooth muscle cell apoptosis and senescence PMID 38331337
α
Transition
Degradation of Polycomb Repressive Complex 2 with an EED
Extensive jejunal injury is repaired by migration and transdifferentiation of ileal enterocytes in zebrafish PMID 37342912
BAY
A targetable HB
Synthesis and evaluation of in vivo antioxidant, in vitro antibacterial, MRSA and antifungal activity of novel substituted isatin N
Pharmacology of AM803, a novel selective five
Administration of a human monoclonal antibody (TUVIRUMAB) to chronic hepatitis B patients pre
Butyric acid
脑表达 X 连锁 2（BEX2）基因
Oleanane
SIB1757
Cnn1 Mouse Pre
Concentrations of oxidized linoleic acid derived lipid mediators in the amygdala and periaqueductal grey are reduced in a mouse model of chronic inflammatory pain PMID 30103924
Tfr2
Beryllon II 51550
AB452
Lebrikizumab treatment in adults with asthma PMID 21812663
MCE
KRAS inhibitors may prevent colorectal cancer metachronous metastasis by suppressing TGF‑β mediated epithelial‑mesenchymal transition PMID 39540351
Quantitative and systems pharmacology 2. In silico polypharmacology of G protein
M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures PMID 28145455
circCRKL, a circRNA derived from CRKL, regulates BCR
Hirsutine induces mPTP
LAT 抗体 (YA3161)（LAT Antibody (YA3161)）
Edotreotide 204318
Nintedanib inhibits growth of human prostate carcinoma cells by modulating both cell cycle and angiogenesis regulators PMID 29934570
Synthesis and anti
Development of novel affinity reagents for detecting protein tyrosine phosphorylation based on superbinder SH2 domain in tumor cells PMID 30143211
Sulfonamide
Deficiency of Perry syndrome
Bone marrow mesenchymal stem cell
Chemical reprogramming of human somatic cells to pluripotent stem cells PMID 35418683
Viracept (nelfinavir mesylate, AG1343) a potent, orally bioavailable inhibitor of HIV
Kalirin mediates Rac1 activation downstream of calcium/calmodulin
6
SIN3B Loss Heats up Cold Tumor Microenvironment to Boost Immunotherapy in Pancreatic Cancer PMID 39316363
Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes PMID 30799288
RKI
16 0 2
CCG
LD 114
SMANT hydrochloride 1177600
RMC6291
Zirconium
GLB1/Beta
secretagogue
Anti
Salmeterol
N
PANC
Fluoroquinolone
Anti
NKG2D/CD314 蛋白, Human (HEK293, His)
Bilaid B 2393866
RSL1D1 Human Pre
PTC
Mibefradil dihydrochloride 116666
LNT
Terrein
dTAG Targeting Ligand 1 755039
JZP
Effects of erlotinib on lung injury induced by intratracheal administration of bleomycin (BLM) in rats PMID 20686337
BI 99179 1291779
Dipyrithione (Standard)
In vivo transcriptomic, functional, circuit
1,3,7
2
HSF1 抗体 (YA896)（HSF1 Antibody (YA896)）
Poloxamer 212 (L72) (PEG
CY
A549
PS
BPH
Cys474
TpD 1273551
D816Y
Adoprazine hydrochloride 222551
PLLA3000
σ1
RR
glycopeptide
UO
Hirudinoidine A 1021944
Tauroxicum
Protein deglycase DJ
B4GALT5 Human Pre
PF4522654
Wnt/LRP5
CLK1/4
DSPE
LY3325656
Enestroburin
Demethyl
CD72
JX
Usistapide
Hspg2 Rat Pre
BZ 55
Dpt
Zhx2 Rat Pre
P
OARV771
HCFC2 (Host cell factor C2) 抗体 (YA8594)（HCFC2 (Host cell factor C2) Antibody (YA8594)）
Kif3c Rat Pre
MCE
RO7185876
Pulrodemstat 1821307
A Mechanism
Caf1
MCF7 cells
rescued
VX
PDK
IITZ 02
Denthyrsinin 118169
LCR 323
RTA 401
biofuel
NS
DDAN
Calcium alginate
Caco
ALXN1720
WN1316 1356959
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF
In vitro and in vivo anti
Absorption, metabolism, and excretion of [14C]vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans PMID 19074975
H
ZL3B
Terbutalone 139508
Thalidomide
HBP 08
stable metabolic
Rebamipide impurity3
SHK
R
TH
NSC 178248
Y16524
Molidustat
mitochondrial uncoupler
Inhibitory effects of nicorandil, a K ATP channel opener and a nitric oxide donor, on overactive bladder in animal models PMID 18070173
Millepachine
RH01386
MK
SCC7 cells
12,13
Mal
protease substrate
L 684248 156728
1
Rediocide A
SEI
N
Anandamide prodrugs. 1. Water
BMS
MRE0094
machinery
Cinnamohydrazide
Danthron (Standard)
TRPM8 receptor agonist
Win
BOL 148
STAT3
Trimethoprim
(E)
BRL
Betalains
MK
R
MS 8815
GPi 819
3a
CYD
ZK91296
JCP 170
Apricoxib
A
DTS 108
Atazanavir
Ddx19b Rat Pre
Tet
Notiretatug
Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases PMID 3928324
The BAX
Sp2
TLR9
RK
Cib1 Mouse Pre
THR 123
Improved clearability of cystic fibrosis sputum with dextran treatment in vitro PMID 9517580
Boeravinone E
Biotin
SUVN
Kitamycin A 225939
Y4R agonist
6
Tril Rat Pre
Targeting the USP7
BI409306
KX
PIF1
Discovery of novel substituted pyridine carboxamide derivatives as potent allosteric SHP2 inhibitors PMID 39303516
SB
Heart regeneration opportunities and challenges for drug discovery with novel chemical and therapeutic methods or agents PMID 24470316
brain homogenates
PLAGL1 Human Pre
M
Cefalonium dihydrate 1385046
细胞周期蛋白依赖性激酶 11A（CDK11A）基因
TM 6008
KRAS KT
C14
Vonoprazan impurity 46 2169267
Benzgalantamine
antiangiogenetic
SK 56
GL
LNP Lipid48
MC
Raw and salt
PTEN
Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase PMID 12213066
derived peptides
Antitubercular agent
Eltrombopag
Developmental toxicity of amesergide administered by gavage to CD rats and New Zealand white rabbits PMID 8529820
Norbiotinamine
CP
TACC3 inhibitor 1
Bendroflumethiazide
iRGD peptide 1392278
Glycerol
pain
KD6001
Phosphorylation of human microtubule
RFC2 Human Pre
15
NSC 95682
DCN1
PP487 1092787
细胞色素 b
CPM
rheology
FSK hydrochloride 3033987
HSD17B13
L
NLRP3
BCN
Lasmotinib 2127107
CHET 3
NFX179
Alleviation of mutagenic effects of polycyclic aromatic agents (quinacrine mustard, ICR
Mavatrep 956274
Effects of hydroxymetabolites of bupropion on nicotine dependence behavior in mice PMID 20576796
PBI0451
Peptide 78
Application of the antitussive agents oxelaidin and butamirate as anti
SMMC
Extracellular Nucleotides Affect the Proangiogenic Behavior of Fibroblasts, Keratinocytes, and Endothelial Cells PMID 35008664
Pyridone
bait agent
P110δ
Cyclo(
Depemokimab 2243274
temperature resistance
Pdia6 Rat Pre
Hydroxyquinoline
NGD 98
L631529
Miclxin 2494198
CHFR 蛋白, Human (His)
L82
Axl
IACS
Real Thiol 2280796
DC432 2388988
NEDDylation
Heterogeneity of protein kinase C
Precise control of apoptosis via gold nanostars for dose dependent photothermal therapy of melanoma PMID 31675048
6
dismutases
WAY 818
Sliding Hydrogels Reveal the Modulation of Mechanosensing Attenuates the Inflammatory Phenotype of Osteoarthritic Chondrocytes in 3D PMID 39718447
NIC
Ergosterol peroxide glucoside
MCE
MG
PI3Kα
A
Safety, pharmacokinetics, and antiviral activity of A77003, a C2 symmetry
Dihydro
AG
Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism PMID 34928601
Interaction of calf thymus DNA with the antiviral drug Lamivudine PMID 21721935
MK2
Montirelin
Phoslactomycin E 159991
Escherichia
亚美异粟碱
MGLL 蛋白, Human (His)
GPI membranes
Dyrk1A
BI
Spg21 Rat Pre
Phenelfamycins D 118498
aged mice
LCB
prolactin secretion
CM
SGI
TST1N
AKI
PPARγ modulator
Pharmacologic properties and mechanism of action of amfonelic acid PMID 4393073
The role of microglial P2X7 modulation of cell death and cytokine release PMID 28716092
2
Effect of 1
1
Ki
Sphingolactone 24
Nrf2 activator 17 3059044
BY
PSMA targeting peptide 2042750
Phenylpyropene A
ISIS678354
Biotin
Acridine Orange A Review of Novel Applications for Surgical Cancer Imaging and Therapy PMID 31612102
VU319
PF
Mu opioid receptor antagonist 9
Antitubercular agent
KYSE70
Immunizing Hapten
CM 414
SB1295
Antibacterial agent 42 1426572
HCC
PRO70769
allo
BP Fluor 555 azide 2770422
Y06137 2226534
Fyn 抗体 (YA5237)（Fyn Antibody (YA5237)）
Mca
MCX 28 1414453
β5i
MK
N
Zerumbone
Anti
CBR1
total cholesterol (TC)
Monoamine Transporter
JAK
Seliciclib Carboxylic Acid
Hedgehog
Kakuol
Piperacetazine directly binds to the PAX3 FOXO1 fusion protein and inhibits its transcriptional activity PMID 37732905
Raja42
APOE
BCX 5
BH3I
TLX oligomerization
Human IgG
Helodormin
NXL
Cortisone
phosphorylated Smad 2
iAfaPhos1
Salicortinol 1176656
Suppressive effect of post
Calendic acid
细胞粘附分子 2（CADM2）基因
NIA11092
L
FGFR
phenoxy substitution
Mogamulizumab, an anti
iodine
Iso sildenafil
Identification of mouse AAV capsid
Are alpha
MK7690
TG
TDI11055
Lys
Caspofungin diacetate 179463
JMV 236 113137
Irbesartan 138402
Prime Editing Mechanistic Insights and DNA Repair Modulation PMID 39996750
DMTr
synthetase
IKK
Apixaban impurity41
Isosojagol 94390
The selective estrogen receptor modulator acolbifene reduces cholesterolemia independently of its anorectic action in control and cholesterol
Plecstatin1
OATP1B1
CGS
A
Fascaplysin
KLHL24 Human Pre
PF
Prion Protein
F 9170
TRPM8 antagonist 4 prodrug
memory consolidation
BoNT/E
p
pan
Luxabendazole
midshaft
MCE
IMP
LXB 4
YYA
(Rac)
MTR 106
PAV174
Ozekibart 2539847
Assessment of antiviral activity, efficacy, and toxicity of prostaglandin A2 in a rabbit model of herpetic keratitis PMID 8891139
WAY150138
Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity PMID 11277514
recombinant enzyme
Cotargeting Androgen Receptor and Clusterin Delays Castrate
CXA
Muscarinic acetylcholine receptor M1 mediates prostate cancer cell migration and invasion through hedgehog signaling PMID 30027929
FPL 62129
ODN1982
DDX55 safeguards naïve T cell homeostasis by suppressing activation
Sdc4
Flt3
Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17
Trpv5 Rat Pre
PG116800
LNP Lipid5
Discovery of biological evaluation of pyrazole/imidazole amides as mGlu5 receptor negative allosteric modulators PMID 23434029
Qi site
ITGA4
Synthesis, Fungicidal Activity, and Molecular Docking of 2
含锚蛋白重复和 SOCS 盒 13（ASB13）基因
Debio
The immunosuppressive activity of L
CRT
Tangshenoside V 1050399
CHIR
RNA
Cladosporin, a new antifungal metabolite from Cladosporium cladosporioides PMID 5169000
Aspirin Eugenol Ester Alleviates Vascular Endothelial Ferroptosis by Enhancing Antioxidant Ability and Inhibiting the JNK/c
Red Ginseng Improves D
CB6644
NRMA 7
Protection of mice from endotoxic death by 2
Thienopyrimidinone Derivatives as a GluN2B/C/D Biased, Positive Allosteric Modulator of the N
Cardiolipin remodeling by ALCAT1 links hypoxia to coronary artery disease by promoting mitochondrial dysfunction PMID 34111561
Zelandopam
RBBP8
5
Cys imaging
HIV
BChE
Anti
Formulation and characterization of transfersomes for ocular delivery of tonabersat PMID 40327409
Biological applications of a turn
SR16835
JCP 174
Glucoside
Fluopimomide 1309859
Abituzumab 1105038
Zandelisib
GLP
MK591
T
3
Endothelial indoleamine 2,3
L
Perfluoropentanesulfonic acid (PFPeS)
Flaccidin
EXP 3179
PD
S55746 1448584
Design and synthesis of novel 3,7
ABT 702
Valsa mali
LIK066
FGFR
2',7
A71915
REA 抗体 (YA1848)（REA Antibody (YA1848)）
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation PMID 31913317
NP
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