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The protective effects of Salusin
Valtrate alleviates inflammation by targeting USP9X to enhance NLRP3 degradation PMID 40378590
Sulfo
Human alpha B
Structure
Inhibition of D
ABP 215 1438851
sEH
AZD7624 (Standard)
USP7 promotes endothelial activation to aggravate sepsis
AO
Cell proliferation in spiral ligament of mouse cochlea damaged by dihydrostreptomycin sulfate PMID 10380736
Aerobic Exercise Attenuates Autophagy
New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer PMID 11004678
rel
Epigenetic mechanisms mediate cytochrome P450 1A1 expression and lung endothelial injury caused by MRSA in vitro and in vivo PMID 39588951
5
A novel method for synthesis of α
FABP5 reprograms lipid metabolism and promotes cutaneous T
P
Volucrin 130217
Prevention of CaCl2
Effects of lncRNA TUSC7 on the malignant biological behavior of osteosarcoma cells via regulation of miR
P
Suppression of voltage
1,1'
Iron(II) phthalocyanine Loaded and AS1411 Aptamer Targeting Nanoparticles A Nanocomplex for Dual Modal Imaging and Photothermal Therapy of Breast Cancer PMID 32848397
CFTR Modulators for the Treatment of Cystic Fibrosis PMID 25083129
The protein kinase CPK28 phosphorylates ascorbate peroxidase and enhances thermotolerance in tomato PMID 33711164
Doramectin attenuates inflammation, obesity and insulin resistance in food
Elevated serum uric acid level was a notable adverse event during combination therapy with sofosbuvir and ribavirin PMID 28834004
TbPTR1 inhibitor 1 2499713
Amplifying antigen
Cromolyn Reduces Levels of the Alzheimer's Disease
PD
METTL3
Rhein suppresses osteosarcoma progression via modulating the miR
Inhibition of Src kinases by a selective tyrosine kinase inhibitor causes mitotic arrest PMID 10626805
[Ethacrynic acid inhibits airway smooth muscle contraction in mice] PMID 31879742
Inhibition of autophagy reduces the rate of fluoride
APN
CREB3 Human Pre
Importin subunit beta
SYN023, a novel humanized monoclonal antibody cocktail, for post
Aspartylglycosamine is a biomarker for NGLY1
Rac1 regulates nucleus pulposus cell degeneration by activating the Wnt/β
EBNA1
Oleamide and anandamide effects on food intake and sexual behavior of rats PMID 15193744
Evaluation of the β
Transport Mechanism of Coumarin 6 Nanocrystals with Two Particle Sizes in MDCKII Monolayer and Larval Zebrafish PMID 27159431
Monophosphoryl Lipid A
Design, synthesis, antiproliferative activity and docking studies of quinazoline derivatives bearing 2,3
Precision pore structure optimization of additive manufacturing porous tantalum scaffolds for bone regeneration A proof
m
Recombinant human insulin
Givinostat hydrochloride 199657
Molecular conformation
Sitagliptin regulates the AMPK/NF
Regenerating islet
16,16
EZH2 Regulates Intestinal Inflammation and Necroptosis Through the JNK Signaling Pathway in Intestinal Epithelial Cells PMID 31273598
Assessment of spiramycin
Attenuation of sn
Combining Data
Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells PMID 34873640
METTL3 promotes the progression of non
Advances in Orphan Nuclear Receptor Pharmacology A New Era in Drug Discovery PMID 32219209
N
Proxodolol free base
OTU 去泛素化酶，泛素醛结合 2（OTUB2）基因
CD98 蛋白, Rat (HEK293, Fc)
Novel designer receptors to probe GPCR signaling and physiology PMID 23769625
Eco
Multisubstituted indole
Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding PMID 16759105
Administration of recombinant rhesus interleukin
Inhibition of human interleukin
Inhibition of the activity of Rho
ICAM
Biotin
The family of the interleukin
dCeMM2 296771
DUT
Kinetic properties of glucose 6
Malolactomycins C and D, new 40
NKG2C
Milbemycins, a new family of macrolide antibiotics fermentation, isolation and physico
CALMODULIN6 negatively regulates cold tolerance by attenuating ICE1
RARRES2 regulates lipid metabolic reprogramming to mediate the development of brain metastasis in triple negative breast cancer PMID 37491281
Docosatrienoic acid sodium 2692623
Fcrl6 Mouse Pre
Tolperisone hydrochloride 3644
Methylenedisalicylic acid(mixture of isomers) 27496
Pyriftalid 135186
Upregulation of Phosphodiesterase 7A Contributes to Concurrent Pain and Depression via Inhibition of cAMP
miR
CD20/MS4A1 蛋白, Cynomolgus (HEK293, His)
c
The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling PMID 16880529
Determination of SCH 211803 by nanoelectrospray infusion mass spectrometry evaluation of matrix effect and comparison with liquid chromatography
Redox
Thiram
Nine pairs of megastigmane enantiomers from the leaves of Eucommia ulmoides Oliver PMID 28634927
Herpetotriol 89020
Induction of transglutaminase 2 by a liver X receptor/retinoic acid receptor alpha pathway increases the clearance of apoptotic cells by human macrophages PMID 19628791
MS8815N 2855085
A concise synthesis of ginkgolide M, a minor component of a terpene trilactone fraction from ginkgo biloba roots PMID 16562852
m
Pristanic acid
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3
1,4
Amosulalol hydrochloride 70958
Epoxygenase pathways of arachidonic acid metabolism PMID 11451964
NU
4
YTHDF3
(21S)
Aminopyralid soil residues affect rotational vegetable crops in Florida PMID 21413141
Saframycin F 92569
Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers PMID 16533838
NANOG regulate the JAK/STAT3 pathway to promote trophoblast cell migration and epithelial
NU1003
ZIF 90
Epithelial cells activate fibroblasts to promote esophageal cancer development PMID 36963399
Vibrational analysis of 1,4
BTS44596 139542
LasB
Twist1
Triggering of Suicidal Erythrocyte Death by the Antibiotic Ionophore Nigericin PMID 26458067
(S)
BMS
DBCO
Aplysin 6790
3,5
SLM6 22242
Oxymatrine alleviated hepatic lipid metabolism via regulating miR
Glycine transporter 1 is a target for the treatment of epilepsy PMID 26302655
5,5'
B7
Discovery of oxazoline enhancers of cellular progranulin release PMID 36368496
Calindol hydrochloride 729610
2
Pacrinolol (HOE 224)
Compounds targeting OSBPL7 increase ABCA1
Mask protein keeps NF
MCE
USP14
Orosomucoid proteins limit endoplasmic reticulum stress in plants PMID 37606093
Targeting RIPK1
BA38017 1333905
HA1/Hemagglutinin 蛋白, H5N1 (ABG67978, HEK293, His)
JAML inhibits colorectal carcinogenesis by modulating the tumor immune microenvironment PMID 38625487
5,10,15,20
Olevaprubart
Synthesis and cytotoxicity of 8
Prexasertib Mesylate Hydrate 1234015
Design, synthesis and anticancer potential of NSC
Leukotriene B(4) receptors BLT1 and BLT2 are involved in interleukin
Novel Method for Preparation of Site
meso
(4
Environmentally Relevant Dose of Bisphenol A Does Not Affect Lipid Metabolism and Has No Synergetic or Antagonistic Effects on Genistein's Beneficial Roles on Lipid Metabolism PMID 27171397
CD105/Endoglin 蛋白, Human (HEK293, His)
PH
Coronavirus endoribonuclease antagonizes ZBP1
Indolelactic acid
Control of fibrosis and hypertrophic scar formation via glycolysis regulation with IR780 PMID 35769829
Intrathecal Tyr
Fmoc
Novel Silicon
5
PI3K inhibitor 3
Mitophagy induced by UMI
Afferent arteriolar vasodilator effect of adenosine predominantly involves adenosine A2B receptor activation PMID 20462966
溶质载体家族 2 成员 14（SLC2A14）基因
Directed evolution of a family of AAV capsid variants enabling potent muscle
2'
BAY
Cyclopamine
Ombetoxabart
[Single dose toxicity studies of metabolite, degradation product and impurity of montirelin hydrate (NS
Tyrosine kinase
Antimicrobial activity of Coniothyrium minitans and its macrolide antibiotic macrosphelide A PMID 19298513
Punicalagin is a neuraminidase inhibitor of influenza viruses PMID 32827314
Enoxacin
Antidepressant, anxiogenic, and antinociceptive properties of levofloxacin in rats and mice PMID 11325396
OnclncRNA
Role of human liver microsomes in in vitro metabolism of drugs
4
Empagliflozin Alleviates Atherosclerosis Progression by Inhibiting Inflammation and Sympathetic Activity in a Normoglycemic Mouse Model PMID 34103961
Ampelopsin suppresses breast carcinogenesis by inhibiting the mTOR signalling pathway PMID 24861637
Ethyl nonadecanoate 18281
Loss of Lipocalin2 confers cisplatin vulnerability through modulating NF
Adipocyte lipolysis
Target complement factor H / serum amyloid a signaling in trichloroethylene
Pneumonectomy combined with SU5416 induces severe pulmonary hypertension in rats PMID 27036867
Dioctyl Terepthalate
3,4
Influenza A Virus Induces Autophagosome by Inhibiting LTCC/Calpain 2/LC3A Signaling to Promote Viral Replication PMID 40358023
NLRP3 modulator 8 3069891
Roniciclib 1223498
Antithrombotic and antiallergic activities of rhaponticin from Rhei Rhizoma are activated by human intestinal bacteria PMID 12214867
Antinociceptive and anti
MCE
Trijugin A 1233534
4,4',4'',4'''
CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase PMID 25661920
Metconazole 125116
Involvement of allopregnanolone in the anti
Hepcidin antagonist
PLLA3000
GLP
PI3K
CD94 蛋白, Human (HEK293, His
Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma PMID 34899687
Bilogical and toxicological properties of econazole, a broad
cis
Enciprazine dihydrochloride
LNA
CXADR
Nonaethylene glycol 3386
base oxidation
4
The multifaceted roles of the matrikine Pro
Glyco
4,2′ 4′,4′′
TNFRSF receptor
Aldastotug 2865844
RNAi
Downregulating Long Non
CXCL13
SIRT1 inhibits gastric cancer proliferation and metastasis via STAT3/MMP
PPP1R15A Promotes Apoptosis, Autophagy, and Inflammatory Response to Exacerbate Ischemic Stroke Through Activation of TLR4/NF
(1,2
Antiviral effects of selected IMPDH and DHODH inhibitors against foot and mouth disease virus PMID 31545264
Diverse targets of SMN2
BiFC and FACS
Ethacrynic acid increases facility of outflow in the human eye in vitro PMID 1731701
Epitope Molecularly Imprinted Polymer Nanoparticles for Chemo
Selective Wee1 degradation by PROTAC degraders recruiting VHL and CRBN E3 ubiquitin ligases PMID 35231578
Methyl protodioscin increases ABCA1 expression and cholesterol efflux while inhibiting gene expressions for synthesis of cholesterol and triglycerides by suppressing SREBP transcription and microRNA 33a/b levels PMID 25733328
2
Discovery of novel AKT inhibitors with enhanced anti
4,4'
COG1410 regulates microglial states and protects retinal ganglion cells in retinal ischemia
Iron
ADRA2A
Design and synthesis of 2
Design, Synthesis, and Biological Evaluation for First GPX4 and CDK Dual Inhibitors PMID 38295524
5',5''''
Preclinical characterization of ABT
MCE
Synthesis and biological evaluation of gold(III) Schiff base complexes for the treatment of hepatocellular carcinoma through attenuating TrxR activity PMID 32213395
New insights into the molecular and cellular functions of poly(ADP
Demeton
DBIBB 1569309
High
astrointestinal system
Soyasaponin II protects against acute liver failure through diminishing YB
Humanized anti
Novel Dual Mechanism GRT
The gentamicin antibiotics. 6. Gentamicin C2b, an aminoglycoside antibiotic produced by Micromonospora purpurea mutant JI
Discovery of a Promising Fluorine
Talsupram hydrochloride 25487
The anti
The immunotherapy mechanism of Hedyotis Diffusae Herba in treating liver cancer a study based on network pharmacology, bioinformatics, and experimental validation PMID 39093467
Versatile O
3,6
小核核糖核蛋白 U5 亚基 200（SNRNP200）基因
5
α
IL
2
Elevating acetyl
Design, synthesis, and biological evaluation of C
Protozoan
Effects of TU
6,6',6",6"'
mmu
Design, synthesis and in vitro cell
FKN secreted by kidney epithelial cells regulates macrophage activation in lupus nephritis via the Hippo signaling pathway PMID 37751892
SARS
Discovery of Gemilukast (ONO
Extratubular Polymerized Uromodulin Induces Leukocyte Recruitment and Inflammation In Vivo PMID 33414784
Max Dimerization Protein 3 抗体 (YA2229)（Max Dimerization Protein 3 Antibody (YA2229)）
Design, synthesis, structure
Nphs1
WD repeat and SOCS box containing protein 2 in the proliferation, cycle progression, and migration of melanoma cells PMID 31103822
Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation PMID 32208222
D
Homo
CLDN4 promotes ferroptosis and inflammation involving JAK2/STAT3 pathway in acute pancreatitis PMID 40892111
Fexapotide 492447
Immunity
ELMOD3
Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists binding to a common chemokine receptor motif within the helical bundle PMID 10770925
Apelin
ABT
rno
New Spisulosine Derivative promotes robust autophagic response to cancer cells PMID 31926468
CRBN ligand
Creatine deficiency syndrome. A treatable myopathy due to arginine
Application of a Novel Method for Measuring Carbadox Residues in Retail Pork PMID 40968650
ERK5 is activated by oncogenic BRAF and promotes melanoma growth PMID 29483645
IL
Silencing THBS1 in M2 Macrophages Exerts an Inhibitory Effect on Tongue Squamous Cell Carcinoma by Suppressing TGF
In Vitro Activity of Isavuconazole against Rasamsonia Species PMID 27527087
CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage PMID 32496651
IRAK
Five alternative Helicobacter pylori antibiotics to counter high levofloxacin and metronidazole resistance in the Dominican Republic PMID 30917150
IRGM/Irgm1 facilitates macrophage apoptosis through ROS generation and MAPK signal transduction Irgm1+/
3D printed GelMA/HAMA based mechanical microenvironment boosted PDAC chemoresistance via NRF2
Antiopioid properties of the TYR
UT
Ecological risk assessment of atrazine in North American surface waters PMID 23147529
Phenylmethyl bromide
Impaired T cell
Small
Interleukin
Hesperetin Protects from Palmitic
Novel fluorinated derivatives of the broad
KSP inhibitor ARRY
Synthesis and evaluation of methoxyquinazoline sulfonamide derivatives as bifunctional molecular targeting tumor related inflammation and anti
Rapamycin has paradoxical effects on S6 phosphorylation in rats with and without seizures PMID 23145776
Dectin
Dietary supplementation of polysaccharides from Millettia speciosa Champ. ex Benth on growth performance, immune function, antioxidant abilities and intestinal health of Wenchang chickens PMID 40702452
LILRB1/CD85j/ILT2 蛋白, Human (Biotinylated, HEK293, Fc
白细胞介素 17B（IL17B）基因
CRISPR/Cas9
Saponin from Periploca forrestii Schltr Mitigates Oxazolone
Heat Shock Proteins as Immunomodulants PMID 30388847
Icariin protects against acute graft
ZM 213689 124190
Exposure to coal dust exacerbates cognitive impairment by activating the IL6/ERK1/2/SP1 signaling pathway PMID 38925396
Semisynthesis and antitumoral activity of 2
AMG 837 a potent, orally bioavailable GPR40 agonist PMID 22217876
Interleukin 13 and serotonin linking the immune and endocrine systems in murine models of intestinal inflammation PMID 24015275
Engineering plasmid copy number heterogeneity for dynamic microbial adaptation PMID 38890490
Identification of a novel farnesoid X receptor agonist, kaempferol
DL
Endothelin 1 (swine, human) TFA 394693
Modulators of Alpha
1
Valnivudine hydrochloride 956483
白细胞介素 1 受体辅助蛋白（IL1RAP）基因
Transcriptomic and bioinformatics analysis of the mechanism by which erythropoietin promotes recovery from traumatic brain injury in mice PMID 37488864
NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice PMID 37553374
Costunolide Plays an Anti
Modelling glioma invasion using 3D bioprinting and scaffold
LncRNA MIR210HG Facilitates Non
CD98 蛋白, Mouse (HEK293, His)
Long non
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis PMID 36649377
鸟苷酸环化酶 1 可溶性亚基 alpha 2（GUCY1A2）基因
Digestive enzyme inhibitors from grains as potential components of nutraceuticals PMID 22878393
GSK
1,2
PLXNB3 Human Pre
Discovery of selective inhibitors against EBNA1 via high throughput in silico virtual screening PMID 20405039
Uba52 Mouse Pre
Polygalatenoside A 914111
Abrogation of histone deacetylases (HDACs) decreases survival of chronic myeloid leukemia cells New insight into attenuating effects of the PI3K/c
Considerations for the Design of Antibody
1,1
UTSA
Methyl 2,3,4
Human neuronal transglutaminase (Neuronal Transglutaminase，人神经元转谷氨酰胺酶)
3,4,9,10
SIRP alpha V2/CD172a 蛋白, Human (HEK293, His)
ML355 1532593
TMEM173 蛋白, Human (Sumo
Factor XI
The effects of lauryl maltoside on the reactivation of several enzymes after treatment with guanidinium chloride PMID 3382670
Pharmacokinetics and pharmacodynamics of the cytolytic anti
Bioorthogonal SERS
ANA
Avasimibe inhibits the proliferation, migration and invasion of glioma cells by suppressing linc00339 PMID 32682982
Glycogen synthase kinase
Metabolic Reprogramming in the Heart and Lung in a Murine Model of Pulmonary Arterial Hypertension PMID 30159317
Discovery of 2
miR
Structure
A microbiota
Ephrin
Transcriptomic, Biochemical, and Morphological Study Reveals the Mechanism of Inhibition of Pseudopestalotiopsis camelliae
Adipocytes promote pancreatic cancer migration and invasion through fatty acid metabolic reprogramming PMID 37264956
Role of the paraventricular nucleus microenvironment in stress integration PMID 12193178
P4ha3 Mouse Pre
Iriflophenone
Igsf11
Origin and evolution of the Trk family of neurotrophic receptors PMID 16253518
CRBN ligand
Cytotoxic activity of 6
The specificities of protein kinase inhibitors an update PMID 12534346
IKBKE Human Pre
GSK319347A 862812
The isolation and characterization of β
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia
Acetate dependence of tumors PMID 25525877
The human hypothalamus a morpho
Effects of Metformin on the virus/host cell crosstalk in human papillomavirus
Review of anticancer activity of monoterpenoids Geraniol, nerol, geranial and neral PMID 35661738
Biochemical and Functional Characterization of the Trace Amine
Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants PMID 29414842
Aloperine protects the testis against testicular ischemia/reperfusion injury in rats PMID 39253755
(
Selective androgen receptor degrader (SARD) to overcome antiandrogen resistance in castration
DSP
New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor
Calcium sensitization of smooth muscle mediated by a Rho
Discovery of DS
AzddMeC (Standard)
Human glucose
A condensates
KAT6A 抗体 (YA6622)（KAT6A Antibody (YA6622)）
Alafosfalin, a new inhibitor of cell wall biosynthesis in vitro activity against urinary isolates in Japan and potentiation with beta
Erichrome blue black B 3564
Methyl 10(R),11(R)
Micheliolide inhibits LPS
ICOSLG
L
Trisubstituted barbiturates and thiobarbiturates Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti
Machine learning
A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC PMID 26175415
Phospholipase C is required for glucose
Myeloid
GABAA receptor agent 2 TFA 1781880
(+)
SMI
Swertiamarin a lead from Enicostemma littorale Blume. for anti
gp120
VB
Sphynolactone
Exogenous IGF
Dexamethasone metasulfobenzoate sodium 3936
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis PMID 37134161
Mal
The role of intercellular junction proteins in the penetration resistance of Drosophila larvae to avermectin PMID 36717043
Kinetic characterization of hydrolysis of nitrocefin, cefoxitin, and meropenem by β
1,3,5
Methyl orsellinate 3187
Baohuoside V 118544
Mechanism
Desthiobiotin
Mesembrine 468
Low concentrations of the stable prostaglandin endoperoxide U44069 stimulate shape change in quin2
Avenanthramide
miR
MCE
Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure
Thrazarine 120128
tris(N
Ligustilide attenuates nitric oxide
2,6
4
Kaempferol Plays a Neuroprotection Role by Alleviating Oxidative Stress via AKT/Nrf2/HO
Polyhydroxysteroidal glycosides from the starfish Anthenea chinensis PMID 20184290
4
B2M
Blocking the ATR
LMK
eIF2alpha phosphorylation bidirectionally regulates the switch from short
Structural snapshots of human pre
GNE
Discovery of arylamide
5,5'
Oxalic acid (cobalt) 814
2
MCE
Pax6
CGP 57380 (Standard)
ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia
Clorgyline hydrochloride 17780
Bis(2
SBI
Benzene
TAT
9,10
Targeting IL
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus PMID 16222292
Thrombin/PAR
Tiagabine
Apremilast
Rhinovirus activates interleukin
Acutissimalignan B 1005390
4
Effects of oxidative stress on hepatic encephalopathy pathogenesis in mice PMID 37488119
Ropivacaine suppresses tumor biological characteristics of human hepatocellular carcinoma via inhibiting IGF
Iron azobenzene tetracarboxylic 1257379
Abacavir a review of its clinical potential in patients with HIV infection PMID 10983741
MCE
A microtubule
Angiotensin
4
Metastasis
Dopamine β
IGFBP
Pracinostat inhibits the nefarious biological behavior of pancreatic cancer by targeting the miR
D
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