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Evocarpine 15266
Intravesical instillation of c
2,6
Cytotoxicity and genotoxicity of 1,4
4,4'
Generation of cytotoxic T
Regulations of expressions of rat/human sulfotransferases by anticancer drug, nolatrexed, and micronutrients PMID 34387600
Structural basis for dual inhibitory role of tamarind Kunitz inhibitor (TKI) against factor Xa and trypsin PMID 23094997
Tetranitroblue tetrazolium chloride 1184
Redox status and metabolomic profiling of thioredoxin reductase inhibitors and 4 kGy ionizing radiation
Structure
Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma PMID 33139544
I
Biological activity of 3
Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease PMID 15540952
液泡蛋白分选 36 同系物（VPS36）基因
Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta
Effects of 13
Protocol for the differentiation of human alveolar epithelial type I cells from pluripotent stem cell
ABCE1 的 LTO1 成熟因子（LTO1）基因
Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS PMID 30205046
New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action PMID 9031665
(S,R,S)
Roles of necroptosis and autophagy in a mouse model of sepsis
The association between PI3K, JAK/STAT pathways with the PDL
Platelets upregulate tumor programmed death
The Discovery of Novel Selective D1 Dopaminergic Agonists A
CGP 56999 153994
Structure
Direct Quantification of Damaged Nucleotides in Oligonucleotides Using an Aerolysin Single Molecule Interface PMID 31989027
C
Preclinical studies of TW
Discovery and optimization of a series of 3
16
AGE
L
MCE
Cycloartane triterpenoids and their glycosides from the rhizomes of Cimicifuga foetida PMID 25136911
Designing of a bispecific antibody against SARS
In vivo antitumor activity of S 16020
hsa
Urea inhibits inducible nitric oxide synthase in macrophage cell line PMID 9435493
Fragment
(
Discovery of a mutant
Effects of Four Compounds from Gentianella acuta (Michx.) Hulten on Hydrogen Peroxide
A small molecule inhibitor of ubiquitin
Inhibition of STAT3
13
Low
Spectroscopic demonstration of an initial stage of the complex of D
[1,1'
Helicobacter pylori enhances HLA
Biochemical characterization and in vitro activity of AZ513, a noncovalent, reversible, and noncompetitive inhibitor of fatty acid amide hydrolase PMID 21645511
The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS
Antioxidant and antiapoptotic activities of idoxifene and estradiol in hepatic fibrosis in rats PMID 14659978
IFRD1 Human Pre
Discovery of 4
Anticancer agent 186 2408740
Effect of the NK(3) receptor antagonist, talnetant, on rectal sensory function and compliance in healthy humans PMID 17727393
Alpelisib hydrochloride 1584128
FXR/HSD17B13 modulator 1 3067566
UTA1inh
4,6
Establishment and characterization study of ovine mammary organoids PMID 40108665
JW 618
PROTAC
Upregulation of HMGB1 promotes vascular dysfunction in the soft palate of patients with obstructive sleep apnea via the TLR4/NF
A Target Class Ligandability Evaluation of WD40 Repeat
ATTO 680 NHS ester 1537182
Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases PMID 19469544
5'
The class A repeats of Lrp5 are required for normal development of bone, retinal vasculature, and mammary gland in vivo PMID 40932232
The L
IDO
MCE
Zuclomiphene
Downregulation of RSAD2 ameliorates keratinocyte hyperproliferation and skin inflammation in psoriasis via the TAK1/NF
CD36
含高尔基体相关，伽马适应蛋白耳，ARF 结合蛋白 1（GGA1）基因
Boc
Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease PMID 21817129
Luffariellolide 111149
First
MCE
Functional effects of caloxin 1c2, a novel engineered selective inhibitor of plasma membrane Ca(2+)
1,3
CCK1 and CCK2 receptors regulate gastric pepsinogen secretion PMID 10408253
Excitotoxicity
Development and characterization of a novel anti
2
Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide
1,3
Geraniin Alleviates Mouse Laser
DL
Are 5'
Metoprolol
MCE
BCR ABL1
Parathyroid Hormone Receptor 1 抗体 (YA1452)（Parathyroid Hormone Receptor 1 Antibody (YA1452)）
Tripterygium glycoside fraction n2 ameliorates adriamycin
RNA 聚合酶 II 的延伸因子（ELL）基因
Magnetically Integrated Tumor
6
Antibodies directed against merozoite surface protein
Sul
Digital pathology with artificial intelligence analysis provides insight to the efficacy of anti
3
Tnfrsf12a
Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells PMID 30184252
5,5'
Abanoquil (Standard)
2,4
Optimization of an Hsp90β
Autoprocessing and oxyanion loop reorganization upon GC373 and nirmatrelvir binding of monomeric SARS
Design, synthesis, and testing of difluoroboron
Functional Redundancy of Linuron Degradation in Microbial Communities in Agricultural Soil and Biopurification Systems PMID 26944844
A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects PMID 12586843
Rat
NRP1 antagonist 2 483289
Bis
N
Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model PMID 34542998
Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease PMID 40619121
AT 1001 1314801
MCE
Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters PMID 9669506
Guajadial reverses multidrug resistance by inhibiting ABC transporter expression and suppressing the PI3K/Akt pathway in drug
Enmein
5
Skimmianine Modulates Tumor Proliferation and Immune Dynamics in Breast Cancer by Targeting PCNA and TNF
Shaping Rolling Circle Amplification Products into DNA Nanoparticles by Incorporation of Modified Nucleotides and Their Application to In Vitro and In Vivo Delivery of a Photosensitizer PMID 30041480
Camphor
Guggulsterone for Chemoprevention of Cancer PMID 26561056
Small
MCE
A53T α
Exploring the mechanism underlying the therapeutic effects of butein in colorectal cancer using network pharmacology and single
Clofutriben 1204178
Dynamic shape
5'
PRIMA
MAGL
Benzbromarone mitigates cisplatin nephrotoxicity involving enhanced peroxisome proliferator
Astragaloside IV
Antitumour effects of tetrazanbigen against human hepatocellular carcinoma QGY
Ondelopran 676501
Selective estrogen receptor degraders with novel structural motifs induce regression in a tamoxifen
The cyclophilin
Novel autophagy inducers lentztrehaloses A, B and C PMID 25757606
Aroma precursors of cigars from different tobacco parts and origins, and their correlations with sensory characteristics PMID 38192690
SAR7334 hydrochloride 1333207
MCE
Anti
Lignans in resin of Araucaria angustifolia by gas chromatography/mass spectrometry PMID 15532064
DuP 714 130982
Pyruvate Kinase M2 Promotes the Activation of Dendritic Cells by Enhancing IL
Dual
Anti
R
Identification of the pre
A novel class of selective CK2 inhibitors targeting its open hinge conformation PMID 32283296
Circulating Neutrophils Predict Poor Survival for HCC and Promote HCC Progression Through p53 and STAT3 Signaling Pathway PMID 32328178
Ganetespib (STA
Beta
MCE
趋化因子 (C
Caspase
Prevention of pain on injection of rocuronium a comparison of lidocaine with different doses of parecoxib PMID 22762978
PVA (Mw 27000, 98
An expeditious synthesis of tamoxifen, a representative SERM (selective estrogen receptor modulator), via the three
1,1'
Evaluation of Double Self
The discovery of avanafil for the treatment of erectile dysfunction a novel pyrimidine
Delavirdine 136817
Synthesis and biological evaluation of some novel 1,2,3
Discovery and development of clofarabine a nucleoside analogue for treating cancer PMID 17016426
Endothelial CD38
FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway PMID 34608500
(3R,5R)
Effect of inhibiting ACAT
Antidepressant
Deltasonamide 1 2088485
MicroRNA
Pyrroline
Synthesis and use of a novel biotinylated probe for the chemiluminescent detection of proteins that bind 15
IRMOF
Relation of triiodothyronine and reverse triiodothyronine administration in rats to hepatic L
Preparation of Novel PARP1 Inhibitors and Their Use in Cancer Treatment PMID 40832518
Antiaversive effects of 5HT2C receptor agonists and fluoxetine in a model of panic
Discovery of a Small Molecule Probe That Post
Natural Product Bis
Lack of correlation between in vitro inhibition of CYP3A
Cadherin
Tenatoprazole sodium 335299
Odapipam 131796
Topoisomerase II inhibitor 7 2697171
S
Alnusdiol 56973
Effects on DNA repair in human lymphocytes exposed to the food dye tartrazine yellow PMID 25750299
Simultaneous quantification of lenalidomide, ibrutinib and its active metabolite PCI
HA/Hemagglutinin 蛋白, H1N1 (ACQ89903,sf9, His)
Immediate effects of 14 non MAOI antidepressants in rats with spontaneous petit mal
Exosomal Wnt
Genistein, daidzein and glycitein inhibit growth and DNA synthesis of aortic smooth muscle cells from stroke
The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro PMID 17438047
Specific targets for antiviral drugs PMID 6181775
Azido
Suberoyl bis
Guancydine 1113
Effect of chloride on renin and blood pressure responses to sodium chloride PMID 6303178
Acetamiprid
Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)
Omadacycline Efficacy against Enterococcus faecalis Isolated in China In Vitro Activity, Heteroresistance, and Resistance Mechanisms PMID 31871086
Small
Discovery of phenylselenoether
钙电压门控通道亚基 alpha1 B（CACNA1B）基因
PKR Inhibitor, negative control 852547
2
Encapsulation of TiO2 nanoparticles with poly(4
Evaluation of an automated chromogenic substrate assay for the rapid determination of hirudin in plasma PMID 7740508
Ascorbate oxidase is the potential conductor of a symphony of signaling pathways PMID 23299329
9
Multiple Resistance of Botrytis cinerea from Vegetable Crops to Carbendazim, Diethofencarb, Procymidone, and Pyrimethanil in China PMID 30754466
A Small
MitoPeDPP 1187472
Hinokitiol
Flow cytometric identification of microorganisms by dual staining with FITC and PI PMID 1696535
Eftilagimod alpha, a soluble lymphocyte activation gene
Increase of autophagy and attenuation of apoptosis by Salvigenin promote survival of SH
Effects of chronic, urea
Simple Enzymatic Incorporation of 2'OMeU Nucleotide at the End of the Poly
2
1,1
Anti
Discovery, Synthesis, and Activity Evaluation of Novel Five
Dexamethasone
A Warhead Substitution Study on the Coronavirus Main Protease Inhibitor Nirmatrelvir PMID 35971455
Microbioreactor array screening of Wnt modulators and microenvironmental factors in osteogenic differentiation of mesenchymal progenitor cells PMID 24376608
USP7 promotes cardiometabolic disorders and mitochondrial homeostasis dysfunction in diabetic mice via stabilizing PGC1β PMID 38815879
Steroids from Harrisonia abyssinica PMID 10705738
CRBN ligand
Maxadilan 135374
The overview of Mitogen
A role for exosomes in the constitutive and stimulus
MIF 蛋白, Human (HEK293, His)
Tetrahydroxy Stilbene Glucoside Alleviates Ischemic Stroke by Regulating Conformation
Pimecrolimus impurity 4 1025113
Retinyl acetate
CCDC134 ameliorated experimental autoimmune encephalomyelitis by suppressing Th1 and Th17 cells PMID 29548993
MK
PSB
Design and synthesis of 3
Thalidomide
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps PMID 30143555
SAG dihydrochloride 2702366
Bromodomain inhibitors and cancer therapy From structures to applications PMID 27911230
Anti gram
ILC2
Valeryl salicylate 64206
SC
CRBN ligand
Thionin acetate 78338
Ailanthoidol 156398
eIF3d controls the persistent integrated stress response PMID 37683648
Glyceryl Triformate 32765
PPFIA 结合蛋白 2（PPFIBP2）基因
Androgen receptor ligand 4
1
Luvometinib 2739690
(±)5
Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling PMID 27556948
Mechanistic exploration of hexokinase 2 and metabolism in diabetic cardiomyopathy PMID 40417885
Tanshinones from Salvia miltiorrhiza inhibit Mycobacterium tuberculosis via disruption of the cell envelope surface and oxidative stress PMID 34273428
Amrecibart 3008610
Liver X receptors and skeleton Current state
Cholesterol asymmetry at the tip of filopodia during cell adhesion PMID 32162745
5,5',5''
The methylation of adenylyl
Diarylureas are small
Alkoxyalkyl esters of 9
Blocking activator protein
Perillic acid 7694
Budiodarone tartrate 478941
4
PHCCC(4Me) 1259532
Pharmacokinetics of felbinac after intravenous administration of felbinac trometamol in rats PMID 21182394
Discovery of a novel series of biphenyl benzoic acid derivatives as highly potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. Part II PMID 18553954
CRBN ligand
Dabequin phosphate 56548
Synthesis and structure
Gas
Naphthol AS
S
Corydine 476
Ethyl heptadecanoate 14010
An Edaravone
Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity PMID 35867655
Estrone
m
2
The nonpeptide angiotensin
Intestinal Klebsiella pneumoniae infection enhances susceptibility to epileptic seizure which can be reduced by microglia activation PMID 34234109
Pharmacological promotion of inclusion formation a therapeutic approach for Huntington's and Parkinson's diseases PMID 16537516
Leucomethylene blue mesylate 1236208
Effect of Hypotensive Drugs on Dynamics of Nitroxide
Efficacy of an agonist of α
A simple and robust cell
VU0240382 1092550
Enhanced antimalarial activity by a novel artemether
Aurkin
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway PMID 30995036
Bronchodilatory and anti
PD 109488 103733
SCH 51344 171927
MCE
LEB
Ganodermatriol 105300
Isodienestrol 35495
Pyributicarb 88678
Derivatives of Dictyostelium differentiation
S
A new homoisoflavan from Caesalpinia sappan PMID 18404306
Melagatran 159776
Naphthalene
Minocycline
ISR modulator
MCE
N
Microglia regulate cortical remyelination via TNFR1
Nonyl 10
The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells PMID 36170818
A Curcumin Analog Exhibits Multiple Biologic Effects on the Pathogenesis of Alzheimer's Disease and Improves Behavior, Inflammation, and β
Sertaconazole nitrate 99592
Procurcumenol 21698
Fudecalone 162341
CD59 蛋白, Rat (HEK293, His)
含锌指 MYND 型 10（ZMYND10）基因
ZCZ011 1998197
Litmus 1393
2
5
Aldecalmycin, a new antimicrobial antibiotic from Streptomyces PMID 1548185
[1,1 4,1
YS
Rational Design, Synthesis, and Biological Evaluation of Novel c
LAS17 2362527
Design, synthesis and structure
AZ'6421 2361115
The treatment of inflammatory facial dermatoses with topical corticosteroids focus on clocortolone pivalate 0.1% cream PMID 23134984
1
The Wnt pathway protein Dvl1 targets Somatostatin receptor 2 for lysosome
In vitro study of CI
Design and synthesis of novel sulfur
Cortisone dissociates the Shaker family K+ channels from their beta subunits PMID 18806782
FBXW5 acts as a negative regulator of pathological cardiac hypertrophy by decreasing the TAK1 signaling to pro
Tectorigenin 548
trans
[Perindopril in the treatment of hypertension and cardiovascular diseases evolution continues with the orodispersible dosage form] PMID 23711055
CRBN ligand
WAY
(R)
(±)
Enhancement of synthetic lethality via combinations of ABT
ARN14494 1037837
Integration of Zebrafish Model and Network Pharmacology to Explore Possible Action Mechanisms of Morinda officinalis for Treating Osteoporosis PMID 32190963
N
Indolealkylamine analogs share 5
MCE
SARS
含 pleckstrin 同源结构域 A5（PLEKHA5）基因
The Effect of Salts on the CO2 Reduction Product Distribution in an Aprotic Electrolyte PMID 39234782
Ansipastobart 2829250
hsa
CYP4A11/CYP4F2
FL442 1431166
Anti
Modelling the photochemistry of imazethapyr in rice paddy water PMID 30743851
Alkaloids in commercial preparations of California poppy
Selective and Potent PROTAC Degraders of c
Phenolphthalein bisphosphate sodium 68807
GPCR agonist
TP0628103 2865102
MT
HSD17B13
EST64454 a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management PMID 33237785
Tofogliflozin, a novel sodium
Contribution of membrane trafficking perturbation to retinal toxicity PMID 25771199
MCE
U
HL23 1448355
Comparison of antispasmodic effect of synthetic lysolecithins with various fatty acid moieties on guinea pig ileum PMID 6481614
Atesidorsen sodium 1826859
7
CRBN ligand
4,7,10,13,16
MCE
CRBN ligand
8
Phase I evaluation of STA
Anti
ORM
BMS
Pentadecanoyl
EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells PMID 22753156
Glucokinase activator 3 1001417
Tau protein (592
Molecular actions of (S)
2
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5
N
Design and synthesis of novel indole and indazole
Isolation, Structure Elucidation, and Bioactivity Evaluation of Two Alkaloids From Piper chaba H. Stem A Traditional Medicinal Spice and Its Chemico
MDAN
P
(Rac)
SIRT1 activator 3 839699
Amyloid β and tau are involved in sleep disorder in Alzheimer's disease by orexin A and adenosine A(1) receptor PMID 30365112
Investigation of Drug
Alisporivir 254435
Simultaneous inhibition of PFKFB3 and GLS1 selectively kills KRAS
93
5,5'
(S)
CDK2
4
Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa PMID 27120257
6
Palbociclib
Mupirocin lithium 73346
Discovery of the cereblon
Covalent narlaprevir
N
ALKBH5 exacerbates psoriatic dermatitis in mice by promoting angiogenesis PMID 40522618
Glutinyl acetate 6426
Oncrasin
N
(S)
Comparative effects of R 80122, enoximone, and milrinone on left ventricular phosphodiesterase isoenzymes in vitro and on contractility of normal and stunned myocardium in vivo in dogs PMID 1381769
An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus PMID 12852746
Ziprasidone hydrochloride 122883
Targeting the overexpressed USP7 inhibits esophageal squamous cell carcinoma cell growth by inducing NOXA
Vasopressin
Cyathin A3 38598
Metapramine 21730
Structure
ADTL
Wnt Signaling Regulates MFSD2A
4,4'
Ro 09
Flupirtine hydrochloride 33400
Dimethyl L
Velnacrine maleate 118909
SAR405 R enantiomer 1946010
Gartanin induces autophagy through JNK activation which extenuates caspase
Prevention of the expression of inducible nitric oxide synthase by a novel positive inotropic agent, YS 49, in rat vascular smooth muscle and RAW 264.7 macrophages PMID 10510445
Pyrimidin
Octyl thiomaltoside 148616
CBP/p300
Balsalazide
Further optimization of the K
Radiosynthesis and in vivo evaluation of a new positron emission tomography radiotracer targeting bromodomain and extra
Oxogestone phenpropionate 16915
KUC
MCE
Antioxidant treatment of experimental diabetic retinopathy in rats with nicanartine PMID 9222640
The selective estrogen receptor downregulator GDC
Identification of Isoliensinine as a Ferroptosis Suppressor with Iron
CARP
H
Vitisin A 142449
PAR2 modulator
DNP
MCE
PENK Human Pre
RAD51 旁系同源 B（RAD51B）基因
SHLP
Pralidoxime 6735
Logmalicid B 1638895
S100P 蛋白, Human (His, solution)
溶质载体家族 29 成员 1 (奥古斯丁血型)（SLC29A1）基因
Aurkin A 1534060
Bis(N,N'
Continuously recording fluorescent assays optimized for five human matrix metalloproteinases PMID 1888020
The fidelity of cancer cells in PDX models Characteristics, mechanism and clinical significance PMID 31479514
Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging PMID 17138819
Etazolate 51022
Chemical switch of a metabotropic glutamate receptor 2 silent allosteric modulator into dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulators PMID 21105727
m
(7R)
MAPK14 Human Pre
Binding Modes of Small
Cox6b1
HIV
(±)
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