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LncRNA MALAT1 potentiates autophagy‑associated cisplatin resistance by regulating the microRNA‑30b/autophagy‑related gene 5 axis in gastric cancer PMID 30365113
Evaluation of the effect of green tea and its constituents on embryo development in a zebrafish model PMID 35982029
Nivudirsen sodium
Live
Triptolide Inhibits Preformed Fibril
Repositioning of 8
Atiprimod induce apoptosis in pituitary adenoma Endoplasmic reticulum stress and autophagy pathways PMID 31270852
SLC46A1 蛋白, Human (HEK293, His, MBP, FLAG)
BMS
N6
2
Deubiquitination of RIPK2 by OTUB2 augments NOD2 signalling and protective effects in intestinal inflammation PMID 39358938
Insight into the Mechanism of Interactions between the LL
Relative efficacies of piperazines at the phosphoinositide hydrolysis
A logical network
CGA
Spirooxindole
Naluzotan hydrochloride 740873
2,3
Pivmecillinam 32886
5,5'
A Casz1
1,2
Ceramide d18 1/24 1 as a potential biomarker to differentiate obesity subtypes with unfavorable health outcomes PMID 37794463
Perfluorobutanesulfonic Acid Disrupts Pancreatic Organogenesis and Regulation of Lipid Metabolism in the Zebrafish, Danio rerio PMID 30239974
Inhibitory effects of salidroside and paeonol on tyrosinase activity and melanin synthesis in mouse B16F10 melanoma cells and ultraviolet B
Bexarotene 153559
Forkhead box protein A2 alleviates toll
A novel inhibitor of monooxygenase reversed the activity of tetracyclines against tet(X3)/tet(X4)
6,6'
2
Diethyl 2,5
PCN
1,1′
In vitro μ
5α
1,3
Di(pyrazin
3
5
Ethanol extract of Liriodendron tulipifera leaves displays anti
Identification of GRIN2D as a novel therapeutic target in pancreatic ductal adenocarcinoma PMID 37553583
Targeting CDK12 obviates the malignant phenotypes of colorectal cancer through the Wnt/β
Synthesis of xanthone derivatives based on α
GSK369796
Antiproliferative effect of the histone demethylase inhibitor GSK
Estrogenic activity of furanocoumarins isolated from Angelica dahurica PMID 17024846
1,1'
SMN
Lithium4
Triptolide
Sodium 1,3,5
2,3
1,3
2,4,6
4
Developing LC
4
4,4'
MCE
Discovery of Selective Small
Cisplatin
2
4,5
2,2'
1,4
Cariporide inhibits high glucose
Decahydro
N
1,2
4
2,5
2'
SB
Microwave hyperthermia enhances the sensitivity of lung cancer cells to gemcitabine through reactive oxygen species‑induced autophagic death PMID 30976815
[4,2' 5',4''
FPL64176 120934
1,3,6,8
5'
2,5
Design, synthesis, and evaluation of the antiproliferative activity of a series of novel fused xanthenone aminoderivatives in human breast cancer cells PMID 17335189
4,4'
5,10,15,20
RK
BH3 profiling discriminates on
7
1,3,5,9
MIF promotes Th17 cell differentiation in rheumatoid arthritis through ATF6 signal pathway PMID 39614150
Discovery of Potent and Selective Receptor
CRBN ligand
Identification of Direct
( )
Protocol to generate induced trophoblast stem cells from embryonic stem cells in mice PMID 36853659
Design, synthesis, and antitumor evaluation of morpholine substituted bisnaphthalimides as DNA targeting agents PMID 36894107
SLC25A19 蛋白, Human (Cell
(21S)
112714
SGC
Tumor
The membrane permeable calcium chelator BAPTA
CRBN ligand
1
Monophosphoryl lipid A free acid 960324
Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation PMID 23404625
TH1020 1841460
Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation PMID 22002558
Pericytes in castration
[1,1'
2
MWAC
Physical Encapsulation and Chemotherapy A Synergistic Hydrogel Strategy for Tumor Suppression PMID 40321022
5
BICC1 drives pancreatic cancer stemness and chemoresistance by facilitating tryptophan metabolism PMID 38896624
LGF308 3061406
6
A
Design, synthesis, biological evaluation and X
碳酸酐酶 13（CA13）基因
1,3,5
Monocarboxylic Acid Transporter 1 抗体 (YA3244)(PBS only)（Monocarboxylic Acid Transporter 1 Antibody (YA3244)(PBS only)）
The long non
Design, synthesis and bioactive evaluation of novel quinoline
Aluminum,hydroxy[1H
Acutumidine 18145
N,N'
Targeting the mevalonate or Wnt pathways to overcome CAR T
FICZ 172922
6RK73 1895050
PROTAC EGFR degrader 11 3034244
5′
Muricarpone B 886226
AZD
Exosomal SphK1 from colorectal cancer cells promotes cancer cell migration and activates hepatic stellate cells PMID 39930826
2,3,5,6
Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B PMID 34512150
Strictly regulated agonist
Antiviral agent 76 1612249
Bis
AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway
Rosiglitazone
IWP
SIFSIX
Kojic amine
Ferroptosis a new target for iron overload
1,3
Di(1H
3,3''
2
5,5'
Erythrina Cristagalli Lectin (ECL)
5,5'
MIL
Bis
2,5
4,4′,4′′,4′′′
Pyridin
4
2
Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes PMID 24059847
Valproic acid sodium (2 1) 76584
4,4',4'',4'''
5,5'
(2,7
SARS
5,5'
Prostate
The ARCCRABP1 neurons play a crucial role in the regulation of energy homeostasis PMID 40057489
Lurtotecan 149882
2,2,2
Harnessing cell cycle intervention and evading P
4,4'
1,1'
2,5
2,3,5,6
2'
1,3,5
5,5'
R 58639 99157
SLC30A8 蛋白, Mouse (Cell
2,5
Zinc(II) tetrakis(4
Improvement and biological applications of fluorescent probes for zinc, ZnAFs PMID 12047174
2
Talastine 16188
Design, Synthesis, and Structure
Comparison of the effects of peripherally administered kisspeptins PMID 18940206
Role of TLR4
Enhancement of antibody production against rabies virus by uridine 5'
Validation of chemical genetics for the study of zipper
Molecular mechanism of the tree shrew's insensitivity to spiciness PMID 30001322
IL28RA/IFNLR1 蛋白, Human (Biotinylated, HEK293, His
ALKBH5 promotes non
Yunnancoronarin B 162762
Chlorotoxin a helpful natural scorpion peptide to diagnose glioma and fight tumor invasion PMID 25826056
Multistage ROS
EP1013 223568
The isoquinoline sulfonamide inhibitors of protein phosphorylation, H
Anticancer agent 46 2426686
The metabolism of 20
Mitoflaxone 87626
4,4',4',4''
2,3,5,6
Diosmin alleviates colitis by inhibiting PANoptosis of intestinal epithelial cells and regulating gut microbiota and metabolites PMID 40138774
DL
m
CoREST Complex
ATG5
Rimiterol 32953
IAXO
A Nongenetic Proximity
CG001, a C3b
Dietary Suberic Acid Protects Against UVB
PLGA
PIN1‑silencing mitigates keratinocyte proliferation and the inflammatory response in psoriasis by activating mitochondrial autophagy PMID 39234585
N,N',N'
MKI
LncRNA LINC01128 promotes prostate cancer cell proliferation, metastasis, and epithelial
1,2
Selective beta 1
(S)
Sulfasymazine 1984
TIFSIX
SNAP25 Human Pre
HARS2 Human Pre
1,2,3,4
Bis(3,5
4,4′
5
1,3,5
(Z)
The dipeptidyl peptidase
6,13
4
Brexanolone caprilcerbate 2681264
1,2,4
Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo PMID 17215084
4,4'
[1,1' 4',1'' 4'',1'''
5,5'
(5
Copper(II)
Picoberin 3034663
Evaluation of the antimicrobial activities of plant oxylipins supports their involvement in defense against pathogens PMID 16299186
4',4''',4''''',4'''''''
Biphenyl
2
PKR activator 3 1628428
5,5'
4,4'
TRPV1 analgesics disturb core body temperature via a biased allosteric mechanism involving conformations distinct from that for nociception PMID 38492574
2
N1,N4
A rapid and versatile reverse genetic approach and visualization animal models for emerging zoonotic pseudorabies virus PMID 39522887
Discovery of sinomenine/8
Nonaethylene glycol
5
(D
Cell
5'
Potent bombesin
HA/Hemagglutinin 蛋白, H1N1 (ABW40422, HEK293, His)
Notoginsenoside Fa 88100
MLKL
USP2 Catalytic Domain 蛋白, Human (His)
Synthesis of the natural products 3
Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs PMID 30112821
Serum apolipoprotein A
Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro
NMR and DFT studies of the complexation of W(VI) and Mo(VI) with 3
Discovery of a series of 1,3,4
Upregulation of the oxytocin receptors on peripheral sensory neurons mediated analgesia in chemotherapy
1,3
Synergistic inhibition of lung cancer cells by EGCG and NF
Cold atmospheric plasma targets triple negative breast cancer cells via SCAF11
Cyclo(Pro
Adagrasib, a KRAS G12C inhibitor, reverses the multidrug resistance mediated by ABCB1 in vitro and in vivo PMID 36104708
Real
Physiological pH Transition
Palmitoyl coenzyme A lithium 188174
(S,R,S)
Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non
Taurine protected As2O3
TrkA 蛋白, Human (HEK293, mFc)
BL
PVR 细胞粘附分子（PVR）基因
HA/Hemagglutinin 蛋白, H2N2 (AAA43185, HEK293, His)
5,5'
hsa
5,5'
Chst5
Pestalotin 34565
Acute Methylmercury Exposure and the Hypoxia
Phytochemical and cytotoxic studies on the roots of Euphorbia fischeriana PMID 27913179
Differential effects between γ
Humulinone 981
4
Characterization of SB
Marein Prevented LPS
Carotol 465
Signaling between pancreatic β cells and macrophages via S100 calcium
Boc
TFPI inhibits breast cancer progression by suppressing ERK/p38 MAPK signaling pathway PMID 35567715
Therapeutic Effects of Human Urine
[4,4'
Novel avermectins produced by mutational biosynthesis PMID 2026561
Monorden B 88929
Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγ Agonist Activity and Anti
Effect of the selective kappa
Design, synthesis and biological evaluation of novel nitric oxide
4
Trehalose Alleviates Crystalline Silica
Cbl
MCE
Sodium3
1,4
2
((5
5
2
4,4'
Metabolite
SH
2,2
3,3',5,5'
4,4'
MIL
3,8
2,4,6
Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis PMID 20194690
2
Sarecycline hydrochloride for the treatment of acne vulgaris PMID 31720559
Sn(IV) meso
Hybridoma production by simplified avidin
5,5'
Cynomolgus Monkey serum albumin
4,4'
Pomalidomide
Effect of direct injection of melanin
1,6
MCE
5,10,15,20
6
Exosomal miR
Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta
[1,1′ 4′,1′′
HA/Hemagglutinin 蛋白, H1N1 (ACV49556, HEK293, His)
12
Increased cerebral endothelium
A careful look at lipid nanoparticle characterization analysis of benchmark formulations for encapsulation of RNA cargo size gradient PMID 38287070
MUC1‑ND interacts with TRPV1 to promote corneal epithelial cell proliferation in diabetic dry eye mice by partly activating the AKT signaling pathway PMID 39370807
beta
Tropomodulin1 exacerbates inflammatory response in macrophages by negatively regulating LPS
Investigation of Novel Quinoline
5'
EEF1A1 蛋白, Human (His
Carbuterol hydrochloride 34866
Gly
Complex effects of macrolide venturicidins on bacterial F
AJ
METTL3
Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor
3
Long noncoding RNA BMPR1B
Cyclohexane
Fmoc
4'
The antitumor activity of osimertinib plus palbociclib in non
M2 Macrophage
4
HLADP4
4
RNA binding protein ZCCHC24 promotes tumorigenicity in triple
6
5
Androgens alleviate the depression
3,3',5,5'
Pharmacokinetic features and metabolism of calphostin C, a naturally occurring perylenequinone with antileukemic activity PMID 10450923
UMCM
Co
Pycr1 Rat Pre
IFN
Inulin with a low degree of polymerization protects human umbilical vein endothelial cells from hypoxia/reoxygenation
Tris(perfluorophenyl)phosphine oxide
2,2'
Esculentoside F (商陆皂苷 F)
SR
Di(1H
2',5'
2
Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid
Depulfavirine 867365
Sclerostin Antibody Therapy for the Treatment of Osteoporosis Clinical Prospects and Challenges PMID 27313945
Design, synthesis, and biological evaluation of new thiazolo[5,4
1,3
4'
Kryptofix 221
Diphenic acid
Phenol, potassium salt (4 1)
1,1'
Dimethyl4,4'
1
4
Thalidomide
2
Synergistic optimizations of efficacy and membrane permeability of IRAK4 inhibitors identifying new lead compounds for anti
Ipilimumab 477202
Tetrahydrofolic acid trihydrochloride 150731
4,7
5
Benzene
MCE
Flumorph 211867
DPP
4
转录接头 3（TADA3）基因
Circular RNA hsa_circ_0102231 sponges miR
Poloxamer
Inhibition of Recombinant Human Acetylcholinesterase Activity by Antipsychotics PMID 31067549
Desfesoterodine 207679
CCT365623 2126134
New triterpenoids and PTP1B inhibitory constituents of Pseudolarix amabilis PMID 31705950
PBT 1033 hydrochloride 648896
Thalidomide
Pittsburgh Compound B 566169
EphB3 蛋白, Human (HEK293, His)
Clenbuterol
Small molecule 3PO inhibits glycolysis but does not bind to 6
Unraveling chain specific ubiquitination in cells using tandem ubiquitin binding entities PMID 40595035
Carbenoxolone inhibits Pannexin1 channels through interactions in the first extracellular loop PMID 26755773
LY
6,6',6',6''
(2,6
3,3′
Pharmacokinetics of cyproheptadine and its metabolites in rats PMID 8130779
pTH (7
Dabigatran ameliorates airway smooth muscle remodeling in asthma by modulating Yes
Resveratrol treatment delays growth plate fusion and improves bone growth in female rabbits PMID 23840780
Ala
Rutacridone 17948
A comprehensive overview of β
LY
Pentagalloylglucose Inhibits the Replication of Rabies Virus via Mediation of the miR
Daphnegiravone D 2581826
NO2
4,4'
4
Etv6
HK
Deficiency of CD93 exacerbates inflammation
MCE
3(S)
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway PMID 39924492
Promestriene 39219
2,2'
SC
RNA Interference Therapy Targeting Apolipoprotein C
1,1
4
1,1
Carboxyrhodamine 110
Use of mitogenic cascade blockers for treatment of C
Adrenaline in the treatment of anaphylaxis what is the evidence? PMID 14656845
CU(II) meso
Application of multiplexed kinase inhibitor beads to study kinome adaptations in drug
DSPE
Ppib Rat Pre
PTC258 2476724
Targeted protein degraders of SARS
Benzenesulfonate sodium (Standard)
Co
Isorhynchophylline protects against pulmonary arterial hypertension and suppresses PASMCs proliferation PMID 24950404
5
9,10
4,7
Bauhinia Purpurea Lectin (BPL)
GW 501516 317318
P
1,4
3,6
AF488 NHS ester 1374019
4,4'
4
Benzo[1,2
N
4,4''
Naphtho[2,1
5,5'
Detection of retinal dysfunction induced by HCN channel inhibitors using multistep light stimulus and long
Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors PMID 32551003
IRMOF
Hexabromobenzene
5
Exploration of the underlying mechanism of Astragaloside III in attenuating immunosuppression via network pharmacology and vitro/vivo pharmacological validation PMID 38648891
C
2
5,5',5''
Triphenylene
Topical minocycline formulations Evaluation and comparison of dermal uptake efficacy PMID 31517274
ZIF
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