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Fluorescence
MOF
Fructose aggravates copper
Mbip
AZD1152
Phosphoproteomic subtyping of gastric cancer reveals dynamic transformation with chemotherapy and guides targeted cancer treatment PMID 39357518
Adaptive changes in the kinetochore architecture facilitate proper spindle assembly PMID 26258631
Exploring the Natural Piericidins as Anti
[1,1' 4',1'' 4'',1'''
Age
4',4'''
UBA52 Human Pre
2,9
17β
Ubiquitin
Ladostigil, a novel multifunctional drug for the treatment of dementia co
6
AGR3 promotes estrogen receptor
Highly fluorescent and HDAC6 selective scriptaid analogues PMID 30448419
p38 Mitogen
Aprepitant Sensitizes Acute Myeloid Leukemia Cells to the Cytotoxic Effects of Cytosine Arabinoside in vitro and in vivo PMID 32606608
Appetite
Galectin 3
Cefpodoxime proxetil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential PMID 1280571
New taxane diterpenoids from the leaves and twigs of Taxus sumatrana PMID 12502326
Chemokine CCL28 induces apoptosis of decidual stromal cells via binding CCR3/CCR10 in human spontaneous abortion PMID 23737337
Molecular Mechanisms of Magnolol in Gastric Precancerous Lesions A Computational and Experimental Study PMID 39808163
All progestins are not created equal PMID 14667980
((2,4,6
2,6
HA/Hemagglutinin 蛋白, H1N1 (ABD62843, sf9, His)
Discovery of Nonquinone Substrates for NAD(P)H Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug
1,3
Mechanistic Insights into HOTAIR
2
1,3,5
Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy
[Cu2(bdc)2(bpe)]n
HSV
Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT) PMID 37024489
7
Polychlorinated Biphenyl Quinone Metabolites Cause Neutrophil Extracellular Traps in Mouse Bone Marrow Neutrophils PMID 35168318
Icariin Ameliorates Diabetic Cardiomyopathy Through Apelin/Sirt3 Signalling to Improve Mitochondrial Dysfunction PMID 32265695
Synthesis, cytotoxicity, and antiplasmodial and antitrypanosomal activity of new neocryptolepine derivatives PMID 12139461
USP21抑制剂、基因
Z
MCE
IL
Developmental endothelial locus
Celastrol inhibits mouse B16
Baicalein inhibits cell development, metastasis and EMT and induces apoptosis by regulating ERK signaling pathway in osteosarcoma PMID 31948366
Mn(III) meso
The elucidation of key factors for oral absorption enhancement of nanocrystal formulations In vitro
PRMT3 drives PD
PRMT5 蛋白, Human (HEK293, His
Conformationally restricted analogs of Combretastatin A
Signaling pathways underlying the antidepressant
COVID
Identification and characterization of O
Ginkgetin inhibits the proliferation and migration of lung cancer cells via FAK/STAT3/AKT pathway PMID 40366441
Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with in vivo activity by N
O
Asthma reduces glioma formation by T cell decorin
Acetyl
TET2
Single
Bafilomycin A1 inhibits SARS
Targeting nuclear β
Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction PMID 19695344
m
The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL
Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin
High
N3
SUZ12 Loss Amplifies the Ras/ERK Pathway by Activating Adenylate Cyclase 1 in NF1
Nickel(II) tetramethoxyphenylporphyrin (Nickel(II) tetramethoxyphenylporphyrin)
S100A9 induces nucleus pulposus cell degeneration through activation of the NF
Ccl28
Design, synthesis, and evaluation of novel benzofuran and pyrazole
Polymorphism of UDP
RUNDC3A Human Pre
Retaspimycin Hydrochloride 857402
PEBP1 suppresses HIV transcription and induces latency by inactivating MAPK/NF
5
Syntenin Controls Extracellular Vesicle
A Klotho
RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells PMID 35673573
Characteristics of splenic PD
Steroidal Saponins from the Rhizomes of Aspidistra typica PMID 26937954
4,4',4''
The inhibitor of phagocytosis, O
OG
ART615 3031765
Biperiden
CD79A 蛋白, Cynomolgus (HEK293, His)
HSPB1 Orchestrates the Inflammation
WDR72 Enhances the Stemness of Lung Cancer Cells by Activating the AKT/HIF
(E)
4
Ubiquitously specific protease 4 inhibitor
4
In Vivo Endothelial Cell Gene Silencing by siRNA
Diatrizoic acid
Iparomlimab and Tuvonralimab First Approval PMID 40167968
Beta
HY
Nimbolinin D
N,N′,N′′
Eda2r
BTS44596 (Prochloraz
HPLC/MS/MS quantitation method
Wnt Signalling in Acute Myeloid Leukaemia PMID 31703382
A tumor
RGT
The role and mechanism of PGC
Plasma concentrations of lysophosphatidic acid and the expression of its receptors in peripheral blood mononuclear cells are altered in patients with cocaine use disorders PMID 37344453
The Long Noncoding Transcript HNSCAT1 Activates KRT80 and Triggers Therapeutic Efficacy in Head and Neck Squamous Cell Carcinoma PMID 35965679
[Metabolism of 14C
NH
Anthracene
dimethyl 4,4'
Benzobis(imidazole) derivatives as STAT3 signal inhibitors with antitumor activity PMID 35504209
EGFR
4,4'
Dimethyl 5
Isoquinoline
Ethane
5,10,15,20
Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug
1,1'
Oprk1 Rat Pre
4,4'
meso
2, 3
2,6
2
3
Pzp
PCN
4,4',4''
4,4'
1,1'
2,5
(Z)
5,5'
KIR3DL3/CD158z 蛋白, Human (HEK293, Fc)
1,4
Bis(4
Pt(II) meso
Cys
5,5',5'',5'''
CS1 1448009
13,14
ALK2
MCE
MCE
5,5'
凝乳酶
3,3',3''
Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK/SIRT1/PGC
Single
5
N
Iron(III) mesotetraphenylporphine chloride
Therapeutic journery of nitrogen mustard as alkylating anticancer agents Historic to future perspectives PMID 29649739
1,3,5,7
2,5
2,5
SLC2A9 蛋白, Human (Cell
N
Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole
MCE
5,15
1,4
Fluindapyr 1383809
Actl6a
Screening for novel LRRK2 inhibitors using a high
MIL 125
Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment
Effect of Ampicillin on E. Coli of Swine Origin PMID 17649462
A novel network pharmacology approach for leukaemia differentiation therapy using Mogrify® PMID 36271030
Famciclovir. A review of its pharmacological properties and therapeutic efficacy in herpesvirus infections PMID 8521764
The isoquinoline derivative LOE 908 selectively blocks vasopressin
4
5,5'
EGFR
Toxoplasma gondii sustains survival by regulating cholesterol biosynthesis and uptake via SREBP2 activation PMID 39490926
1,2
Anti
Parishin A alleviates insomnia by regulating hypothalamic
Capsazepine Inhibits Astrocyte Activation and Attenuates Neuroinflammation by Targeting Syntaxin 7 PMID 40386937
Cordifolioside A 155179
Ptges2
Triterpenoids and steroids from the fruits of Melia toosendan and their cytotoxic effects on two human cancer cell lines PMID 20961091
meso
5
LINC00460 Promotes Cell Proliferation, Migration, Invasion, and Epithelial
3'
Farnesyl thiosalicylic acid amide (FTS amide)
DSS30 883027
Simultaneous analysis of regorafenib and sorafenib and three of their metabolites in human plasma using LC
Long non
5
Effect of xanthohumol and 8
Edaglitazone 213411
(Rp)
2,2',7,7'
N,N,N',N'
Sirtuin 6 affects glucose reabsorption and gluconeogenesis in type 1 diabetes via FoxO1 PMID 35157928
[Pyr1]
Enhanced apoptosis of squamous cell carcinoma cells by interleukin
Piroctone olamine 68890
Sodium perborate monohydrate (Interox A)
N
NU 1000
Preliminary pharmacokinetics and metabolism of novel non
Sodium 4,4',4'',4'''
1,3,5
4,5
NU
1,4
OAB
1,2
2
The biological evaluation of fusidic acid and its hydrogenation derivative as antimicrobial and anti
Pyridinium, 1,1′
4
Iseganan 257277
E3 ubiquitin ligase that recognizes sugar chains PMID 12140560
Acridone suppresses the proliferation of human breast cancer cells in vitro via ATP
4,4'
Tri(pyridin
4,6
2
MCE
4
Charcot
5
4
1,3,5
Application of student's t
DL
1,3,5
Pharmacology of the anticholinergic bronchospasmolytic agent flutropium bromide PMID 2431695
Isovitexin 2''
3,3'',6,6''
Chk1
1,1'
Norgestimate metabolite Norelgestromin 53016
Synthesis and biological evaluation of 2
4,4'
9,10
Sodium 2
2,7
4,2' 6',4''
1,4
Comparative Analysis of Long Non
Glucose Transporter GLUT4 抗体 (YA753)（Glucose Transporter GLUT4 Antibody (YA753)）
4
FFN511 (Standard)
1,3,6,8
1,3,5
Galacto
Cathepsin B deficiency disrupts cortical development via PEG3, leading to depression
3,3',5,5'
[1,1′ 4′,1′′
D
Current landscape of phosphodiesterase 10A (PDE10A) inhibition PMID 22834877
3
MCE
EBET
2
Overexpression of human DNA polymerase theta is a biomarker of aggressive and DNA repair
Biochemical and pharmacological profile of darexaban, an oral direct factor Xa inhibitor PMID 22040919
Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus PMID 38843792
Droxidopa
Comparison of the Arrhythmogenic Actions of (
Janus Kinase 1 (JAK1)
Development of an enzyme
Columbin inhibits cholesterol uptake in bloodstream forms of Trypanosoma brucei
CBP
Relaxation of vascular smooth muscle by HA
Phleomycin G 11031
l
MAGE 家族成员 A12（MAGEA12）基因
4,4',4''
PROTAC CDK2/4/6 Degrader
High expression of SLC7A1 in high
Allylestrenol 432
An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases PMID 29163222
Rationally Designed Amanitins Achieve Enhanced Cytotoxicity PMID 35696491
3,3′
Changes in Na channel properties of frog and rat skeletal muscles induced by the AaH II toxin from the scorpion Androctonus australis PMID 2560170
Qrich1
Microglia
Urolithin C reveals anti
ENT1 抗体 (YA1251)（ENT1 Antibody (YA1251)）
WYJ
DMN
HDAC
5'
Calcitroic acid
MMP
Chlormadinone 1961
1,3,5
4
MCE
3,5
PCN
Amniotic Fluid Transplantation Alleviates Hematopoietic Deficits in Experimental Rat Aplastic Anemia PMID 33414361
Tris(4
4,4',4'',4'''
5
Homatropine hydrochloride 637
Steroidal alkaloid solanidine impedes hypoxia
1,1'
ITGB6
MCE
Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes PMID 9454781
1,1',1''
Radiolabeled 9
[1,1'
4
CENTA 80072
EDAR 蛋白, Rat (HEK293, Fc)
CLCN5 Human Pre
20
PSI 158442
Maleimide
Basic Green 5 6722
Discovery of new [1,4]dioxino[2,3
Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534
5,10,15,20
Netupitant, a Potent and Highly Selective NK1 Receptor Antagonist, Alleviates Acetic Acid
Copper hexadecafluorophthalocyanine (F16CuPc (purified by sublimation))
CL075 256922
MOF
Di(pyridin
整合素亚基 alpha 4（ITGA4）基因
2,6
BODIPY
4,4',4'',4'''
[1,1′ 4′,1′′ 4′′,1′′′
5,5'
2
Ds
Sodium phosphomolybdate
α
PYCR1 Human Pre
Vicia Villosa Lectin (Fluorescein) (VVL (Fluorescein))
(4
1,1'
1,1'
9,10
Inolitazone hydrochloride hydrate 1048002
4
α
Small
MOF
InhA
2
3
2
rel
Mycoplanecin B 81018
Bis(4
5′
3,6
Comparative in vitro activities of GSK2251052, a novel boron
4'
Dolichos Biflorus Agglutinin (Fluorescein) (DBA (Fluorescein))
(Rac)
2,3
3,5
5,5'
4'
Nuclear SUMOylation and Proteotoxic Stress Responses to Metals with Different Ligand Preferences PMID 40243484
2,5
2,4,6
4,4',4'',4'''
4,4'
2,6
4,3' 5',4''
TSLP signaling network revealed by SILAC
Combined IL6 and CCR2 blockade potentiates antitumor activity of NK cells in HPV
3,4
轧棉厂复杂亚基 3（GINS3）基因
Modipafant 122957
Microwave hyperthermia enhances radiosensitization by decreasing DNA repair efficiency and inducing oxidative stress in PC3 prostatic adenocarcinoma cells PMID 38583875
Tetrahedral
GRGESP 99896
TLR8, but not TLR7, induces the priming of the NADPH oxidase activation in human neutrophils PMID 25877926
A new prenylated flavonol from the roots of Sophora flavescens PMID 9868163
Pharmacological inhibition of SETD7 by PFI
Alkylphosphocholine analogs for broad
(1r,4r)
3
RAS inhibitor Abd
Pravastatin lactone 85956
L
GW 275175X 217950
Thiram
Murrayafoline A attenuates the Wnt/beta
5
(Rac)
Tepotinib hydrochloride 1103508
SphK1
Epstein
Host and viral determinants for efficient SARS
Dried bear bile exerts its antidepressant effect by modulating adrenal FXR to reduce peripheral glucocorticoid levels PMID 39290473
Rhamnose Displays an Anti
LINC01133 promotes the progression of cervical cancer via regulating miR
aTAG 2139
Besigliptin tosylate 1177460
endo
MCE
Oncogenic role of the SOX9
Ramatercept 1169766
Tamra azide 1006592
(S)
Dimethocaine hydrochloride 553
Direct Growth Inhibitory Effect of Platelet Activating Factor C
CXCL12 promotes atherosclerosis by downregulating ABCA1 expression via the CXCR4/GSK3β/β
Mucin corona delays intracellular trafficking and alleviates cytotoxicity of nanoplastic
Effect of Intra
Boc
NFIL3 Facilitates Neutrophil Autophagy, Neutrophil Extracellular Trap Formation and Inflammation During Gout via REDD1
Polydatin alleviates traumatic brain injury Role of inhibiting ferroptosis PMID 33839410
mmu
Punicalagin 65995
Hypersensitivity of myelinated A
Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export PMID 38513023
5,5'
2,2'
2,4
ZIF
Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia PMID 25762638
2,6
HO
Antiviral drugs prolong survival in murine recessive dystrophic epidermolysis bullosa PMID 38462666
Oleandrin induces apoptosis via activating endoplasmic reticulum stress in breast cancer cells PMID 31972357
Prolonged high
2'
Liver
Alkaline Phosphatase (ALP), Porcine Kidney (ALP, Orthophosphoric
((2,5
Naphthoquine phosphate 173531
Methoxytris(perfluorophenyl)silane
PCN 224
4,7
1,1'
1,1'
4,4'
Involvement of galanin and galanin receptor 2 in a mouse model of allergic rhinitis PMID 34412988
Peptide R 1318232
2
25S
[1,1'
Aminoiminomethanesulphinic acid (Thiourea dioxide)
1,3
3’
1,3
Benzenehexathiol
Cardionogen 1 577696
4,4'
1,1
Gli2 Rat Pre
The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells PMID 32634240
2,6
1,1,2,2
Pig TRIM56 mRNA
MOF
Oxcarbazepine
CRBN ligand
Demethyl Benzydamine
Industrial 2,5
5
N1,N5
CRBN ligand
1,2,4,5
4,6
2,2'
4'
5
UTSA
1,3,5
3,3',5,5'
NVC
2,5
Effect of cocoa's theobromine on intestinal microbiota of rats PMID 28605130
5,15
6
4,4',4'',4'''
Pyridine
(R)
4,4',4''
5,5'
MCE
Assessment of corneal nerve regeneration after axotomy in a compartmentalized microfluidic chip model with automated 3D high resolution live
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