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mTOR mutation disrupts larval zebrafish tail fin regeneration via regulating proliferation of blastema cells and mitochondrial functions PMID 38812038
Development of Novel Dihydrofuro[3,4
The Positive and Negative Immunoregulatory Role of B7 Family Promising Novel Targets in Gastric Cancer Treatment PMID 34639059
Mangiferin activates Nrf2 to attenuate cardiac fibrosis via redistributing glutaminolysis
Echinacoside Ameliorates Cyclophosphamide
Investigating theobromine as a potential anti
Flow cytometry of human reticulocytes based on RNA fluorescence PMID 6168453
Mechanisms of resistance to ceftazidime/avibactam in mutants derived in vitro from Klebsiella pneumoniae producing OXA
Discovery of antichagasic inhibitors by high
G
Advantages and Limitations of Bacteriophages for the Treatment of Bacterial Infections PMID 31139086
Lateral to end
Crystalline silica
Bortezomib
Colupulone 21621
Ketohexokinase expression and localization of the principal fructose
High Glucose Activated Cardiac Fibroblasts by a Disruption of Mitochondria
TPBG/5T4 蛋白, Human (HEK293, His)
Nol3 Rat Pre
INHBE
Inotersen sodium 1432726
Megazol
D
Parvalbumin Interneuron
Identification of an autoinhibitory domain in calcineurin PMID 2153670
A small molecule that blocks fat synthesis by inhibiting the activation of SREBP PMID 19716478
GSDMEa
Polyhedral magnetic nanoparticles induce apoptosis in gastric cancer stem cells and suppressing tumor growth through magnetic force generation PMID 39032573
Piceatannol alleviates oxidative stress and ferroptosis in alcohol
miR
Amiquinsin hydrochloride monohydrate 7125
CHRM2 蛋白, Human (His)
Salidroside alleviates atopic dermatitis
CD127/IL
Synthesis and biological evaluation of novel 5(H)
Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage
Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small
ATM inhibitor KU60019 synergistically sensitizes lung cancer cells to topoisomerase II poisons by multiple mechanisms PMID 36650267
Activation of orexin receptor 2 plays anxiolytic effect in male mice PMID 40246189
CA IX
EMA601 and glenzocimab two glycoprotein VI inhibitory Fabs with different potency PMID 40171679
A proof
Runx1 Rat Pre
A clinical experience
Structural and functional characterization of disulfide isoforms of the human IgG2 subclass PMID 18339626
Methylglyoxal
Bile acids in treatment of ocular disease PMID 20046852
RNA
Structure and function of the D
Novel use of FDA
Oncogenic miR
Tobacco
NPHS1 Human Pre
Insulin
A Food Odorant, α
Magnolol effectively ameliorates diabetic peripheral neuropathy in mice PMID 36122436
C
Characterization of VPS34
Protection from lethal apoptosis in lipopolysaccharide
Mitochondrial ROS
Moracenin D from Mori Cortex radicis protects SH
(S,R,R)
Experimental autoimmune thyroiditis
Pre
The utility of N,N
Z
NMDA agonist 1 2576586
Ginsenoside Rb1 induces a pro
Identification and characterization of key kinetic intermediates in amyloid beta
NSUN2/YBX1 promotes the progression of breast cancer by enhancing HGH1 mRNA stability through m5C methylation PMID 38844963
Characteristics of apoptosis induction in human breast cancer cells treated with a ceramidase inhibitor PMID 33270814
Necdin regulates BMAL1 stability and circadian clock through SGT1
Establishment and characterization of an immortalized human giant congenital melanocytic nevi cell line PMID 35218152
MEGF6 Human Pre
Peramivir, an Anti
Structural basis for inhibition of histamine N
Dcc
Alkylaminophenol and GPR17 Agonist for Glioblastoma Therapy A Combinational Approach for Enhanced Cell Death Activity PMID 34440745
Synthesis and biological evaluation of farnesylthiosalicylamides as potential anti
Inhibition of glutaminolysis ameliorates lupus by regulating T and B cell subsets and downregulating the mTOR/P70S6K/4EBP1 and NLRP3/caspase
LOXL2 抗体 (YA1606)(LOXL2 Antibody (YA1606))
Prognostic Value of Urokinase
Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice PMID 21808238
WTAP
Synthesis and evaluation of sulfonamide
Discovery and Structural Optimization of 4
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models PMID 29151587
Fhl2 Rat Pre
ABM
Glucocorticoids enhance chemotherapy
Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design PMID 32534343
TAX1BP1 抗体 (YA2248)(TAX1BP1 Antibody (YA2248))
Polyphyllin I enhances the anti
Dynasore suppresses cell proliferation, migration, and invasion and enhances the antitumor capacity of cisplatin via STAT3 pathway in osteosarcoma PMID 31534119
Microneedle delivery of CAR
STF
Chrysotobibenzyl inhibition of lung cancer cell migration through Caveolin
2
N
Synthesis and biological evaluation of celastrol derivatives as potential anti
Recent Progress on Biological Activity of Amaryllidaceae and Further Isoquinoline Alkaloids in Connection with Alzheimer's Disease PMID 34500673
Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors PMID 20655237
Icariside II inhibits tumorigenesis via inhibiting AKT/Cyclin E/ CDK 2 pathway and activating mitochondria
Colorectal cancer
Brusatol induced ferroptosis in osteosarcoma cells by modulating the Keap1/Nrf2/SLC7A11 signaling pathway PMID 40494017
PIM2
CRISPR
Synthesis and antitubercular activity of new 1,3,4
The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice PMID 38636434
TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR
GIMAP5 Human Pre
An accelerated Parkinson's disease monkey model using AAV
STREPTOMYCIN, SUPPRESSION, AND THE CODE PMID 14173007
MARTRE family proteins negatively regulate CCR4
Novel quinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV PMID 23566517
cBAF complex components and MYC cooperate early in CD8+ T cell fate PMID 35732731
Discovery of a series of novel 5H
MCE
DiD perchlorate (solution)
Frataxin
Discovery of the macrocycle 11
Polarization profiles of human M
Inhibit ALDH3A2 reduce ovarian cancer cells survival via elevating ferroptosis sensitivity PMID 37247796
Ca2+
Honokiol inhibits androgen receptor activity in prostate cancer cells PMID 24338950
The dolichol pathway of N
Blocking c
A behavioural and neurochemical study in rats of the pharmacology of loreclezole, a novel allosteric modulator of the GABAA receptor PMID 9014139
Synthetic biodegradable hydrogel (PleuraSeal) sealant for sealing of lung tissue after thoracoscopic resection PMID 19660330
LasB
Integrated genomics reveals cellular senescence
Targeting N
Resistance to pyridine
Paradoxical effects of PDGF
Pentosidine TFA 225784
Tauroursodeoxycholic acid (TUDCA) disparate pharmacological effects to lung tissue
2,2'
PTER
Iptacopan TFA (LNP023 TFA)
Primisulfuron
E
RM
Identification of a Potent and Selective Focal Adhesion Kinase Proteolysis Targeting Chimera Targeting Noncatalytic Functions of Focal Adhesion Kinase to Facilitate Antitumor Immunity PMID 40742040
AAPDNRETF
PMX
Commiphora mukul extract
Alectinib versus crizotinib in treatment
Triazine Probes Target Ascorbate Peroxidases in Plants PMID 31138623
Neuropeptide Y protects rat cortical neurons against β
Rational design, synthesis and computational studies of multi
RGH
N7
XBP1s acts as a transcription factor of IRE1α and promotes proliferation of colon cancer cells PMID 36828260
Tagatose
Effects of PD
An equilibrium binding study of the interaction of aspartate transcarbamylase with cytidine 5'
INSM1 increases N
Peristromal niches protect lung cancers from targeted therapies through a combined effect of multiple molecular mediators PMID 38712093
Acquired temozolomide resistance in MGMTlow gliomas is associated with regulation of homologous recombination repair by ROCK2 PMID 35145081
Discovery of CDC42 Inhibitors with a Favorable Pharmacokinetic Profile and Anticancer In Vivo Efficacy PMID 38866385
Proteasomal degradation of WT proinsulin in pancreatic beta cells PMID 35988641
The effect of a selective neuronal nitric oxide synthase inhibitor 3
Eprotirome (Standard)
MID1 相互作用蛋白 1(MID1IP1)基因
Antifungal agent 37 2833772
Cdkn2b Mouse Pre
Observation of endoplasmic reticulum tubules via TOF
Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model PMID 19166957
Docking for EP4R antagonists active against inflammatory pain PMID 38057319
Noncanonical UPR factor CREB3L2 drives immune evasion of triple
Structural modification of luteolin from Flos Chrysanthemi leads to increased tumor cell growth inhibitory activity PMID 27353532
Inhibition of ER stress by targeting the IRE1α
Acid
Structure
Immune response associated with Toll
Exploring bat
Linoleoyl Carnitine (N
Design and discovery of 4
Thalidomide decreases high glucose
NNMT/1
Yiqi Wenyang Formula ameliorates diabetic kidney disease via inhibiting inflammation and regulating the gut microbiota
Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP
NAT10 Mediates Cardiac Fibrosis Induced by Myocardial Infarction Through ac4C Modification of TGFBR1 mRNA PMID 40794120
Studying Histone Deacetylase Inhibition and Apoptosis Induction of Psammaplin A Monomers with Modified Thiol Group PMID 33488962
FITC
Breviscapine targets EGFR and SRC to abrogate diabetes
Gnl2
Hirsutine mitigates ferroptosis in podocytes of diabetic kidney disease by downregulating the p53/GPX4 signaling pathway PMID 39864575
GPR56 facilitates hepatocellular carcinoma metastasis by promoting the TGF
Danhong Injection Attenuates High
Xylose
Entrectinib, a Pan
Mechanism of Gastrodin against neurotoxicity based on network pharmacology, molecular docking and experimental verification PMID 39461014
Five undescribed steroids from Talaromyces stipitatus and their cytotoxic activities against hepatoma cell lines PMID 34087503
The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4 PMID 31522764
APAF1
ILK inhibition reduces osteophyte formation through suppression of osteogenesis in BMSCs via Akt/GSK
Cardiac Tissue Factor Regulates Inflammation, Hypertrophy, and Heart Failure in Mouse Model of Type 1 Diabetes PMID 34155039
SVMDLF A novel R
Discovery of 3
Enhancing PDT efficacy in NMIBC Efflux inhibitor mediated improvement of PpIX levels and efficacy of the combination of PpIX
[Pathogenic factors of mycoplasma] PMID 26632216
The pharmacological basis for nonpeptide agonism of the GLP
A novel pan
Role of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice PMID 24552495
Noncanonical farnesoid X receptor signaling inhibits apoptosis and impedes liver fibrosis PMID 30337250
Reductive TCA cycle metabolism fuels glutamine
A compendium of kinetic modulatory profiles identifies ferroptosis regulators PMID 33686292
Effects of diphyllin as a novel V
Network pharmacology, molecular docking, and molecular dynamics simulation analysis reveal the molecular mechanism of halociline against gastric cancer PMID 38504075
Inhibitory effects of a series of 7
Design, synthesis and biological evaluation of exiguamine A analogues as IDO1 inhibitors PMID 34147748
The SNHG10
Pharmacological Evaluation of Cannabinoid Receptor Modulators Using GRABeCB2.0 Sensor PMID 38732230
MCE
Hybrid chemistry. Part 4 Discovery of etravirine
Caspase
Expression and function of Toll‑like receptors in peripheral blood mononuclear cells in patients with ankylosing spondylitis PMID 31485664
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type
PROTAC CDK9 degrader
METTL14 induces ferroptosis to inhibit colorectal cancer progression by inhibiting TRIB3 via an m6A
Prenatal arsenic exposure disrupts placental angiogenesis by altering Pdgfb promoter epigenetic modification PMID 40440895
HOR1
ATS
GX1
Morusalnol A
International Union of Basic and Clinical Pharmacology. XCVII. G Protein
Cbl
MCE
SKF
Identification of a 2
ICOS regulates IL
CX
Synthesis of fluorescent D
In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist PMID 11259574
Inhibition of the angiogenesis and growth of Aloin in human colorectal cancer in vitro and in vivo PMID 23848964
The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells via reducing SP1 and BCL
Differential effects of isomers of clomiphene citrate on reproductive tissues in male mice PMID 26220499
5
A combinatorial strategy for treating KRAS
Nitroxoline mitigates hepatic steatosis by enhancing cholesterol efflux and promoting bile acid synthesis through LRH
PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis PMID 37620972
Targeting interferon signaling and CTLA
氧阿苯达唑
Class II
Genotype and subtype profiling of PSI
t
Gemcabene 183293
IBR1, a novel endogenous IFIH1
The Role of Gut Microbial β
Readily releasable β cells with tight Ca2+
Exploring Trisubstituted adenine derivatives as adenosine A1 receptor ligands with antagonist activity Synthesis, biological evaluation and molecular modelling PMID 40154234
LdCyPA attenuates MAPK pathway to assist Leishmania donovani immune escape in host cells PMID 38190929
A distinct hypothalamus
组蛋白
Plin2
The novel progestin drospirenone and its natural counterpart progesterone biochemical profile and antiandrogenic potential PMID 8922878
2,5
TIE
Novel 2,6
Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with in Vivo Antitumor Activity PMID 31638799
Capmatinib First Approval PMID 32557339
Circular EZH2
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor
Phloretin enhances the efficiency of sheep oocyte IVM and early embryonic development by bolstering antioxidant defenses, inhibiting apoptosis, and promoting development PMID 41240406
Increased mitochondrial fission induces NLRP3/cGAS
胎球蛋白 B(FETUB)基因
Biopolymer
Would carnosine or a carnivorous diet help suppress aging and associated pathologies? PMID 16804013
YAP1, targeted by miR
VER
A Tumor
Dioxoisoindolin
Design of noncompetitive interleukin
IL
MCE
Novel non
The mechanistic study of quercetin in the treatment of alcoholic brain injury via the JNK/P38 MAPK signaling pathway PMID 40457147
SMAC mimetic birinapant inhibits hepatocellular carcinoma growth by activating the cIAP1/TRAF3 signaling pathway PMID 31922244
Synergistic effects of BKM120 and panobinostat on pre
无名指蛋白 8(RNF8)基因
The IKKβ
Isoproterenol inhibits rod outer segment phagocytosis by both cAMP
Grape Seed Extract Attenuates Hepatitis C Virus Replication and Virus
Discovery of Small
Cannabidiol alleviates suture
The HDAC2/SP1/miR
Brain tumoroids treatment prediction and drug development for brain tumors with fast, reproducible and easy
Orexins and appetite regulation PMID 12450737
Combination of a Latency
Synthesis and biological evaluation of quinazoline derivatives
Oxygen
Natural variation in a cortex/epidermis
CRBN ligand
SPHINX 848057
Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome PMID 38522141
Potent non
A novel small
MCE
MCE
Intravenous Multifunctional Nanotherapy for Treating Dry Age
Behavioural study of the D
rno
Saturated fatty acids activate the inflammatory signalling pathway in Schwann cells Implication in sciatic nerve injury PMID 32557749
5
The eIF2 kinase GCN2 directs keratinocyte collective cell migration during wound healing via coordination of reactive oxygen species and amino acids PMID 34597669
Amentoflavone inhibits colorectal tumor growth, stemness, and metastasis, prolonging survival through GLI
Inhibition of calpain reduces oxidative stress and attenuates pyroptosis and ferroptosis in Clostridium perfringens Beta
C3a/C3aR axis is involved in diabetic kidney injury by regulating podocyte mitophagy in diabetic nephropathy PMID 41104892
JH
iPSC Neuronal Assay Identifies Amaryllidaceae Pharmacophore with Multiple Effects against Herpesvirus Infections PMID 26819664
Emerging role of HIC1 in prostate cancer progression and therapeutic response A novel perspective PMID 41050263
Diphyllin, a novel and naturally potent V
HA1/Hemagglutinin 蛋白, H5N1 (AAC32099, HEK293, His)
Zhichuanling oral liquid attenuates airway inflammation in asthma by targeting the STIM1/CHOP/JNK axis PMID 41197928
Consolidation of remote fear memories involves Corticotropin
β
Avoiding Antibiotic Inactivation in Mycobacterium tuberculosis by Rv3406 through Strategic Nucleoside Modification PMID 29663798
The molecular mechanism of berberine affecting psoriasis skin inflammation by regulating keratinocyte pyroptosis via the p38 MAPK/NF
Phenylacetylglutamine produced from injury lung alveolar epithelial cells promotes the function of BMSCs by regulating NONRATT006276.2/Mapt pathway PMID 40413470
Foot
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety PMID 36446933
Dopamine D1 receptor agonist alleviates acute lung injury via modulating inflammatory responses in macrophages and barrier function in airway epithelial cells PMID 36965538
A fragment
Piperine inhibits colorectal cancer migration and invasion by regulating STAT3/Snail
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection PMID 38987588
ZG16B 蛋白, Human (P.pastoris, His)
Recent advances in the discovery and development of glyoxalase I inhibitors PMID 31879183
2',6'
Bag2
NFKB1
CTBP1 links metabolic syndrome to polycystic ovary syndrome through interruption of aromatase and SREBP1 PMID 39294274
1
Design, synthesis, and anticancer properties of isocorydine derivatives PMID 29103873
Tyrosol attenuates pro
LRRC8A is responsible for exosome biogenesis and volume regulation in colon cancer cells PMID 37129855
Sphere
GS
The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor
Bilirubin Oxidase, Myrothecium verrucaria
Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation PMID 38772365
DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition PMID 40295725
RNA m6A
Modification of the natural progression of epileptogenesis by means of biperiden in the pilocarpine model of epilepsy PMID 29096134
Design of G
Noncanonical TCA cycle fosters canonical TCA cycle and mitochondrial integrity in acute myeloid leukemia PMID 39479926
Ac
SDH
OTUD1 promotes isoprenaline
Effects of novel monoamine oxidases and cholinesterases targeting compounds on brain neurotransmitters and behavior in rat model of vascular dementia PMID 23701539
Sodium dithiocarb as adjuvant immunotherapy for high risk breast cancer a randomized study PMID 8389572
Silencing of heat shock protein 27 increases the radiosensitivity of non‑small cell lung carcinoma cells PMID 31115576
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug
MCE
CircCDYL promotes glycolysis to drive the progression of nasopharyngeal carcinoma PMID 41016592
Ercc2
New contrast media in cerebral angiography animal experiments and preliminary clinical studies PMID 6894140
Genomic Engineering of Oral Keratinocytes to Establish In Vitro Oral Potentially Malignant Disease Models as a Platform for Treatment Investigation PMID 38667326
Conjugated Linoleic Acid Ameliorates Hydrogen Peroxide
Macrophage β2
Tobacco
MMPIP hydrochloride (Standard)
Morusalfuran G
Long
Discovery of Novel Selective Inhibitors of SMARCA2 ATPase Domain by Virtual Screening and Biological Evaluation PMID 41089483
Novel antipsychotics activate recombinant human and native rat serotonin 5
Afatinib impurity 33 2475094
Neuropilin
Metabolic changes in glioblastomas in response to choline kinase inhibition In vivo MRS in rodent models PMID 36269130
MCPA sodium 3653
Ibuprofen impurity 1 3585
Adiponectin/Acrp30 蛋白, Cynomolgus (HEK293, His)
Antiviral Agents as Therapeutic Strategies Against Cytomegalovirus Infections PMID 31878068
DL
renin inhibitor
3,5
Antiangiogenic agent 2
CSRP2 promotes the glioblastoma mesenchymal phenotype via p130Cas
SR
Sacubitril/valsartan attenuates myocardial ischemia/reperfusion injury via inhibition of the GSK3β/NF
Treatment of preterm labor with the beta
Aminoadipic acid aggravates atherosclerotic vascular inflammation through ROS/TXNIP/NLRP3 pathway, a harmful microbial metabolite reduced by paeonol PMID 39490917
Iminoboronates a new strategy for reversible protein modification PMID 22642715
信号素 6A(SEMA6A)基因
Difenoconazole
Col6a3
VI 型胶原蛋白 α5 链(COL6A5)基因
NF1 mutation drives neuronal activity
DNA polymerase activity at the single
Inhibitor of glutamine metabolism V9302 promotes ROS
VI 型胶原蛋白 alpha 6 链(COL6A6)基因
Phosphoglucose isomerase, Baker& 039;s Yeast
(2'OMe
Molecular mechanism of action of immune
The influence of aminopterin on limb regeneration in Ambystoma mexicanum PMID 5298244
Novel small molecule glucagon
Preclinical evaluation of [13xLa]La
Design, parallel synthesis and SAR of novel urotensin II receptor agonists PMID 17112638
Maleylsulfathiazole 515
PDK3
Discovery and development of a new oxazolidinone with reduced toxicity for the treatment of tuberculosis PMID 41530381
VI 型胶原蛋白 alpha 3 链(COL6A3)基因
HNRNPC promotes estrogen receptor
1
Halymecin D 167173
HA/Hemagglutinin 蛋白, H1N1 (APT36456, HEK293, His)
STAM2 knockdown inhibits proliferation, migration, and invasion by affecting the JAK2/STAT3 signaling pathway in gastric cancer PMID 33778841
Inhibition of inositol 1,4,5
Mitochondrial dysfunction is involved in aristolochic acid I
Dalazatide 1081110
Docosahexaenoic acid monoglyceride induces apoptosis and autophagy in breast cancer cells via lipid peroxidation
Discovery of 1,1'
Etofenamate 30544
兰屿肉桂提取物 (Cinnamomum kotoense Kaneh. & Sasaki)
HA/Hemagglutinin 蛋白, H1N1 (QEM24690, sf9, His)
Discovery of potent, nonsteroidal, and highly selective glucocorticoid receptor antagonists PMID 12036351
鸟氨酸转氨酶(OAT)基因
Androgen receptor suppresses inflammatory response of airway epithelial cells in allergic asthma through MAPK1 and MAPK14 PMID 35982617
Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity PMID 37873559
Pyrrole and furan oligoglycosides from the starfish Asterina batheri and their inhibitory effect on the production of pro
(E/Z)
The key role of the NUDT3 gene in lung adenocarcinoma progression and its association with the manganese ion metabolism family PMID 39878845
Glucocorticoids exacerbate hypoxia
Hedgehog/GLI
A Multiscale Molecular Dynamic Analysis Reveals the Effect of Sialylation on EGFR Clustering in a CRISPR/Cas9
Genomic and Immune Profiling of Esophageal Squamous Cell Carcinoma Undergoing Neoadjuvant Therapy Versus Upfront Surgery Identifies Novel Immunogenic Cell Death
Acetic acid activates the AMP
UPLC
GlyT1 Inhibitor 1 1820934
Activated DPG Subunit 1044241
MDFI Human Pre
AstC
COX6A1 Human Pre
NCAM2
Silica nanoparticles perturbed mitochondrial dynamics and induced myocardial apoptosis via PKA
K02288 (GMP)
Stigmasta
(
Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability PMID 35177476
FAP targeting peptide for FXX489 3076328
Arg121
Niflumic acid inhibits goblet cell degranulation in a guinea pig asthma model PMID 22377526
Jasmonic acid 6894
SYK Inhibition Potentiates the Effect of Chemotherapeutic Drugs on Neuroblastoma Cells in Vitro PMID 30744170
STING induces HOIP
Synthesis and structure
LAIR
Hexokinase 2 couples glycolysis with the profibrotic actions of TGF
Glimepiride sulfonamide
Methylprednisolone, valacyclovir, or the combination for vestibular neuritis PMID 15269315
Chromatin remodeling controls Kaposi's sarcoma
6
CS
Design, synthesis, and evaluation of quinolin
S1PR1 agonist 1 2700209
Exploration of 3
Pestalotiopisorin B, a new isocoumarin derivative from the mangrove endophytic fungus Pestalotiopsis sp. HHL101 PMID 30623682
RhlR agonist
Design and synthesis of 4'
MRFAP1 Human Pre
Ethyl phenylglyoxylate
Strand break
(1S,2R)
MCE
4
Thalidomide
Microparticles incorporating dual apoptotic factors to inhibit anti
Peroxiredoxin2 (Prdx2) Reduces Oxidative Stress and Apoptosis of Myocardial Cells Induced by Acute Myocardial Infarction by Inhibiting the TLR4/Nuclear Factor kappa B (NF
Synthesis of novel 6
The neuropeptide allatostatin C from clock
Thiazolopyrimidine derivatives as novel class of small molecule tyrosinase inhibitor PMID 37981674
LCN1
CRBN ligand
Fontolizumab, a humanised anti
RNA m6A methylation regulates CDH6 to promote epithelial
Long
Teduglutide
TLR7/8 antagonist 2 2769085
A novel anti
High
Network pharmacology
Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation PMID 35316296
Euparone 53947
Mad1 (6
WRW4 878557
ETI41 2773474
Studying Antifatigue Mechanism of Tyr
MCE
PLLA3000
Activating Mutations in PAK1, Encoding p21
Combination therapy with WEE1 inhibition and trifluridine/tipiracil against esophageal squamous cell carcinoma PMID 37724648
Hippocampal microRNA
10199
RPGRIP1 样(RPGRIP1L)基因
FOSL2 promotes intertumoral infiltration of T cells and increases pathological complete response rates in locally advanced rectal cancer patients PMID 36997107
MAO
MMP
Inhibitory effect of a prostaglandin E receptor subtype EP(1) selective antagonist, ONO
Rupestonic acid 83161
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