最近收录_第824页_生物活性分子
生物活性分子最近更新
Basiliximab a review of its use as induction therapy in renal transplantation PMID 14664658
Plasiaticine B
IL
ATF5 抗体 (YA2184)(PBS only)（ATF5 Antibody (YA2184)(PBS only)）
5
FETUB Human Pre
NSC 727357 910229
ATOX1
DT678
嘌呤能受体 P2 X 3（P2rx3）基因
m
RhoA
ENU
NF
A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis PMID 21211521
beta
NF115
HSPA1A
Rac1
LY86
NF
trans
trans
NCT
DA
Hypoxia
LCN1 Human Pre
The cryo
HSC mobilizer
MZH29 is a novel potent inhibitor that overcomes drug resistance FLT3 mutations in acute myeloid leukemia PMID 27773927
SHP631
Conofurin
13
STIM2 Human Pre
CHNQD
AGT
Pholidotol C 1013909
Ly86 Rat Pre
Gentamicin B
TRTK
MCE
Bay
Br
Neuromedin S(rat) 843782
DYKDDDDK Tag (FLAG) 抗体 (YA780)（DYKDDDDK Tag (FLAG) Antibody (YA780)）
Selective translational control by PABPC1 phase separation regulates blast crisis and therapy resistance in chronic myeloid leukaemia PMID 40102686
Challenges in the Discovery of Indoleamine 2,3
Preclinical and clinical evaluation of recombinant human macrophage colony
Monoclonal antibody
Luteolin combined with low
CK2α
Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence PMID 31706639
Anticancer function of polyinosinic
Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma PMID 19220580
Mifamurtide 83461
Atracurium besylate 64228
Inhibition of plasma kallikrein by a highly specific active site blocking antibody PMID 24970892
Free radical scavenging and antiproliferative properties of Biginelli adducts PMID 22410248
Synergistic interactions between two alpha(2)
DCPIB, an Inhibitor of Volume
The emerging roles of human trace amines and human trace amine
Discovery of tricyclic HIV
The sonic hedgehog pathway suppresses oxidative stress and senescence in nucleus pulposus cells to alleviate intervertebral disc degeneration via GPX4 PMID 37979732
A Pyk2 inhibitor incorporated into a PEGDA
THAP7 Human Pre
Shh
P
Ins(1)P1
Heparin
RB loss determines selective resistance and novel vulnerabilities in ER
Digestion characteristics of quinoa, barley and mungbean proteins and the effects of their simulated gastrointestinal digests on CCK secretion in enteroendocrine STC
Methylbenzethonium chloride 25155
ATAD1 Regulates Neuronal Development and Synapse Formation Through Tuning Mitochondrial Function PMID 39795902
Maz
Octadecanal (Standard) (Stearyl aldehyde (Standard)，十八烷醛 (标准品))
Biotin
Lymphotoxin
Differential Roles of Lipin1 and Lipin2 in the Hepatitis C Virus Replication Cycle PMID 31752156
Alpinetin protects against myocardial ischemia
LY
FGFR
6
MeO
Effect of oleic acid on induction of steatosis and cytotoxicity in BRL 3A cells PMID 31264285
Levamisole Ameliorates Rheumatoid Arthritis by Downregulating the PI3K/Akt Pathway in SD Rats PMID 39598415
2
Halting Multiple Myeloma with MALT1 Inhibition Suppressing BCMA
Palbociclib isethionate 827022
JAS 239
Talmapimod (Standard)
N2
SHP
Discovery of a Potent and Selective FLT3 Inhibitor ( Z)
(±)
Oil Red O (solution)
Tauroursodeoxycholic Acid Inhibits Clostridioides difficile Toxin
BVT
G protein
20
Pachybasin 2549
5
Folipastatin
Nocardicin A 39391
A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice PMID 24169564
Hydroxychloroquine impurity 1 1449223
MCE
Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency PMID 28388409
Endothelial TRPV4
ZY39 2999673
System
Syntheses of new chlorin derivatives containing maleimide functional group and their photodynamic activity evaluation PMID 26306981
ZLN024 hydrochloride 1883548
Pharmacology and toxicology of artelinic acid preclinical investigations on pharmacokinetics, metabolism, protein and red blood cell binding, and acute and anorectic toxicities PMID 9861411
M
Targeting ALK in pediatric RMS does not induce antitumor activity in vivo PMID 29855693
Effects of S‑adenosyl‑L‑methionine on the invasion and migration of head and neck squamous cancer cells and analysis of the underlying mechanisms PMID 32319579
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma PMID 35169126
Ppia Rat Pre
Talmapimod 309913
Anti
Wy
Ligustilide Suppresses Macrophage
Porcine reproductive and respiratory syndrome virus infection activates ADAM17 to induce inflammatory responses PMID 38555788
Theleganbanin C
FATP1
GRI918013 313685
A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC
Kcnn4 Mouse Pre
Acetic acid is an oxidative stressor in gastric cancer cells PMID 30087542
ShSPI Inhibits Thrombosis Formation and Ischemic Stroke In Vivo PMID 39201690
Lys
Innovative selection approach for a new antifungal agent mefentrifluconazole (Revysol®) and the impact upon its toxicity profile PMID 31026541
Loss of p19Arf promotes fibroblast survival during leucine deprivation PMID 34994382
Discovery of a new class of immunosuppressants from Trichothecium roseum co
SIRP alpha V2/CD172a 蛋白, Human (Biotinylated, HEK293, His
Paracrine Ovarian Cancer Cell
Thymidine and 2'
Three chemosensory proteins from the sweet potato weevil, Cylas formicarius, are involved in the perception of host plant volatiles PMID 34037312
Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat PMID 15219839
MCE
A Novel Parkinson's Disease Drug Candidate with Potent Anti
Nemotinic acid 539
Inhibitory effects of Gymnema inodorum (Lour.) Decne leaf extracts and its triterpene saponin on carbohydrate digestion and intestinal glucose absorption PMID 32971162
LPAR1 antagonist 2 1664336
Adipocyte
10(R)
Smad3
Profenofos
N
MCE
The m6A reader IGF2BP3 facilitates myogenesis by activating the CAMK2B
Discovery of Highly Selective and Potent Macrocyclic JAK2 Inhibitors for the Treatment of MPNs PMID 40767151
P
IPrAgCl
CS47 1372792
Intratumoral STING agonist reverses immune evasion in PD
SPPC (1
MCE
Ptges Mouse Pre
Aurintricarboxylic acid, a putative inhibitor of apoptosis, is a potent inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells PMID 7857317
Molecular Determinants of GS
lncRNA MALAT1 potentiates the progression of tongue squamous cell carcinoma through regulating miR
MCE
Chemically defined cytokine
CRM1
Artemisinin exerts a protective effect in the MPTP mouse model of Parkinson's disease by inhibiting microglial activation via the TLR4/Myd88/NF
UiO 66 1072413
NSC 727357
Sodium 5,8
CDK9
遍地金提取物 (Hypericum wightianum Wall. ex Wight & Arn.)
含多个 C2 和跨膜域 1（MCTP1）基因
MK
Exosomal miR
bovine spleen cathepsin D
Effects of Chaga Medicinal Mushroom Inonotus obliquus (Agaricomycetes) Extracts on NOS
RBM8A promotes gastric cancer progression by binding with UPF3B to induce BBC3 mRNA degradation PMID 40613240
Pradefovir 625095
Effect of dexloxiglumide and spiroglumide, two new CCK
Alpha
Antioxidant agent
BFE
Teglicar
MAO A/HSP90
Mavorixafor trihydrochloride 2309699
FATP1
Bromo
Flavopiridol 146426
S 1360 280571
Growth retardation induced in rat fetuses by maternal fasting and massive doses of ergocalciferol PMID 3494110
(BHQ
Apatinib
Synthesis, in vitro evaluation, and in vivo metabolism of fluor/quencher compounds containing IRDye 800CW and Black Hole Quencher
Hydrogen sulfide upregulates renal AQP
The effect of ticlopidine on human endothelial cells in culture PMID 6369618
ERα degrader 14 2991580
BRD9 Degrader
BRL
KDR
NF 115
YKAs
PDE5
1,3
G6PI protein
Fluorescence spectroscopy of Rhodamine 6G concentration and solvent effects PMID 24239710
MCE
Study on Liposomal Encapsulation of New Bodipy Sensitizers for Photodynamic Therapy PMID 29670694
半胱氨酸蛋白酶
PSCA 抗体 (YA5511)（PSCA Antibody (YA5511)）
N
Arachidonic acid
Interaction of OTC drug noscapine and acenocoumarol and phenprocoumon PMID 30809820
Redox
DNA
RS
7,8
Clitocine potentiates TRAIL
Thymoquinone administration ameliorates Alzheimer's disease
The standardized functional observational battery Its intrinsic value remains in the instrument of measure The rat PMID 27534836
Synthesis, biological evaluation, and quantitative structure
α
Novel imino sugar derivatives demonstrate potent antiviral activity against flaviviruses PMID 19223639
AC
m
K145 hydrochloride 1449240
IL
Peptide YY (pig) 81858
Mbip Mouse Pre
Chlorogenic acid attenuates cyclophosphamide
eIF4E S209 phosphorylation licenses myc
Eaf1 Mouse Pre
吞噬和细胞运动 1（ELMO1）基因
CRBN ligand
Irisin suppresses PDGF
FTO
N
Therapeutic targeting of the hepcidin
Metabolomic Analysis of Murine Tissues Infected with Brucella melitensis PMID 39605528
Rrm1 Rat Pre
Synthesis of anilino
Valerylcarnitine
LMCT
Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry PMID 15020595
Beyond Osimertinib The Development of Third
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates PMID 24516150
Deuterium MRI of serine metabolism in mouse models of glioblastoma PMID 38946234
3
Polyhydroxylated azepanes as new motifs for DNA minor groove binding agents PMID 11755363
Identification of 8
Loss of OLFM4 promotes tumor migration through inducing interleukin
Roles of Adam8 in Neuroinflammation in experimental ischemic Stroke Insights from single
Pathologic changes in blood vessels following administration of an inotropic vasodilator (ICI 153,110) to the rat PMID 2361578
Characteristic metabolite profile of 10 colorectal cancer
ABAO
Potent antileukemic activity of the novel cytostatic agent avarone and its analogues in vitro and in vivo PMID 3839712
Peruvoside 1182
The GPR88 Agonist RTI
Discovery of 2
The ER Stress Inducer l
BAG2 Human Pre
Three small molecule pan activator families of Ras
Epigenetic inheritance of a cocaine
Discovering High Potent Hsp90 Inhibitors as Antinasopharyngeal Carcinoma Agents through Fragment Assembling Approach PMID 33543615
Dextran Sulfate Sodium (DSS)
Arginyl
Anticancer properties of the novel nitric oxide
FOXM1
mmu
Enzymatic sulfation of steroids I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations PMID 1278101
SDZ
Isoviolanthin promotes Schwann cells activity in peripheral nerve regeneration via Fhl3
ROC
CPProtectides Rapid uptake of well
Acod1
Pyocyanine
A Novel Small Molecule Which Increases Osteoprotegerin Expression and Protects Against Ovariectomy
Nuclear RNA
Non
GPR65 as a potential novel therapeutic target for the treatment of hepatic fibrosis PMID 38191565
Systematic Structure
Disperse Orange 44 4058
Click. Screen. Degrade. A Miniaturized D2B Workflow for Rapid PROTAC Discovery PMID 41575171
Highly efficient total synthesis of the marine natural products (+)
Lipid
Montanastatin 14410
TLR7/8 agonist 14
HO 221 105128
Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma PMID 28404959
Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands Implications for Intracellular Imaging PMID 26270632
The small molecule NS11021 is a potent and specific activator of Ca2+
ROCK1 drives colorectal cancer liver metastasis via PRKCH
Cloning and characterization of CYP4F21 a prostaglandin E2 20
(
Fmoc
DMU371
Metrnl alleviates lipid accumulation by modulating mitochondrial homeostasis in diabetic nephropathy PMID 36812572
Fexaramate 592524
Two squalene synthase inhibitors, E5700 and ER
ETE
Boromycin 34524
Hydroxychloroquine impurity 3 645406
ST1326
(S)
Hydroxychloroquine impurity 4 69559
Cetraxate raises levels of calcitonin gene
human iNOS
Rational design, synthesis, and biological evaluation of Raloxifene
ATTO 590 biotin 2243123
12
NSC
Bromuconazole exposure induces cardiac dysfunction by upregulating the expression LEF1 PMID 38735319
ST
N
Profound, non
Guaiacylacetone 2503
SEN205A 958712
CAPN15 Human Pre
JAS
Antiparasitic agent
Cytotoxic and antiplasmodial compounds from the roots of Strophioblachia fimbricalyx PMID 19778068
Highly potent and selective histone deacetylase 6 inhibitors designed based on a small
3D structural conformation and functional domains of polysialyltransferase ST8Sia IV required for polysialylation of neural cell adhesion molecules PMID 25329332
The degradation of TGR5 mediated by Smurf1 contributes to diabetic nephropathy PMID 37481723
A quantitative LC
An overview of the biology of a long
X15695 353258
3’
Activating transcription factor 6 protects against endothelial barrier dysfunction PMID 35933031
Airborne fine particulate matter alters the expression of endothelin receptors in rat coronary arteries PMID 27461751
MCE
Mefentrifluconazole 1417782
In vitro activity of new quinoxaline compounds against Campylobacter species and Clostridium difficile PMID 8243041
The flavonoid kurarinone inhibits clinical progression of EAE through inhibiting Th1 and Th17 cell differentiation and proliferation PMID 30031314
N
IL
Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity PMID 40446807
MCE
Paeonolsilate sodium 827610
ALCAM/CD166 蛋白, Rat (HEK293, Fc)
Replacing PEG
Slc1a3
Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non
N
FHL2 Human Pre
Ppia Mouse Pre
Oxychlordane 27304
Palmatine attenuates the doxorubicin
Capsidiol 37208
Ramoplanin 76168
Aggregates of saturated phospholipids at the air
Bis(1H
1,2,3,4,6
Recent Update on the Development of PCSK9 Inhibitors for Hypercholesterolemia Treatment PMID 36446632
Identification of potent human neutralizing antibodies against SARS
Rubicon siRNA
4
ER Stress is Involved in Mast Cells Degranulation via IRE1α/miR
Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway PMID 35224782
FHND5071 2761152
Caspase inhibition and limitation of myocardial infarct size protection against lethal reperfusion injury PMID 10807653
ML
JZP
(S)
BS
Matrine disturbs the eimeria necatrix
Production of anti
Identification of potential molecular targets of luteolin in the treatment of hepatocellular carcinoma based on network pharmacology and transcriptome sequencing technology PMID 40778996
The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils PMID 18930726
GR
Transcription factor Nrf2 binds to circRNAPIBF1 to regulate SOD2 in lung adenocarcinoma progression PMID 36193777
Citrate
D
Kisspeptin
Anticancer agent 110 887349
Oroxylin A suppress LL
BC
The α₁B
16
Discovery of BMS
Regulatory T cells were recruited by CCL3 to promote cryo
Effects of Dimethyl Phthalate (DMP) on Serum Sex Hormone Levels and Apoptosis in C57 Female Mice PMID 31372171
KYNA Ameliorates Hepatic Ischemia
Fluconazole 86386
Synthesis, in vitro antitumor evaluation and DNA
Odiparcil 137215
Antioxidant properties of nitecapone (OR
Bioactive peptides from barley protein hydrolysate stimulate cholecystokinin secretion via calcium
Chromatographic separation and detection methods of Aloe arborescens Miller constituents A systematic review PMID 28535423
Melithiazole C 214420
dipeptidyl peptidase 4 (DPP
DL
First small
Antitumor and antimigration effects of a new Pt compound on neuroblastoma cells PMID 35688179
LAH4
Mucosal unadjuvanted booster vaccines elicit local IgA responses by conversion of pre
Postinfection passive transfer of KD
CRBN ligand
OAT Human Pre
MAdCAM1 蛋白, Human (299a.a, HEK293, His)
Use of phenylboronic acids to investigate boron function in plants. Possible role of boron in transvacuolar cytoplasmic strands and cell
6,7
ALKBH5
CDCA7
MCE
Kaposi sarcoma
A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage PMID 37587444
VHL regulates the sensitivity of clear cell renal cell carcinoma to SIRT4
SIRP alpha V4/CD172a 蛋白, Human (Biotinylated, HEK293, His
Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice PMID 40429989
Nur77 ameliorates age
3'
Patient
2
TH588 hydrochloride 1640282
Inhibition of the ILK
Recent advances in the pharmacological management of constipation predominant irritable bowel syndrome PMID 31724881
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 PMID 35675511
The estrogenicity of methylparaben and ethylparaben at doses close to the acceptable daily intake in immature Sprague
Medical therapy for sudden death PMID 15331289
Regulation of lipoxygenase
Stearic acid
CP
Thrombin receptor 14
FNDC5 attenuates obesity
Accelerated neurite growth from spiral ganglion neurons exposed to the Rho kinase inhibitor H
Improving Payload Capacity and Anti
The first visualization of chemotherapy
PROTAC c
Design, synthesis, molecular docking and 3D
Emodepside 155030
Nkg7
Insulin Exacerbates Inflammation in Fibroblast
5
Prognostic and chemotherapeutic implications of a novel four
ADAMTS12 Human Pre
Determining the chemical profile of Caragana jubata (Pall.) Poir. by UPLC
Meclofenoxate hydrochloride 3685
Quercetin as a Lyn kinase inhibitor inhibits IgE
Blue light pollution induces dry eye by damaging conjunctival stem cells through cAMP
Evaluation of di
CD73 inhibitor AB680 suppresses glioblastoma in mice by inhibiting purine metabolism and promoting P2RY12+ microglia transformation PMID 40500344
6
2',3'
STO
Optimization of a Luteolin
A humanized 4
Vortosiran 3061406
Vancomycin pretreatment attenuates acetaminophen
GSK983 a novel compound with broad
Chemotherapy
Synthesis, anti
Role of Epac1 in mediating anti
Pifithrin
Discovery of the First Efficacious Adenosine 2A Receptor Negative Allosteric Modulators for High Adenosine Cancer Immunotherapies PMID 39855635
SDHI
Discovery of ML323 as a Novel Inhibitor of the USP1/UAF1 Deubiquitinase Complex PMID 25506968
ITX5061 1252679
Ac
Phytic acid suppresses ischemia
MCE
HPLC analysis of saturated or unsaturated oligoguluronates and oligomannuronates. Application to the determination of the action pattern of Haliotis tuberculata alginate lyase PMID 8864226
Isoform
Two Hippo signaling modules orchestrate liver size and tumorigenesis PMID 36919851
IL
MCM proteins are up
EphB2 蛋白, Mouse (HEK293, His)
神经细胞粘附分子 2（NCAM2）基因
Sec18/NSF
Givastomig 2762499
EZH2 Inhibitor Enhances the STING Agonist‒Induced Antitumor Immunity in Melanoma PMID 34571002
Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics PMID 30567881
METTL3 inhibits autoreactive Th17 cell responses in experimental autoimmune uveitis via stabilizing ASH1L mRNA PMID 36753389
Investigation of the anti
CircHelz activates NLRP3 inflammasome to promote myocardial injury by sponging miR
Discovery of N
Mechanistic Insight into Antiretroviral Potency of 2'
Potently inhibiting cancer cell migration with novel 3H
Strategic design to create HER2
Feedback
Mechanism of RNA m6 A methylation modification regulating NLRP3 inflammasome activation for hand, foot, and mouth disease progression PMID 37409616
MCE
Enhancing the Cell Permeability of Stapled Peptides with a Cyclic Cell
A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti
New potent antibacterial oxazolidinone (MRX
Synthesis and identification of 2,4
Discovery and SAR of 5
CRBN ligand
Differential anti
Environmental conditions affecting re
Endothelial
Arginine methylation
PPARγ agonist
The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae PMID 12661761
Chelation therapy in the treatment of cardiovascular diseases PMID 26892121
Design, synthesis and biological evaluation of novel 3,4,5
Dextran Sulfate Sodium Salt
Inhibitory effects of flavonoids on glucose transporter 1 (GLUT1) From library screening to biological evaluation to structure
共956页
首页
上一页
829
828
827
826
825
824
823
822
821
820
819
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新