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An insight into medicinal chemistry of anticancer quinoxalines PMID 30502116
Role of LuxS/AI
N
RNA sequencing
Tuberculosis inhibitor 9
COA7 Human Pre
CU
6
N
NCRW0005
The synthesis and antileukemic activity of 5
MCE
Methyl (tert
Overview of tyrosine hydroxylase in Parkinson's disease PMID 22483316
Synthesis and evaluation of cyclohexane carboxylic acid head group containing isoxazole and thiazole analogs as DGAT1 inhibitors PMID 24735646
trans
7
Versatile synthesis of the signaling peptide glorin PMID 28326133
Migalastat hydrochloride 75172
Ciprofloxacin hydrochloride monohydrate 86393
Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression PMID 26657155
Ppid Mouse Pre
Timosaponin AIII 41059
METTL3 regulates autophagy of hypoxia
Fluconazole
Erythrosine B free acid 15905
CEACAM5 蛋白, Human (Biotinylated, 83a.a, HEK293, His
KITLG
Antiparasitic agent
Human umbilical cord mesenchymal stem cell exosomes promote elastin production and acute skin wound healing via TGFβ1
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO
Tilorone and Cridanimod Protect Mice and Show Antiviral Activity in Rats despite Absence of the Interferon
Momordicine I 91590
PDE4D 蛋白, Human (His)
信号素 3A（SEMA3A）基因
5,6
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy PMID 31618659
Kavain ablates the radio
Possible Reversal of PTSD
In vivo and in vitro effects of azaconazole on renal function in the Fischer 344 rat PMID 3969677
Car8
Extracellular reduction of ubiquinone
GK16S
CCG
SGK1/SGK
Antileukemic activity
Sema3a
Epelmycin C 107807
MD 1
Montmorillonite 1318
Komaroidine
WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells PMID 31752957
Identification of a RIPK2
Butyrolactone I 87414
Gly
Selective blockade of neurotensin
D
激肽释放酶相关肽酶 8（KLK8）基因
P2Y1/P2Y12 antagonist
Inhibition of HDAC6 by tubastatin A disrupts mouse oocyte meiosis via regulating histone modifications and mRNA expression PMID 32017059
Klk8
Synthetic and medicinal perspective of quinolines as antiviral agents PMID 33609889
MCE
SPAI
MCE
Restrictive usage of monoclonal immunoglobulin lambda light chain germline in POEMS syndrome PMID 18497319
Thymol Induces Conidial Apoptosis in Aspergillus flavus via Stimulating K+ Eruption PMID 30044621
Preventive Anti
mmu
Effect of various antiplatelet agents on acute arterial thrombosis in the rat PMID 8128439
Mupirocin Promotes Wound Healing by Stimulating Growth Factor Production and Proliferation of Human Keratinocytes PMID 35479318
BAG 辅伴侣 2（BAG2）基因
HAIL
The roles of osteoprotegerin in cancer, far beyond a bone player PMID 35523775
Oxathiapiprolin (氟噻唑吡乙酮)
Dipotassium phosphite
Fluoxastrobin (氟嘧菌酯)
26548
Expression and functional activity of myosin II in hyperplastic prostates of varying volumes PMID 36935086
2'
Chemical constituents of the Annona glabra fruit and their cytotoxic activity PMID 25856711
SKI
Fmoc
BEX1 Human Pre
角蛋白（HRNR）基因
Senescent retinal pigment epithelial cells promote angiogenesis in choroidal neovascularization via the TAK1/p38 MAPK pathway PMID 39778673
Discovery of a potent and selective small molecule hGPR91 antagonist PMID 21571530
Biotin
Diacylglycerol, 1
Proximity labeling defines the phagosome lumen proteome of murine and primary human macrophages PMID 39282337
Biotin
MCE
Vislarafusp alfa 2850355
Dibenzothiophene
Biotin
Chroman 1 1273579
Effects of delmadinone acetate on pituitary
Quercetin ameliorates renal injury by promoting UCP1
PNA sequence
Drug Screening of Primary Human Endometriotic Cells Based on Micro
In vitro effects of nonsteroidal anti
Crtc1 Mouse Pre
Nap
Synthesis and evaluation of N
Spiperone 749
MRAP 蛋白, Human (HEK293, hFc)
Nampt
Analysis of a BCOR internal tandem duplication in mouse embryonic stem cell to neuronal precursor differentiation PMID 40646718
7554
What formyl peptide receptors, if any, are triggered by compound 43 and lipoxin A4? PMID 21535079
SC
Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2
Ptges3 Rat Pre
TSO
Biotin
A chaperone
Naphthalene (萘)
Fzd10 Mouse Pre
Interaction of angiogenic basic fibroblast growth factor with endothelial cell heparan sulfate proteoglycans. Biological implications in neovascularization PMID 8739851
Distribution of N
Megazol
Biotin
DMU371
MiTF 抗体 (YA6306)（MiTF Antibody (YA6306)）
Deltorphin 2 122752
Cefcapene (头孢卡品酸)
Darolutamide
Transportan 203716
Lectin histochemistry of human skeletal muscle PMID 6166659
Interaction of selected anthocyanins with erythrocytes and liposome membranes PMID 22396139
UK
Unilateral intranigral administration of β
Induction of apoptosis by oridonin in nonfunctioning pituitary adenoma cells PMID 39188035
G protein
Necrotic, rather than apoptotic, cell death caused by cytochrome P450
A
Chlojaponilactone B Attenuates Lipopolysaccharide
Discovery of potent small molecule inhibitors of histone lysine methyltransferase NSDs PMID 38412693
NCK2 抗体 (YA3293)（NCK2 Antibody (YA3293)）
Discovery of ARD
Cyclopamine and jervine induce COX
Aripiprazole in schizophrenia and schizoaffective disorder A review PMID 20152550
15(S)
HIF
D
NONO regulates m5C modification and alternative splicing of PTEN mRNAs to drive gastric cancer progression PMID 40033337
Trigoxyphins A
Zic1 Mouse Pre
Panax notoginseng saponins ameliorate LPS
Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse models PMID 17179482
Pdcd4 modulates markers of macrophage alternative activation and airway remodeling in antigen
In vitro assessment of deferoxamine on mesenchymal stromal cells from tumor and bone marrow PMID 27915123
Oxagrelate 56611
Novel cross
Gamitrinib TPP hexafluorophosphate (Standard)
SBF2 Human Pre
The in vitro effect of new combinations of carbapenem
Enhanced pharmacological activities of AKR1C3
Identification of a novel SIRT7 inhibitor as anticancer drug candidate PMID 30503501
MLL3 Inhibits Apoptosis of Rheumatoid Arthritis Fibroblast
Pituitary adenylate cyclase activating polypeptide enhances glucose
Liquid chromatography/tandem mass spectrometry method for the quantification of deserpidine in human plasma Application to a pharmacokinetic study PMID 19620026
A phase II trial of Afimoxifene (4
MK
Synthesis and in vitro biological evaluation of novel derivatives of Flexicaulin A condensation with amino acid trifluoroacetate PMID 31494472
Tozuleristide
NEU
mmu
TBK1
RO
6
Andrographolide and its derivatives Current achievements and future perspectives PMID 34315039
Scn3b
Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin
Hypoxia induces the production of epithelial
Autophagy is Required for Remodeling in Postnatal Developing Ribbon Synapses of Cochlear Inner Hair Cells PMID 32032574
CXCR3 Protein
Design, synthesis, and biological evaluation of 5
Effects of taurochenodeoxycholic acid on adjuvant arthritis in rats PMID 21983642
Thrombospondin
m
Nonaethylene glycol monomethyl ether 6048
Sophorabioside 2945
RUNX2 Human Pre
Targeted degradation of estrogen receptor β to overcome Osimertinib resistance in non
TNFSF13
Metabolomics and proteomics study reveals the effects of benzo[a]pyrene on the viability and migration of KYSE
The up
NU6300 2070015
NVP
Placental Lactogen/CSH1 蛋白, Human (Biotinylated, HEK293, His)
扣树提取物 (Ilex kaushue S. Y. Hu)
Xenopus orexin A 254757
2
MCE
ALCAM/CD166 蛋白, Human (HEK293, Fc)
Radix Wikstroemiae
Gnl2 Mouse Pre
Profiling of human stratum corneum ceramides by means of normal phase LC/APCI
BMS
4
CRBN ligand
Ciliary neurotrophic factor (CNTF) New facets of an old molecule for treating neurodegenerative and metabolic syndrome pathologies PMID 26187860
核受体亚科 6 组 A 成员 1（NR6A1）基因
Angptl4
Molecular mechanism of secretory protein EFNA1 in HNSCC and its value in early screening PMID 40578286
Derenofylline 251945
L
Valproic acid magnesium 62959
Clstn1
Loss of aryl hydrocarbon receptor reduces pancreatic tumor growth by increasing immune cell infiltration PMID 40090596
ER cell models
PDGFR
Discovery of VU0409551/JNJ
Relative binding orientation
Benzyl p
Design and synthesis of novel deoxybenzoin derivatives as FabH inhibitors and anti
Intravoxel incoherent motion diffusion
Identification of inflammation related lncRNAs and Gm33647 as a potential regulator in septic acute lung injury PMID 34298039
Discovery of Two Structurally Distinct Classes of Inhibitors Targeting the Nuclease MUS81 and Enhancing Efficacy of Chemotherapy in Cancer Cells PMID 41740057
In vitro activities of novel oxapenems, alone and in combination with ceftazidime, against gram
Profile of nicotinic acetylcholine receptor agonists ABT
P
(D
IL3RA
The matching of electrostatic extrema a useful method in drug design? A study of phosphodiesterase III inhibitors PMID 7751868
Quinolone, everninomycin, glycylcycline, carbapenem, lipopeptide and cephem antibacterials in clinical development PMID 11562293
CL
Cefcanel
CL
OCA983
Antistaphylococcal activity of the novel cephalosporin CB
PLGA nanoparticles, 200nm
New Multitarget Inhibitor Potentiates Antimicrobial Activity of Aztreonam against Metallo
Prinoxodan
Cefcanel 41952
10(S)
hsa
Glu63
Ciamexon 75985
ETX1317 2209871
2
ICI 153110 87164
Design, synthesis and antitrypanosomal activity of heteroaryl
Discovery of p300 histone acetyltransferase inhibitors bearing an imidazo[4,5
CL 232468 96555
Biological activity of BO
10
Spirazidine 1158
miR
BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function PMID 26271008
2′′
CL232468
Design, Synthesis, and Evaluation of β‑Lactamase Inhibitors as Potential Therapeutics for Antimicrobial Resistance PMID 41427211
Cyclosporin B 63775
BM
Convergent syntheses of oral THF 1beta
CL 232468
OCA
S100A16
THF carbapenems. Wyeth Ayerst PMID 11892910
Effects of Chemically Modified Messenger RNA on Protein Expression PMID 26906521
MS8511 hydrochloride 3031788
Bromoenol lactone 88070
Mizoribine 5'
Fendleryl B 2098405
Effect of masoprocol on carbohydrate and lipid metabolism in a rat model of Type II diabetes PMID 10027587
Ciamexon
MAO
LYCBX 223914
OXA
Prinoxodan 111786
A novel P2Y(12) adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models PMID 17479197
BM41332
BX 667 937395
BO1236
Dazonone 105622
Anti
Leniquinsin (U
Daidzein improves muscle atrophy caused by lovastatin by regulating the AMPK/FOXO3a axis PMID 39741316
Arg
Epigenetic regulatory functions of DNA modifications 5
1,2
Gymconopin C
The intestinal microbial metabolite nicotinamide n
Antileishmanial agent
Mucosa‑associated lymphoid tissue lymphoma translocation protein 1 inhibitor, MI‑2, attenuates non‑small cell lung cancer cell proliferation, migration and invasion, and promotes apoptosis by suppressing the JNK/c‑JUN pathway PMID 39119234
Excessive free fatty acid sensing in pituitary lactotrophs elicits steatotic liver disease by decreasing prolactin levels PMID 38985678
Actinomycin D induces p53
Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid
GCN2
Fmoc
Antiparasitic agent
Cholyl
Inhibition of kallikrein
4
MK
Plin2 Mouse Pre
HSF1
C5'
Indaziflam (茚嗪氟草胺)
Sunirine
CGP
Metazosulfuron
SPB07393SC
ZY36
Burixafor (TG
HSF1A (Standard)
Stxbp1
SIK2 enhances synthesis of fatty acid and cholesterol in ovarian cancer cells and tumor growth through PI3K/Akt signaling pathway PMID 31932581
Traumatic injury elicits JNK
D
Optineurin regulates motor and learning behaviors by affecting dopaminergic neuron survival in mice PMID 39428042
Forster resonance energy transfer for studying nucleic acids denaturation A chemical and biological sciences laboratory experiment PMID 32268010
CBP
GCO
Formation of Drosophila germ cells requires spatial patterning of phospholipids PMID 40049172
6
1
Investigation of the teratogenic potential of ochratoxin A and B using the FETAX system PMID 16167345
MCE
TWEAK induces angiogenesis and proliferation of endothelial cells PMID 10085077
MCE
PTEN
Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors PMID 16452239
Synthesis and biological properties of new hexapeptide substrates for vitamin K dependent carboxylase. Evidence for X
Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5
MYO3B
Lauryl linolenate 1286724
Oxacillin sodium salt 1173
6β
4
Methane biogenesis during sodium azide
RhoB affects colitis through modulating cell signaling and intestinal microbiome PMID 36114582
Hydroxy
Fmoc
1
Antibody
Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron
2
Perfluoro
redox active
Acetaminosalol 118
6
Withanolide
Panaxatriol 32791
macrophage activation
Novel antibody cocktail targeting Bet v 1 rapidly and sustainably treats birch allergy symptoms in a phase 1 study PMID 34126156
MI
UBE2H Human Pre
Pseudo
relative stereochemistry
Phenolic constituents with neuroprotective activities from Hypericum wightianum PMID 31229788
Modulation of endothelial cell proliferation by retinoid x receptor agonists PMID 10607884
SCPEP1
Donepezil
N
SARM1
RESA peptide 133699
GLP
Bremzalerbart
EMC
Gut
HepG2 cells
CN
rel
DBCO
Hyperwightin C 2374723
12
Cholyl
liquid
passive anaphylaxis
wild
Anti
NZ28
AL 001
Aristoforin 849215
Enzyme
(S)
Delpacibart zotadirsen 2929240
O
Determination of Penicillium griseofulvum
Multiple Mutations in Mycobacterium tuberculosis MmpL3 Increase Resistance to MmpL3 Inhibitors PMID 33055263
Study on the biosynthesis of the notoamides Pinacol
1
Periodontal ligament stem cells promote polarization of M2 macrophages PMID 34982483
2
Characterization of in vitro generated metabolites of the selective androgen receptor modulators S
Etazolate, a phosphodiesterase 4 inhibitor reverses chronic unpredictable mild stress
头孢托罗
KOdiA
Avarone
8
Correlation between KAT6A and PD
R18 211364
Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L
β
SIRT6
Brilliant sulfaflavine 2391
MCE
1
Effects of inhibitors of carbohydrate absorption or lipid metabolism on meal patterns of Zucker rats PMID 3841213
Symbiobacterium
grain protein
JP
Hepsulfam
MD
KLK8
BVT
TACC3 inhibitor 2
HPSE1
Dynamic changes of inducible nitric oxide synthase expression in rat's retina and its role on blood
Fenofibrate promotes erucic acid metabolism by peroxisome enzyme EHHADH activation alleviating high
Baricitinib
D
ID09, A Newly
ATTO 590 biotin
Cyclohexane triones, novel membrane
Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation PMID 35318857
A stem cell
Synthesis, biological evaluation, molecular docking, and MD simulation of novel 2,4
Differentiation of early mouse embryonic and teratocarcinoma cells in vitro plasminogen activator production PMID 975058
Discovery of Salidroside
2
Antiproliferative agent
A Gram
A g
Sema3a
Oxathiapiprolin
Malotilate reduces collagen synthesis and cell migration activity of fibroblasts in vitro PMID 3318840
Sema3a
GW796406
Epelmycin A 107807
USF2 Human Pre
BPK
BPK
YLT192
Anti
Fmoc
alkanethiol
Lysophosphatidylcholine induces apoptosis in human endothelial cells through a p38
Sutantatug
12β
Mechanism of Ca2+ in regulating pupation defects of Bombyx mori after exposure to chlorantraniliprole PMID 40418763
Opemalirsen
ICI63197
Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types PMID 20150762
Menin
Antitumor agent
p70S6 kinase is a target of the novel proteasome inhibitor 3,3'
19
Leukemia cells demonstrate a different metabolic perturbation provoked by 2
ML264, A Novel Small
Presence, formation and putative biological activities of N
Evidence that 3
MCE
mmu
Pachymic acid (PA) inhibits ferroptosis of cardiomyocytes via activation of the AMPK in mice with ischemia/reperfusion
CD36
W
Aleuria Aurantia Lectin (AAL)
T.cruzi
α
Plant sex pheromones PMID 16492479
2
L002 321695
Intrinsic electrical activity drives small
N
Naringenin
Inhibition of 4EBP phosphorylation mediates the cytotoxic effect of mechanistic target of rapamycin kinase inhibitors in aggressive B
Shepherdin (79
Albendazole sulfoxide
Naphthalene, a versatile platform in medicinal chemistry Sky
ATTO 514 biotin
18 1 PE
PKUMDL
tea leaf spot
Biotin
Interleukin
DMU 371
DMU371 3052352
TSO
HAIL
Salidroside exerts anti
BM 41332
Biotin
Psca
Interaction of protamine sulfate with thrombin PMID 6846326
NITD
THESCs cells
Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti
NaCl
Spirazidine
Prediction and validation based on scRNA
Stress Relaxation
Effector CD4 T
Synthesis and biological activity of amino acid derivatives of avarone and its model compound PMID 26476666
12(S)
High
Mal
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