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D
A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK PMID 30773340
AMOZ 43056
Pyrrolidin
Cyclophosphamide and cancer golden anniversary PMID 19786984
Hesperidin enhanced anti
PGC1α
In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor PMID 23132334
Ac
Zederone 7727
Development and validation of a liquid chromatography
LncRNA TUG1 Repressed Angiogenesis by Promoting the Ubiquitination of HuR and Inhibiting Its Nuclear Translocation in Cerebral Ischemic Reperfusion Injury PMID 39887590
ChEs/MAOs
ZC9 2757513
鞭毛内运输 43(IFT43)基因
Anti
Cytotoxic sesquiterpenes from Aplysia dactylomela PMID 16309323
CKK
Discovery of conformationally rigid 3
LRRK2 and RAB8A regulate cell death after lysosomal damage in macrophages through cholesterol
Nitrative Stress
Dexmedetomidine Protects the Brain Exploring the α2AR/FAK Pathway in Post
Enantiomeric Agonists of the Type 2 Cannabinoid Receptor Reduce Retinal Damage during Proliferative Vitreoretinopathy and Inhibit Hyperactive Microglia In Vitro PMID 38751621
ZIKV
LY2812223
MCE
Effects of sulfathiazole, oxytetracycline and chlortetracycline on steroidogenesis in the human adrenocarcinoma (H295R) cell line and freshwater fish Oryzias latipes PMID 20630653
Tyrphostin A51 126433
CCKBR agonist
DPPG
Long noncoding RNA MIAT regulates TP53 ubiquitination and expedites prostate adenocarcinoma progression by recruiting TBL1X PMID 37356458
Intraperitoneal injection of synthetic bacterial lipopeptides does not cause a rise in circulating inflammatory cytokines PMID 8156054
Identification of Trovafloxacin, Ozanimod, and Ozenoxacin as Potent c
Elucidation of Acquired Resistance to Bcl
Kinase Atlas Druggability Analysis of Potential Allosteric Sites in Kinases PMID 31274316
MCE
AHR
Release of immunomodulatory peptides at bacterial membrane interfaces as a novel strategy to fight microorganisms PMID 36822328
Serine Glycine Restriction Aggravates Hepatic Ischemia
Sparteine 24915
Guavinoside B 372955
Sp
Biologically active prenylated flavonoids from the genus Sophora and their structure
BET
Senktide 106128
Inhibitory effects of limonin on six human cytochrome P450 enzymes and P
Vitamin D3 analogues that contain modified A
Discovery of N
Lipid
Naphthol yellow S, 98% 846
Berberine@AgNPs@Carboxylated chitosan hydrogel dressing with immunomodulatory and anti
Effects of Dendritic Cell Subset Manipulation on Airway Allergy in a Mouse Model PMID 26855055
Thiram
The DNA damage response making it safe to play with knives PMID 20965415
OECs Prevented Neuronal Cells from Apoptosis Partially Through Exosome
Nucleotide
Blockade of HERG channels by the class III antiarrhythmic azimilide mode of action PMID 9484850
Comparison of the cardiac effects of beta
BGB
Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge PMID 10072688
Flipper
On the mode of action of emodepside slow effects on membrane potential and voltage
Phenibut (beta
(Rac)
Polyfunctional T follicular helper cells drive checkpoint
Icterogenin
Mal
Famciclovir in chronic hepatitis B results of a dose
Liposomal Curcumin is Better than Curcumin to Alleviate Complications in Experimental Diabetic Mellitus PMID 30818888
ILC2 regulates hyperoxia
JNJ
Effects of Bay o 2752, a hypocholesterolemic agent, on intestinal taurocholate absorption and cholesterol esterification PMID 2810110
The discovery of potent, orally bioavailable pyrimidine
OMA
1,2
Deoxyharringtonine 36804
Glycine sodium salt hydrate 207300
N
Protease Activated Receptor (PAR)
Activation of G protein
Nitric oxide generated from isoniazid activation by KatG source of nitric oxide and activity against Mycobacterium tuberculosis PMID 15273113
Identification of Compound 15 (MMV1581361) as a Pf ATP4 Inhibitor with Transmission
SIRT1 inhibits apoptosis in in vivo and in vitro models of spinal cord injury via microRNA
Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe PMID 21859926
MCE
Cancer
Sutidiazine 1821293
Downregulated NT
Salidroside attenuates lipopolysaccharide
DBCO
Langerhans cell histiocytosis in children History, classification, pathobiology, clinical manifestations, and prognosis PMID 29754885
Early methionine availability attenuates T cell exhaustion PMID 40702340
2
Analysis of potential targets of 20S
(+)
STAT3
Induction of Chemokines by Hepatitis C Virus Proteins Synergy of the Core Protein with Interleukin
αGlcCer (C24 1 α
Effect of salicylamide on the placental transfer and fetal tissue distribution of sodium
parallel G
Studies on the metabolism of arylacetic acids. 5. The metabolic fate of 2
AMPK Activation Regulates LTBP4
Discovery of small
Rosuvastatin lactone
Teglicar chloride (ST1326 chloride)
Tuberculosis inhibitor 3 2219325
Erythronic acid 13752
Small Trafficking Inhibitor Retro
β
肌球蛋白轻链 11(MYL11)基因
Polyprenol (13~21) 308068
Turmeronol A 131651
An alternative model for type I interferon induction downstream of human TLR2 PMID 32796029
Bacopaside I 382148
Bromoenol lactone, an inhibitor of Group V1A calcium
Spsb3 Mouse Pre
Azido
SLIGRL
Pediocin PA
TEX9 Human Pre
L
MAdCAM1 蛋白, Human (HEK293, Fc)
Dibenzo[a,h]acridine
Granulocyte colony
Dner Rat Pre
Pyrtriazoles, a Novel Class of Store
Synthesis, biological evaluation and mechanism study of a novel indole
Wogonin Alleviates Kidney Tubular Epithelial Injury in Diabetic Nephropathy by Inhibiting PI3K/Akt/NF
Z
KD025 Shifts Pulmonary Endothelial Cell Bioenergetics and Decreases Baseline Lung Permeability PMID 32628869
Ly86
Becondogrel 1416696
Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells PMID 36427655
Morpholino U subunit 2388517
eIF4A3
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient
Roquefortine C 58735
Effects of iloperidone on hERG 1A/3.1 heterotetrameric channels PMID 34605450
Use of cefovecin in dogs and cats attending first
Tobramycin in ophthalmology PMID 3317953
Ferroptosis inducer
Extracellular vesicles of ADSCs inhibit ischemic stroke
m
Folipastatin
Kasugamycin hydrochloride hydrate (Ksg hydrochloride hydrate,春雷霉素盐酸盐水合物)
Removal of partial agonism from parathyroid hormone (PTH)
Synthesis and biological activity of retinoic acid receptor
DCB (Standard)
solid
Talmapimod (Standard) (他匹莫德 (标准品))
E09241
MCE
Electroacupuncture ameliorates cardiopulmonary bypass induced apoptosis in lung via ROS/Nrf2/NLRP3 inflammasome pathway PMID 31628913
Gradient
Unveiling the roles of HIPK2 in atherosclerosis Insights into the β
ETE
7
Cy
cFMS Receptor Inhibitor IV
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis PMID 30158707
MCE
Type A Allatostatin I 123209
Naxe
Efficient One
抑制素亚基β E(INHBE)基因
(24S)
MAT2A
Reduction of myeloid
Dabigatran impurity 1 2417628
Propynyl
Ucf
HRP
SAHM1 2050906
GT
Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization PMID 8505317
USP8 promotes the tumorigenesis of intrahepatic cholangiocarcinoma via stabilizing OGT PMID 38973004
Ac
PLA2G2D 蛋白, Human (His
EPZ011989 1598383
Amocarzine 36590
Puerarin Decreases the Expression of FUS
四氢羟基皮质酮
Fluorobenzene
DL
CRBN ligand
Prolonged Retention of Albumin Nanoparticles Alleviates Renal Ischemia
热休克蛋白家族 A (Hsp70) 成员 1A(HSPA1A)基因
1
Rizatriptan 144034
N
IKKβ
NF
hsa
Inhibition of catechol
Ricolinostat enhances adavosertib‑induced mitotic catastrophe in TP53‑mutated head and neck squamous cell carcinoma cells PMID 35348191
Iguratimod (T
Anti
Ro 04
Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species
Functional Role of Basolateral ClC
BRD4 Inhibitor
beta
Dcc
Mal
Eotaxin/CCL11 is a negative regulator of neutrophil recruitment in a murine model of endotoxemia PMID 12127048
Hydroquinidine 1435
PAB
Bisphenol F promotes the secretion of pro
Centrally administered neuropeptide W
3β
Time
MAP3K12/DLK/Pref
BVFP 357158
PROTAC IRAK4 ligand
Zic1
17
Fmoc
2
Maleic hydrazide
In vitro activities of a novel cephalosporin, CB
Ugdh
AAA
Garbanzol 1226
Fluacrypyrim 229977
PLP (139
Inhibition of hepatitis B virus gene expression and replication by helioxanthin and its derivative PMID 16004082
APG
Double Blockade of Glioma Cell Proliferation and Migration by Temozolomide Conjugated with NPPB, a Chloride Channel Blocker PMID 26711895
trans
DL
Psca
淋巴细胞抗原 86(LY86)基因
Anti
ANXA1 improves mitochondrial homeostasis through uncoupling protein 1 in diabetic nephropathy PMID 41275961
Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway PMID 22687748
Silylanization hyaluronate ester 135507
Cergutuzumab 1622305
PKM2 activator 2 1186660
Monochlorobimane 76421
Effects of suppressing Smads expression on wound healing in Hyriopsis cumingii PMID 31870970
TMB
Preparation, characterization, and bioactivity evaluation of oligosaccharides from Atractylodes lancea (Thunb.) DC PMID 34893263
Establishment of a novel myocarditis mouse model based on cyclosporine A PMID 35666459
CHL1 蛋白, Human (HEK293, His)
Mefatinib 1989592
The role of lncRNA NEAT1 in acute graft
Dihydrofuran
Edaravone sulfate
CRBN ligand
Masoprocol (nordihydroguaiaretic acid) a new antihyperglycemic agent isolated from the creosote bush (Larrea tridentata) PMID 9617755
Effect of an aldose reductase inhibitor, CT
LY
CCI
2,4′
Biotin sulfone (生物素砜)
Chromozym t
UiO 66
EIDD
Phaclofen 114012
Influenza virus
MeO
EphB1
IDO1
2
ATTO 565 biotin
Mu opioid receptor antagonist 1
Doxycycline
Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis PMID 16879647
VUF5834 860002
KDM5A suppresses PML
New Rimocidin/CE
头孢吡普
Targeting ubiquitin
DSP
Lactobacillus maintains healthy gut mucosa by producing L
VEGFR
Trk Receptor
Sinomenine induces apoptosis in RAW 264.7 cell
SFTPC 蛋白, Human (P.pastoris, His)
BFE
Hemiasterlin 157207
Ppid
Hericenone E (猴头菌酮E)
Targeting PEA3 transcription factors to mitigate small cell lung cancer progression PMID 36509998
New estrogenic compounds isolated from Broussonetia kazinoki PMID 20493686
PAN
Oleoyl
Targeting UAF1 Alleviate Neurotoxicity by Inhibiting APP/NLRP3 Axis
Sequence variations of Epstein
A924 65132
DNA
Dysfunction of astrocytic connexins 30 and 43 in the medial prefrontal cortex and hippocampus mediates depressive
Characterization of a novel, water
CRBN ligand
U 92032 142223
Ginsenoside V 1395101
APEG1 蛋白, Human (His)
Aflatoxin B1 and aflatoxin M1 induced cytotoxicity and DNA damage in differentiated and undifferentiated Caco
KARI 201 hydrochloride 2376132
Izorlisib 1007207
GGsTop, a novel and specific γ
TC AC 28 1809296
Orally effective CVS
Oxidative Stress Mediated by N6
Pharmacokinetics of mequindox and its metabolites in rats after intravenous and oral administration PMID 22459092
active
Discovery of a potent β
LpxH
2’
Dcc Rat Pre
BMT
Agt
Stim2
MCE
Zaldaride 109826
MCE
human eNOS
Transcription factor EB (TFEB) promotes autophagy in early brain injury after subarachnoid hemorrhage in rats PMID 37400013
Zotiraciclib hydrochloride 1354567
DNER
Efficacy of a single dose of milbemycin oxime/praziquantel combination tablets, Milpro(®), against adult Echinococcus multilocularis in dogs and both adult and immature E. multilocularis in young cats PMID 26660919
The potential therapeutic effects of hydroxypropyl cellulose on acute murine colitis induced by DSS PMID 35483843
Dlx2 Mouse Pre
Plant
BRD
Tiagabine suppresses pentylenetetrazole
Studies on the possible mutagenic action of metronidazole PMID 3308693
eIF4A3
Tunable triazole
Biological activity of Sch 14342, an aminoglycoside antibiotic coproduced in the gentamicin fermentation PMID 4670439
Synthesis, Anticonvulsant, Antinociceptive Activity and Preliminary Safety Evaluations of Novel Hybrid Imidazolidine
Induction of alloreactive immunosuppression by 1,4
Resveratrol induces apoptosis and inhibits adipogenesis by stimulating the SIRT1
ND1
DPP
miR
Isoamylase 9067
5'
306
CDKL3 is a targetable regulator of cell cycle progression in cancers PMID 38963708
Yuehgesin C
6'
Oat Mouse Pre
Chicken cathelicidin
PhIP 105650
Inhibition of succinyl CoA synthetase histidine
Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis PMID 1943494
sodium succinate buffer
Antineoplastic agents. Part 409 Isolation and structure of montanastatin from a terrestrial actinomycete PMID 10400343
m6A methylation
1,10
The defensive effect of phellodendrine against AAPH
MCE
Novel E. coli beta
Two new triterpenoids from the leaves and stems of Lantana camara PMID 32141312
Mechanism of vasopeptidase inhibitor
Development of an N
Polyhedral alkanes as hydrophobic tags for dual
TLR4 pathway
Gpr141 Mouse Pre
N
Gymconopin C 844493
High
Orally active, species
n
3
Dual
Gentamicin B 36889
Relacorilant
Potential antidepressant activity of rolipram and other selective cyclic adenosine 3',5'
Design, synthesis and immunological evaluation of novel monosaccharide TLR4 agonists PMID 41795437
Overexpression of PON1 reduces high glucose induced renal tubular epithelial cell injury by activating PPARγ signaling pathway to alleviate diabetes nephropathy PMID 40834279
The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heart PMID 20353807
E5700 332132
(E/Z)
A new neuroprotective compound of Ligustrum japonicum leaves PMID 16450298
Nutlin
hCAIX/XII
Synthesis and biological activity of derivatives of the marine quinone avarone PMID 19995673
Ivachtin 745046
VBP1 Human Pre
The phytochemical lindleyin, isolated from Rhei rhizoma, mediates hormonal effects through estrogen receptors PMID 12429027
Dna2 Mouse Pre
Hyperglycemia
BP Fluor 594 NHS ester 1638544
9
Adrenergic agonist induces rhythmic firing in quiescent cardiac preganglionic neurons in nucleus ambiguous via activation of intrinsic membrane excitability PMID 30699052
S 25585
Molecular pathways and related target therapies in liver carcinoma PMID 18045179
Functional characteristic analysis of three odorant
[Glu1]
FK352
Synthesis, molecular modeling, biological and pharmacokinetic evaluation of hydroxy pyrimidinones and pyrimidinediones as novel LDHA inhibitors PMID 40967070
BO
APRIL and TALL
Nor
pseudo
Ongoing and future directions in the management of metastatic colorectal cancer Update on clinical trials PMID 30852840
ANGPTL4
Bromuconazole fungicide induces cell cycle arrest and apoptotic cell death in cultured human colon carcinoma cells (HCT116) via oxidative stress process PMID 35968645
Cefcapene
substrate analog transition state mimic
Lactobacillus paracasei Activates the KDM3A/VAMP1 Axis to Induce Autophagy in Renal Tubular Epithelial Cells in Chronic Kidney Disease PMID 40111701
The interaction between ASF1B and TLK1 promotes the malignant progression of low
Rapid, hydrolytically stable modification of aldehyde
TNIK 蛋白, Human (sf9, His)
Decussatin 20882
PDE5
Apba2 Mouse Pre
Etoxazole 153233
Identification and pharmacological characterization of [125I]L
Spinal segment
PtpB
Dowicil 200 51229
4'
Fragmenting the S100B
Convenient and scalable synthesis of fmoc
Assembly of a novel biosynthetic pathway for gentamicin B production in Micromonospora echinospora PMID 26729212
HIV
Hypoxia Dependent Inhibition of Glioblastoma Cell Proliferation, Invasion, and Metabolism by the Choline
BW
N4
DT
nNOS
Polymyxin Acylase, Pseudomonas sp.
Anti
Rational design
BRL
NACAD Human Pre
Pain is a salient stressor that is mediated by corticotropin
HSC mobilizer1
L
Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3 PMID 22926646
SCH14342
Isobutylparaben
Esculentoside S 156031
Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double
A novel Quinazoline derivative exerts anti
GABAA receptor
SFRP4 contributes to insulin resistance
Lignans from the stems of Clematis armandii ( Chuan
Paeonolsilate sodium
TRK
The Calmodulin
Inhibition of Wnt/β
Carbazochrome sodium sulfonate 51460
The protective effect of HOXA5 on carotid atherosclerosis occurs by modulating the vascular smooth muscle cell phenotype PMID 34126188
TP
MC
SGI
Discovery of ATP competitive PDHK1/2 dual inhibitors PMID 40107630
Ce6
CD226 implicated in Akt
Sec
Modified C
Pyranochromones with Anti
2,2',4,4'
Synthesis and anti
Cystemustine induces redifferentiation of primary tumors and confers protection against secondary tumor growth in a melanoma murine model PMID 11280801
A comparison of the pharmacological profiles of prasugrel and ticagrelor assessed by platelet aggregation, thrombus formation and haemostasis in rats PMID 23347039
Dihydrocapsaicin (DHC) enhances the hypothermia
MCE
Erbin protects against sepsis
OPC
N7,N7
R78206 124436
Effects of inhibition of hepatic sulfotransferase activity on renal genotoxicity induced by lucidin
Emergence of hepatitis C virus NS5A L31V plus Y93H variant upon treatment failure of daclatasvir and asunaprevir is relatively resistant to ledipasvir and NS5B polymerase nucleotide inhibitor GS
Antiosteoporotic activity of anthraquinones from Morinda officinalis on osteoblasts and osteoclasts PMID 19169204
(S)
BMECs Ameliorate High Glucose
Cytokeratin 13 抗体 (YA2695)(Cytokeratin 13 Antibody (YA2695))
Multimechanistic Conjugates Based on Melampomagnolide B and 10
GRP (porcine) 74815
Zidovudine 30516
Natural, synthetic and semisynthetic glycolipid inhibitors of glioma growth PMID 21793650
12
MCE
Carbohydrate microarrays by microcontact click chemistry PMID 18837529
MCE
Rehmannioside A 81720
Rendomab B4 (Rendomab
Carnosol, a diterpene present in rosemary, increases ELP1 levels in familial Dysautonomia (FD) patient
Kresoxim
Natural product derivative Gossypolone inhibits Musashi family of RNA
Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma PMID 39133652
Serpinc1
Selective nucleoside triphosphate diphosphohydrolase
Evaluation of Resmethrin Toxicity to Neonatal Testes in Organ Culture PMID 31593228
AF405
neure
Paracrine secretion of IL8 by breast cancer stem cells promotes therapeutic resistance and metastasis of the bulk tumor cells PMID 36915147
Pharmacological evaluation of analgesic effects of the cholecystokinin2 receptor antagonist Z
Inhibition of the E3 ligase UBR5 stabilizes TERT and protects vascular organoids from oxidative stress PMID 39609696
Impacts of TP53TG1 in cancer
Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin PMID 11062694
MCE
DNA Methylation
Globular adiponectin protects rat hepatocytes against acetaminophen
phosphorite monomer
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