最近收录_第822页_生物活性分子
生物活性分子最近更新
4,4'
1
Icterogenin
AKT
mmu
Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury PMID 32621799
Galectin
ZLN005 protects against ischemia
β4
Netupitant Inhibits the Proliferation of Breast Cancer Cells by Targeting AGK PMID 39594764
Enhancement of l
IER3 Facilitates Tumor Progression and Aberrant Glycolysis via Activating wnt/β
GAP214
Characterization and humanization of VNARs targeting human serum albumin from the whitespotted bamboo shark (Chiloscyllium plagiosum) PMID 38878923
Lucifer Yellow
Salicyl alcohol (Standard) (2
ATF1 抗体 (YA3136)(PBS only)（ATF1 Antibody (YA3136)(PBS only)）
2
Ro 20
MCE
Cbz
Characterization of the novel Trypanosoma brucei inosine 5'
Rat hemopexin. Molecular cloning, primary structural characterization, and analysis of gene expression PMID 1988069
Myristoleyl methane sulfonate 77133
E7050 a dual c
Structure
CPT I
Azaconazole 60207
PPIA
SLC16A3/MCT 4 抗体 (YA6766)（SLC16A3/MCT 4 Antibody (YA6766)）
Expression and antimicrobial function of beta
Unexpected Binding of Tozuleristide Tumor Paint to Cerebral Vascular Malformations A Potentially Novel Application of Fluorescence
Genotoxic damage and apoptosis in rat glioma (F98) cell line following exposure to bromuconazole PMID 36370923
Design, Synthesis, and Structure
Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation PMID 20188172
The neonatal Fc receptor and DPP4 are human astrovirus receptors PMID 39026791
Myosin
Bis
Tropolone Ring Construction in the Biosynthesis of Rubrolone B, a Cationic Tropolone Alkaloid from Endophytic Streptomyces PMID 26926531
IO 21
Indaziflam 950782
2
29β
Hormone
Rosa canina extract 84696
Lauryl laurate 13945
L
Ashimycins A and B, new streptomycin analogues PMID 2503480
E5700
Psca Mouse Pre
Distributed multipoles
Tetrabenazine Racemate 718635
hnRNP U 抗体 (YA5235)（hnRNP U Antibody (YA5235)）
前列腺干细胞抗原（PSCA）基因
PDE5
Diacylglycerol Kinases (DGKs) Novel Targets for Improving T Cell Activity in Cancer PMID 27800476
GLK7
(+)
Oridonin Attenuates Thioacetamide
N
Antitrypanosomal agent 30
KL
Ceftazidime
Nemvaleukin alfa, a novel engineered IL
Genetic and pharmacological inhibition of Kir1 impacts mating behavior of the diamondback moth (Plutella xylostella) PMID 40847487
SIRT3
Expression pattern and clinical significance of MerTK on circulating NK cells in systemic lupus erythematosus PMID 40541265
Study on the Anti
LY
Targeting Anti
Low Wall Shear Stress Promotes Atheroma via Arterial Iron Accumulation PMID 41036559
Termitomycamide E
YKAs3003
Simvastatin hydroxy acid sodium 101314
Recombinant fibroblast growth factor 4 ameliorates axonal regeneration and functional recovery in acute spinal cord injury through altering microglia/macrophage phenotype PMID 38728880
4'
Opposing T cell responses in experimental autoimmune encephalomyelitis PMID 31391585
Constituents from Dolichos lablab L. Flowers and Their Anti
Methyl 2
Establishment and characterization of a novel immortalized human aortic valve interstitial cell line PMID 40157927
TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling PMID 37525222
Design, synthesis, and docking studies of afatinib analogs bearing cinnamamide moiety as potent EGFR inhibitors PMID 26906472
Abnormal cytoskeletal remodeling but normal neuronal excitability in a mouse model of the recurrent developmental and epileptic encephalopathy
IκBα deficiency imposes a fetal phenotype to intestinal stem cells PMID 32270911
Biomimetic targeted self
SphK1 inhibitor SKI II inhibits the proliferation of human hepatoma HepG2 cells via the Wnt5A/β
The coccidian parasites Toxoplasma and Neospora dysregulate mammalian lipid droplet biogenesis PMID 28487365
Schistosoma japonicum leishmanolysin SjLLPi1 facilitates the invasion of cercariae into the host skin PMID 40857348
Rational design of 2
Ethanolamine as a biomarker and biomarker
Biphenylsulfonamides as effective MMP
Gnai3 Rat Pre
HMGCR inhibition stabilizes the glycolytic enzyme PKM2 to support the growth of renal cell carcinoma PMID 33905408
Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis PMID 26688060
Determination of triacylglycerols in butterfat by normal
MAP4K4 regulates forces at cell
Oil Red O (solution)
DL
Matrix protein of vesicular stomatitis virus targets the mitochondria, reprograms glucose metabolism，and sensitizes to 2
Synthesis and pharmacological evaluation of novel beta
G
Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair PMID 37973897
Specific inhibition of N
Resistance to aztreonam
Maz
Synthesis, cytotoxicity, and structure
NDUFAF3 Human Pre
RSK1 dependency in FLT3
Carbonyl cyanide 4
Survivin
MCE
FGD5 Human Pre
ALK
ALK
THAM
Supplementation with Eupatilin during In Vitro Maturation Improves Porcine Oocyte Developmental Competence by Regulating Oxidative Stress and Endoplasmic Reticulum Stress PMID 38338092
Sequential activation of multiple persistent inward currents induces staircase currents in serotonergic neurons of medulla in ePet
Structures of C3b in complex with factors B and D give insight into complement convertase formation PMID 21205667
Potent Antimalarials with Development Potential Identified by Structure
Cure of acute myelocytic leukemia in adults a reality PMID 2201825
R715 185052
TTR stabilizer L6 881290
Ncam2 Mouse Pre
2’
CRBN ligand
HDAC6
Azaconazole
(±)
Reuterin 2134
THLE
2,5
Ciamexone
BAG2
Defb1 Mouse Pre
Opemalirsen sodium scrambled negative control
Dammarane glycosides from the root of Machilus yaoshansis PMID 22779787
Fmoc
(
The insulin
5
Epithienamycin B 65376
EC0652
Effect of 6
Phrenosine 586
Prejunctional beta
GAP
Tozuleristide
ICI
MD1
CGP6809
CGP
Discovery of novel dihydroimidazothiazole derivatives as p53
Nutlin
Snail1
MZR
Rehmaglupentasaccharide B
MCE
BD
15
HSF1
Structure of potassium channels PMID 26070303
Metazosulfuron 868680
Supramolecular Peptide Nanofiber Hydrogels for Bone Tissue Engineering From Multihierarchical Fabrications to Comprehensive Applications PMID 35128831
Vezf1
Biotin
Chemically modified Pseudomonas species Cholesterol Esterase
Ppid
Anti
FNDC5
Immunosuppressant
ADAM8
MOFs
2,6
Fmoc
GAP 214
Sulfatrozole 13369
vasodilating agent
Boc
β Amyloid(28
Citreoindole 138655
Propargyl
Panc0203
Computational Design of CYP102A1 Variants for Biosynthesis of a Next
Avenanthramide L
Ncam2 Rat Pre
MCE
D
Tetradecyl
Design, Synthesis, and Biological Evaluation of NAP Isosteres A Switch from Peripheral to Central Nervous System Acting Mu
Serological analysis of allergic components of house dust mite provides more insight in epidemiological characteristics and clinical symptom development in North China PMID 37180108
Cynandione A and PHA
Ercc2
含 NAC alpha 域（NACAD）基因
MAP3K12 结合抑制蛋白 1（MBIP）基因
SUMF2 Human Pre
钙蛋白酶 15（CAPN15）基因
nNOS
Apba2
Fmoc
丝氨酸掺入子 3（SERINC3）基因
monkey FAP
Ppic Rat Pre
Ganoderic acid LM2 508182
Raddeanin A down
Malondialdehyde as a candidate biomarker for bipolar disorder A meta
Insulin
Triiodothyronine potentiates angiogenesis
MCE
MCE
HSC mobilizer
Novel PROTAC probes targeting FOSL1 degradation to eliminate head and neck squamous cell carcinoma cancer stem cells PMID 39002513
ICAM
Lysosomal Fusion An Efficient Mechanism Increasing Their Sequestration Capacity for Weak Base Drugs without Apparent Lysosomal Biogenesis PMID 31947839
Fibroblast activation protein
ARHGEF3 Human Pre
4
9858
Boc
Dihydrosinapyl alcohol 20736
Let
The Inoculum Effect in the Era of Multidrug Resistance Minor Differences in Inoculum Have Dramatic Effect on MIC Determination PMID 29784837
Hypoxia inducible factor HIF1α elevates expression of mRNA capping enzyme during cobalt chloride
Salvianolic acid B targets MST1/2
The reprogramming impact of SMAC
Muscarinic toxin 3 873336
DOTA
A
VRK2 inhibition synergizes with PD
The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice PMID 23811455
IFNG
Mitoferrin 2 deficiency prevents mitochondrial iron overload
Antiproliferative effect of flavonoids and sesquiterpenoids from Achillea millefolium s.l. on cultured human tumour cell lines PMID 19107850
Enantioseparation of gantofiban precursors on chiral stationary phases of the poly
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade PMID 22645360
Yi
Suppressive effect of N
4
Inhibition of Hif1α prevents both trauma
ADAM15 蛋白, Human (HEK293, His, solution)
Edaravone attenuates cerebral inflammation by inhibiting mast cells degranulation via ROS/STIM1 signaling pathway in HIE model PMID 40394799
Seselin 523
Letrozole 112809
Targeting dependency on a paralog pair of CBP/p300 against de
UNC7467 2922283
Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3
Libvatrep (SAF312)
Demethyl
Glaucine inhibits breast cancer cell migration and invasion by inhibiting MMP
Activity of immunoproteasome inhibitor ONX
A Liposomal Formulation Enhances the Anti
IP6K2 Human Pre
6
TGF beta 1 抗体 (YA5515)（TGF beta 1 Antibody (YA5515)）
Inhibition of de novo lipogenesis targets androgen receptor signaling in castration
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B
Pituitary adenylate cyclase
Deer antler extract promotes tibia fracture healing in mice by activating BMP
SKI
Microvesicles derived from activated T cells promote human mast cell migration via the S1P1 receptor PMID 40743264
CK1α upregulates the IFNAR1 expression to prompt the anti
白细胞介素 23 亚基 α（Il23a）基因
eRF3a 抗体（eRF3a Antibody）
CM082, a novel angiogenesis inhibitor, enhances the antitumor activity of gefitinib on epidermal growth factor receptor mutant non
BI 2536, a potent and selective inhibitor of polo
Tolfenamic acid
Semisynthetic analogues of toxiferine I and their pharmacological properties at α7 nAChRs, muscle
The APP intracellular domain promotes LRRK2 expression to enable feed
HDAC8 Prevents Anthrax Lethal Toxin
Design, Synthesis, and Biological Evaluation of Piperazine and N
Itaconate ameliorates methicillin
The antibody zalutumumab inhibits epidermal growth factor receptor signaling by limiting intra
Promotion of angiogenesis in cerebral infarction by Tongqiao Huoxue Decoction through activation of glycolysis PMID 41074933
Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats PMID 21197621
EZH2 inhibition enhances the activity of Carboplatin in aggressive
Nesprin1 抗体 (YA1369)（Nesprin1 Antibody (YA1369)）
c
Discovery of CREBBP Bromodomain Inhibitors by High
Differential Optical Imaging of Antigen Presentation Machinery Using Molecular Optical Reporters PMID 40370186
Iso cephalomannine (异三尖杉宁碱)
Evaluation of NitroSpeed
(±)
Alpha
A first
Targeting AXL induces tumor
A microchip flow
Phospho
Moexipril, a new angiotensin
Sirt7 protects against vascular calcification via modulation of reactive oxygen species and senescence of vascular smooth muscle cells PMID 39053861
GLUT4 activator 2 2761446
ZFAND6 Human Pre
Amlitelimab (FUT8
Targeting the 5
PVA (Mw 47000, 98
Antimicrobial susceptibility testing of Enterobacteriaceae determination of disk content and Kirby
Cd248a regulates pericyte development and viability in zebrafish PMID 40097701
Polystyrene nanoplastics induced learning and memory impairments in mice by damaging the glymphatic system PMID 39153278
CYM51010 (Standard)
BCKDK 抗体 (YA2737)（BCKDK Antibody (YA2737)）
Delivery of SAR 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (STZ) model of diabetic retinopathy (DR) PMID 20445119
MUC5AC motif peptide 244049
RBM3 Ameliorates Acute Brain Injury
Preclinical pharmacokinetics and metabolism of a novel prototype DNA
MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis PMID 40679030
Simepdekinra 2978700
MCE
Cd300e Rat Pre
HucMSCs
Prime assembly with linear DNA donors enables large genomic insertions PMID 40667017
Leucine aminopeptidase 3 a promising serum biomarker candidate for nonalcoholic steatohepatitis diagnosis PMID 37058753
MCE
AC
Diacylglycerol kinase as a possible therapeutic target for neuronal diseases PMID 24708409
6
五味子酯甲
LUF5834 333962
Effect of cyclic RGD peptide on cell adhesion and tumor metastasis PMID 1710455
ZIC1 Human Pre
Inhibition of intrinsic protein tyrosine kinase activity of EGF
Methylamino
Naringenin inhibits autophagy and epithelial
CRBN ligand
Mexiprostil 88980
Ebelactone A 76808
The novel nucleoside analog R1479 (4'
FGTI
Light signal regulates endoreduplication and tomato fruit expansion through the SlPIF1a
Targeted VEGFA therapy in regulating early acute kidney injury and late fibrosis PMID 37055531
STAT3 palmitoylation initiates a positive feedback loop that promotes the malignancy of hepatocellular carcinoma cells in mice PMID 38051779
BFE
Sodium 4
GLK7
Mucopolysaccharidoses I and II Brief Review of Therapeutic Options and Supportive/Palliative Therapies PMID 33344633
Neuroactivity of the naturally occurring aporphine alkaloid, roemerine PMID 33025828
Discovery and Optimization of Chromeno[2,3
E5700
Q817
ALK protein
modified nucleobases
ADMET properties
Termitomycamide E 1177258
AGT182
4,4'
In vitro and in vivo activities of E5700 and ER
IQSEC1 Human Pre
DLX2 Human Pre
DSPS
Sirt1
Dermaseptin
Phenol
Homobotcinolide 177182
Pharmacological validation of a mouse model of l
Ritipenem 84845
Bioassay, determination and separation of enantiomers of atenolol by direct and indirect approaches using liquid chromatography A review PMID 28905405
Pioglitazone Ameliorates Atorvastatin
Phallacidin 26645
Unintended consequences
1,4
Synthesis, molecular modeling and biological evaluation of 2
4'
Tubule
YH18968, a Novel 1,2,4
c
Oxathiapiprolin 1003318
LY86 Human Pre
Wenhua Juanbi Recipe Attenuates Rheumatoid Arthritis via Inhibiting miRNA
long chain
Chartarlactam A
碳酸酐酶
BVT
Conofurin
Rapid Screening of Potential Phosphodiesterase Inhibitors from the Roots of Ilex pubescens Hook. et Arn. Using a Combination of Ultrafiltration and LC
Rezafungin acetate 1631754
Gageotetrin B
Roles of Sulfur Metabolism and Rhodanese in Detoxification and Anti
(S)
Reveromycin D 144860
Benzylideneacetone, an immunosuppressant, enhances virulence of Bacillus thuringiensis against beet armyworm (Lepidoptera Noctuidae) PMID 18330113
Suppression of microtubule dynamics by binding of cemadotin to tubulin possible mechanism for its antitumor action PMID 9860873
Antitumor agent
Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid NHANES 2005
Valrocemide 92262
Phospho
ERα degrader 14
Rehmaglupentasaccharide A
CGP
Generation, optimization and characterization of novel anti
1
MCE
HMG chromosomal proteins in development and disease PMID 17169561
GLP
Sannamycin E 73051
NCAM2 Human Pre
16G2
Adiponectin Signaling Regulates Urinary Bladder Function by Blunting Smooth Muscle Purinergic Contractility PMID 39554160
Anticancer agent 309
Deacetyldiltiazem
VPS52 Human Pre
FG 488 DHPE 438476
Dissecting infectious bronchitis virus
A First
BET1L Human Pre
Globular adiponectin inhibits osteoblastic differentiation of vascular smooth muscle cells through the PI3K/AKT and Wnt/β
Cholyl
NCAM2
3,4
Dner
含 delta/notch 样 EGF 重复（DNER）基因
Ppic
Scutellarin attenuates keloid fibroblast progression by targeting EGFR/PI3K/AKT signaling An integrated network pharmacology and in vitro experimental study PMID 41067505
含 splA/ryanodine 受体结构域和 SOCS 盒 3（SPSB3）基因
BM635 mesylate 2703867
5′
Automated, High
Saikosaponin B1 and Saikosaponin D inhibit tumor growth in medulloblastoma allograft mice via inhibiting the Hedgehog signaling pathway PMID 35171398
Rps15 Rat Pre
Antitumor agent
PGMI
KRAS ligand 5 3043896
2
PEG 12 cetostearyl ether 13149
LRH
Erbstatin 100827
Bis
Hydrophobic drug adsorption loss to syringe filters from a perspective of drug delivery PMID 30529169
GSK4418959 (enantiomer) 3064599
The clinical use of granulocyte
AN
Neu5Troc[1Me,4789Ac]α(2
Development of isoform selective PI3
A selective prostaglandin E2 receptor subtype 2 (EP2) antagonist increases the macrophage
Empagliflozin alleviates hepatic ischemia
Lack of L
4
Mitoxantrone Combined with Engineered TRAIL
HA1/Hemagglutinin 蛋白, H3N2 (ACS71642, HEK293, His)
A nuclear
The in vitro pharmacology of ZM 241385, a potent, non
N
IGF2 蛋白, Human (Biotinylated, HEK293, Fc
Homoplantaginin 17680
CRBN ligand
Antagonist binding profiles of five cloned human muscarinic receptor subtypes PMID 1994002
Carbapenems past, present, and future PMID 21859938
CRBN ligand
The synergistic antitumour effect of Carrimycin combined with 5
Precision
Broussochalcone A 99217
Rrm1
Influence of hydralazine on the pharmacokinetics of tauromustine (TCNU) in mice PMID 1558786
Fmoc
Rationally designed high
CRBN ligand
Ginsenoside Rh2 enhances the antitumor immunological response of a melanoma mice model PMID 28356946
SREBP1
Stearate
Lycorine hydrochloride selectively inhibits human ovarian cancer cell proliferation and tumor neovascularization with very low toxicity PMID 23376478
A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic
15(S)
Synthesis and anti
Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor PMID 35158113
Cantharidic acid disodium 1465
PROTAC PI3Kα/δ degrader
6
LR
hsa
Fluorescein
Isoegomaketone 34348
Prometon
A new perspective for schizophrenia TAAR1 agonists reveal antipsychotic
TGF
Antitumor agent
YY2/BUB3 Axis promotes SAC Hyperactivation and Inhibits Colorectal Cancer Progression via Regulating Chromosomal Instability PMID 38682484
Butylcycloheptylprodigiosin
干扰素 α 和 β 受体亚基 2（Ifnar2）基因
In vitro and in vivo study of an albumin
(20S)
Cysteine and Folate Metabolism Are Targetable Vulnerabilities of Metastatic Colorectal Cancer PMID 33498690
Targeted ZnO@CuEA Nanoplatform for Cuproptosis
Autophagy alleviates the decrease in proliferation of amyloid β1‑42‑treated bone marrow mesenchymal stem cells via the AKT/mTOR signaling pathway PMID 30896831
CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets PMID 18227348
M4K2306 3034840
Discovery of fused benzimidazole
PDLIM1 Inhibits Tumor Metastasis Through Activating Hippo Signaling in Hepatocellular Carcinoma PMID 31509262
AM
L
GKT136901 hydrochloride 1254507
FQI2
Urolithin A exerts anti
PROTAC for Bruton's tyrosine kinase degradation alleviates inflammation in autoimmune diseases PMID 39107285
LY164846 92218
Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii a new class of potent anti
Posaconazole
Optimization of a small molecule probe that restores e
IRAK4 modulator
Rovelizumab 339086
Synthesis and evaluation of antimycobacterial activity of riboflavin derivatives PMID 34242760
SMAD3 promotes expression and activity of the androgen receptor in prostate cancer PMID 36727462
Acute and subacute oral toxicity of propylene glycol enantiomers in mice and the underlying nephrotoxic mechanism PMID 34461418
共956页
首页
上一页
827
826
825
824
823
822
821
820
819
818
817
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新