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HDAC6
Ki20227 (Standard)
Design and Synthesis of Novel Antimicrobial Agents PMID 36978495
HDAC6 degrader
Obscurolide A1
Reveromycin D
Rubrolone
Real
Acid Phosphatase (ACP), Sweet Potato (Non
Pladienolide A
Dihydromocimycin
Kinamycin B
Elmycin D
Feigrisolide C
Epithienamycin B
6
Boromycin
6
Leucomycin A1
Okilactomycin
Sannamycin E (桑那霉素)
Bis
MCE
2,3
CN016
JS 04
Teneligliptin inhibits lipopolysaccharide
(R)
Rat hemopexin (大鼠血红素)
Methylprednisolone
Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus PMID 9267779
Oxidative stress and DNA damage in earthworm (Eisenia fetida) induced by triflumezopyrim exposure PMID 33049500
Suppression of NSCLC progression via the co
MCE
Esculentoside R
Mal
基质相互作用分子 2(STIM2)基因
Klf6
cycloSal
Context
Treprostinil indirectly regulates endothelial colony forming cell angiogenic properties by increasing VEGF
L 696229 135525
MCE
28
BMS453 (Standard)
C10 Ceramide
The Influence of N
C30
Distearin (Stearic diglyceride)
Panaxatriol (人参三醇)
C32 Ceramide
Phrenosine (C24 0(2R
GLX481369
Boc
Amino
Antitumor agent
mmu
Functionally
5
Osmanthuside B6 (桂叶苷B6)
Papaya extract
Ppic Mouse Pre
Synthesis and activity of novel tetrazole compounds and their pyrazole
β
CD314/NKG2D 抗体 (YA4678)(CD314/NKG2D Antibody (YA4678))
Hydroxy
The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex PMID 38514807
Parkin 抗体(Parkin Antibody)
Assessing CFTR Function and Epithelial Morphology in Human Nasal Respiratory Cell Cultures A Combined Immunofluorescence and Electrophysiological Study PMID 40806745
BAY
Flavonoid Derivative DMXAA Attenuates Cisplatin
GVLSNVIGYLKKLGTGALNAVLKQ
Tetranorclerodanes and clerodane
Spag4 Rat Pre
Domperidone review of pharmacology and clinical applications in gastroenterology PMID 17488253
hsa
Discovery of a Nur77
PHACTR1 Human Pre
Tonabersat
Diprovocim
Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di
2
AK8 抗体 (YA9526)(AK8 Antibody (YA9526))
Chronic high
cAMP 反应元件结合蛋白 3(CREB3)基因
2
IFRD1 抗体 (YA2507)(IFRD1 Antibody (YA2507))
Ginkgolic Acid Suppresses Nasopharyngeal Carcinoma Growth by Inducing Apoptosis and Inhibiting AKT/NF
Raltegravir (Standard) (雷特格韦 (标准品))
Folic acid
WRN inhibitor 13 2923009
The antileukemia activity of a human anti
GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors PMID 19859563
FoxO1 Regulates Neuropeptide Y and Pro
DHTP 1620225
18 1 Glutaryl PE
Label
BRD4 Inhibitor
Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol PMID 18160712
Antithrombotic effects of sulfinpyrazone in animals influence on fibrinolysis and sodium arachidonate
Boc
In vitro cytotoxicity assessment of ruxolitinib on oligodendrocyte precursor cell and neural stem/progenitor cell populations PMID 39209271
Reprogramming of Myeloid Responses to Volumetric Muscle Loss via Engineered Protein Nanoparticles PMID 40788769
lathosterol
Acid Phosphatase, Prostatic (ACP/PAP) (ACP, PAP, Acid Phos, 5'
The ABCB1 and ABCG2 efflux transporters limit brain disposition of the SYK inhibitors entospletinib and lanraplenib PMID 38527694
Parkin 抗体 (YA5898)(Parkin Antibody (YA5898))
Dnmt3b 抗体 (YA1806)(Dnmt3b Antibody (YA1806))
Glycosylation on breast cancer cell surface promotes the internalization and enhances therapeutic efficacy of cationic antimicrobial peptide L
The lysosomal trafficking of acid sphingomyelinase is mediated by sortilin and mannose 6
Biotin
An autophagic process is activated in HepG2 cells to mediate BDE
UBE2E2 Human Pre
SCD1 抗体 (YA1163)(SCD1 Antibody (YA1163))
MCRS1 Human Pre
Segregation of receptor and ligand regulates activation of epithelial growth factor receptor PMID 12646923
Rad21 抗体 (YA3546)(Rad21 Antibody (YA3546))
Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD
NCGC00244536 (Standard) (KDM4B Inhibitor B3 (Standard))
AMHR2/MISRII 蛋白, Human (Biotinylated, HEK293, His
Repurposing the antihistamine terfenadine for antimicrobial activity against Staphylococcus aureus PMID 25238555
MEF2A 抗体 (YA3324)(MEF2A Antibody (YA3324))
Myclobutanil worsens nonalcoholic fatty liver disease An in vitro study of toxicity and apoptosis on HepG2 cells PMID 27693777
CSF1R
Identification of Dihydrofuro[3,4
Novel FoxO1 inhibitor, JY
MCE
RN941 1360055
Efficacy of chitosan, a natural polysaccharide, against Cryptosporidium parvum in vitro and in vivo in neonatal mice PMID 30237052
α
Multiprotein bridging factor
Rapid membrane effect of estrogens on stimulation of corticotropin
Simeton
Ppm1g
MCE
Melithiazole K
Novel 5
Ac
Preparation and Characterization of an Engineered FGF1 Conjugated to 161Tb for Targeting of FGFRs PMID 39989790
IGFBP
Nicorandil inhibits TLR4/MyD88/NF
Methyltransferase
Acute pancreatitis recent advances through randomised trials PMID 28838972
Antibacterial activities of cefprozil compared with those of 13 oral cephems and 3 macrolides PMID 7726528
Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment PMID 28129639
1
3’
泛素结合酶 E2 H(UBE2H)基因
SNAP 94847 487051
PROTAC EZH2 Degrader
Exosomes from tumor
Ivabradine Ameliorates Cardiac Diastolic Dysfunction in Diabetic Mice Independent of Heart Rate Reduction PMID 34239443
原发性尿道癌
A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization PMID 17029007
PFI
Foxp3 inhibits PCV2 replication by reducing the ATPase activity of Rep PMID 40112692
Opemalirsen (AZD2373, ION
Anti
A novel experimental heme oxygenase
Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti
MOPS sodium salt 71119
SARM1
Mal
3
The combination of metformin and 2
Coryanthe yohimbe extract
Methyllycaconitine (MLA,甲基牛扁亭)
The role of the immune system in hexachlorobenzene
NGD
Spectroscopic investigation on the interaction of 3,7
Analgetic and anticonvulsant activity of some 2and 4
Effect of hCMSCs and liraglutide combination in ALI through cAMP/PKAc/β
Frizzled
Mechanism of tumor cell killing by HO
3’,5’
Cronobacter sakazakii induces necrotizing enterocolitis by regulating NLRP3 inflammasome expression via TLR4 PMID 32209170
Discovery of water
5
N
1,2,3
Epha10
Ajmalicine hydrochloride 4373
PD
热激蛋白家族 B (小) 成员 7(HSPB7)基因
Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID
Cy 5 hydrazide 1427705
GSK 1842799 hydrochloride
3
Necopidem 103844
The chemistry of rubradirin. III. The rubradiric acids and the structure of rubradirin PMID 541275
acetophenone dimer
Tranilast antagonizes angiotensin II and inhibits its biological effects in vascular smooth muscle cells PMID 9125291
DCC
Morinamide 952
Organoruthenium Glycomimetics Exhibit High Selectivity and Nanomolar Affinity for Human Galectin
Allantoin, (
N
Z
Cytoprotective effects of 4,6
On shockwave propagation and attenuation in poly(ethylene glycol) diacrylate hydrogels PMID 33752092
Docosanoic acid
Evaluation of Dual 5
EGC
STAT3 activation by catalpol promotes osteogenesis
2
Protective effects of HFE7A, mouse anti
Oleanolic acid
mouse thymocytes
Propargyl
Splenic TNF
Prostasin/PRSS8 蛋白, Rat (HEK293, His)
Low
Boc
NN6020
APBA1 Human Pre
Tenofovir maleate 1236287
OP3136
WALP
Cucurbitacin B suppresses malignant progression of oral leukoplakia via ferroptosis
ELQ
Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA PMID 24755925
Legumain correlates with neuroblastoma differentiation and can be used in prodrug design PMID 28994241
Tangeretin Inhibits BACE1 Activity and Attenuates Cognitive Impairments in AD Model Mice PMID 35084179
Fibroblast growth factor receptor modulators employing diamines with reduced phospholipidosis
N
The inner nuclear membrane protein LEMD3 organizes the 3D chromatin architecture to maintain vascular smooth muscle cell identity PMID 41044070
Selection for vancomycin resistance in clinical isolates of Staphylococcus haemolyticus PMID 2295858
NAMPT activator
10
Glp
The modulation of cholecystokinin receptor 1 in the NAc core input from VTA on METH
6
Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells implications for glaucoma pathogenesis PMID 23360789
Quaternium15
Arg
Sibiricose A4 241125
Predictive Significance of Glycosyltransferase
Agranulocytosis associated with cocaine use
Effect of hycanthone administered in vivo upon the incorporation of radioactive precursors into macromolecules of Schistosoma mansoni PMID 6192338
PDE
4
Teglicar 250694
CRBN ligand
5M Ammonium acetate Buffer,Sterile (无菌5M 醋酸铵溶液)
ABCG2 蛋白, Human (HEK293)
Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK
COX
O
Metabolism of myosmine in Wistar rats PMID 16079272
Liproxstatin
Aflatoxin G1
含三方基序 69(TRIM69)基因
Grn Mouse Pre
R243 688352
TGF
Nitro
AGN
The primary mechanism for highly potent inhibition of HIV
Thermolysin, Geobacillus stearothermophilus
Discovery of novel dual tubulin and MMPs inhibitors for the treatment of lung cancer and overcoming drug resistance PMID 39823807
Bretisilocin 2698331
Eotaxin
Propargyl
Inhibition of hypoxia
Anxiolytic and antidepressant effects of ACPA and harmaline co
Chemerin/RARRES2 蛋白, Human (HEK293, His)
A Phase 3 Trial of Difelikefalin in Hemodialysis Patients with Pruritus PMID 31702883
II 型胶原α1 链(COL2A1)基因
STAT3 as a potential therapeutic target in ALDH+ and CD44+/CD24+ stem cell
甾醇调节元件结合转录因子 1(SREBF1)基因
Interleukin
KUNG29 1887032
钙依赖性分泌激活因子(CADPS)基因
Polysaccharides Produced by the Mushroom Trametes robiniophila Murr Boosts the Sensitivity of Hepatoma Cells to Oxaliplatin via the miR
Saturated fatty acids induce lipotoxicity in lymphatic endothelial cells contributing to secondary lymphedema development PMID 40759794
A novel homozygous ISG15 missense variant leads to severe inflammatory skin lesions, interstitial pneumonia, and basal ganglia calcifications in a Chinese infant with ISG15 deficiency PMID 40318816
[Asn18] Endothelin
Panaxatriol (Standard) (人参三醇 (标准品))
HIF
β
MDEKMLVLWVVALS(Gly
Inhibition of c
Aliskiren hydrochloride 173399
MCE
GTx
(Rac)
核糖体结合因子 A(RBFA)基因
Wee1 inhibition by MK1775 potentiates gemcitabine through accumulated replication stress leading to apoptosis in biliary tract cancer PMID 37659202
NS2B/NS3
Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors PMID 34971423
Citric acid triammonium 3458
MULTIPLEX PCR ASSAY FOR DETECTION OF HUMAN SOMATOTROPIN AND INTERFERON ALPHA2b GENES IN PLANT MATERIAL PMID 26214899
Elastin from bovine 9007
Acetoacetic acid induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes PMID 27692001
5
PRKDC promotes hepatitis B virus transcription through enhancing the binding of RNA Pol II to cccDNA PMID 35468873
PPIC Human Pre
钙库操纵的钙内流相关调节因子(SARAF)基因
gZiPro construct
E2F 转录因子 3(E2F3)基因
细胞间粘附分子 3(ICAM3)基因
激酶插入域蛋白受体(Kdr)基因
肌球蛋白 X(MYO10)基因
MYC 相关锌指蛋白(MAZ)基因
黄嘌呤脱氢酶(XDH)基因
Cucurbituril (Standard)
Curcumin inhibits the growth of triple
Defb1
Krt19
辅酶 Q8B(COQ8B)基因
Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance PMID 35947955
1
Epoxygenase Cyp2c44 regulates hepatic lipid metabolism and insulin signaling by controlling FATP2 localization and activation of the DAG/PKCδ axis PMID 38743615
MDL 19205 84490
Isothiafludine 960527
Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design PMID 26307417
Synthesis of quinolinomorphinan
Therapeutic efficacy of povidone
HPRT promotes proliferation and metastasis in head and neck squamous cell carcinoma through direct interaction with STAT3 PMID 33340493
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3
Xa inhibitor edoxaban ameliorates hepatic ischemia
ALG
[Biomanufacturing of monoclonal antibodies] PMID 31903930
Chartarlactam A
S
NSCLC cells sustain phase separation of cytoplasmic membrane
Design, synthesis and biological evaluation of novel 4
Epibetulinic acid 38736
Epoxyazadiradione 18385
HE4
RNASEH1 Human Pre
Bergamottin is a competitive inhibitor of CYP1A1 and is antimutagenic in the Ames test PMID 22705772
Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure
C
CD133/PROM1 Protein
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone
G Protein
AR ligand
(1R,2S)
A Two Amino Acid Duplication, L167E168, in the Ω
N
CLDN14 Human Pre
Mechanism of dsDNA binding, enzyme inhibition, antioxidant activities, and molecular docking studies of taxifolin, daidzein, and S
Galnon TFA (Standard)
TYK2 licenses non
PD
hIgG
26973
Crocin Impurity 1 91740
Biomimetic Microparticles with Myocardial and Endocardial Integration for Drug Toxicity Studies PMID 40198907
Combinatorial functionomics identifies HDAC6
SHP2 Targets ITK Downstream of PD
Superstable lipid vacuoles endow cartilage with its shape and biomechanics PMID 39787221
Uric acid promotes aortic valve calcification via mediating valve interstitial cell osteogenic differentiation and endothelial dysfunction PMID 40100089
Synthesis and SAR studies of novel 1,2,4
Passage through the Ocular Barriers and Beneficial Effects in Retinal Ischemia of Topical Application of PACAP1
Heterogeneous Responses to High
Inhibitors of phosphatidylinositol 3'
PKPD modeling of the inoculum effect of combined ceftazidime/avibactam and colistin against KPC
Antibody
CA
From irreversible to reversible covalent inhibitors Harnessing the andrographolide scaffold for anti
Rewiring the fusion oncoprotein EWS/FLI1 in Ewing sarcoma with bivalent small molecules PMID 40166278
Mitochondrial fatty acid oxidase CPT1A ameliorates postoperative cognitive dysfunction by regulating astrocyte ferroptosis PMID 39725377
DLL3 Human Pre
Association of IL
Tubulin inhibitor 22 3033038
CRBN ligand
NH
Propargyl
Taurochenodeoxycholic acid induces NR8383 cells apoptosis via PKC/JNK
A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway PMID 28165738
The Roles of IL
Tssk2 Mouse Pre
Amorfrutin A inhibits TNF
Effects of Different Types of Recombinant SARS
Broad
Neuronal responses of the nucleus tractus solitarius to oral stimulation with umami substances PMID 1886951
Identification of a Novel Peptide from β
Alpha
A µ
4
Discovery of novel deoxyvasicinone derivatives with benzenesulfonamide substituents as multifunctional agents against Alzheimer's disease PMID 38052155
Rad21 抗体 (YA2985)(Rad21 Antibody (YA2985))
Targeting the immunoproteasome in hypothalamic neurons as a novel therapeutic strategy for high
Susceptibility of Elizabethkingia spp. to commonly tested and novel antibiotics and concordance between broth microdilution and automated testing methods PMID 33258923
hsa
Effect of papaverine and dihydroergotoxine mesylate on cerebral microflow, EEG, and pO2 in oligemic hypotension PMID 618777
IL21R
Boc
16 0
DNA
A comparative study of the efficiency of mitochondria
METTL1 mediates PKM m7G modification to regulate CD155 expression and promote immune evasion in colorectal cancer PMID 39741310
GSK3 alpha 抗体 (YA4055)(PBS only)(GSK3 alpha Antibody (YA4055)(PBS only))
GDCNF
Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group Access to Cyclopentenes and Indenes PMID 34747130
Synergistic anti
Influenza A virus
Small, non
Rupatadine protects against pulmonary fibrosis by attenuating PAF
Two new triterpenes isolated from Maytenus guangxiensis C. Y. Cheng et W. L. Sha and their antiproliferative activities PMID 35014566
Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors A structure
ZXH
Sinomenine
c
U
Effects of excess dietary l
Sulfasalazine combined with anti
Spermine enhances antiviral and anticancer responses by stabilizing DNA binding with the DNA sensor cGAS PMID 36724787
[D
In Vivo Reprogramming of Tissue
Localization of cholecystokinin A and cholecystokinin B
Suppression of caspase
CDK9 inhibition induces epigenetic reprogramming revealing strategies to circumvent resistance in lymphoma PMID 36998071
ONO
Cdr2l Rat Pre
Sennoside A Modulates the Ferroptosis and Immune Evasion of Oral Squamous Cell Carcinoma Cells Through Inhibiting the NF
Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation PMID 28767222
PR
CRBN ligand
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C
Identification of Collagen
The therapeutic potential of a series of orally bioavailable anti
High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner PMID 24823908
HSD17B13
The MAPK/ERK signaling pathway involved in Raddeanin A induces apoptosis via the mitochondrial pathway and G2 phase arrest in multiple myeloma PMID 39580496
ABT
5
Tumor vascular endothelial cells promote immune escape by upregulating PD
METTL3 regulates Ambra1 expression in an m6A
KRAS G12C inhibitor 56 2749963
Healthy Plasma Exosomes Exert Potential Neuroprotective Effects against Methylmalonic Acid
SB 242235 193746
MCE
Muscle
Zectivimod 1623066
Naringin induces autophagy
ZDZ
Number 2 Feibi Recipe Inhibits H2O2
Bioassay
Coumarins from Seseli devenyense Simonk. Isolation by Liquid
N
Jagged1
Ammonia regulates chicken tracheal cell necroptosis via the LncRNA
JNJ
Effects of quinoline and 8
HSGN
The effect of dantrolene sodium on rat skeletal muscle in relation to the plasma concentration PMID 421731
Lomerizine 101477
Discovery of Two Novel Antiplatelet Clinical Candidates (BMS
MiR
A randomized, double
Screening of anti
HOCPCA 867178
SET 绑定因子 2(SBF2)基因
MCE
Ginsenoside CK modulates glucose metabolism via PPARγ to ameliorate SCOP
BRM/BRG1 ligand 1 1893977
DMT
LDHA
cis
LZTS3/TAGLN Suppresses Cancer Progression in Human Colorectal Adenocarcinoma Through Regulating Cell Proliferation, Migration, and Actin Cytoskeleton PMID 37806182
Selective DOT1L, LSD1, and HDAC Class I Inhibitors Reduce HOXA9 Expression in MLL
Bifunctional HDAC and DNMT inhibitor induces viral mimicry activates the innate immune response in triple
Inositol phosphate biochemistry PMID 1323235
CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB
MCE
Antitumor effect of erythromycin in mice PMID 7875024
Discovery of AK
CPT1A/HIF
Atranol 526
Modified (
D
NSC134754
[A comparison of therapeutic effectiveness between rifamdin
Cancer Cells Show Higher Sensitivity to Melatonin
Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors PMID 26370839
CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses PMID 26261308
Localization of xanthine oxidase in crystalline cores of peroxisomes. A cytochemical and biochemical study PMID 3443108
丝氨酸羧肽酶 1(SCPEP1)基因
8'
A Bio
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition PMID 35444283
MCE
Proroxan hydrochloride 33025
9(S)
Koumine, Humantenine, and Yohimbane Alkaloids from Gelsemium elegans PMID 26103517
A structure
Methyl dodecanoate
Design, synthesis and biological evaluation of thieno[3,2
Small
Recent advances in urocanic acid photochemistry, photobiology and photoimmunology PMID 18528548
Combined BRAF, MEK, and CDK4/6 Inhibition Depletes Intratumoral Immune
MCE
10
Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis PMID 36774517
Bonaphthone
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