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Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model PMID 34546973
CRBN ligand
2′
Sceptrin dihydrochloride
17 0 Cyclo acid
quaternary ammonium compound
Calpain
CircMALAT1 promotes cancer stem
Quantitative Evaluation of the Effect of Antigen Expression Level on Antibody
Adipic acid dihydrazide (Adipodihydrazide)
Sulfatrozole (磺胺曲唑)
3
Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons assessment of the protective effects of glycoursodeoxycholic acid PMID 19818102
MCE
3′,5′
BRAP 抗体 (YA5285)（BRAP Antibody (YA5285)）
trans
Melitidin
TAK
Nutlin 1
Asthma phenotypes and T
PBOX 6
stereoselectively
GPR35 agonist
Piroxicam
ACP1
Antimicrobial effects of N alpha
U
Deciphering the Role and Mechanism of Decidual Monocyte
Psidial A 1207181
2
Slc4a4
ASPA 抗体 (YA6467)（ASPA Antibody (YA6467)）
MCE
E3 ligase Ligand 31 2357114
Effect of porcine gastric inhibitory polypeptide on beta
Poly(amidoamine) dendrimer
FFAR1/FFAR4 agonist
α
Hexose
Zinc pyrithione exposure compromises oocyte maturation through involving in spindle assembly and zinc accumulation PMID 35278989
Long noncoding RNA ANRIL alleviates hypoxia
Cross
Aptamer Functionalized Liposomes Co
(S)
Low BOK Expression Promotes Epithelial
F6524
(1R,2R,4R)
Amiodarone
UCM 608
(R)
Nigakinone
Icalcaprant 2227384
H
S
FL
Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia
Fmoc
A
2
Eprozinol
DL 473
In vivo enhancement of murine natural killer cell activity by 7
High
7760
MCE
SCF 蛋白, Rat (HEK293)
ZD7288 (Standard)
DTB
Bruceine G
AY 25674
LJ
GK
Wild yam extract
Crabp1
BRAFV600E/ABL2
Repositioning the over
Pxn
跨膜丝氨酸蛋白酶 11A（TMPRSS11A）基因
8
Mutant HRAS as novel target for MEK and mTOR inhibitors PMID 26544513
CADPS
HDAC11
The influence of dihydroergotoxine mesylate on the low
PCSK9 Expression in Vascular Smooth Muscle Cells Role of Insulin Resistance and High Glucose PMID 39940773
Z
BNP(7
Dhcr7 Mouse Pre
3,4
Monolauryl phosphate 2627
JAK1/CDK7
Cellubrevin and synaptobrevins similar subcellular localization and biochemical properties in PC12 cells PMID 7698987
Design, synthesis, and biological evaluation of 2
C19
RNF186 regulates EFNB1 (ephrin B1)
Alternative products in the reaction of 2
细胞视黄酸结合蛋白 1（CRABP1）基因
Snap25
Lysosome
Lauryl oleate (Dodecyl oleate)
同种异体移植炎症因子 1（AIF1L）基因
CP21R7 (Standard)
A novel frameshift variant in the TSPAN12 gene causes autosomal dominant FEVR PMID 35417085
Vertical Pathway Inhibition Overcomes Adaptive Feedback Resistance to KRASG12C Inhibition PMID 31776128
Ntn1
Pharmacologic characterization of the antiinflammatory properties of a new dual inhibitor of lipoxygenase and cyclooxygenase PMID 3107354
3'
Lnc
Fluocinonide 356
Fndc5
MCE
Col2a1
(S)
L
MCE
Three 11,12
DMQ10
Bioactive triterpene saponins from the roots of Phytolacca americana PMID 18177012
The marine
Potassium tert
Tanshinoic acid A 2569515
UQ10
DHCR7 Human Pre
COQ7
EGFR/VEGFR2
3
Glutamine Deficiency Promotes PCV2 Infection through Induction of Autophagy via Activation of ROS
1,4
Ravulizumab 1803171
Dhcr7 Rat Pre
lung cells
Synthesis and in vitro evaluation of novel tetrazole embedded 1,3,5
Monolauryl
Esculentoside L
TRPM8 antagonist 3 2102179
Synthesis and antitumor activity of novel quinazoline derivatives containing thiosemicarbazide moiety PMID 22749192
Pharmacology of MK
pathological tau
Drug discrimination A versatile tool for characterization of CNS safety pharmacology and potential for drug abuse PMID 27235786
DL
Magnesium dodecyl
Mpa(Trt)
(E)
Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy PMID 38016957
GABARAPL1 Exerts Regulatory Effects on Hypoxia
Adrenomedullin (porcine) 912862
KAT2B inhibits proliferation and invasion via inactivating TGF
Bifunctional thiosialosides inhibit influenza virus PMID 24374271
Z
Ginsenoside Rg1 Reduced Microglial Activation and Mitochondrial Dysfunction to Alleviate Depression
Triterpenoids with antiproliferative activities from the twigs and leaves of Melaleuca linariifolia PMID 32608251
D
MRGPRX1 agonist 1 2377379
Pharmacologic Evidence for a Putative Conserved Allosteric Site on Opioid Receptors PMID 29233847
SP
CRBN ligand
urokinase
Pristanic acid 1189
Trimethylbenzoquinone 935
GypenosideZ
Fmoc
Design, Synthesis and Biological Evaluation of Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors PMID 41320919
Scale down and optimized automated production of [68Ga]68Ga
Solid
diethyl ether extraction
Binding techniques to study the allosteric energy cycle PMID 22052482
Boc
Highly potent activity of isopulegol
Sex differences in heat shock protein 72 expression and localization in rats following renal ischemia
Bonaphthone 6954
Fmoc
A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite
The effect of RPR 102341 on theophylline metabolism and phenacetin O
Loncipoetin alfa
Octyl decyldimethyl ammonium chloride 32426
Bifluranol, a novel fluorinated bibenzyl anti
Pharmacological Activation of GPR68 Attenuates Ferroptosis in Spinal Cord Ischemia/Reperfusion Injury Through PI3K/Akt
TIFA
Fmoc
Combined Fmoc
Pxn Mouse Pre
MCE
Parthenin 508
MLS
R6G
Bifluranol 34633
Novel p38 mitogen
thioester bond
COQ2 Human Pre
3,5
Antileishmanial agent
ESI
Reduction in Secretion of Very Low Density Lipoprotein
粘附 G 蛋白偶联受体 G7（ADGRG7）基因
T7 peptide
p
Brd8
Dna2
Discovery of novel 1,8
Ipsalazide (伊普柳氮)
FCGR1A
28
DRV
Isolation and characterization of multiple variants of recombinant human interleukin 4 expressed in mammalian cells PMID 3260592
The Effect of Salvianolic Acid A on Tumor
Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells PMID 34172095
Cichoric Acid Reverses Insulin Resistance and Suppresses Inflammatory Responses in the Glucosamine
2
PFOS facilitates liver inflammation and steatosis An involvement of NLRP3 inflammasome
Sequential Targeting Chondroitin Sulfate
Polymerization reactions
Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein
PPM1G
Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor PMID 8551343
FPL 52757 37467
TP53R175H mutation promotes breast cancer cell proliferation through CORO1A
A
p
The selective alpha7 nicotinic acetylcholine receptor agonist A
FPL52757
Rubradirin
CT/bone scans
FGF basic (93
DHRS11 Human Pre
(+)
Seclidemstat (Standard)
DKFZ
PU2049
DKFZ 251
DF
EC0652 1025066
CDD
Alpha
MBM
neuroblastoma
AgrA DNA binding
Oral fluoropyrimidine anticancer drug TS
Dichlorvos
PP48 2629270
Tyr1537
A
Galectin
Anticancer agent 294 1258392
DMA4
CXA101
Simultaneous determination and validation of oncrasin
3
Glucosamine sulfate potassium chloride (硫酸氨基葡萄糖氯化钾盐)
YRGDS Fibronectin Fragment 134282
developing kidney
(Thr4,Gly7)
Bovine primary chondrocyte culture in synthetic matrix metalloproteinase
bursting cell
Oxytocin receptors within the caudal lateral septum regulate social approach
Dimethyl 3,3′
1
Suppressing transthyretin production in mice, monkeys and humans using 2nd
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization PMID 39629501
KH
NE10064
Small molecule
EGFR
NR2F2
COLO 205
MAP3K12
HSD17B13
PRMT5
TBX5 Human Pre
Glycodeoxycholic acid
RPR
SPB
SJ6986
Sudan IV
GSK
AG
VDR agonist2
BA
Myr
Setoxaximab 1351470
RNA MTase
JG
Nilotinib monohydrochloride monohydrate 923288
PFM046 3053859
Acoziborole 1266084
Ceforanide
Methyl 2,3,5
ABCA1 inducer 2 2451589
LAAVSDLNPNAPR 415684
BACE1
MIP
GPLGIAGQ 109053
SKF 385
A549 cell
alcohol use disorder
ABCA1 inducer 1 2839627
Direct Blue
ABBV712
Hydrochlorothiazid
WIN 54954
PtdIns
Anticancer agent 253 1983924
GSK
Retavibart
4
Hydroxypheophytin a (羟基叶绿素A)
TNIK&MAP4K4
Acalisib
living
C14 Ceramide (d18 1/14 0)
ZIP(Scrambled) 908012
C6 1
COQ10A Human Pre
Effects of the 5
Actin smooth muscle (SMA) 抗体 (YA5519)（Actin smooth muscle (SMA) Antibody (YA5519)）
Synthesis and pharmacological characterization of novel inverse agonists acting on the viral
Mal
DF 1111301
Pxn Rat Pre
bone lesions
Kadsurenone 95851
6
AURKA
Duloxetine hydrochloride 136434
GNE
FPL
L
IRBM
Mudanpioside E 172705
S013420
Robustaflavone 4′
NSC
8(14)
NLCQ1
Xanthogalol
RGH
CB6513745 380449
Basimglurant sulfate 1034442
Entpd2
CPZEN45
N
Robustaflavone 4′
Chantriolide A 558470
UNC10112785 748142
NSC709257
U
The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)
RGH1962
SAR and identification of 2
Plantagiolide B 913263
EDP
Nimbolinin C 269741
2
CAMKIIα
cDNA cloning and expression of stress
C
Discovery of Small
CPZEN 45
EP013420
The Pharmacokinetics of CPZEN
Antimicrobial compounds from Coleonema album (Rutaceae) PMID 16989307
(±)
RGH
Effective sample preparation procedure for the analysis of free neutral steroids, free steroid acids and sterol sulfates in different tissues by GC
trans
Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1
EDP420
GSK 124576A
EDP
Rifamdin 89499
Raw and Sous
Phytochemical Analysis on Quantification and the Inhibitory Effects on Inflammatory Responses from the Fruit of Xanthii fructus PMID 27013799
1,4
CDK
U
RO4917523
U97456
GSK 124576A 1443139
NSC 709257
SPC
Rifamdin
S
NLCQ
RGH 1962
NLCQ
EDP 420
CPZEN
Glucosyl stigmasterol 2098402
Rhein Mitigates Lung Injury in Severe Acute Pancreatitis Through the Inhibition of MARK4
Normal dermal mesenchymal stem cells improve the functions of psoriatic keratinocytes by inducing autophagy PMID 39864345
Interpretation of the anti
KDM5
Antagonism of proNGF or its receptor p75NTR reverses remodelling and improves bladder function in a mouse model of diabetic voiding dysfunction PMID 32699962
A surprising switch in absolute configuration of anti
HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T
AUR200
Uncovering the key pharmacodynamic material basis and possible molecular mechanism of Xiaoke formulation improve insulin resistant through a comprehensive investigation PMID 38216099
Inhibition by atrial and brain natriuretic peptides of endothelin
In Vitro and In Vivo Characterization of the Alkaloid Nuciferine PMID 26963248
Glucose intolerance caused by a defect in the entero
NS383 309711
MAX deficiency impairs human endometrial decidualization through down
aromatic compounds
4
4,4',4'',4''',4'''',4'''''
Baricitinib
Kobe2602 454453
Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti
BO
WCK
Thalidomide
U
MMP
Anti
Me
Combining Network Pharmacology, Molecular Docking and Experimental Validation to Explore the Effects and Mechanisms of Indirubin on Acute Lymphoblastic Leukemia PMID 39991083
mGluR5
Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2
Uptake of long
NS2B/NS3
Indirubin, a purple 3,2
Research on different compound combinations of Realgar
ATP Synthase
Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF
Fatty acid
Indirubin alleviates bleomycin
L662,025
Memoquin
CFTR corrector 2 1628416
Gardiquimod diTFA 1159840
ERK2 Substrate 947688
Juncuenin D 1161681
PLLA10000
transient linker
Volvaltrate B
2,6
Cy
bivalent antibody
Palomid529
melon flies
SCH25298
(((9H
hDDAH
Claviceps nigricans and Claviceps grohii their alkaloids and phylogenetic placement PMID 18461998
Activation of apoptotic protein in U937 cells by a component of turmeric oil PMID 19250610
(Ferrocenylmethyl)dodecyldimethylammonium bromide (Dodecyl(ferrocenylmethyl)dimethylammonium bromide)
Ebola virus Glycoprotein/GP1 蛋白 (468a.a, Q7T9D9, HEK293, His)
Quorum sensing
Luteolin 3',4'
Boc
7,8
Preserving mitochondrial homeostasis protects against drug
Erythromycin
DCC 抗体 (YA6538)（DCC Antibody (YA6538)）
RK
H1299 dA3
Adamts10
Omphalocarpin
MCE
Downregulation of HSPA12A protects heart against sepsis through suppressing mTOR
CAMK4/CAMKIV
DNA threading bis(9
NVP CXCR2 20
Ppm1g Mouse Pre
Z
Antimycobacterial drugs currently in Phase II clinical trials and preclinical phase for tuberculosis treatment PMID 22991970
Targeting non
Benzyl butyl phthalate (BBP) induces lung injury and fibrosis through neutrophil extracellular traps PMID 35835272
FK
Boc
Nuclear factor E2
LncRNA GASAL1 promotes hepatocellular carcinoma progression by up
MCE
XAT
cGAS
ANAT inhibitor
Mebolazine
Antitubercular agent
NFKB 抑制因子样 1（NFKBIL1）基因
ubiquitin
Generation of Human Trophoblast Stem Cell
IDN5109
BTLA/CD272 蛋白, Rhesus Macaque (HEK293, Fc)
PepPat, a pattern
MU262 1846587
Bt549
DALRD3
Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour
HJ 03
A HD
Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring PMID 34974412
Phenolic diterpenoid derivatives as anti
ASPA 抗体 (YA6466)（ASPA Antibody (YA6466)）
Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin PMID 33814009
Tetrandraxanthones A
WAY 299765
PROTAC EZH2 degrader
Nkg7 Rat Pre
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