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FVIII peptides presented on HLA
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission PMID 39388091
Fluorogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta
Artemisinic acid is a regulator of adipocyte differentiation and C/EBP δ expression PMID 22396222
RO314724
(E),(E)
Rilmenidine suppresses proliferation and promotes apoptosis via the mitochondrial pathway in human leukemic K562 cells PMID 26598394
CK2/PIM1
MCE
NHS
MCE
A new method for the direct tracking of in vivo lignin nanocapsules in Eragrostis tef (Poaceae) tissues PMID 32214284
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease PMID 22194796
IAXO
Ablation of PM20D1 reveals N
Discovery of CC
N
Cyclooxygenase
Erianin inhibits human cervical cancer cell through regulation of tumor protein p53 via the extracellular signal
Ro 8
5(6)
LPAR1 antagonist 1 3032275
ML289 1382481
Biochemical Insights into the Effects of a Small Molecule Drug Candidate on Imatinib
Effects of REV 5901, a 5
Effects of the (Pro)renin Receptor on Cardiac Remodeling and Function in a Rat Alcoholic Cardiomyopathy Model via the PRR
The anti
Structure
In vitro preclinical cardiac assessment of tolterodine and terodiline multiple factors predict the clinical experience PMID 17110801
Pan‑cancer analysis on the role of KMT2C expression in tumor progression and immunotherapy PMID 39091583
Gnetuhainin I 308105
Toralizumab 252662
Synthesis and biological evaluation of 3
Klk7
2
Epha2
Glucagon
Overcoming cisplatin resistance by targeting the MTDH
Encenicline hydrochloride 550999
NLRP3 inflammasome activation mediates estrogen deficiency
Phase Ib Study of Utomilumab (PF
ML 297 (VU 0456810)
Dulozafone (F1933)
Exicorilant (CORT 125281)
Dodecyl Stearate (Stearic Acid Lauryl Ester)
Clickable NAD analogues for labeling substrate proteins of poly(ADP
7
SAA1 Induces TGF
Sesquiterpenes from Curcuma comosa PMID 18663560
Coumarin153 (Coumarin 540A)
Comparative study of superoxide dismutase, catalase and glutathione peroxidase levels in erythrocytes of different animals PMID 901548
Isoguanine and 5
Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection PMID 14638398
Toll
Vincamine prevents lipopolysaccharide induced inflammation and oxidative stress via thioredoxin reductase activation in human corneal epithelial cells PMID 30093956
NEDD4 结合蛋白 2（N4BP2）基因
Tubulin inhibitor 48 63589
Pirmagrel 85691
COQ7
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes PMID 15242786
Multi
Adenosylcobalamin enzymes theory and experiment begin to converge PMID 22516318
Antifungal activity of geraniol and citronellol, two monoterpenes alcohols, against Trichophyton rubrum involves inhibition of ergosterol biosynthesis PMID 25414073
Optimized production and isolation of antibacterial agent from marine Aspergillus flavipes against Vibrio harveyi PMID 29134160
Cardiovascular effects of (R)
The L
IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases PMID 36791209
Antimicrobial activity of quinoxaline 1,4
An antibody
3'
Sex differences in the aging pattern of renin
Raloxifene inhibits tumor growth and lymph node metastasis in a xenograft model of metastatic mammary cancer PMID 20958960
m
Resveratrol
Chromone
Astacidin 1
IL
Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors PMID 27658368
1
Molecular recognition and self
Discovery of a novel dual
HA/Hemagglutinin 蛋白, H1N1 (ACR15621, HEK293, His)
Tedizolid phosphate 856867
Dechlorogeodin and its new dihydro derivatives, fungal metabolites with herbicidal activity PMID 8968402
Discovery of Potent, Orally Bioavailable Sphingosine
MCE
MSRB3 抗体 (YA3252)（MSRB3 Antibody (YA3252)）
CB
CCR1 antagonist 9 1220026
Therapeutic potential of human elafin PMID 21936832
Concepts and principles of glycobiology PMID 8224606
Rad23B 抗体 (YA5286)（Rad23B Antibody (YA5286)）
ROCK
Echs1 Rat Pre
Human pre
Pseudo
KAT3B
HA/Hemagglutinin 蛋白, H1N1 (AAA67183, HEK293, His)
PNLIPRP1 Human Pre
Monolauryl phosphate (Dodecyl dihydrogen phosphate)
Synthesis and structure
Inhibition of USP1 ameliorates hypertensive nephropathy through regulating oxidative stress and ferroptosis a precise treatment via SJB3
hsa
Design and characterization of non
RTKN Human Pre
Potentiating CD8+ T cell antitumor activity by inhibiting PCSK9 to promote LDLR
A sigma
Sophoridine induces apoptosis and S phase arrest via ROS
PCSK9 蛋白, Human (HEK293, mFc)
Clec7a
A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials PMID 27002181
Imaging Hypoxic Stress and the Treatment of Amyotrophic Lateral Sclerosis with Dimethyloxalylglycine in a Mice Model PMID 31344397
WDR5 抗体 (YA4123)(PBS only)（WDR5 Antibody (YA4123)(PBS only)）
Deoxystreptamine kanosaminide 20744
MYO6 Human Pre
Study of the specificity of thrombin with tripeptidyl
Discovery of 3
Caspase
CRBN ligand
Assessing the effects of Thiram to oxidative stress responses in a freshwater bioindicator cladoceran (Daphnia magna) PMID 33160653
Synergistic chemo
Labdane
Mesenchymal
CD131 蛋白, Human (HEK293, His)
MCE
Fmoc
Pyrrolomycin D 81910
Alzheimer's Aβ interacts with cellular prion protein inducing neuronal membrane damage and synaptotoxicity PMID 25599875
Antimalarial agent 56
WALP23
N
Seclidemstat (Standard)
2
Irreversible antagonism of 5HT2c receptors by N
PI3K
Tbx21 Mouse Pre
Valategrast 220847
Polyoxyethylene(9)nonylphenyl ether,branched 68412
AMG
CL2A acid 1846605
Tuning the open
GYKI 52466, a 2,3
Fenimide 60
Differences in nevirapine biotransformation as a factor for its sex
1
Discovery of an Aldo
Synthesis and in vitro cytotoxicity evaluation of 4
Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia PMID 26175414
Function and Phylogeny of Bacterial Butyryl Coenzyme A Acetate Transferases and Their Diversity in the Proximal Colon of Swine PMID 27613689
LGD
RNA molecules that specifically and stoichiometrically bind aminoglycoside antibiotics with high affinities PMID 8823168
Hexachloroparaxylene 68
CP
Selective and specific inhibition of the plasmodium falciparum lysyl
Molecular Design of SERTlight A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain PMID 38557024
Raloxifene
Antiprotealide is a natural product PMID 19133779
Enantioselective UFLC Determination of Hydroxyzine Enantiomers and Application to a Pharmacokinetic Study in Rabbits PMID 27621133
A novel STAT3 inhibitor HO
Z
Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K
Outcomes Associated with 5
FM
DLin
Allantoin, (
Z
DHRS11
Synthesis and antitumor activities of quaternary carbon
New insights into the chemical behavior of S
spasmolytic agent
MCE
From Hit to Lead Discovery of First
Inhibition of potassium
Carphedon
Multitarget AD inhibitor
EME1
Triazinyl
Risdiplam 1825352
GAN diet
Fmoc
Fmoc
Treatment of alkali
Lipophilic modifications to dinucleoside polyphosphates and nucleotides that confer antagonist properties at the platelet P2Y12 receptor PMID 18232657
From Ancient Medicine to Targeted Nanocarrier A Sparganii Rhizoma
Estimation of amitriptyline and its metabolites in serum and urine by GLC using nitrogen
Epha2
C
HSR903
IFNB1 mRNA
IL
SR
MG16 2349329
3,5
ZINC09875266 925200
Design, synthesis, and biological evaluation of novel CDK4/6 and BRD4 dual inhibitors for treatment of KRAS
Aryl hydantoin Ro 13
Modulation of receptor mediated leukotriene release in the perfused heart PMID 3019823
H
Revisiting the SAR of the Antischistosomal Aryl Hydantoin (Ro 13
USP28
MCE
Adenosine A3 receptor activated in H2O2 oxidative stress of primary open
Boc
FF
Derailed protein turnover in the aging mammalian brain PMID 38182797
MLS
Clobetasol 17
Oxymatrine attenuates sepsis
Triisopropyl phosphate 513
H
An Antiviral Effect of Linoleic Acid Against Rhinovirus Infection PMID 40601883
Boc
Elubrixin hydrochloride 688763
Oleoyl
Z
褪黑激素受体 1B（Mtnr1b）基因
Dorzagliatin 1191995
Type III polyketide synthase beta
Z
Pharmacokinetics of LB80331 and LB80317 following oral administration of LB80380, a new antiviral agent for chronic hepatitis B (CHB), in healthy adult subjects, CHB patients, and mice PMID 19223649
Gestational trophoblastic disease PMID 20673583
Design, Synthesis, and Anticancer Evaluation of Novel Tetracaine Hydrazide
Ald
Design, synthesis and evaluation of XZH
Fluorometric assay for adenosine 3',5'
Transient Receptor Potential Ankyrin 1 Contributes to Lysophosphatidylcholine
Branched
Capreomycin IA
Pharmacokinetic and mass balance characterization of [14C] RAY1216, a SARS
UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway PMID 29115622
Phosphorylation of GCN2 by mTOR confers adaptation to conditions of hyper
Tyrosine kinase inhibitor conjugated quantum dots for non
Omocianine (Omocyanine)
The Effect of Oxygen on Bile Resistance in Listeria monocytogenes PMID 27274623
Discovery of Galactopyranose
Binding of botulinum and tetanus neurotoxins to ganglioside GT1b and derivatives thereof PMID 1861141
颗粒酶 A（GZMA）基因
The inhibition of monocarboxylate transporter 2 (MCT2) by AR
Olinone 1770789
A double agent in cancer stopping macrophages wounds tumors PMID 20689551
Structure elucidation
PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity PMID 36350496
SCH
MCE
MSL1 Promotes Liver Regeneration by Driving Phase Separation of STAT3 and Histone H4 and Enhancing Their Acetylation PMID 37279389
Microalgae as sources of high added
Ampkinone 1233082
Troxacitabine
miR
Umizortamig 2599198
Protective effects of esculentic acid against endotoxic shock in Kunming mice PMID 25242384
Targeting ferroptosis A novel therapeutic strategy for the treatment of mitochondrial disease
Occurrence of azo food dyes and their effects on cellular inflammatory responses PMID 29290353
Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities PMID 24092806
(±)
MiR
Inositol 1,3,4,5
Mapping the GRIF
MU262
Antibiotic adjuvant 4 2493985
GuaB
Esculeogenin A 854381
Spinosad blocks CHRNA5 mediated EGFR signaling pathway activation to inhibit lung adenocarcinoma proliferation PMID 39002438
LPE
Synthesis and biological evaluation of 2'
Ac2
WAY
Cdh8 Rat Pre
Acid phosphatase, wheat 9001
Stereochemistry
Ortataxel 186348
Exocytosis proteins and perturbations PMID 8725405
Hyperlipidemia induced by high cholesterol diet inhibits heat shock response in rat hearts PMID 11820796
The Neuroprotective Effect of the HDAC2/3 Inhibitor MI192 on the Penumbra After Photothrombotic Stroke in the Mouse Brain PMID 31512115
NSC
COQ5 Human Pre
Lexibulin dihydrochloride 917111
TLQP
A new type of DNA minor
Coq2 Rat Pre
Racanisodamine 17659
UNC
Structure
MAO
MLS 0322825
Macrophage Dectin
LPE 1
Preclinical Development of an anti
L644711
MUS81
LSD1
Cys
Werner syndrome RecQ helicase
IGF1
Novel Synthesis and Pharmacological Characterization of NOP Receptor Agonist 8
Dopamine D3 receptors regulate GABAA receptor function through a phospho
Thalidomide
Detecting transcription factors with allosteric DNA
The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome PMID 33258073
Huannao Yicong decoction ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by interfering with neurotoxic interaction of Aβ
Luvangetin 483
自噬相关 10（ATG10）基因
Development of Polar Adenosine A2A Receptor Agonists for Inflammatory Bowel Disease Synergism with A2B Antagonists PMID 24900277
PEG tosylate (MW 2000) 58320
Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long
Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP) PMID 19372104
The functional specificity of ERECTA
MAK683
Design, synthesis and biological evaluation of novel alkyl diamine linked bivalent β
Biotin
Treatment of mild non
Negatively
Mequindox Induced Genotoxicity and Carcinogenicity in Mice PMID 29692735
Toxicological evaluation of 3'
IKK
An allosteric cyclin E
Identification of the anti
A peptide inhibitor derived from the conserved ectodomain region of DENV membrane (M) protein with activity against dengue virus infection PMID 25891143
Structure
Structure
Dendrobine modulates autophagy to alleviate ox
Twisted gastrulation signaling modulator 1 promotes the ability of glioma cell through activating Akt pathway PMID 33534374
Nonasaccharide Glc4Xyl3Gal2 129865
Phase I randomized double
Gonadotropin
Safety and Immune Effects of Blocking CD40 Ligand in Multiple Sclerosis PMID 34654708
Design, synthesis, and pharmacology of a highly subtype
SP
METTL3's role in cervical cancer development through m6A modification PMID 38809685
C.I. Acid black 94 6358
Identification, synthesis and characterization of process related desfluoro impurity of ezetimibe and HPLC method validations PMID 29403950
Benzopyrimido
CSF1R signaling blockade stanches tumor
KRAS is vulnerable to reversible switch
Identification of Indoquinazoline Derivatives as Novel NR4A1 Agonists by Suppressing Adipocyte Lipogenesis for Treatment of Obesity PMID 40815010
Maniladiol
AA 344
Targeting the PI3K/AKT/mTOR Signaling Pathway in the Treatment of Human Diseases Current Status, Trends, and Solutions PMID 36503229
8
Caprylic Acid (FFA C8 0) promotes the progression of prostate cancer by up
Design and Synthesis of 2
Modulation of Oxidative Phosphorylation with IM156 Attenuates Mitochondrial Metabolic Reprogramming and Inhibits Pulmonary Fibrosis PMID 34593558
PAI
Cytotoxic constituents of Isodon rubescens var. lushiensis PMID 14575445
New lipophilic isoniazid derivatives and their 1,3,4
Protective effects of bellidifolin in hypoxia
Miransertib hydrochloride 1313883
Identification of Small
A tale of two proteins PACT and PKR and their roles in inflammation PMID 33387379
Novel macrocyclic antibiotics megovalicins A, B, C, D, G and H. I. Screening of antibiotics
Epigenetics meets GPCR inhibition of histone H3 methyltransferase (G9a) and histamine H3 receptor for Prader
Methoxyacetic acid 625
Discovery, synthesis, and optimization of antimalarial 4(1H)
A first
Inhibition of HIV
Lipid C2 3003022
Geranylgeraniol and Neurological Impairment Involvement of Apoptosis and Mitochondrial Morphology PMID 26978350
Development of a simple and rapid method for producing non
The lncRNA KIF9
Phortress (Standard)
Mitochondrial dynamic modulators attenuate iron overload
Homoharringtonine suppresses imatinib resistance via the Bcl
A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency PMID 23386436
Tagetes oil
Antibody
Cbz
Osteocyte
Benzothiazepine CGP37157 and its 2'
Biosynthesis and Cellular Functions of Tartaric Acid in Grapevines PMID 33747023
Zizyflavoside B
Serine hydroxymethyltransferase 2 expression promotes tumorigenesis in rhabdomyosarcoma with 12q13
Stereoselective interaction of procyclidine, hexahydro
Development of the first ultra
Lung
1,2
TAK
Cutting edge inflammatory responses can be triggered by TREM
MCE
YY1 转录因子（YY1）基因
5
Cyclen
Differential apoptosis
Ala
Flexible scaffold
MCE
CGP 52432 a novel potent and selective GABAB autoreceptor antagonist in rat cerebral cortex PMID 8103461
OXCT1 regulates hippocampal neurogenesis and alleviates cognitive impairment via the Akt/GSK
Cardiogenol C hydrochloride 1049741
Clavamycin F 103059
A Comparative Study on Visual Detection of Mycobacterium tuberculosis by Closed Tube Loop
Structure
Interaction of arylpiperazines with 5
Tanogitran 637328
Plant Thaumatin
NEP108 3031840
Naringin alleviates H2O2
Pociredir 2490676
MCE
P
Molecular design, synthesis and anticancer activity of new thiopyrano[2,3
Discovery of Broad
Aconine inhibits RANKL
The Advantages of Targeted Protein Degradation Over Inhibition An RTK Case Study PMID 29129716
Screening and biological evaluation of a novel STAT3 signaling pathway inhibitor against cancer PMID 27727126
Roles of Proteins Containing Immunoglobulin
In vitro and in vivo antibacterial activities of T
地西泮结合抑制因子，酰基辅酶 A 结合蛋白（DBI）基因
Bucloxic acid 32808
Oxidative stress and DNA damage induced by trifloxystrobin on earthworms (Eisenia fetida) in two soils PMID 34293608
Guizhi Fuling Wan reduces autophagy of granulosa cell in rats with polycystic ovary syndrome via restoring the PI3K/AKT/mTOR signaling pathway PMID 33460753
Tolerance in the replacement of the benzhydrylic O atom in 4
FGFR2
Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α PMID 40411250
Mucoid Pseudomonas aeruginosa, TNF
Tolimidone 41964
Sakurasosaponin inhibits lung cancer cell proliferation by inducing autophagy via AMPK activation PMID 37920436
Mixture toxicity of the antiviral drug Tamiflu((R)) (oseltamivir ethylester) and its active metabolite oseltamivir acid PMID 19939473
Development of a Selective and Potent PRMT4 PROTAC Degrader with Efficacy against Multiple Myeloma in Vitro and in Vivo PMID 40531929
Melanin PMID 32097632
Formononetin attenuates myocardial ischemia/reperfusion injury by regulating neutrophil extracellular traps formation and platelet activation via platelet CD36 PMID 40250000
Excess fibronectin 1 participates in pathogenesis of pre
Randomised, double
Lansiumamide B and SB
Lipstatin 96829
Silencing CXCR6 promotes epithelial
EZH2
Properties and Applications of Polyvinyl Alcohol, Halloysite Nanotubes and Their Nanocomposites PMID 26703542
PD 165929 185215
150D4 2866306
SKI
Electroacupuncture Attenuates Morphine Tolerance in Rats with Bone Cancer Pain by Inhibiting PI3K/Akt/JNK1/2 Signaling Pathway in the Spinal Dorsal Horn PMID 33660537
Isogenic Sets of hiPSC
Synthetic inhibitors of bacterial cell division targeting the GTP
Phosphoproteome and drug
MCE
Group I mGluR antagonist rescues the deficit of D1
The ceiling effect of pharmacological postconditioning with the phytoestrogen genistein is reversed by the GSK3beta inhibitor SB 216763 [3
(1S)
Picroside II 39012
Identification of pheophorbide a and its related compounds as possible anti
DA
MCE
Human neural stem cell
Fmoc
Synthesis of a 2
Neuromedin S(rat) TFA
Fumarate Hydratase, Human
ICMT
Theranostic cRGD
GR 55562 159533
Antibody Response against Cowpea Mosaic Viral Nanoparticles Improves In Situ Vaccine Efficacy in Ovarian Cancer PMID 32133838
Linaprazan glurate 1228559
Architecture of P2Y nucleotide receptors structural comparison based on sequence analysis, mutagenesis, and homology modeling PMID 15481977
MCE
Pharmacokinetics of marbofloxacin in horses PMID 12117108
Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine
SCF/c
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells PMID 32820120
gamma Sarcoglycan 抗体 (YA6852)（gamma Sarcoglycan Antibody (YA6852)）
On the mechanism of the inhibitory action of the spirolactone SC 9376 (aldadiene) on the production of corticosteroids in rat adrenals in vitro PMID 4267313
Efficacy of Integrase Strand Transfer Inhibitors and the Capsid Inhibitor Lenacapavir against HIV
NEK2 promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through the Wnt/β
Maculatin 1.1 disrupts Staphylococcus aureus lipid membranes via a pore mechanism PMID 23689707
Purified neonatal plasmacytoid dendritic cells overcome intrinsic maturation defect with TLR agonist stimulation PMID 16690948
Cannabis
Characterization of the biosynthesis gene cluster for the pyrrole polyether antibiotic calcimycin (A23187) in Streptomyces chartreusis NRRL 3882 PMID 21173184
Triterpene tetraglycosides from the sea cucumber Stichopus horrens PMID 28934865
Scpep1
Transferrin R2 蛋白, Mouse (HEK293, mFc)
20
EDAR 蛋白, Cynomolgus (HEK293, Fc)
KuINins as a New Class of HIV
Synthesis and anti
Pyrvinium
L
Calorimetric studies of the role of magnesium ions in yeast enolase catalysis PMID 4598292
Amylin (8
Establishing artificial gene connections through RNA displacement
Ageladine A, a pyrrole
Comparative Effectiveness of Different Interventions of Perivascular Hyaluronidase PMID 32221213
Gynostemma Extract 80321
Papaverine
KCNJ6 Human Pre
Tanshinoic acid A
JQ
Lactoferrin ameliorates carfilzomib
Design and synthesis of gambogic acid analogs as potent cytotoxic and anti
A Bone
3′
Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus
CRBN ligand
Increased activity of the orexin system in the paraventricular nucleus contributes to salt
Phospholipase D2 Regulates Microtubule Acetylation by Modulating Gsk3β
CD73
CXC 基序趋化因子配体 13（CXCL13）基因
Enoticumab 1192578
DBCO
MCE
Short
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