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Kochia scoparia seed extract suppresses VEGF
(E/Z)
Latrunculin B modulates electrophysiological characteristics and arrhythmogenesis in pulmonary vein cardiomyocytes PMID 26839418
cGAS
6
All
Preclinical disposition of MGS0274 besylate, a prodrug of a potent group II metabotropic glutamate receptor agonist MGS0008 for the treatment of schizophrenia PMID 31523433
MCE
Evaluation of cimaterol for finishing swine including a drug withdrawal period PMID 2564387
IL
Alfy, a novel FYVE
CRISP
Recent strategies targeting Embryonic Ectoderm Development (EED) for cancer therapy Allosteric inhibitors, PPI inhibitors, and PROTACs PMID 35093670
An examination of age
Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors PMID 23278456
Synthesis and biological evaluation of nusbiarylin derivatives as bacterial rRNA synthesis inhibitor with potent antimicrobial activity against MRSA and VRSA PMID 35580381
Identification of pleckstrin
肌球蛋白 IIIB（MYO3B）基因
Macrophage migration inhibitory factor interactions with glutathione and S
The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1
Synthesis of rebaudioside
The melatonin metabolite N
A small molecule inhibitor of ARF GTPase protein 1 limits liver and colon cancer cell growth and metastasis PMID 41720764
Tuvirumab 138660
Pharmacological properties of the marine natural product marinopyrrole A against methicillin
Colchicine acts selectively in the liver to induce hepatokines that inhibit myeloid cell activation PMID 33846641
A new furofuran lignan from Isodon japonicus PMID 19407966
Xanthine Alkaloids Occurrence, Biosynthesis, and Function in Plants PMID 28194561
The protective effect of tinoridine against carbon tetrachloride hepatotoxicity PMID 6892737
Optimized Synthesis and Antioxidant Activity of Anthocyanins Delphinidin
PTGFRN
Z
Boc
Boc
Dexamethasone acetate 1177
D
Bifonazole (Bay H
L644711
MOC
3,5
Boc
Boc
Boc
Fmoc
Identification of Novel 5,6
Isocucurbitacin B inhibits gliomas through the promotion of anoikis by targeting caveolin 1 PMID 40516904
(R)
RND1 inhibits epithelial
Discovery of PKM2 activators from Aconiti Lateralis Radix Praeparata via computer
EPH 受体 A2（EPHA2）基因
Benzaldehyde
Inhibiting endoplasmic reticulum stress by activation of G
H
Z
Design, synthesis and biological evaluation of sulfur
Mitochondrial superoxide production, biological effects, and activation of uncoupling proteins PMID 15304252
Stimulation of haematopoiesis in primates by continuous infusion of recombinant human GM
IL
Boc
Methocinnamox 117339
Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF
Discovery and Optimization of N
Etidocaine 36637
MCE
Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration PMID 29054982
Methoxy
Long
Immunocytochemical evidence for PDBu
TLQP
Micro
Creatine
Wnt5a Mouse Pre
Rifamycin W Analogues from Amycolatopsis mediterranei S699 Δ rif
PHD
Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA PMID 38820338
泛素 A
Endothelium
C1r
Hspa1a
Combination of Cbl
Design, synthesis and biological evaluation of novel 31
Identification of novel series of pyrazole and indole
MCF 579474
Efficient new constructs against triple negative breast cancer cells synthesis and preliminary biological study of ferrocifen
CDKN2A/B homozygous deletion sensitizes IDH
Absorption and metabolism of anitrazafen, a topically effective anti
NMI 8739 (Standard)
Exatecan
Inhibitory effect of 2,4
The structure of 2
Antibiotic adjuvant 4
Ability of innate defence regulator peptides IDR
Shrimp MANF maintains hemocyte viability via interaction with a tyrosine kinase Abl PMID 36863646
Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking PMID 27729839
Exploring the Immunotherapeutic Potential of Oleocanthal against Murine Cutaneous Leishmaniasis PMID 35803258
Cepharanthine potently enhances the sensitivity of anticancer agents in K562 cells PMID 15958061
Monitoring ATPase induced pH changes in single proteoliposomes with the lipid
follicular development
DDB1 regulates the activation
On the beta
Mmrn1 Mouse Pre
Baicalin ameliorates neuroinflammation by targeting TLR4/MD2 complex on microglia via PI3K/AKT/NF
Iristectorin B 94396
Sec17
Androstenediol 3
Preclinical studies with pyrazolopyridine non
Mast cell
Phe
DDR1 蛋白, Rat (HEK293, hFc)
Klf6 Mouse Pre
Rolditamig 3038136
IL1A a novel prognostic biomarker and potential therapeutic target for renal clear cell carcinoma PMID 40612864
Proliferative behaviours of CD90
Z
sequence
CBP/p300
Lipsome
MCE
SNARE
H
UMP functions as an endogenous regulator of NR4A1 to control gastric cancer progression PMID 41270758
AMPK agonist AICAR ameliorates maternal hepatic lipid metabolism disorder, inflammation, and fibrosis caused by PM2.5 exposure during pregnancy PMID 40082541
Fenimide
ProX1
7
Roseoside 54835
1
Cys
3
Sanfetrinem cilexetil (GV 118819X)
Clinical Experience With IV Angiotensin II Administration A Systematic Review of Safety PMID 28489648
SETDB1 targeting SESN2 regulates mitochondrial damage and oxidative stress in renal ischemia
Traxanox 58712
MCE
FASD folic acid and formic acid
Croton linearis
Disposition and Pharmacokinetics of a GalNAc3
(S)
Serrumab a human monoclonal antibody that counters the biochemical and immunological effects of Tityus serrulatus venom PMID 22424317
Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV
QRA
MG16
Focal adhesion kinase inhibition induces membrane accumulation of aquaporin
Fragrance material review on hexyl salicylate PMID 18022307
H
Sixty
plantain
Structure
CRBN ligand
Studies on WF
cell monolayers
Fmoc
BMS
Glucosyltransferase the gene arrangement and enzyme function PMID 15647808
RXFP2
TLR9
XPD 抗体 (YA2434)（XPD Antibody (YA2434)）
脑啡肽原（PENK）基因
Calpain
Z
Myc overexpression enhances apoptosis induced by small molecules PMID 17012843
Amitriptyline
A prominent air pollutant, Indeno[1,2,3
1,2
Probing the pharmacophore of ginkgolides as glycine receptor antagonists PMID 17352465
Targeted Delivery of Auristatin
Mebolazine (Dimethazine)
Pyroptosis Remodeling Tumor Microenvironment to Enhance Pancreatic Cancer Immunotherapy Driven by Membrane Anchoring Photosensitizer PMID 35981886
WAY
白介素 10 受体亚基 β（IL10RB）基因
3,5,6,7,8,3',4'
PD
Z8779877149 (Z7149)
Influence of ester and ether linkage in phospholipids on the environment and dynamics of the membrane interface a wavelength
Biological activity of 1,2,3
Anti
Synthetic FXR agonist GW4064 prevents diet
Triacylglycerol and phytyl ester synthesis in Synechocystis sp. PCC6803 PMID 32123083
The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα PMID 22503743
Development of Second
Immunoenhancing activity of protopanaxatriol
Changes in 4
Mmrn1
BTK
Vgf
NECTIN4
Elafin Reverses Pulmonary Hypertension via Caveolin
Expression of Pork Plectin during Postmortem Aging PMID 31518118
Phagocytosis in Dictyostelium discoideum is inhibited by antibodies directed primarily against common carbohydrate epitopes of a major cell
Differential ability of surface and endosomal TLRs to induce CD8 T cell responses in vivo PMID 24688022
MCE
Transcriptional control of melanoma metastasis the importance of the tumor microenvironment PMID 21147226
Accelerated polymer
Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis PMID 26161952
The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor
Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment
Antitumor agents. 21. A proposed mechanism for inhibition of cancer growth by tenulin and helenalin and related cyclopentenones PMID 845864
IDH1/MDH1 deacetylation activates the cGAS
Serendipitous discovery of Class I HDAC inhibitors from rational design of molecular glue degraders targeting HDAC PMID 37995564
Cirramycin B1 57425
2,6
Mechanism Actions of Coniferyl Alcohol in Improving Cardiac Dysfunction in Renovascular Hypertension Studied by Experimental Verification and Network Pharmacology PMID 39337549
GDC0927
Independent evolution of oleate hydratase clades in Bacillales reflects molecular convergence PMID 39726433
Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii From Screening Impurity to In Vivo Efficacy PMID 39172133
Galactosyl cholesterol 51704
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation PMID 31445234
Role of gonadotropin
A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6
Salicyl alcohol 90
Crepidatin
一氧化氮
Metabolism and toxicity studies supporting the safety of rebaudioside D PMID 23766392
N
CXCL3 Human Pre
Crocein orange G 1934
Zevontabart 3060218
H
Roseoside
T
PI3K/AKT
RPR102341
Menin
MCE
Boeravinone F 137810
TMPRSS2 A potential target for treatment of influenza virus and coronavirus infections PMID 28778717
KLF6 Human Pre
Tracazolate 41094
Fmoc
PXR Activation Relieves Deoxynivalenol
HY
Flupropanate
Design, synthesis, and biological evaluation of (thio)urea derivatives as potent Escherichia coli β
Lutein attenuated methylglyoxal
JWG045
Key Structural Elements for Cellular Uptake of Acinetobactin, a Major Siderophore of Acinetobacter baumannii PMID 28102683
2,4
Downregulation of KCTD12 contributes to melanoma stemness by modulating CD271 PMID 31565480
MCE
Lead optimization of imidazopyrazines a new class of antimalarial with activity on Plasmodium liver stages PMID 25147620
His
Biasing Opioid Receptors and Cholesterol as a Player in Developmental Biology PMID 27662248
PIM2 Promotes the Development of Ovarian Endometriosis by Enhancing Glycolysis and Fibrosis PMID 37059967
MCE
GSK1829820A 1443138
Synthesis and SAR of ⁹⁹mTc/Re
Roblitinib (Standard)
自然杀伤细胞
A novel protein kinase is essential in bloodstream Trypanosoma brucei PMID 27018127
building
10
Crocatin B 143816
The antimicrobial peptide thanatin disrupts the bacterial outer membrane and inactivates the NDM
Fc gamma RIIIA/CD16a 蛋白, Human (Biotinylated, F176V, HEK293, His
Acetyl
The abuse potential of oxethazaine effects of oxethazaine on drug
miR
Wnt antagonists suppress herpes simplex virus type 1 productive infection PMID 33961904
4
Laboratory Evaluation of Natural and Synthetic Aromatic Compounds as Potential Attractants for Male Mediterranean fruit Fly, Ceratitis capitata PMID 31261896
Activation of transient receptor potential vanilloid 4 is involved in pressure overload
AMPK/MFF Activation Role in Mitochondrial Fission and Mitophagy in Dry Eye PMID 36374514
Pharmacological characterization of MK
ISX
MCE
ROS, mitochondria and the regulation of autophagy PMID 17804237
AVN
H
Lotusine G a new cyclopeptide alkaloid from Zizyphus lotus PMID 11864766
mGlu2 and mGlu3 Negative Allosteric Modulators Divergently Enhance Thalamocortical Transmission and Exert Rapid Antidepressant
H
Fmoc
CFTR Inhibitors Display Antiviral Activity against Herpes Simplex Virus PMID 39205282
H
Early recruited neutrophils promote asthmatic inflammation exacerbation by release of neutrophil elastase PMID 32278493
Cyclic AMP sodium 37839
β
FITM2 Human Pre
Ataxin 1 抗体 (YA4739)（Ataxin 1 Antibody (YA4739)）
A Comparative Assessment Study of Known Small
Fmoc
Porcn as a novel therapeutic target in cancer therapy A review PMID 35971741
NAT8L
trans
VGF Human Pre
DSPE
Tesevatinib 781613
Design, synthesis, and biological evaluation of dual
PTC
Inhibition of pirfenidone on TGF
CSF1R inhibition reprograms tumor
具有序列相似性的家族 83 成员 D（FAM83D）基因
Retatrutide 2381089
Inhibitory effect of flavonoids on 26S proteasome activity PMID 19795881
Pharmacokinetics of the antiviral agent beta
MCE
The structural basis for the human procollagen lysine hydroxylation and dual
Formononetin protects against cisplatin‑induced acute kidney injury through activation of the PPARα/Nrf2/HO‑1/NQO1 pathway PMID 33416097
Antimalarial agent 15 956928
Puerarin a novel antagonist to inward rectifier potassium channel (IK1) PMID 21327545
RO6806051 1433901
Pentabromopseudilin a myosin V inhibitor suppresses TGF
TTF2 promotes replisome eviction from stalled forks in mitosis PMID 39651145
Novel Tetrahydropyrido[4,3
Compromised NLRP3 and AIM2 inflammasome function in autoimmune NZB/W F1 mouse macrophages PMID 30052286
LY96 Human Pre
L
Hexyl hexanoate 6378
Studies on the mechanism of action of monoamine oxidase metabolism of N,N
AAZ2 induces mitochondrial
Pterosin B improves cognitive dysfunction by promoting microglia M1/M2 polarization through inhibiting Klf5/Parp14 pathway PMID 39413455
Chemical proteomics identifies Nampt as the target of CB30865, an orphan cytotoxic compound PMID 20609415
Isoxazolyl, oxazolyl, and thiazolylpropionic acid derivatives as potent alpha(4)beta(1) integrin antagonists PMID 11551757
Toosendanin inhibits T
Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor PMID 20372971
Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death PMID 32219156
Development and Characterization of Benzoselenazole Derivatives as Potent and Selective c
Angiotensin
Cornus Officinalis Total Glycosides Alleviate Granulomatous Lobular Mastitis via the B7
A novel ICK mutation causes ciliary disruption and lethal endocrine
Rad50 抗体 (YA4408)（Rad50 Antibody (YA4408)）
Structural and photophysical studies of highly stable lanthanide complexes of tripodal 8
Mianserin
p38
GSK3 alpha 抗体 (YA2971)(PBS only)（GSK3 alpha Antibody (YA2971)(PBS only)）
N2'
Fc gamma RIIB/CD32b 蛋白, Mouse (HEK293, His)
锌指蛋白 143（ZNF143）基因
Noradrenergic and peptidergic sympathetic regulation of cutaneous microcirculation in the rat PMID 9151939
Viltolarsen 2055732
(R,R)
MMP
Validation of N
Design, synthesis, and investigation of anti
SSRP1 Human Pre
BAYV3522
Amino
Synthetic approaches to the microtubule
Regiospecificity and stereospecificity of human UDP
Wu
House dust mite
ERK5 抗体 (YA5416)（ERK5 Antibody (YA5416)）
Noscapine crosses the blood
EPHA2
O
Dual Inhibition of Mycobacterium tuberculosis and the Host TGFBR1 by an Anilinoquinazoline PMID 37871287
MCE
Extracellular Matrix/Glycopeptide Hybrid Hydrogel as an Immunomodulatory Niche for Endogenous Cardiac Repair after Myocardial Infarction PMID 37318159
Identification of critical secondary components of the sex pheromone of the navel orangeworm (Lepidoptera Pyralidae) PMID 20429444
1,4
Ovarian Stimulation in Mice Resulted in Abnormal Placentation through Its Effects on Proliferation and Cytokine Production of Uterine NK Cells PMID 36982985
Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation PMID 12110321
Z
H
Indonesian medicinal plants. XXI. Inhibitors of Na+/H+ exchanger from the bark of Erythrina variegata and the roots of Maclura cochinchinensis PMID 9353889
N1,N12
Antiplatelet agents can promote two
Anticonvulsant effect of fosphenytoin in amygdala
Low molecular weight dextran sulfate binds to human myoblasts and improves their survival after transplantation in mice PMID 23031415
Deethylterbutryne
Fmoc
Fmoc
APOE modulates ferroptosis to drive macrophage polarization toward the M2 type and enhance PTC migration and invasion PMID 40245754
AITRL/TNFSF18 蛋白, Cynomolgus (HEK293, His)
t
Fmoc
MCE
Fmoc
Fmoc
H
Rational Design of Novel Quinazolinone
Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer PMID 38370808
L
FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE
PPM1D Human Pre
5(6)
Fcar Rat Pre
B7
Osteopontin derived from hypoxia
Metabolomic identification of the target of the filopodia protrusion inhibitor glucopiericidin A PMID 20851348
(2S,4S)
蛋白磷酸酶，Mg2+/Mn2+ 依赖性 1G（PPM1G）基因
CEA 细胞粘附分子 4（CEACAM4）基因
Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10
Short PEG
IQZ23 2415643
The AhR agonist VAF347 augments retinoic acid
Discovery of AZD2716 A Novel Secreted Phospholipase A2 (sPLA2) Inhibitor for the Treatment of Coronary Artery Disease PMID 27774123
SB 9200, a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants PMID 28303593
Effect of lipophilicity at N
Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site
Tumour necrosis factor
SOX10 抗体 (YA4110)（SOX10 Antibody (YA4110)）
Δ9
Limaprost PMID 17209669
吡咯啉
Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal Plasticity PMID 32326204
Cholesteryl docosahexaenoate (Cholesteryl cervonate)
O
Effects of beta
(S)
A regio
Exploration of 1,3
D
Ganoderenic acid K 942950
Lithospermic acid improves diabetic kidney fibrosis by regulating Piezo1/TGF
CEACAM4 Human Pre
Sedoheptulose 1,7
Fmoc
Therapeutic inhibition of PPARα
肌球蛋白轻链激酶家族成员 4（MYLK4）基因
Phenolic constituents from the root bark of Morus alba L. and their cardioprotective activity in vitro PMID 27974159
MCE
SYY
RGH 1875
Antidepressants attenuate the dexamethasone
AKT serine/threonine kinase 2
SKIL Human Pre
mycoplanecins
Nicotinamide N
Stability analysis of glutamic acid linked peptides coupled to NOTA through different chemical linkages PMID 24533430
Amino
β
Design, Synthesis, and Structure
Benzyl
Cxcl3 Rat Pre
GP130 modulator
Tifa Rat Pre
MCE
Tinoridine 24237
FGR 抗体 (YA3732)（FGR Antibody (YA3732)）
Advances in research on pharmacotherapy of sarcopenia PMID 34553120
lung protection
Identification of compound CA
TRIM29 抗体 (YA2552)（TRIM29 Antibody (YA2552)）
LncRNA GAS5 inhibits miR
Viral tegument proteins restrict cGAS
Design, synthesis and SAR study of 2
BOB1 抗体 (YA5521)（BOB1 Antibody (YA5521)）
含三方基序 14（TRIM14）基因
U 101958
9
Design, Synthesis, and Structure
2
3,5,6,7,8,3',4'
Beneficial effects of the dual L
Acetylexidonin 116368
RE 11775 25474
Ceritinib mesylate (LDK378 mesylate)
FOXO1 and FOXO3a sensitize non
miR
ORC1 抗体 (YA9189)（ORC1 Antibody (YA9189)）
Ractopamine
Ethyl glycylmethioninate hydrochloride
ERK Signal Suppression and Sensitivity to CH5183284/Debio 1347, a Selective FGFR Inhibitor PMID 26438159
L 44
Cathepsin K
IC
Lignarenone B 125010
BI3802
A radicicol
DCB 6971
Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors PMID 25609199
BUBR1 抗体 (YA2757)(PBS only)（BUBR1 Antibody (YA2757)(PBS only)）
(2'OMe
CRBN ligand
Synthesis, Spectroscopic Characterization, Structural Analysis, Antimycobacterial Study, Molecular Docking, DFT, and ADME Studies of Novel Hybrid Pyrrole
PF
83899
PFKFB3
Slpi
天冬酰胺酶和异天冬氨酰肽酶 1（ASRGL1）基因
Drug screening with human SMN2 reporter identifies SMN protein stabilizers to correct SMA pathology PMID 30910806
叶酸受体α（FOLR1）基因
Olorofim (Standard)
Hars2
MCE
Ro
G6PD
MCE
CB
MDRTB
Mu
L
Bamaquimast 135779
Design, synthesis and antimicrobial evaluation of novel glycosylated
CV
MtbHU
L0042
Discovery of benzothiazole amides as potent antimycobacterial agents PMID 30172617
P31
Ethyl lithospermate 946389
Protamine
Polysaccharide glucomannan isolated from Heterodermia obscurata attenuates acute and chronic pain in mice PMID 23399258
mTORC1 and mTORC2 Complexes Regulate the Untargeted Metabolomics and Amino Acid Metabolites Profile through Mitochondrial Bioenergetic Functions in Pancreatic Beta Cells PMID 35893876
isoleucine
Structure
Toxicity of the bionematicide 1,4
Insulin Receptor 抗体 (YA3666)(PBS only)（Insulin Receptor Antibody (YA3666)(PBS only)）
DCDC2 抗体 (YA9026)（DCDC2 Antibody (YA9026)）
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