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TGF
BMSpep
Combined AKT and MEK Pathway Blockade in Pre
Honokiol Reduces Fungal Load, Toll
Drug
VIT
WL12
Luxdegalutamide
MDV3100
Sepantronium
Identification of anabolic selective androgen receptor modulators with reduced activities in reproductive tissues and sebaceous glands PMID 19846549
ARV110
Nuclear Medicine Application of Pentixafor/Pentixather Targeting CXCR4 for Imaging and Therapy in Related Disease PMID 36529918
U
UGT2B17 Expedites Progression of Castration
ARV 110
Inhibition of cytochrome P450 with proadifen alters the excitability of brain catecholamine
TLS/FUS 抗体 (YA3197)（TLS/FUS Antibody (YA3197)）
QSER1 preserves the suppressive status of the pro
metastatic
Bavdegalutamide
DOTA conjugate with an albumin
U
radionuclides
Regulation of Small GTPase Rab20 by Ikaros in B
68Ga
biological material
LncRNA NEAT1_1 suppresses tumor
androgen receptor
Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells PMID 40478628
Sepantronium bromide 781661
Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin PMID 26721606
ODM201
Enzalutamide
RNA virus receptor Rig
Stress
Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer PMID 25552366
YM155
Gallium
A combination of YM
Myricanol 5
A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression PMID 35476451
ubiquitination
FOXP1 抗体 (YA1283)（FOXP1 Antibody (YA1283)）
Combination radionuclide therapy using 177Lu
Role of 20
Poloxamer 235 (P85) (PEG
AIMP1 exerts hearing protection role in age related hearing loss mice by regulating SIRT1 expression PMID 40836274
Bavdegalutamide 2222112
Roseoside Is a Bioactive Compound in Kirengeshoma koreana Nakai Extract with Potent In Vitro Antiviral Activity Against Hepatitis C Virus PMID 39519772
PKA/PRKACA 蛋白, Human (Active, sf9, GST)
3D microfluidic chip
SPOP is essential for DNA
MDV 3100
BMSpep 57
Estrogen receptor antagonist 1
YM 155
YM155, a novel small
NOTA
Biodistribution and clearance of small molecule hapten chelates for pretargeted radioimmunotherapy PMID 20533093
Fursultiamine Alleviates Choroidal Neovascularization by Suppressing Inflammation and Metabolic Reprogramming PMID 33107903
Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer PMID 29340039
Nutmeg as a narcotic. A contribution to the chemistry and pharmacology of nutmeg (Myristica fragrans) PMID 4996769
Vitamin B1 Derivative
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization PMID 35334248
Testosterone
Radiosensitizing effect of YM155, a novel small
PCM1 Human Pre
Pak5 Rat Pre
The memristive effect as a novelty in drug monitoring PMID 28675222
Berberine attenuates XRCC1
Tauroursodeoxycholic Acid Attenuates Renal Tubular Injury in a Mouse Model of Type 2 Diabetes PMID 27669287
68Ga
WL
Anti
TP53 loss
Lead optimization and efficacy evaluation of quinazoline
AR
Nootkatone Derivative Nootkatone
ODM 201
Next
Adenosine 5& 039;
Overexpression of IFIT2 inhibits the proliferation of chronic myeloid leukemia cells by regulating the BCR‑ABL/AKT/mTOR pathway PMID 32124954
Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration
HSDB
AR+TREM2+ macrophage induced pathogenic immunosuppression promotes prostate cancer progression PMID 40730555
Aptamer
Restored Thymic Output after Androgen Blockade Participates in Antitumor Immunity PMID 36548468
PRMT5 MEP50 Are Mediators of Treatment
YAP1 regulates prostate cancer stem cell
PSMA 11
PRKACB 蛋白, Human (Active, sf9)
Nphs1 Rat Pre
The reversible inhibitor SR
The assembly of RAB22A/TMEM33/RTN4 initiates a secretory ER
A novel calcium
The role of reelin in the pathological mechanism of depression from clinical to rodents PMID 36103758
Discovery and biological evaluation of novel androgen receptor antagonist for castration
Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer PMID 33388655
Beta
castration
Inhibition of GCN2 sensitizes ASNS
The Master Neural Transcription Factor BRN2 Is an Androgen Receptor
KLF5 Is Crucial for Androgen
A Genome Wide CRISPR Screen Reveals That HOXA9 Promotes Enzalutamide Resistance in Prostate Cancer PMID 39300912
DS28120313 2146177
Targeting valine catabolism to inhibit metabolic reprogramming in prostate cancer PMID 39025852
BAY
Longitudinal single
Discovery of Potent, Specific, and Orally Available NLRP3 Inflammasome Inhibitors Based on Pyridazine Scaffolds for the Treatment of Septic Shock and Peritonitis PMID 39169676
Affinity profiles for human somatostatin receptor subtypes SST1
The androgen receptor mediates antiapoptotic function in myometrial cells PMID 25032861
利妥昔单抗
Design, synthesis, and biological evaluation of pyrido[2,3
Pharmacokinetics of enzalutamide, an anti
Identification and Application of Gene Expression Signatures Associated with Lifespan Extension PMID 31353263
E 2027
PTG 300
Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell
IL8 Expression Is Associated with Prostate Cancer Aggressiveness and Androgen Receptor Loss in Primary and Metastatic Prostate Cancer PMID 31604846
Serotonin Receptor
NR3C3
antifungal activity
A controlled trial of leuprolide with and without flutamide in prostatic carcinoma PMID 2503724
Cotadutide
Autoimmune Diseases Following Environmental Disasters A Narrative Review of the Literature PMID 39273791
STX1A Human Pre
WWP1 upregulation predicts poor prognosis and promotes tumor progression by regulating ubiquitination of NDFIP1 in intrahepatic cholangiocarcinoma PMID 35264565
1
Peramivir A Novel Intravenous Neuraminidase Inhibitor for Treatment of Acute Influenza Infections PMID 27065996
Med1
5
Transcriptional profiling clarifies a program of enzalutamide extreme non
JNK/p38 MAPK
NDUFAF2 Human Pre
Novel tricyclic poly (ADP
dementia with Lewy bodies
Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer PMID 34737261
Selective in vitro and in silico butyrylcholinesterase inhibitory activity of diterpenes and rosmarinic acid isolated from Perovskia atriplicifolia Benth. and Salvia glutinosa L PMID 27817931
Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression PMID 40111564
MH6499c4
AM833 Is a Novel Agonist of Calcitonin Family G Protein
PSMA
Characteristics of flutamide action on prostatic and testicular functions in the rat PMID 2838689
JPC0323
Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones PMID 37267948
Angiotensin II upregulates RANKL/NFATC1 expression in synovial cells from patients with rheumatoid arthritis through the ERK1/2 and JNK pathways PMID 33952303
Discovery of TAK
IL
Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP
Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient
HSPA8 dampens SCAP/INSIG split and SREBP activation by reducing PKR
Charting the growth through intelligence A SWOC analysis on AI
Mucin 1 expression is regulated by hsa_circ_0055054/microRNA‑122‑5p and promotes hepatocellular carcinoma development PMID 38983125
Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2 PMID 34387469
Synthesis and biological evaluation of novel carnosic acid derivatives with anticancer activity PMID 41058673
Nectin
IL
Aging increases susceptibility to liver fibrosis through enhanced NAT10
Design, synthesis and antitumor efficacy evaluation of a series of novel β
Mas
The CXCL8
Discovery of novel HIV
Feline Calicivirus Proteinase
Streptomyces distallicus, a Potential Microbial Biolarvicide PMID 36040208
HIF
Skeletal Muscle
Reversal of abnormal corneal epithelial cell morphologic characteristics and reduced corneal sensitivity in diabetic patients by aldose reductase inhibitor, CT
A high dose of short term exogenous D
WTAP/IGF2BP3 mediated m6A modification of the EGR1/PTEN axis regulates the malignant phenotypes of endometrial cancer stem cells PMID 39044249
Fatty acid binding protein 3 deficiency limits atherosclerosis development via macrophage foam cell formation inhibition PMID 34370993
Neutrophil
NAD(P)H quinone oxidoreductase 1 (NQO1)
Nutlin
Microfibrillar
FTO/RUNX2 signaling axis promotes cementoblast differentiation under normal and inflammatory condition PMID 36084732
PPARα activation protects against cholestatic liver injury PMID 28855630
Irak3 Rat Pre
Regulatory Role of eIF2αK4 in Amino Acid Transporter Expression in Mouse Brain Capillary Endothelial Cells PMID 39532778
WP1066 disrupts Janus kinase
AI
Vitamin A
ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1 PMID 37170317
GLUT1
Inhibition of rho
Discovery of Darovasertib (NVP
Dioscin attenuates lupus nephritis in NZB/W F1 mice by decreasing NF
MCE
CHD7 regulates bone
The protective effect of high mobility group protein HMGA2 in pressure overload
Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK) PMID 10465550
Host stimulator of interferon genes is essential for the efficacy of anti
Stress
Functional analysis of the ube3a response in Japanese flounder (Paralichthys olivaceus) to CSBV infection PMID 38461876
Up
Synergistic Activity of Fluoroquinolones Combining with Artesunate Against Multidrug
ZKSCAN8 Human Pre
Boronate
Circulating mitochondrial DNA promotes M2 polarization of tumor associated macrophages and HCC resistance to sorafenib PMID 40038250
Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2 PMID 9145919
Hepatocyte Ninjurin2 promotes hepatic stellate cell activation and liver fibrosis through the IGF1R/EGR1/PDGF
The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice PMID 27031333
Targeting the NF
Discovery of 4
Heart rates, breathing rates and the effects of atropine and acetylcholine on white
Off
CK2 blockade causes MPNST cell apoptosis and promotes degradation of β
CircNOX4 promotes proliferation and resistance by regulating the hsa
Tumor cell density regulates matrix metalloproteinases for enhanced migration PMID 30220965
Polyisoprenylated methylated protein methyl esterase a putative biomarker and therapeutic target for pancreatic cancer PMID 24852279
Effect of beta
Design, synthesis and biological evaluation of a new series of imidazothiazole
Cornuside alleviates psoriasis
rRNA intermediates coordinate the formation of nucleolar vacuoles in C. elegans PMID 37537842
Tauroursodeoxycholic acid alleviates hepatic ischemia reperfusion injury by suppressing the function of Kupffer cells in mice PMID 30119197
Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle
Anomeric Fatty Acid Functionalization Prevents Nonenzymatic S
HSP90α Mediates Sorafenib Resistance in Human Hepatocellular Carcinoma by Necroptosis Inhibition under Hypoxia PMID 33440739
COL6A2 Human Pre
PARP1 Inhibition Radiosensitizes Models of Inflammatory Breast Cancer to Ionizing Radiation PMID 31413177
Unique arginine array improves cytosolic localization of hydrocarbon
D3S
GDF15 promotes glioma stem cell
Neratinib enhances the efficacy of CDK4/6 inhibitor plus endocrine therapy in HR+/HER2
WT161, a selective HDAC6 inhibitor, decreases growth, enhances chemosensitivity, promotes apoptosis, and suppresses motility of melanoma cells PMID 39821335
Exogenous Ganglioside GT1b Enhances Porcine Oocyte Maturation, Including the Cumulus Cell Expansion and Activation of EGFR and ERK1/2 Signaling PMID 32046393
General Synthetic Method for Si
Combined Inhibition of ATR and WEE1 as a Novel Therapeutic Strategy in Triple
LW6, a hypoxia
PCSK1N as a tumor size marker and an ER stress response protein in corticotroph pituitary adenomas PMID 39288010
Inhibition of PI3K/Akt/NF
Ulex Europaeus Agglutinin I (UEA I)
CircRNA ATF6 suppresses bladder cancer cell proliferation and migration via miR
Fibroblast Activation Protein
Myc
A detrimental role of NLRP6 in host iron metabolism during Salmonella infection PMID 34942528
Quantification of five intracellular and extracellular methionine pathway intermediates using stable isotope dilution UHPLC
Transcriptome comparative analysis of amygdala
Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons PMID 35240008
LMX1A Human Pre
Interleukin
Administration of cyclophosphamide changes the immune profile of tumor
MKI67 Human Pre
Fumonisin+B+2
KIAA1429
Ugdh Rat Pre
JAK1 蛋白, Human (Active, sf9, GST)
urothelial+carcinoma
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases PMID 15323567
MRS1220 (Standard)
Rpgr
细胞色素 c 氧化酶亚基 6A2（COX6A2）基因
GIPR antagonist 1 3059497
CRT0083914 932495
His185
Molecular imaging, pharmacokinetics, and dosimetry of In
2,5
Nucleotide sequence and expression of rat beta
10(R)
venodilating
2
RGH
L
CPI 975
Upregulation of immunoreactive angiotensin II release and angiotensinogen mRNA expression by high
Hydroxychloroquine impurity 2 47493
Folh1
cyclic voltammetry
Protein modules that manipulate histone tails for chromatin regulation PMID 11389466
IRBM
含 C 型凝集素结构域 6A（CLEC6A）基因
Hedgehog regulates Norrie disease protein to drive neural progenitor self
CRT0093964 700856
Thelenotoside B 72175
Cy5
PEDA 247096
Fmoc
HCN2 modulator
Cy3
Primisulfuron
PSNCBAM
PSB
Four
MCE
Cetoniacytone A 496775
CRT0083914
HSC mobilizer
Polytetrafluoroethylene
Chantriolide C 1206850
ARL5B Human Pre
Possible involvement of long chain fatty acids in the spores of Ganoderma lucidum (Reishi Houshi) to its anti
JRN73958 171773
(R,S)
DSM 267
ADAM8
AKT 丝氨酸/苏氨酸激酶 1（Akt1）基因
ST91 4749
Simple avarone mimetics as selective agents against multidrug resistant cancer cells PMID 27128177
Suppression of Medulloblastoma Lesions by Forced Migration of Preneoplastic Precursor Cells with Intracerebellar Administration of the Chemokine Cxcl3 PMID 28018222
2α,3α,24
Basiliximab
Fhl2
AMBA 721937
RM
免疫抑制 (Immunosuppression)
UiO 67 1072413
MCE
MCE
Avenanthramide L 172549
Acid
MOFs
4030W92
Cys
GLK7
(R,S)
antisense applications
[Rh(cod)Cl]2
immunodeficient mice
SCH
MOFs
Pentamidine
Ce 6
Molecular docking and molecular dynamics to identify collagenase inhibitors as lead compounds to address osteoarthritis PMID 33103592
Kif3b
T 盒转录因子 5（TBX5）基因
mmu
细胞色素 c 氧化酶亚基 6A1（COX6A1）基因
AMBA
VI 型胶原蛋白 alpha 2 链（COL6A2）基因
RNA modification
MCE
P70 S6 Kinase beta/SRK (phospho S371) 抗体 (YA1890)(PBS only)（P70 S6 Kinase beta/SRK (phospho S371) Antibody (YA1890)(PBS only)）
Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components PMID 21209331
氧阿苯达唑
Lep Rat Pre
Lamp1 Mouse Pre
BWA
MCE
EDA2R Human Pre
Antitubercular activity of triterpenoids from Asteraceae flowers PMID 15635183
Derritol
Hexaprofen 24645
CaMKII beta 抗体 (YA2344)(PBS only)（CaMKII beta Antibody (YA2344)(PBS only)）
氧阿苯达唑
Azido
HCN2 modulator
BMY
Ctnna1 Rat Pre
Novel low
Thiocarbonyldiimidazole
2,5
GLMN Human Pre
Commiphora mukul extract
Piper longum fruit extract
Induced cross
Steffimycin B 54526
4
nano
Arg265
Sema6a Mouse Pre
Anorectal malformations caused by defects in sonic hedgehog signaling PMID 11485934
Commiphora mukul extract 93165
Volatile oil composition of Carthamus Tinctorius L. flowers grown in Kazakhstan PMID 29575869
Study on gluco
Benzophenone derivatives from the fruits of Garcinia multiflora and their anti
MUC15
Cbx5 Rat Pre
HCN2 modulator
1
MCE
Memnobotrin A 256235
COX6B1 Human Pre
Pharmacokinetic differences between the enantiomers of lansoprazole and its metabolite, 5
Synthesis of five libraries of 6,5
Crosstalk between hypoxia
Primordazine B
Ac
Netrin receptor DCC/DCC 蛋白, Human (HEK293, Fc)
Bet1 高尔基体囊泡膜运输蛋白样（BET1L）基因
Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells PMID 29988067
HCN2
Fap Rat Pre
Formation of a highly stable complex between BN 50730 [tetrahydro
21
Antiproliferative agent
DCP
SIK1/SIK
Pxn
Synthesis and structural studies of pentacycloundecane
In
OX40 Ligand/TNFSF4 Trimer 蛋白, Human (HEK293, His
MCE
Synergistically dual
New stable butyrate derivatives alter proliferation and differentiation in human mammary cells PMID 2040538
Protoapigenin 879325
SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway PMID 35800779
Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis PMID 38225213
CD147 mitochondria translocation induced airway remodeling in asthmatic mouse models by regulating M2 macrophage polarization via ANT1
3
DB04760 544678
SCH
TBL1X/Y 相关 1（TBL1XR1）基因
BACE1 蛋白, Human (HEK293, Fc)
Exopolysaccharides from Lactobacillus plantarum NCU116 Enhances Colonic Mucosal Homeostasis by Controlling Epithelial Cell Differentiation and c
The Multi
Multivalent mannose
1
Identification of 4
Concomitant aortic root and pectus deformity repair in Marfan syndrome patients PMID 30136630
Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non
(S)
Gut Bacteroides ovatus ameliorates renal fibrosis by promoting the production of HDCA through upregulation of Clostridium scindens PMID 39392759
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2
Astragaloside IV Ameliorates Isoprenaline
DPPC
N
Influenza A(H1N1)pdm09 virus resistance to baloxavir, oseltamivir and sialic acid mimetics in single and dual therapies Insights from human airway epithelia and murine models PMID 40324597
An In Vitro TORC1 Kinase Assay That Recapitulates the Gtr
SOS1
SPSB3 Human Pre
Global structure and dynamics of human apolipoprotein CII in complex with micelles evidence for increased mobility of the helix involved in the activation of lipoprotein lipase PMID 12590574
[Indolepatterns in the urine of liver patients] PMID 13905029
Cooperation between SIX1 and DHX9 transcriptionally regulates integrin
Pharmacodynamics of Akt drugs revealed by a kinase
Bioactive diterpenoids from Trigonostemon chinensis Structures, NO inhibitory activities, and interactions with iNOS PMID 27570243
MCE
Effective control of large deletions after double
Naringin targets Zeb1 to suppress osteosarcoma cell proliferation and metastasis PMID 30580326
'Mito
High glucose
d
CPI1 3085809
A broad
KN026 (anti
PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma PMID 36823188
Derritol 3276
5
Imidazoleacetic acid
CD3 delta 蛋白, Cynomolgus (HEK293, Fc)
Transient receptor potential vanilloid
Selective targeting of the IL23 pathway Generation and characterization of a novel high
Antitumor benzothiazoles. 16. Synthesis and pharmaceutical properties of antitumor 2
CRBN ligand
Exosomal PD
Vornorexant 1517965
Terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase PMID 10051623
Acid blue 260 67827
D
Heneicosanoic acid 2363
Omarigliptin 1226781
FOL7185 5441
Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor PMID 29978938
hiCE inhibitor
Lactiplantibacillus plantarum extracellular vesicles exert anti
DLX2
DTPA
Alloferon 2 347884
Brain and muscle redox imbalance elicited by acute ethylmalonic acid administration PMID 26010931
Non
New selective cytotoxic diterpenylquinones and diterpenylhydroquinones PMID 11312925
SARS
Novel tacrine
Dissecting the process of human neutrophil lineage determination by using alpha
Antennapedia Peptide, amide 214556
Targeting CD39 boosts PD
Single
PACS2 is required for ox
AA
PAIR2 2771006
Platycodin D, a novel activator of AMP
4
Technical Support
β
Identification of broad
UDP
Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog
NS2B/NS3
D
SB
ZW49
Virus
N
Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents PMID 21458275
Targeting Cavity
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance PMID 35165418
AKR1B10 dictates c
m
Gpr119 Rat Pre
WAY
Tinnevellin glucoside
Rapid Plastic Deformation of Cancer Cells Correlates with High Metastatic Potential PMID 35014196
Choloylglycine hydrolase 37289
Direct conversion of theophylline to 3
Pulrodemstat (hydrochloride) 1821307
Exosomes derived from bone mesenchymal stem cells attenuate myocardial fibrosis both in vivo and in vitro via autophagy activation the key role of miR
(Rac)
BM
JNK inhibitor and ferroptosis modulator as possible therapeutic modalities in Alzheimer disease (AD) PMID 39375359
Salidroside Inhibits α
Novel 5
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