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Selenenylsulfide covalent
3
protein functionalization
Evaluation of the Presence and Levels of Enrofloxacin, Ciprofloxacin, Sulfaquinoxaline and Oxytetracycline in Broiler Chickens after Drug Administration PMID 27846314
Membrane attack complex impairs hepatocyte autophagy in alcohol
Artesunate attenuates osteoarthritis in mice by promoting MTA1 transcription through a USP7/FoxO1 axis PMID 39173720
Tau seeding in neurons enabled by transient endolysosomal perforations are confined within endolysosomes PMID 41278722
Netrin
Anaphylactic reaction to isosulfan blue used for sentinel node biopsy case report and literature review PMID 12390368
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands PMID 10748001
Glycosylation
Neutrophil extracellular traps impede cancer metastatic seeding via protease
A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS PMID 37856217
Pharmacology of Adenosine Receptors The State of the Art PMID 29848236
Cbz
IL
LNA
An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1 PMID 23614352
Intramyocardial injected human umbilical cord
A combined in vitro and in silico study of the inhibitory mechanism of angiotensin
M1
Histamine H4 receptor antagonist
DBHDA (Standard)
Guar gum
GSK621 ameliorates lipid accumulation via AMPK pathways and reduces oxidative stress in hepatocytes in vitro and in obese mice in vivo PMID 40334907
Identification of HUHS190, a human naftopidil metabolite, as a novel anti
Targeting a Radiosensitizing Antibody
Quantitative mass spectrometry combined with separation and enrichment of phosphopeptides by titania coated magnetic mesoporous silica microspheres for screening of protein kinase inhibitors PMID 22304342
Internal Structure and Preferential Protein Binding of Colloidal Aggregates PMID 27983786
Novel Anti
The angiogenic factor Egfl7 alters thymogenesis by activating Flt3 signaling PMID 28601636
Fluoride resistance capacity in mammalian cells involves global gene expression changes associate with ferroptosis PMID 37245782
USP7 Inhibitors Destabilize EBNA1 and Suppress Epstein
Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance PMID 26041698
The effect of nanoparticle size, shape, and surface chemistry on biological systems PMID 22524388
Multifunctional nanoparticle platform for targeted delivery and vaccines PMID 40496813
Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids
Novel naftopidil
Novel 3,5
The phosphorylation status of Hsp82 regulates mitochondrial homeostasis during glucose sensing in Saccharomyces cerevisiae PMID 37068581
In Vitro and In Vivo Efficacy of the Monocarboxylate Transporter 1 Inhibitor AR
MAO
Raltegravir the first HIV type 1 integrase inhibitor PMID 19231980
Design, synthesis, and preliminary studies of the activity of novel derivatives of N
FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model PMID 23056173
Holo
CNIH3 Human Pre
Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase PMID 29691401
MALT1 protease inhibition restrains glioblastoma progression by reversing tumor
VU6043653 3032791
Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion PMID 38060985
RFPL3 蛋白, Human (His)
Sauchinone a prospective therapeutic agent
Jatrorrhizine Exhibits an Antitumor Effect Against Gefitinib
EFHD2 suppresses intestinal inflammation by blocking intestinal epithelial cell TNFR1 internalization and cell death PMID 38346956
Synthesis and evaluation of 1
Autophagy is involved in Ficus carica fruit extract
Haloperidol versus placebo for schizophrenia PMID 17054159
RIFM fragrance ingredient safety assessment, methyl acetoacetate, CAS Registry Number 105
LXR as a novel antithrombotic target PMID 21411760
Discovery of New HER2 Inhibitors via Computational Docking, Pharmacophore Modeling, and Machine Learning PMID 39976334
Lipidomic profiling of bile in distinguishing benign from malignant biliary strictures a single
Mechanisms of autophagy and endoplasmic reticulum stress in the reversal of platinum resistance of epithelial ovarian cancer cells by naringin PMID 37326754
Estrogen Acts Through Estrogen Receptor
One new galloyl glycoside from fresh leaves of Psidium guajava L PMID 21348423
Investigating the mechanism of Gentiopicroside in rheumatoid arthritis through network pharmacology, molecular docking, and experimental validation PMID 40473698
Genome
β
Trace Amine
Effect of 2
Prognosis of Midkine and AT1R expression in resectable head and neck squamous cell carcinoma PMID 37743493
Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein(a) Formation A Randomized Clinical Trial PMID 37638695
A c
Cancer
AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo PMID 17495131
eIF4EBP3 抗体 (YA5315)（eIF4EBP3 Antibody (YA5315)）
CBC
Phagocyte activation by Trp
Susceptibilities of genotype 1a, 1b, and 3 hepatitis C virus variants to the NS5A inhibitor elbasvir PMID 26303801
The mitotic checkpoint is a targetable vulnerability of carboplatin
ZG16B Human Pre
Smad1/5 is acetylated in the dorsal aortae of the mouse embryo before the onset of blood flow, driving early arterial gene expression PMID 39253943
β
Naringin alleviates acetaminophen
2D MXene Nanosheets with ROS Scavenging Ability Effectively Delay Osteoarthritis Progression PMID 39404298
Evaluation of metalloprotease inhibitors on hypertension and diabetic nephropathy PMID 21228113
Iron compounds catalyze the oxidation of 10
MUC1 mucin core protein binds to the domain 1 of ICAM
Identification and characterization of a new type of inhibitor against the human immunodeficiency virus type
2,4(5)
The protective effects of GLP
Increased Smooth Muscle Kv11.1 Channel Expression in Pulmonary Hypertension and Protective Role of Kv11.1 Channel Blocker Dofetilide PMID 31839145
Deciphering melanophagy role of the PTK2
Syntheses and cellular investigations of 17(3)
Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model PMID 24927406
BAFF 抗体 (YA1510)（BAFF Antibody (YA1510)）
N
C9orf72 抗体 (YA4623)（C9orf72 Antibody (YA4623)）
Targeting MAPK Signaling Loureirins A and B from Dracaena Loureiri Inhibit Epithelial
MCE
Angiotensin
Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA PMID 28570818
The E3 ubiquitin ligase adaptor KLHL8 targets ZAR1 to regulate maternal mRNA degradation in oocytes PMID 40721554
OSW
Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2
The SPI1/SMAD5 cascade in the promoting effect of icariin on osteogenic differentiation of MC3T3
Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase PMID 21796150
CDK4/6 inhibitor
ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS
ICOSLG Human Pre
Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors PMID 16207832
Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension PMID 35473584
Oral exposure to ovalbumin alters glucose metabolism in sensitized mice upregulation of HIF
LY2940094, an NOPR antagonist, promotes oligodendrocyte generation and myelin recovery in an NOPR independent manner PMID 39004556
Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT PMID 40642900
MCE
A Review of the Clinical Trial Landscape in Psoriasis An Update for Clinicians PMID 36319883
Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple
Design, Synthesis, and Evaluation of a Novel Conjugate Molecule with Dopaminergic and Neuroprotective Activities for Parkinson's Disease PMID 38991155
The inhibitory action of long
N
Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo PMID 15994763
Design, synthesis, and biological evaluation of aromatic tertiary amine derivatives as selective butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease PMID 36084535
G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer PMID 32989225
Role of timp2 in Ctenopharyngodon idellus muscle collagen deposition and the regulatory mechanism by Cu2 PMID 41140839
Cure of Micrometastatic B
Indeno[1,2,3
Pyroptosis induced by TLR9 ligand, ODN1826, requires ROS production and caspase
Biodecolorization of Naphthol Green B dye by Shewanella oneidensis MR
In vitro and in vivo killing of acute lymphoblastic leukemia cells by L
Assessment of Pharmacokinetics and Metabolism Profiles of SCH 58261 in Rats Using Liquid Chromatography
Exendin(9
3,5
Synthesis and evaluation of cardiac glycoside mimics as potential anticancer drugs PMID 21421322
Changes of dopamine content and cell proliferation by dexamethsone via pituitary adenylate cyclase
Pharmacokinetic basis for the comparative antitumour activity and toxicity of chlorambucil, phenylacetic acid mustard and beta, beta
NLRP3 selectively drives IL
Potential of muvalaplin as a lipoprotein(a) inhibitor PMID 38186354
Two new cytotoxic diterpenes from the rhizomes of Hedychium spicatum PMID 19027298
The effects of L
Effects of isopropyl palmitate on the skin permeation of drugs PMID 17077540
Pharmacological inhibition of cGAS ameliorates postoperative cognitive dysfunction by suppressing caspase
S3969 1027997
Quantitative Analysis of Phenylpropanoid Glycerol Glucosides in Different Organs of Easter Lily (Lilium longiflorum Thunb.) PMID 25905571
Design, synthesis and discovery of 5
Passive Immunization With a Novel Monoclonal Anti
Design, synthesis and antitumor activity of 4
Betaine promotes the osteogenic differentiation of SCAPs via inhibiting NUMB PMID 40974710
Triggering mitotic catastrophe by podophyllotoxin induces apoptosis in oral squamous cell carcinoma PMID 40966849
hsa
ARF6 inhibition stabilizes the vasculature and enhances survival during endotoxic shock PMID 24835390
Binding of interleukin
Terazosin, a repurposed GPR119 agonist, ameliorates mitophagy and β
In vivo efficacy of XR9051, a potent modulator of P
Picomolar Inhibitors of HIV
Inhibition of Bcl
JND3229 2260886
Dexmedetomidine Inhibits NF
Activating a collaborative innate
Effects of transforming growth factor
Cited2 is required both for heart morphogenesis and establishment of the left
Anti
miR
Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A
Extracellular CIRP Induces Inflammation in Alveolar Type II Cells via TREM
N
Antinociceptive activity of the selective iNOS inhibitor AR
Development of novel rivastigmine derivatives as selective BuChE inhibitors for the treatment of AD PMID 39954353
Novel MSH2 and TSC2 variants in a Chinese family with Lynch syndrome and their synergistic impact in urothelial carcinoma PMID 37914149
Fam89b
FASN
BCL7A inhibits the progression and drug
Inhibition of cartilage degradation in rat collagen
Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases PMID 16872140
Hybrid Cell Membrane
Inflammatory signaling attenuates spliceosome function and cognitive ability PMID 40963239
Novel Compound Heterozygous Variations in MPDZ Gene Caused Isolated Bilateral Macular Coloboma in a Chinese Family PMID 36429029
Lakoochins A and B, new antimycobacterial stilbene derivatives from Artocarpus lakoocha PMID 15043440
Discovery of Selective Small Molecule Inhibitors of Monoacylglycerol Acyltransferase 3 PMID 26258602
Antitumor effects of β
Depletion of protein thiols and the accumulation of oxidized thioredoxin in Parkinsonism disclosed by a red
Ultrastructural Changes of the Right Ventricular Myocytes in Pulmonary Arterial Hypertension PMID 30807241
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms PMID 25043017
production performance
Global identification of SWI/SNF targets reveals compensation by EP400 PMID 37922899
The Asparaginyl Endopeptidase Legumain An Emerging Therapeutic Target and Potential Biomarker for Alzheimer's Disease PMID 36142134
Biphenyl Acid Derivatives as APJ Receptor Agonists PMID 31724863
3
S0859 1019331
Mucosal healing effect of nilotinib in indomethacin
Antitumor Activity of KW
Activin A alleviates neuronal injury through inhibiting cGAS
golgin A7 家族成员 B（GOLGA7B）基因
HA1/Hemagglutinin 蛋白, H1N2 (AAY28987, HEK293, His)
Pharmacological inhibition of DKK1 promotes spine fusion in an ovariectomized rat model PMID 35688363
Synthesis and anticancer activity evaluation of a series of [1,2,4]triazolo[1,5
Proteomics analysis reveals FEN1 as a promising therapeutic target against small cell neuroendocrine carcinoma of the cervix PMID 40739179
Per
Targeting Androgen Receptor Activation Function
Tumor cell
Antibacterial action of 2
Potential of CLSPN as a therapeutic target in melanoma a key player in melanoma progression and tumor microenvironment PMID 40275302
Premature ovarian failure a critical condition in the reproductive potential with various genetic causes PMID 24696764
Synthesis of novel 10
In vivo demonstration of M3 muscarinic receptor subtype selectivity of darifenacin in mice PMID 16996089
Astragaloside II, a natural saponin, facilitates remyelination in demyelination neurological diseases via p75NTR receptor mediated β
Annexin A1 (Ac2
HDAC6 deacetylates ENKD1 to regulate mitotic spindle behavior and corneal epithelial homeostasis PMID 40155750
Synthesis and biological evaluation of novel 6
De Novo Design of Nurr1 Agonists via Fragment
Fmoc
SARS
PKR
Sincalide A Review of Clinical Utility, Proper Infusion Methodology, and Alternative Cholecystogogues PMID 31019045
Targeting Tumor Necrosis Factor
A Therapeutic Whole
Konjac Oligosaccharide Alleviates Constipation in Mice via 5
Isolation and biochemical characterization of LEAP
MCE
EDA Human Pre
MCE
Ca2+/calmodulin
Blockage of Cholinergic Signaling via Muscarinic Acetylcholine Receptor 3 Inhibits Tumor Growth in Human Colorectal Adenocarcinoma PMID 34203220
Safety, Pharmacokinetics, and Pharmacodynamic Effects of a Selective TGR5 Agonist, SB
Design and synthesis of N
Cstf2 Mouse Pre
Anthraquinone Glycoside Aloin Induces Osteogenic Initiation of MC3T3
Small molecule branched
DNA adduct formation and mutant induction in Sprague
5'
Peptides with Soft
Inhibition of mammalian target of rapamycin signaling by 2
N6
Divalent metals and pH alter raltegravir disposition in vitro PMID 22450971
Efficacies of albendazole sulfoxide and albendazole sulfone against In vitro
TMSB4Y restrains sphingomyelin synthesis via de novo purine synthesis to exert a tumor suppressor function in male esophageal squamous cell carcinoma PMID 39443723
McN3716 69207
Octahydroisoindole 21850
Trimethobenzamide 138
Eda Rat Pre
CRBN ligand
Discovery and Optimization of Potent and CNS Penetrant M5
Gprc6a Mouse Pre
Monitoring ATP dynamics in electrically active white matter tracts PMID 28414271
NKp44/NCR2 蛋白, Human (HEK293, His)
Synthesis of novel guttiferone A derivatives in
AR antagonist 2
FAK
Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin
Anti
Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age
The deubiquitinating enzyme UCHL1 promotes resistance to pemetrexed in non
Design and synthesis of novel thiobarbituric acid derivatives targeting both wild
Structural requirements for inhibitory effects of bisphenols on the activity of the sarco/endoplasmic reticulum calcium ATPase PMID 23643898
Cep55
Influence of three coccidiostats on the pharmacokinetics of florfenicol in rabbits PMID 25319758
NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury in db/db mice PMID 23826864
Three
(Rac)
Synthesis of 2,3
1
Canagliflozin inhibits inflammasome activation in diabetic endothelial cells
(S)
Preclinical and clinical development of deferitrin, a novel, orally available iron chelator PMID 16339704
BGP
Phase II trial of dacarbazine (DTIC) in advanced pancreatic islet cell carcinoma. Study of the Eastern Cooperative Oncology Group
Repurposing the mucolytic cough suppressant and TMPRSS2 protease inhibitor bromhexine for the prevention and management of SARS
8beta
Oxytocin mediates copulation
Developmental toxicity study of lersivirine in mice PMID 22447726
G3BP1 maintains endothelial barrier integrity through dual mechanisms direct stabilization of junction protein mRNAs and suppression of the inflammatory MYD88
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp
Dicaprylyl carbonate 1680
Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene PMID 16391197
Design, synthesis, and evaluation of 2
AI
Cytotrophoblasts suppress macrophage
Discovery of Novel Imidazo[4,5
The MT1G Gene in LUHMES Neurons Is a Sensitive Biomarker of Neurotoxicity PMID 32870474
2,2'
A proteomics strategy for the enrichment of receptor
The effect of oral calcitonin on cartilage turnover and surface erosion in an ovariectomized rat model PMID 17665432
Ro 48
Discovery of RG7112 A Small
N
Kasugamycin sulfate 78822
Boc
AZGP1 蛋白, Human (HEK293, His)
Myeloperoxidase Inhibition in Heart Failure With Preserved or Mildly Reduced Ejection Fraction SATELLITE Trial Results PMID 37072105
Generation and exploration of new classes of antitubercular agents The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2
TIM3/CEACAM1 pathway involves in myeloid
Inhibition of beta
MCE
Inhibition of lipopolysaccharide
Giardia duodenalis extracellular vesicles regulate the proinflammatory immune response in mouse macrophages in vitro via the MAPK, AKT and NF
Huaier inhibits autophagy and promotes apoptosis in T
FGL1 蛋白, Cynomolgus (HEK293, mFc)
TLR4
Calcium and integrin binding protein 1 (CIB1) induces myocardial fibrosis in myocardial infarction via regulating the PI3K/Akt pathway PMID 34349085
Maleimido
Advancing the Adverse Outcome Pathway for PPARγ Inactivation Leading to Pulmonary Fibrosis Using Bradford
Mangostanol 184587
Norbixin, a natural dye that improves serum lipid profile in rabbits and prevents LDL oxidation PMID 35940777
miR
Tumor
Tumor
Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge PMID 31462679
2
无名指蛋白 130（RNF130）基因
PyP
AS1468240 365462
Epinastine, a highly specific antagonist of insect neuronal octopamine receptors PMID 9671095
Reprogramming of cancer
IL
SETDB1 tumour suppressor roles in near
CRBN ligand
Investigating STEAP2 as a potential therapeutic target for the treatment of aggressive prostate cancer PMID 37329528
A drug discovery platform to identify compounds that inhibit EGFR triple mutants PMID 32094923
The inhibition of beta
USP20
Alternations of Blood Pressure Following Surgical or Drug Therapy for Prolactinomas PMID 38398117
Engineered Apoptosis
MCE
CD44 fucosylation on bone marrow
Cox6b1 Mouse Pre
Central nervous system disposition and metabolism of Fosdevirine (GSK2248761), a non
CDK1 substitutes for mTOR kinase to activate mitotic cap
短腺小米草提取物 (Euphrasia regelii Wettst.)
AG 1406 71308
TOLLIP inhibits the replication of PEDV by autophagic degradation of Nsp9 PMID 39909271
Convertible Hydrogel Injection Sequentially Regulates Diabetic Periodontitis PMID 39792458
A Phase I Study of FOLFIRINOX Plus IPI
Identification of substituted 6
The Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type
PZM21 (Standard)
Corrected structure of mirin, a small
Ulefnersen 2589926
Chemokine release from human rhinovirus
Tnxb Mouse Pre
Effects of Empagliflozin and Dapagliflozin in alleviating cardiac fibrosis through SIRT6
Collagen alpha
Lanopylins A1, B1, A2 and B2, novel lanosterol synthase inhibitors from Streptomyces sp. K99
Diallyl trisulfide inhibits naphthalene
New therapeutic targets for mood disorders PMID 20419280
Synthesis and pharmacological investigation of segetalin C as a novel antifungal and cytotoxic agent PMID 18368948
CFAP53
Pharmacological characterization of M
Compressive Force Inhibits Osteogenic Differentiation of Dental Follicle Stem Cells Through Biglycan/Bone Morphogenetic Protein2/Smad1 Signaling Pathway PMID 40395190
视黄酸受体γ（RARG）基因
Synthesis, biological evaluation and molecular modeling studies of psammaplin A and its analogs as potent histone deacetylases inhibitors and cytotoxic agents PMID 27460171
SB
The RNA
COX
Bioinformatics analysis and experimental validation of potential targets and pathways in chronic kidney disease associated with renal fibrosis PMID 40176090
Acetylcholine exerts inhibitory and excitatory actions on mouse ileal pacemaker activity role of muscarinic versus nicotinic receptors PMID 32475128
JUP/plakoglobin is regulated by salt
Tanshinone IIA ameliorates Aβ transendothelial transportation through SIRT1
Differential effects of alpha
Xanthohumol induces paraptosis of leukemia cells through p38 mitogen activated protein kinase signaling pathway PMID 28415750
Plasticity of the mammalian integrated stress response PMID 40140574
The photosensitizer verteporfin has light
Vigabatrin for focal drug delivery in epilepsy bilateral microinfusion into the subthalamic nucleus is more effective than intranigral or systemic administration in a rat seizure model PMID 22342648
Discovery of novel 2,3
Neutralizing IL
Ferristatin II protects nucleus pulposus against degeneration through inhibiting ferroptosis and activating HIF
Multicellular Bioprinting of Biomimetic Inks for Tendon
A new sensitive method for qualitative and quantitative assay of neomycin phosphotransferase in crude cell extracts PMID 6096215
Synthesis and antimalarial activity of quinones and structurally
iSoMAs Finding isoform expression and somatic mutation associations in human cancers PMID 40053523
Biomimetic Biomembrane Encapsulation and Targeted Delivery of a Nitric Oxide Release Platform for Therapy of Parkinson's Disease PMID 37040524
NDUFS8 抗体 (YA1352)（NDUFS8 Antibody (YA1352)）
Cannabidiol Enhances Microglial Beta
Immune effects of R848 evidences that suggest an essential role of TLR7/8
Dynamic STING repression orchestrates immune cell development and function PMID 40053603
10
Mode of action and quantitative structure
Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy PMID 18594008
(+)
1,4
A functionalized hydroxydopamine quinone links thiol modification to neuronal cell death PMID 31760358
CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms PMID 26175413
Efficacy and safety of the monoclonal anti
2
Phytochemical profiling of Symplocos tanakana Nakai and S. sawafutagi Nagam. leaf and identification of their antioxidant and anti
Action of the antidepressant pridefine (AHR
Activation and signaling mechanism revealed by GPR119
Teicoplanin
Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1
Evaluation of a bivalent recombinant vaccine candidate targeting norovirus and rotavirus Antibodies to rotavirus NSP4 exert antidiarrheal effects without virus neutralization PMID 35474320
Glut3 promotes cellular O
Fructose
Thiocarbonyldiimidazole 6160
Simultaneous determination of seven bioactive lignans in Herpetospermum caudigerum by RP
Baicalin attenuates pulmonary hypertension by targeting AMPK/CPT1A
DLK
Decaffeoylacteoside 61548
Farnesol 4602
MCE
Effect of GABA
Neurofilament light polypeptide 抗体 (YA1961)（Neurofilament light polypeptide Antibody (YA1961)）
ATP
Icariin promotes osteogenic differentiation of bone marrow stromal cells and prevents bone loss in OVX mice via activating autophagy PMID 30887562
Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture PMID 27562210
The orofacial capsaicin test in rats effects of different capsaicin concentrations and morphine PMID 11932064
Hypoglycemic effects of a novel fatty acid oxidation inhibitor in rats and monkeys PMID 9486313
Alkaloids from Gelsemium elegans PMID 16989532
lymphatic system
Nociceptor
Development and validation of a liquid chromatography tandem mass spectrometry assay for AZD3965 in mouse plasma and tumor tissue Application to pharmacokinetic and breast tumor xenograft studies PMID 29674138
Synthesis of enamino
(rac)
The protective and therapeutic effects of linalool against doxorubicin
Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine⁷⁹⁰ → methionine⁷⁹⁰ mutant PMID 22339342
Chloro(methyl)(phenyl)silane 1631
TGFβ1
Triapine (3
Preferential tumor targeting of HER2 by iPSC
The Inhibitory Effects of the Natural Stilbene Piceatannol on Lactate Transport In Vitro Mediated by Monocarboxylate Transporters PMID 39344244
GRF (1
GalNAc unconjugated/naked Fitusiran sodium
Interleukin
The contribution of a 2
Overcoming the On
Parvalbumin Interneuron Activation
Dendrobium officinale Kimura & Migo polysaccharide ameliorates skin photoaging by promoting angiogenesis PMID 40820014
Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits matrix metalloproteinase
Debrisoquin hemisulfate 581
Inhibition of ACSS2 attenuates alcoholic liver steatosis via epigenetically regulating de novo lipogenesis PMID 37183518
Inhibition of kynurenine production by N,O
Dysregulation of muscle cholesterol transport in amyotrophic lateral sclerosis PMID 39197036
Efficient Delivery of Lomitapide using Hybrid Membrane
TCF3 / E2A 抗体 (YA4819)（TCF3 / E2A Antibody (YA4819)）
Selective Killing of BRCA2
AKN028
MCE
Dapagliflozin alleviated obesity
MCE
PAX8 抗体 (YA5010)（PAX8 Antibody (YA5010)）
Imaging mitochondrial flux in single cells with a FRET sensor for pyruvate PMID 24465702
Effects of 5
VEGF
MCE
Dietary supplementation with 22
The mechanism of STING autoinhibition and activation PMID 37086726
Discovery of (E)
TLR7
Restriction of hepatitis B virus replication by c
Actl6a Mouse Pre
USP29 Human Pre
TGF
Engineered Hollow Nanocomplex Combining Photothermal and Antioxidant Strategies for Targeted Tregs Depletion and Potent Immune Activation in Tumor Immunotherapy PMID 40109122
Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3
NUF2 and NEK2 promote malignant progression of gallbladder cancer by remodeling the extracellular matrix PMID 40220284
Complement Molecule C3a Exacerbates Early Brain Injury After Subarachnoid Hemorrhage by Inducing Neuroinflammation Through the C3aR
Clinical and pharmacogenetics associated with recovery time from general anesthesia PMID 30136624
In Vivo Efficacy of SYN023, an Anti
Efficacy and Safety of Asparagusic Acid against Echinococcus multilocularis In Vitro and in a Murine Infection Model PMID 38787043
Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF
Brief reports Controlling the survival of human pluripotent stem cells by small molecule
Kirrothricin 79190
Dual drugs decorated bacteria irradiate deep hypoxic tumor and arouse strong immune responses PMID 35609407
BMS
A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers PMID 32203529
MEK3 抗体 (YA3214)(PBS only)（MEK3 Antibody (YA3214)(PBS only)）
Secretogranin III promotes angiogenesis through MEK/ERK signaling pathway PMID 29154827
Khayanolides from African mahogany Khaya senegalensis (Meliaceae) A revision PMID 19136128
5
ZLY032 mediated activation of Notch1/Hes1 signaling inhibits cardiomyocyte ferroptosis to protect against myocardial Ischemia
Hexaminolevulinate
Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti
The expression of kappa
A phase I dose
Discovery of BLU
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells PMID 21743462
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED PMID 28135235
ERK5 kinase activity is dispensable for cellular immune response and proliferation PMID 27679845
Modulation of NLRP3 inflammasomes activation contributes to improved survival and function of mesenchymal stromal cell spheroids PMID 36566348
Comparison of N
Ultrasound‑targeted microbubble destruction technology delivering β‑klotho to the heart enhances FGF21 sensitivity and attenuates heart remodeling post‑myocardial infarction PMID 38666537
Pharmacophore elucidation for a new series of 2
MCE
IL
4
Safety, tolerability, pharmacokinetics and pharmacodynamics of a single intravenous dose of SHR
UNC0638 inhibits SARS
Towards new C6
Anti
Malfunction of astrocyte and cholinergic input is involved in postoperative impairment of hippocampal synaptic plasticity and cognitive function PMID 35835213
Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells PMID 38114514
Oleanane
Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling PMID 35864954
Quercetin Prevents Hyperuricemia Associated With Gouty Arthritis by Inactivating the NLRP3/NF
MCE
The mechanisms of multidrug resistance of breast cancer and research progress on related reversal agents PMID 37847948
Downregulating expression of OPTN elevates neuroinflammation via AIM2 inflammasome
Dihydromyricetin protects sevoflurane
Mal
A novel small
Slimming and Reinvigorating Tumor
Combination non
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