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NPI
Osthole 484
Leveraging quantum chemical properties in transfer learning for predicting blood
84513
CNTO
Examining the Role of the Linker in Bitopic N6
OXFBD03
Mechanism underlying the effects of doxepin on β
The ribotoxin restrictocin recognizes its RNA substrate by selective engagement of active site residues PMID 21417210
SL910102
OsMo
Effect of undecanoic acid on the production of exocellular lipolytic and keratinolytic enzymes by undecanoic acid
Retinoic acid enhances γδ T cell cytotoxicity in nasopharyngeal carcinoma by reversing immune exhaustion PMID 40158172
Decreased Glycolysis at Menstruation is Associated with Increased Menstrual Blood Loss PMID 36042151
Flestolol sulfate 88844
6
Dusp8 Mouse Pre
Inhibitory effects of sulfenimides on human and bovine carbonic anhydrase enzymes PMID 36971264
PD
m
Dioscin inhibits osteoclast differentiation and bone resorption though down
Total synthesis and biological evaluation of methylgerambullone PMID 19945876
Endogenous methionine enkephalin may play an anticonvulsant role in the seizure
Camphor sulfonic acid methyl ester (Methyl (1S)
MCE
Glycohyocholic acid (GHCA)
Tiemonium
DcR3/TNFRSF6B 蛋白, Human (HEK293, hFc)
Meeting organometallic chemistry with drug discovery CH activation enabled discovery of a new ring system of 12H
Resveratrol Attenuates Pressure Overload
A novel cell permeant and far red
PRKACA/PKAc alpha
Fas/CD95 蛋白, Mouse (HEK293, His)
Inactivation of the uterine estrogen receptor binding of estradiol during P
Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics PMID 21283799
Acadsb
STING
TP
Fmoc
Broxaterol a double
Biophysical characterization and antitumor activity of synthetic Pantinin peptides from scorpion's venom PMID 30409511
TIPP
Neuroprotective Compound from an Endophytic Fungus, Colletotrichum sp. JS
Making Protein Degradation Visible Discovery of Theranostic PROTACs for Detecting and Degrading NAMPT PMID 36442664
(Rac)
Dynamic phosphorylation of FOXA1 by Aurora B guides post
PRP020
1,2,4
Essential oil compositions of different accessions of Coriandrum sativum L. from Iran PMID 20803372
TORC3 抗体 (YA5086)(TORC3 Antibody (YA5086))
2′
2
TNK
BRD4 Inhibitor
RP
ML
Exploitation of the multitarget role of new ferulic and gallic acid derivatives in oxidative stress
NAPIE
Anastrozole impurity 10
Siamycins I and II, new anti
Discovery of small molecules for autophagy
The heterocyclic substituted pyridine derivative (+/
4
GLUT
Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP
AS
SAA4 Human Pre
Fmoc
2
Phenolic diterpenes from rosemary suppress cAMP responsiveness of gluconeogenic gene promoters PMID 22927089
Rivaroxaban impurity 67
Upregulation of circ_0076684 in osteosarcoma facilitates malignant processes by mediating miRNAs/CUX1 PMID 38659042
CREB 结合蛋白(Crebbp)基因
MeOSuc
MSTN
Got2 Rat Pre
FITC
RIT
Synthesis and SAR studies of benzyl ether derivatives as potent orally active S1P₁ agonists PMID 24909680
CGS
p
MLJS 21001
8
Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway PMID 24316735
GF 120918
DNA
Cardiovascular effects of NPK
Disrupting myddosome assembly in diffuse large B‑cell lymphoma cells using the MYD88 dimerization inhibitor ST2825 PMID 31432184
YPLP
Ultrasmall Enzyodynamic PANoptosis Nano
ClickRNA
Telmisartan impurity 2 612
Inhibition of Protein arginine methyltransferase 6 reduces reactive oxygen species production and attenuates aminoglycoside
Synthesis of dehydroabietic acid derivatives as mast cell stabilizers PMID 41242349
调节因子 X 相关蛋白(RFXAP)基因
Syp
Aspulvinone H 57744
Droseron
Glipr2 Mouse Pre
Zalcitabine 7481
Trididemnin
5’
Kif7 Mouse Pre
AM0216
LY237
Markedly improved efficacy of edatrexate compared to methotrexate in a high
Hexacyclic monoterpenoid indole alkaloids from Rauvolfia verticillata PMID 26474672
Dihydrocoptisine 53777
Lead optimization of 3
Discovery of a new inhibitor for YTH domain
Hypoxia
3
Free fatty acids induce bile acids overproduction and oxidative damage of bovine hepatocytes via inhibiting FXR/SHP signaling PMID 39053701
2,5
Droxicam a pharmacological and clinical review of a new NSAID PMID 1365488
RAB8B Human Pre
Chlorogenic acid improves diabetic retinopathy by alleviating blood
Benzaldehyde dimethyl acetal
t
Investigating the role of GTPase in inhibiting HBV replication and enhancing interferon therapy efficacy in chronic hepatitis B patients PMID 39084309
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin PMID 8181754
Development and validation of an UPLC
(2
闭合蛋白(OCLN)基因
Benzyl
EC
PNO1 蛋白, Human (His)
2
The GR
Rational Design of Novel pyrazolo[4,3
15
Novel Meso
Butaverine 55837
Acetazolamide impurity 1 (Standard)
Hecubine 62874
Cd247 Rat Pre
Brevilin A, a novel natural product, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells PMID 23704931
The metabolism of trans
CAAT
2,4
Skeletal muscle myosin and cardiac myosin attenuate heparin's antithrombin
p66shc exacerbates the progression of obstructive nephropathy through apoptosis, mitochondrial damage, and EMT PMID 40234179
MCE
Summary of safety evaluation toxicity studies of glufosinate ammonium PMID 2379893
Nuclear recruitment of A1p145 subunit of replication factor C in the early G1 phase of the cell cycle in Faza 567 hepatoma cell line and hepatocyte primary cultures PMID 7729533
DMNB
Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta
SIRT6 promotes angiogenesis by enhancing VEGFA secretion via demyristoylation in endothelial cell PMID 39753390
Multiple effects of anthracene
2
BMS
3'
6
SPARC 样 1(SPARCL1)基因
L
Sos2
Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism PMID 32847982
A sterile plant culture system of Uncaria rhynchophylla as a biosynthetic model of monoterpenoid indole alkaloids PMID 40636431
CD73/5'
MCE
Phosphodiesterase
Navitoclax
CB2R probe 1 2634714
HDAC
AP3B2 Human Pre
Antifungal agent
The hydrolysis of phenyl phosphate by mouse
Cytosolic phospholipase A2
ML 095
H
Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti
C8g
NPI2358
Calr
High
Ganoderic acid TR 862893
Anti
cis
Antitumor agents 288 design, synthesis, SAR, and biological studies of novel heteroatom
In vitro characterization of baloxavir acid, a first
m
KRAS takes the road to destruction PMID 39298611
Antiplatelet and antithrombotic effects of YM337, the Fab fragment of a humanized anti
跨膜蛋白 102(TMEM102)基因
L
Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE
Discovery and pharmacological characterization of a novel rodent
Platelet aggregation inhibitors from jyu
DX8951
Consequences of Dispersity on the Self
AM679
Serpin G1 蛋白, Mouse (HEK293, His)
5,10,15,20
Broad
Aberrant JAK
NVP
m
Ube2i
RELT 肿瘤坏死因子受体(RELT)基因
KEAP1 蛋白, Human (sf9, His
Structure
De novo development of small cyclic peptides that are orally bioavailable PMID 38155304
M1/M4 muscarinic agonist 3
Proton Pump
HBV
Baicalein sensitizes triple negative breast cancer MDA
RGD1306271
Mal
Gastrokine 1 蛋白, Human (sf9, His)
YM
Design, Synthesis, and Biological Evaluation of Rapamycin Derivatives as the First Mammalian Target of Rapamycin and GLS1 Dual Inhibitors PMID 41105615
The Long Noncoding RNA LINC02820 Promotes Tumor Growth and Metastasis Through Regulating MYH9 Expression in Esophageal Squamous Cell Carcinoma PMID 40416600
MTSS1 curtails lung adenocarcinoma immune evasion by promoting AIP4
Floridolide B 67517
astra
Gas chromatographic
Development of 3D
H
Newer antihistaminics III. Some pharmacologic and therapeutic effects of beta
3R
LY135305 123199
8
MNF
Pharmacologic Inhibition of Host Phosphodiesterase
Activation of the prostaglandin E2 EP2 receptor attenuates renal fibrosis in unilateral ureteral obstructed mice and human kidney slices PMID 31054202
Gria2
Synthesis of naphthoquinoles as potential antitumor agents related to jacaranone PMID 7130984
Kurarinone attenuates hydrogen peroxide
Inhibition of Escherichia coli ATP synthase by amphibian antimicrobial peptides PMID 20100509
The effects of jatrorrhizine on contractile responses of rat ileum PMID 21596029
Daphnetin triggers ROS
The COX
The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand
18 0
PIK
Molecular Recognition and Imaging of Human Telomeric G
Nrf2 activator
YM 13650
SM201
ClpP activator
ATP
A TrkB cleavage fragment in hippocampus promotes Depressive
Marine natural products and their potential applications as anti
Lupane
Antifungal agent 150
7
Microplastics exposure affects the feeding behavior of the whiteleg shrimp Litopenaeus vannamei by impairing the appetite, olfaction and digestion PMID 40680651
2
Identification and Tracking of Antiviral Drug Combinations PMID 33080984
Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3 PMID 25624051
a3
Nectin
Isorhynchophylline attenuates proliferation and migration of synovial fibroblasts via the FOXC1/β
Synthesis and antitumor activity of new shikonin glycosides PMID 20403646
Sennidin B 517
2
Benzyloxy carbonyl
hsa
Bis
Ebola virus Glycoprotein/GP 蛋白 RBD (AHX24649, HEK293, Fc)
Ambn Mouse Pre
Acadvl Mouse Pre
Ioversol (Standard)
3
(S)
MCE
MCE
SARS
MCE
Lycopodium alkaloids from Huperzia serrata PMID 31351127
FGF2 Mediated USP42
Metabolomics Based on UHPLC
PIM1 attenuates cisplatin
Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulation PMID 16330494
Lipoteichoic acid restrains macrophage senescence via β
Equisetin inhibits adiposity through AMPK
Effects of Compounds Isolated from Lindera erythrocarpa on Anti
Berberine alleviates acute embolism
Induction of RAGE shedding by activation of G protein
DDX60 protects ischemic myocardial injury and heart dysfunction by improving mitochondrial function via promoting Arl2 mRNA translation PMID 40892098
Measuring macular pigment optical density in vivo a review of techniques PMID 21221629
Lactandrate a D
3,6
Discovery of an Inhibitor of the Proteasome Subunit Rpn11 PMID 28191850
TNFRSF11B
Isovitexin 2′′
3,3'
Tioconazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses PMID 3510114
DC
MRS2603 860623
NADPH tetracyclohexanamine 100929
A rapid imaging
Succinate exacerbates mastitis in mice via extracellular vesicles derived from the gut microbiota a potential new mechanism for mastitis PMID 39543623
Tos
Detoxin C1 74717
A comprehensive insight on the recent development of Cyclic Dependent Kinase inhibitors as anticancer agents PMID 32707525
STING activator c
Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities PMID 32727735
PKA
proMMP
AXL 蛋白, Human (Biotinylated, HEK293, Fc)
2’
Nonprenylated Xanthones from Gentiana lutea, Frasera caroliniensis, and Centaurium erythraea as Novel Inhibitors of Vascular Smooth Muscle Cell Proliferation PMID 26580586
Removal of human ether
Proapoptotic role of CDK1 in overcoming paclitaxel resistance in ovarian cancer cells in response to combined treatment with paclitaxel and duloxetine PMID 39702300
Dihydrozeatin riboside
Salt
Vanillin restrains proliferation of triple negative breast cancer cells by inducing ferroptosis via mediating the KLF2/GPX4 axis PMID 40741604
H
Synthesis and in vivo evaluation of [(18)F]2
Cyanine7 DBCO 2692677
Ejiao ameliorates lipopolysaccharide
1,3
Ncf4
Syngap1
ADSL
Cadherin
Promoting epithelial
Cucurbitane glycosides from the fruits of Siraitia gros venorii and their inhibitory effects on Epstein
GPR120 Agonist 3 (Standard)
The antimicrobial and bioactive properties of lactobionic acid PMID 35174887
Hemerocallal A 659747
Tibric acid 37087
PQ
Discovery and Structural Optimization of Acridones as Broad
Cortisol Sensitizes Cochlear Hair Cells to Gentamicin Ototoxicity Via Endogenous Apoptotic Pathway PMID 38085767
Spike
NOX4 exacerbates Parkinson's disease pathology by promoting neuronal ferroptosis and neuroinflammation PMID 38993139
6β
AMPA receptor antagonist
冠毛素 1(PAPPA)基因
Tactical Approaches to Interconverting GPCR Agonists and Antagonists PMID 26390077
Epimedonin G
A small
Control of PHAS
Bin1
Epimedonin K
Development of Potent, Selective Surrogate WNT Molecules and Their Application in Defining Frizzled Requirements PMID 32220333
(3R)
NLRP6 exerts a protective role via NF
Prominent production of IL
N
PI3K
GSK3326595 (Standard)
alpha Tubulin 抗体 (YA625)(alpha Tubulin Antibody (YA625))
SEN 177
Multiple toxic effects of tetraconazole in Allium cepa L. meristematic cells PMID 33169279
Selective in vivo binding of [3H]naltriben to delta
Perindopril impurity 1 (Standard)
Ethylene Glycol
Naphthalene
Marsdenia tenacissima Extract Induces Autophagy and Apoptosis of Hepatocellular Cells via MIF/mToR Signaling PMID 35280512
p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid PMID 24969879
Deoxystreptamine kanosaminide
Cl
Mycoplasma pneumoniae
Diplacone 73676
Cellulase 9012
Lysophosphatidylcholine 14 0 Alleviates Lipopolysaccharide
Gut microbiota
BRD4 Inhibitor
Cabozantinib impurity 7 (Standard)
Sacubitrilat impurity 34
[Direct resolution of calcium folinate stereoisomers using a bovine serum albumin chiral HPLC column] PMID 14966932
Antihyperglycemic and antioxidative effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in mice fed with a high fat diet PMID 22489179
STING promotes ferroptosis through NCOA4
Tspan1 Mouse Pre
Vasoactive intestinal peptide shortens both G1 and S phases of neural cell cycle in whole postimplantation cultured mouse embryos PMID 9751145
L
Characterization of the antagonist actions of 5
SIRT6 inhibition delays peripheral nerve recovery by suppressing migration, phagocytosis and M2
rel
AMH
(R)
C
Puqiedinone, a novel 5 alpha
[Studies on the chemical constituents of Lonicera macranthoides] PMID 18973010
N,N
Raspberry ketone alleviates radiation
CBLC100
Anti
Temporin B 188713
BCA 蛋白浓度测定试剂盒 (BCA Protein Assay Kit)
Nurr1/RXR agonist 1
(±)
Itepekimab
PanK1调节剂、基因
(4R,5S)
H
Desisopropyle
Methyl propionate
角蛋白 4(KRT4)基因
2
BACH1 抗体 (YA4463)(BACH1 Antibody (YA4463))
Metadoxine, an ion
MCE
MCE
2,6
Imipramine counteracts corticosterone
CSH2
(3S,5S)
Megf6
MicroRNA
CFL1 restores the migratory capacity of bone marrow mesenchymal stem cells in primary Sjögren's syndrome by regulating CCR1 expression PMID 38183912
L
Hydrosorbaldehyde
Flow cytometric measurement of cytoplasmic free calcium in human peripheral blood T lymphocytes with fluo
3
2
HELQ suppresses migration and proliferation of non
Fleroxacin
Discovery of a Novel Chemical Class of mGlu(5) Allosteric Ligands with Distinct Modes of Pharmacology PMID 20981342
Oridonin inhibits aberrant AKT activation in breast cancer PMID 29844859
4,4
Ost4 Rat Pre
A Vip3Af mutant confers high resistance to broad lepidopteran insect pests PMID 39300681
Thalicminine 16408
IU2
Bst2 Mouse Pre
beta III Tubulin 抗体 (YA586)(beta III Tubulin Antibody (YA586))
WLS
Kel
Adsl
Klk10
High
Dusp8
Design and Evolution of a Macrocyclic Peptide Inhibitor of the Sonic Hedgehog/Patched Interaction PMID 28759213
CRBN ligand
Flexibility of GroES mobile loop is required for efficient chaperonin function PMID 22634549
Mef2d Mouse Pre
Itm2b
Chemogenetic inactivation reveals the inhibitory control function of the prefronto
Donanemab (LY3002813) dose
ATL
Antitumor activity of the Hsp90 inhibitor IPI
β2AR agonist 5
Prilocaine impurity 1 (Standard)
Boc
华烛之典提取物 (Hechtia glomerata Zucc.)
146310
Irf8
Design, synthesis and activity screening of cedrol derivatives as small molecule JAK3 inhibitors PMID 39222556
Design and optimization of a series of 4
Discovery of diarylheptanoids that activate α7 nAchR
Active
MCE
MCE
MCE
Z
NF
适配器相关蛋白复合物 3 亚基 beta 2(AP3B2)基因
APC/C
trans
Plumericin
Suc
Ventral subiculum promotes wakefulness through several pathways in male mice PMID 38734818
ST1060 1402702
Piperazine
L
Identification of potent orally active factor Xa inhibitors based on conjugation strategy and application of predictable fragment recommender system PMID 25523211
Rac1
Role of TGM2 in T‑cell lymphoblastic lymphoma via regulation of IL‑6/JAK/STAT3 signalling PMID 35014680
Construction of gastric cancer patient
MAO
Desmethyl Levofloxacin 117707
BOC
An improved method for cytogenetic analysis of meiotic aneuploidy in rodent and frog spermatocytes PMID 2259366
Adenocarcinoma of the pancreas in azaserine
Tiludronate bone pharmacology and safety PMID 8573421
Pectate Lyase, Aspergillus sp.
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid
hsa
Guraxetan
Imifoplatin (PT
Onilcamotide (RV001)
Pum2
NAPRT
Terephthalaldehyde 623
Irisin reverses high
CLDN3
Probing the spatiotemporal patterns of HBV multiplication reveals novel features of its subcellular processes PMID 34370796
Spirocyclic compound
GSKIP Human Pre
Pratensein 2284
3’
Swainsonine represses glioma cell proliferation, migration and invasion by reduction of miR
Cycloheximide impairs and enhances memory depending on dose and footshock intensity PMID 22610049
Discovery of a novel small molecule agonist scaffold for the APJ receptor PMID 27369451
hsa
Picenadol PMID 2986931
C4a Rat Pre
MCE
SCG3
DBCO
N1,N11
MCE
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