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Propargyl
Jolkinolide A 37905
Muc16
Ubd
[Effects of nizofenone on the action potential of guinea
Men1
6,8
Pharmacokinetics of tulathromycin in healthy and neutropenic mice challenged intranasally with lipopolysaccharide from Escherichia coli PMID 22585224
Antitussive, expectorant and anti
Neonatal treatment with cyclosporine A restores neurogenesis and spinogenesis in the Ts65Dn model of Down syndrome PMID 31085229
The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells PMID 9405464
Maml2
Micacocidin A, B and C, novel antimycoplasma agents from Pseudomonas sp. II. Structure elucidation PMID 9589069
PEGylation enhances the antibacterial and therapeutic potential of amphibian host defence peptides PMID 34656552
Bcl
Comparative evaluation of sensititre YeastOne and VITEK2 antifungal susceptibility tests with CLSI broth microdilution method of clinical Cryptococcus isolates in Taiwan PMID 39699241
Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs PMID 10871376
Z
(S)
Development of the First Small
MIB E3 泛素蛋白连接酶 1(MIB1)基因
A selective inhibitor of drp1, mdivi
Structure
NADP sodium hydrate 698999
Simultaneous determination of parecoxib and its main metabolites valdecoxib and hydroxylated valdecoxib in mouse plasma with a sensitive LC
调节因子 X5(RFX5)基因
Bispecific Aptamer
MiR
Effect of gluten exorphins A5 and B5 on the postprandial plasma insulin level in conscious rats PMID 7637543
Discovery of MKP10241, a Novel Small Molecule Targeting the GPR119/Incretin Axis to Treat Metabolic Disorders PMID 41054342
A new thiazolidinedione, NC
UNC1021
Caffeic acid attenuates irradiation
Inhibition of interleukin
IKAROS 家族锌指 2(IKZF2)基因
Discovery of Inhibitors of Aurora/PLK Targets as Anticancer Agents PMID 31381325
Methyleugenol alleviates pulmonary vascular remodeling in rats with high
Conversion of angiotensin I to angiotensin II PMID 190881
Anti
Nanozyme
ABT
Combined inhibition of EGFR and FGFRs with Cetuximab and Infigratinib showed effectiveness and relevance in proliferation and migration of HNSCC cell lines PMID 40449758
Milacemide, a glycine pro
Lead Optimization to Advance Protease
The selective dopamine D1 receptor antagonist, SCH23390, is a potent and high efficacy agonist at cloned human serotonin2C receptors PMID 11465634
Rbbp7
Marine polyunsaturated fatty acids and cancer therapy PMID 23299528
Studies on the toxicity of hexachlorophene in the rat PMID 4696307
CRBN ligand
Design, synthesis and anti
Idh3g
The discovery of 2,5
Phenylbutyl isoselenocyanate 1072807
Bacosine 198014
Transferrin 蛋白, Mouse (HEK293, His)
Steviolmonoside 60129
Discovery of DS79182026 A potent orally active hepcidin production inhibitor PMID 28705644
Cryptochrome 1 promotes osteogenic differentiation of human osteoblastic cells via Wnt/β
In vivo evidence for tachykininergic transmission using a new NK
Global metabolic inhibitors of sialyl
Novel thiazolopyridine derivatives of diflapolin as dual sEH/FLAP inhibitors with improved solubility PMID 37418786
Systematic analysis of human protein complexes identifies chromosome segregation proteins PMID 20360068
MCE
The discovery of non
SPI1
Phospholipase A2 of Peroxiredoxin 6 Plays a Critical Role in Cerebral Ischemia/Reperfusion Inflammatory Injury PMID 28424593
Assessing the Multitarget Therapeutic Potential of Novel 9
Terminal deoxynucleotidyl transferase indiscriminately incorporates ribonucleotides and deoxyribonucleotides PMID 11406636
Targeting the SHOC2
白细胞介素 18 结合蛋白(IL18BP)基因
Cdc20
MCE
Furowanin A
Methylated eicosapentaenoic acid and tetradecylthioacetic acid effects on fatty acid metabolism PMID 10484071
Soluble epoxide hydrolase and TRPC3 channels jointly contribute to homocysteine
Rfc1
Small molecules disaggregate alpha
(R)
A pathogenic role for IL
MiR
Anisperimus 170368
MJBIA9836 3057446
含微管相关的单加氧酶、钙调蛋白和 LIM 结构域 2(MICAL2)基因
Design, synthesis and biological evaluation of novel indolin
BH4 domain of antiapoptotic Bcl
MCE
[Discover potential inhibitors of 5
Efficacy and Synergy of Small Molecule Inhibitors Targeting FLT3
Discovery and early clinical evaluation of BMS
Impacts of Fertilization Regimes on Arbuscular Mycorrhizal Fungal (AMF) Community Composition Were Correlated with Organic Matter Composition in Maize Rhizosphere Soil PMID 27899920
MIF
Retaspimycin 857402
CRBN ligand
Compounds from Dryopteris fragrans (L.) Schott with cytotoxic activity PMID 24647035
S
Sparcl1
Imaging of Carbonic Anhydrase Level in Epilepsy with an Environment
Biphenylyl
双特异性磷酸酶 4(DUSP4)基因
羰基还原酶 1(CBR1)基因
Oral administration of adrafinil improves discrimination learning in aged beagle dogs PMID 10880682
MCE
FA 互补群 F(FANCF)基因
Grk2
Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy PMID 25104390
Glucagon receptor as a drug target A witches' brew of eye of newt (peptides) and toe of frog (receptors) PMID 28842950
Nascent transcript and single
Pyrazolo
(+)
Faf1
[HPLC analysis of nonsteroidal antirheumatic agents in biological materials. III. Pyrazolidinediones] PMID 9650370
Cardiac Safety of Ozanimod, a Novel Sphingosine
MCE
Chemistry and Biology of HPAs A Family of Ceramide Trafficking Inhibitors PMID 27628428
Polymer source affects in vitro
Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non
m
D
NK2R control of energy expenditure and feeding to treat metabolic diseases PMID 39537932
Ido1 Mouse Pre
Biosynthesis of quinolactacin A, a TNF production inhibitor PMID 17025018
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease PMID 17984323
α
IDO1
Proteinase
Ponceau S waste Ponceau S staining for total protein normalization PMID 30914243
EWS RNA 结合蛋白 1(EWSR1)基因
Systematic pharmacology and experimental validation revealed the mechanism of Bupleurum chinense DC
距花山姜提取物 (Alpinia calcarata Roscoe)
The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors PMID 26055709
MCE
The FGF/FGFR system in the microglial neuroinflammation with Borrelia burgdorferi likely intersectionality with other neurological conditions PMID 36650549
Functional analysis of leptin receptor activation using a Janus kinase/signal transducer and activator of transcription complementation assay PMID 14525952
p34cdc2 kinase activity is maintained upon activation of the replication checkpoint in Schizosaccharomyces pombe PMID 8710861
RAGE activation in macrophages and development of experimental diabetic polyneuropathy PMID 36477360
Comprehensive analysis of the effects of the traditional stir
细胞色素 P450 家族 1 亚家族 B 成员 1(CYP1B1)基因
The therapeutic potential of monoamine oxidase inhibitors PMID 16552415
Investigating the mechanism of Tongfeng Qingxiao Formula for improving gouty arthritis based on the neutrophil extracellular trapping network PMID 39736350
Inhibition of caspase
Dpp8
Dual topoisomerase IIα/EGFR
Surface Modification and Pore Size Regulation of MSN as Function Aflibercept Carrier for Anti
LKB1 controls inflammatory potential through CRTC2
Neuroprotective effect of paeoniflorin on okadaic acid
In silico identification of strong binders of the SARS
Computational study on the drug resistance mechanism of HCV NS3 protease to BMS
In vitro effect on group A streptococci of loracarbef versus cefadroxil, cefaclor and penicillin V PMID 8460347
Azumolene sodium 105336
MCE
Dopamine stabilizes tumor blood vessels by up
The Importance of Stereochemistry in 5
CpG oligodeoxynucleotides with double stem
Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity PMID 21245102
NOD1 Agonist Protects Against Lipopolysaccharide and D
Inhibition of CYP1B1 ameliorates cardiac hypertrophy induced by uremic toxin PMID 31746392
Loss of perinuclear theca ACTRT1 causes acrosome detachment and severe male subfertility in mice PMID 35616329
A rapid and sensitive LC
Effects of HR780, a novel 3
Keap1
TSLP 蛋白, Human (HEK293, His
Discovery of Novel PDEδ Degraders for the Treatment of KRAS Mutant Colorectal Cancer PMID 32603594
TD1092 intermediate
Molecular requirements involving the human platelet protease
Synthesis of Illudinine from Dimedone and Identification of Activity as a Monoamine Oxidase Inhibitor PMID 32830978
Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite PMID 31664127
The specific monocarboxylate transporter (MCT1) inhibitor, AR
Tizanidine
Loss
Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide PMID 18618712
In vivo and in vitro effect of 1,25
New beta
TDP1 Inhibitor
Imidazoleacetic acid
Combination of ataxia telangiectasia and Rad3
Further studies on the anti
Dietary Compound Kaempferol Inhibits Airway Thickening Induced by Allergic Reaction in a Bovine Serum Albumin
MCE
Lack of estrogenic or (anti
Kadsuphilin A 887770
带电多泡体蛋白 4A(CHMP4A)基因
Small Changes Make the Difference for SIRT2 Two Different Binding Modes for 3
Discovery of (R)
Octacosane 630
Activation of KCNQ2/3 potassium channels by novel pyrazolo[1,5
Homoharringtonine Combined with the Heat Shock Protein 90 Inhibitor IPI504 in the Treatment of FLT3
Alpha
Corticosteroidogenesis and adenosine 3', 5'
Cer1
Brevilin A Inhibits Prostate Cancer Progression by Decreasing PAX5
Apetalumoside B9
Mesothelin 蛋白, Mouse (HEK293, His)
Leo1
N2
In Silico Screening Identified Novel Small
Rhoc
SAR
CT
TRK
The thiosemicarbazone, DpC, broadly synergizes with multiple anti
Lack of antitumor effects
HCT
Low level of mancozeb exposure affects ovary in mice PMID 35617905
Sinapine suppresses ROS
(
Structure
Bacitracin Zinc 1405
PG
FOXO1(C
Investigation of Siderophore
Paracetamol potentiates the antidepressant
Pld4
甘丙肽和 GMAP 前肽原(GAL)基因
TL1A is a TNF
Production of monoclonal and polyclonal antibodies against human osteocalcin sequences and development of a two
Crystal structure of the sugar acid
ATP treatment of human monocytes promotes caspase
A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents PMID 20880401
Melatonin regulates proliferation and apoptosis of endometrial stromal cells via MT1 PMID 34343226
ARV471
Desmethyl cyclobenzaprine hydrochloride 438
MCE
组织蛋白酶 L(CTSL)基因
CRBN ligand
Ketoprofen impurity 2 (Standard)
AMN082, a metabotropic glutamate receptor 7 allosteric agonist, attenuates locomotor sensitization and cross
SARS
Design, synthesis, and biological evaluation of novel FGFR1 PROTACs PMID 39756204
Synthesis and biological evaluation of pyrrole
MCE
Design, synthesis, and induction of tumor ferroptosis activity of a novel FSP1 protein degrading agent PMID 41172647
ASS1 activator 1
肌动蛋白丝切蛋白 1(CFL1)基因
AMPK activator 18
Potential inhibitors of S
AP1867
Small
Tau Derived Hexapeptide AcPHF6 Promotes Beta
Methylergometrine antagonizes 5 HT in the temporal artery PMID 3691600
Viral RNA Replication Suppression of SARS
hsa
The transport and metabolism of the uridine mononucleotides by rat jejunum in vitro PMID 2778724
Dihydroxanthene
CDK2 degrader 7 3030279
Phe
CRBN ligand
Expression of interleukin
Ginsenoside Rg1 Suppresses Pyroptosis via the NF
Ghitm
黄帚橐吾提取物 (Ligularia virgaurea (Maxim.) Mattf.)
Simultaneous determination of neonicotinoid insecticides in human serum and urine using diatomaceous earth
EMB
CRBN ligand
GLUT
Minecoside Modulates Cell Invasion via Regulation of CXCR4 Expression in Breast and Colon Cancer Cells PMID 32016931
MCE
Small
Flnc
Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis PMID 26616205
CRBN ligand
Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis PMID 28364121
Trichothecenes from simple to complex mycotoxins PMID 22069741
CD79B
4'
Synthesis and biological evaluation of clovamide analogues with catechol functionality as potent Parkinson's disease agents in vitro and in vivo PMID 30470490
Sgpp2
ZLY025
The gastrin
Phenyl urea based adjuvants for β
HA1/Hemagglutinin 蛋白, H1N1 (ACQ89903, HEK293, His)
Total Synthesis of the Antitumor Antibiotic Basidalin PMID 27347696
UTP25 小亚基加工组组件(UTP25)基因
molecular structure
Comparison of the anti
Cyclo (leucylglycine) inhibits the development of morphine induced analgesic tolerance and dopamine receptor supersensitivity in rats PMID 7190637
Targeting UBE2B
Preclinical Antitumor Efficacy of a Novel Anti
De novo development of proteolytically resistant therapeutic peptides for oral administration PMID 32393891
Inhibition of AXL and VEGF
DR3/TNFRSF25 蛋白, Cynomolgus (HEK293, Fc)
Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis PMID 35869501
Antcin K suppresses proinflammatory cytokines expression via the PI3K, Akt and NF
K ISS1 受体(Kiss1r)基因
Ifit1
Nfat5
Interferon
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node PMID 11517919
Acid violet 43 4430
Hace1
NIR
Characterization of the epithelial membrane protein 3 interaction network reveals a potential functional link to mitogenic signal transduction regulation PMID 30614533
Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety PMID 26360704
Y
Two new megastigmanes from Chinese traditional medicinal plant Sedum sarmentosum PMID 28152607
Prolactin
Determination of xylazine and its metabolites by GC
6
Pdha1
TCS 2510 346673
Hyperalgesic and hypoalgesic mechanisms evoked by the acute administration of CCL5 in mice PMID 28126501
Isoflavones from the seedpods of Tephrosia vogelii and pyrazoisopongaflavone with anti
Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H
The NK1 receptor antagonist aprepitant attenuates NK1 agonist
Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis
H3 relaxin demonstrates antifibrotic properties via the RXFP1 receptor PMID 21229994
Rspo1
Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model roles for wildtype p53 PMID 33941851
(R)
Lanabecestat Neuroimaging results in early symptomatic Alzheimer's disease PMID 33614894
无柄新乌檀提取物 (Neonauclea sessilifolia (Roxb.) Merr.)
Effects of natural RNA modifications on the activity of SARS
Tryptophan 2,3
Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation PMID 39536262
Comprehensive genetic characterization of CLL a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping PMID 17805327
AFM
Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists PMID 8389876
EMB Human Pre
Acid violet 1 6441
Repurposing the amino
ABL1‒YAP1 axis in intestinal stem cell activated by deoxycholic acid contributes to hepatic steatosis PMID 39707364
Intraphagocytic killing of Salmonella typhimurium by liposome
Cfl1
Small
Antibody to human leukocyte antigen triggers endothelial exocytosis PMID 17229850
Panaxytriol Inhibits Lipopolysaccharide
线叶石韦提取物 (Pyrrosia linearifolia (Hook.) Ching)
bPiDI a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse PMID 21232049
Changes in cyclin dependent kinase expression and activity accompanying lens fiber cell differentiation PMID 10620399
FHND5032 3076057
The beta3
Cannabidiol Analogue CIAC001 for the Treatment of Morphine
Etf1
SNPB
EPHA5 蛋白, Mouse (HEK293, His)
细胞死亡诱导 DFFA 样效应子 c(CIDEC)基因
Discovery of a potent and selective agonist of the prostaglandin EP4 receptor PMID 12643927
Discovery and Hit to Lead Optimization of Macrocyclic Peptides as Novel Tropomyosin Receptor Kinase A Antagonists PMID 38950284
Strain
Methyl 9
Activation of eNOS by D
Bioactivation of 5
In vitro and in vivo hypoglycemia effect of oxyberberine, a novel HO
Vps35
Haloquinone Chloroimides as Toxic Disinfection Byproducts Identified in Drinking Water PMID 34881563
Z
Dye Reagents 抑制剂
Calpain inhibition protects against virus
5'
Stimulation of growth hormone by kisspeptin antagonists in ewes PMID 29549187
4
In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP
DNA binding properties of key sandramycin analogues systematic examination of the intercalation chromophore PMID 10218823
4
Generation of a floxed allele of Smad5 for cre
A role for WNT proteins in induction of dermomyotome PMID 9356179
Molecular inhibition of prostaglandin E2 with GW627368X Therapeutic potential and preclinical safety assessment in mouse sarcoma model PMID 25894216
TRC160334 sodium 1293290
Colec12
酸性核磷蛋白 32 家族成员 A(ANP32A)基因
10
Eepd1
Determination of itraconazole and hydroxyitraconazole in human serum and plasma by micellar electrokinetic chromatography PMID 14558612
HDAC1
The NLRP3
In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX
Sarco/Endoplasmic Reticulum Ca2+ Transporting ATPase (SERCA) Modulates Autophagic, Inflammatory, and Mitochondrial Responses during Influenza A Virus Infection in Human Lung Cells PMID 33692207
5
Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells PMID 28061441
AHR
Development of novel amino
Jinflexin A 2055155
Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques PMID 29467313
n
Synthesis and computational investigation of novel 2
Host
Rbm5
Strategies for the design of HIV
VDAC1 regulates mitophagy in NLRP3 inflammasome activation in retinal capillary endothelial cells under high
Hydroxysulochrin, a tea pollen growth inhibitor from the fungus Aureobasidium sp PMID 12729018
Functional differentiation in the mammalian metallothionein gene family metal binding features of mouse MT4 and comparison with its paralog MT1 PMID 15033980
Atp1a1
Insecticidal sesquiterpene polyol esters from Celastrus angulatus PMID 11738404
ZL0580 2377151
Neurite Outgrowth
Inappropriate Expression of an NLP Effector in Colletotrichum orbiculare Impairs Infection on Cucurbitaceae Cultivars via Plant Recognition of the C
MCE
Fluorine
Irf1
Pla2g2a
Long
An Anti
An amphipathic peptide targeting the gp41 cytoplasmic tail kills HIV
The immunomodulatory activity of tetra
A Photo
Mgst1
The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic patients PMID 24458358
Lancl2
Isolation, characterization, and hepatoprotective properties of betulinic acid and ricinine from Tetracarpidium conophorum seeds (Euphorbiaceae) PMID 32529649
Bacterial c
PZ703b
Fibroblast Growth Factor 21 Exerts its Anti
BVD 10 262418
Insights into diphthamide, key diphtheria toxin effector PMID 23645155
Pharmacological characterization of a novel nonpeptide antagonist of the human gonadotropin
突触体相关蛋白 23(SNAP23)基因
Recombinant cobra venom factor PMID 15159065
Map1lc3a
mmu
PROTAC pan
Il12rb2
Synthesis of an O
Oleanolic acid enhanced the anticancer effect of fluorouracil by regulating Ca2+ levels in hepatocellular carcinoma cells PMID 40243820
Discovery of Novel Apigenin
Modeling Gene Expression Lac operon PMID 34891476
MI
Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID
Novel PIKK inhibitor antibody
MCE
MCE
(Arg)9,TAMRA
5
Inhibition of oxytocin receptor function by direct binding of progesterone PMID 9548257
Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease PMID 30249354
Mps1 controls spindle assembly, SAC, and DNA repair in the first cleavage of mouse early embryos PMID 33025669
Ak2
Synthesis of β
IDO1
Gsdmd
Caffeic acid exhibits anti
Ontazolast 147432
Therapy of empagliflozin plus metformin on T2DM mice shows no higher amelioration for glucose and lipid metabolism than empagliflozin monotherapy PMID 31271767
Role of dopamine D(4) receptors in motor hyperactivity induced by neonatal 6
AcGlcAs A Novel P53
Influence of the Carboxylic Function on the Degradation of d
IDO
Antiviral flavonoids from the root bark of Morus alba L PMID 12648543
Metabolic Disease 抑制剂
Targeting Fibroblast Activation Protein for Molecular Imaging of Fibrotic Remodeling in Pulmonary Arterial Hypertension PMID 39753365
Binding of amine
Design, synthesis, and evaluation of novel stilbene derivatives that degrade acidic nucleoplasmic DNA
PEGylated lipid screening, composition optimization, and structure
Polysaccharide deacetylases serve as new targets for the design of inhibitors against Bacillus anthracis and Bacillus cereus PMID 29983281
PRKCH
AC260584 (4
Two validated liquid chromatography
MS
W2
An Assessment of Physical and N6
Four Isosteroidal Alkaloids from Fritillaria Alleviate Lipopolysaccharide
152940
Activation of nicotinamide phosphoribosyltransferase protects against unilateral renal ischemia
Tyramine antagonistic properties of AGN 1135, an irreversible inhibitor of monoamine oxidase type B PMID 6793119
USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP PMID 36470870
d
Studies on the mechanism of interaction between rabbit transferrin and reticulocytes PMID 4104163
AI
Chronic toxic effects of chloroxylenol exposure on Rana chensinensis Insights from endochondral ossfication PMID 39489103
Influence of Cedar Essential Oil on Physical and Biological Properties of Hemostatic, Antibacterial, and Antioxidant Polyvinyl Alcohol/Cedar Oil/Kaolin Composite Hydrogels PMID 36559143
BSPOTPE 2046513
Thiophanat
Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6 PMID 20045404
Incorporation of sodium channel blocking and free radical scavenging activities into a single drug, AM
Discovery and computer aided potency optimization of a novel class of small molecule CXCR4 antagonists PMID 24205302
Coronene
Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N
Small
Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)
Generation of Clickable Pittsburgh Compound B for the Detection and Capture of β
Structure
The mechanism of action of phenylalanine ammonia
Fgf3
On the reaction specificity of the lipoxygenase from tomato fruits PMID 7905748
Small
TRPA1 agonist
Discovery of potent and orally bioavailable indazole
Tspo
In vitro and in vivo antibacterial activities of carumonam (AMA
PNU 101099
Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110) PMID 21806599
Enzymatic Biotransformation of Gypenoside XLIX into Gylongiposide I and Their Antiviral Roles against Enterovirus 71 In Vitro PMID 35807341
Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective, and Orally Available Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist PMID 32022560
L
BI
Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channel PMID 20304642
Small molecule inhibitor of type three secretion suppresses acute and chronic Chlamydia trachomatis infection in a novel urogenital Chlamydia model PMID 25695086
The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles PMID 20635194
Discovery of IACS
Fxyd7
A new antihypertensive metolazone treatment of hypertension PMID 881576
Inhibition of AMPA receptor
Pivmecillinam in the treatment of urinary tract infections PMID 10969050
Qrsl1
GBP3
MS1
Obesity
2,2
3,5
Als2
MCE
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