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The whereabouts of a morphogen direct evidence for short
SBI
Discovery of a novel napabucasin derivative B16 as a potent STAT3 inhibitor for the treatment of triple
Targeting RRM2 with dual
Chemical and biophysical characterization of novel potassium channel blocker 3
Efnb3
CRBN ligand
Slc8b1
Studies on the luteolytic activity of MDL
Pharmacology of SCH00013 a novel Ca2+ sensitizer PMID 11830752
Late phase bronchoconstriction and eosinophilia as well as methacholine hyperresponsiveness in Ascaris
Synthesis of 6
Evariquinone
SB
Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK
Aroylguanidine
4
Inhibition of ovulation in the perfused rat ovary by the synthetic collagenase inhibitor SC 44463 PMID 1714777
NPY Y2 receptor agonist PYY(3
Design, synthesis and evaluation of novel 5
Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation PMID 27049577
细胞周期蛋白G相关激酶（Gak）基因
Olsutamig 3034664
Cell
Cbl
IAP antagonists induce autoubiquitination of c
Netzahualcoyonol from Salacia multiflora (Lam.) DC. (Celastraceae) roots as a bioactive compound against gram
tumor cell metabolism
Moderate enhancement of the promotion phase of skin tumorigenesis in hairless mice by topical pretreatment with a mitosis
Synthesis and pharmacological evaluation of novel nitrobenzenic thromboxane modulators as antiplatelet agents acting on both the alpha and beta isoforms of the human thromboxane receptor PMID 16759113
Geranylgeranyl Pyrophosphate Promotes Profibrotic Factors and Collagen
Preclinical antitumor activity of BMS
ONO
Phosphorylation of CRTC3 by the salt
Arachidonoyl m
Discovery of M3 Antagonist
溶质载体家族 51 亚基β（SLC51B）基因
The programmed death
NADH：泛醌氧化还原酶亚基 A2（NDUFA2）基因
C
The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells PMID 21743064
Sox1
Proteinase
Basic principles of cancer cell culture PMID 14634214
Cyren
Pharmacodynamic characterization of rytvela, a novel allosteric anti
Synthesis and immunostimulating properties of novel adamant
Upp2
Possible inhibitory mechanism of FK506 (tacrolimus hydrate) ointment for atopic dermatitis based on animal models PMID 10497905
Discovery of novel quinazoline
The ABI4
非典型趋化因子受体 3（Ackr3）基因
T
Quercetin alleviates neonatal hypoxic
Electron microscopic aspects of the effects of certain prostaglandin analogs on mouse testes PMID 26429171
Cardiac
TL1A A New Potential Target in the Treatment of Inflammatory Bowel Disease PMID 33475057
Imperatoxin A, a Cell
Clinical pharmacokinetics of epirubicin PMID 8070217
Ubr5
Cyclo(Tyr
MCE
hsa
Terpenoids and Meroterpenoids from Cultures of Two Grass
Synthesis and evaluation of (E)
N6
PI5P4Kγ降解剂、基因
立即早期反应 5 样（IER5L）基因
Ang
MUC1
ERRα antagonist
Hace1
(S)
[Exometabolites of the Fungal Isolates (Genus Penicillium, Section Chrysogena) from Low
CRBN ligand
Lunularin 37116
Multivalent assembly of nucleolin
Abscisic Acid Mediates Salicylic Acid Induced Chilling Tolerance of Grafted Cucumber by Activating H2O2 Biosynthesis and Accumulation PMID 36555697
Polycyclic Polyprenylated Acylphloroglucinols Bearing a Lavandulyl
Mechanism of memantine block of NMDA
Azithromycin
MCE
5F
BMS 180742 138828
A yeast
Ppa1
Esam
Pubertal low dose exposure to benzophenone
EP4 receptor antagonist 7 3035217
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α
Evaluation of molecules based on the electron donor
Three
Peptide YY derivatives as selective neuropeptide Y/peptide YY Y1 and Y2 agonists devoided of activity for the Y3 receptor sub
Acute effects of bisoprolol on respiratory sinus arrhythmia PMID 9711469
Population pharmacokinetic/pharmacodynamic modeling of drug
Go/z
Methylphenylethyne 673
SC
From High
4
ADAMTS1
Dimorpholamine (1064 Th)
CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer PMID 18224687
Niaprazine in the treatment of autistic disorder PMID 10456769
Plumericin 77
ADAL1
MCE
Effects of adrenomedullin and calcitonin gene
Prostaglandin D2
Development of a multigram synthesis of the bradykinin receptor 2 agonist FR
7
Afamin
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation PMID 25622091
CRBN ligand
Presenilin
Tridecane
LASSBio
Gallamine 153
Doxylamine 469
Seclidemstat mesylate 2044953
Rab11b
MCE
Alterations in macrophage phagocytosis and inflammatory tone following exposure to the organochlorine compounds oxychlordane and trans
GS
Comparison of the chemotherapeutic and pharmacodynamic activities of cephradine, cephalothin, and cephaloridine in mice PMID 4790592
Antitumor activity of jujuboside B and the underlying mechanism via induction of apoptosis and autophagy PMID 24547878
Biotin as a probe of the surface of Ascaris suum developmental stages PMID 2385267
2,4,6
Functional characterization of mouse cation transporter mOCT2 compared with mOCT1 PMID 12176030
Lasiocarpine 303
Behavioral effects of the dopamine autoreceptor agonist PD 128483 alone and in combination with cocaine PMID 7932152
Eif4ebp1
MCE
Efficacy of intracoronary versus intravenous FGF
FLII
LAH
Molecular mechanism of 2
SP8
Determination of the GABAergic antidepressant drug fengabine and some of its metabolites in plasma by capillary gas chromatography with electron
Dual depletion of myeloid
Ube2i Mouse Pre
Discovery of KRAS
6
Dimecrotic acid 7706
Gallium compound GaQ(3)
pDC depletion induced by CD317 blockade drives the antitumor immune response in head and neck squamous cell carcinoma PMID 31422204
A new class of orally active glycol renin inhibitors containing phenyllactic acid at P3 PMID 2496685
Sirtuin modulator 2
Thromboxane A2 inhibition therapeutic potential in bronchial asthma PMID 14720071
SPA107 179939
NLRP3 Mediates NOXs
14
Laminins in tumor
Treatment of warty dyskeratoma with tazarotenic acid PMID 11807455
A kinetic study and application of a novel carbonyl reductase isolated from Rhodococcus erythropolis PMID 8000863
A novel catecholamine, arbutamine, for a pharmacological cardiac stress agent PMID 8723168
[Des
A synthetic small molecule stalls pre
Hexachlorophene inhibits Wnt/beta
Radiomodulatory effect of a non
Pyrene excimer signaling molecular beacons for probing nucleic acids PMID 18078339
D
CRBN ligand
Discovery of berberine based derivatives as anti
Acid violet 54
Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors Synthesis and Structure
DNA hypomethylation of Syk induces oxidative stress and apoptosis via the PKCβ/P66shc signaling pathway in diabetic kidney disease PMID 38522019
白三烯 B4 受体 1（Ltb4r1）基因
His
Arogenate dehydratase 76600
Metabolism of n
Discovery of INCB3344, a potent, selective and orally bioavailable antagonist of human and murine CCR2 PMID 21036044
A Non
Structural recognition of a novel fibrinogen gamma chain sequence (117
Hippodemia convergens
MBD1 抗体 (YA6650)（MBD1 Antibody (YA6650)）
PF
Anastrozole impurity 1
Ftsj3
过氧化物酶体生物合成因子 26（PEX26）基因
D
MCE
MCE
MCE
The Activation of Muscarinic Acetylcholine Receptors Protects against Neuroinflammation in a Mouse Model through Attenuating Microglial Inflammation PMID 39408758
501A054
allelopathic activity
CASP3 activator 1
LZL50
AC
AB054
载脂蛋白 A4（APOA4）基因
Rhein 1
8
Casticin 479
ATP 合酶膜亚基 g（ATP5MG）基因
SCR
激素上调的 Neu 相关激酶（HUNK）基因
Nectin
Hhat
MicroRNA
mmu
Tes and HEPES buffers in mammalian cell cultures and viral studies problem of carbon dioxide requirement PMID 4361424
Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H
Structural basis of neuropeptide Y signaling through Y1 receptor PMID 35165283
Short IL
Mancozeb, a fungicide routinely used in agriculture, worsens nonalcoholic fatty liver disease in the human HepG2 cell model PMID 27016407
Mcub
Cited2
Pmaip1
Discovery and Characterization of BAY
Dpt
Naringenin modulates the NO‑cGMP‑PKG signaling pathway by binding to AKT to enhance osteogenic differentiation in hPDLSCs PMID 38940332
Use of fluorine
Signaling through CD70 regulates B cell activation and IgG production PMID 15356138
Impact of Six Typical Processing Methods on the Chemical Composition of Tea Leaves Using a Single Camellia sinensis Cultivar, Longjing 43 PMID 30403138
ML202
Gh1
3’
Etv5
The effect of ziprasidone on body weight and energy expenditure in female rats PMID 22209671
Synthesis and in vitro biological evaluation of 2,6,9
Eef1a1
非典型趋化因子受体 3（Ackr3）基因
PE
Effect of prenatal allylestrenol treatment (hormonal imprinting) on the serum testosterone and progesterone level in adult rats PMID 7590089
Bacterial oxidation of 2
DeSUMOylating isopeptidase 1 participates in the faithful chromosome segregation and vincristine sensitivity PMID 39698932
Others 抑制剂
Dnp
5
6′
QSAR models for HEPT derivates as NNRTI inhibitors based on Monte Carlo method PMID 24657566
Cyclooxygenase
Flovagatran (TGN 255)
MME 蛋白, Human (HEK293, N
Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways PMID 30209783
Nanoscale Peptide Self
Advanced oxidation protein products accelerates paracetamol
Unrevealing the shared genetic mechanisms underlying C
PPARγ inhibitors enhance the efficacy of statin therapy for steroid
MCE
mmu
Gut Microbiota
Pifithrin
Domperidone, a new dopamine antagonist PMID 3527396
Uhrf2
葡糖胺基 (N
Deflazacort
Upf1
TMX
m6A RNA hypermethylation
Pharmacokinetics of cefovecin sodium after subcutaneous administration to Hermann's tortoises (Testudo hermanni) PMID 25255182
Lct
Blockade of lysosomal acid ceramidase induces GluN2B
Uroguanylin
The effect of glutaurine on thyroid hormones in the rat PMID 3561723
Evaluating the ligand specificity of zebrafish parathyroid hormone (PTH) receptors comparison of PTH, PTH
Lacc1
Suppressive effects of isorhynchophylline on 5
N
7
Methyl salicylate is a critical mobile signal for plant systemic acquired resistance PMID 17916738
Steap2
Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2
Histamine H3
Cbz
联系方式 1（CNTN1）基因
Effects of three diterpenoids on tumour cell proliferation and telomerase activity PMID 19521915
Structure
SCGN deficiency is a risk factor for autism spectrum disorder PMID 36588101
TGFBR2/TGF
Phenoxymethylpenicillin (penicillin V) and phenethicillin PMID 4990453
Rhodojaponin VI ameliorates podocyte injury related with MDM2/Notch1 pathway in rat experimental membranous nephropathy PMID 39011853
P2Y12 receptor modulation of ADP
Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS
Design, Synthesis, and Biological Evaluation of Novel Selenium (Se
Benadrostin, new inhibitor of poly(ADP
Neurofibromatosis 1
Percutaneous Delivery of Hederacoside C
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders PMID 39406745
AM
RNASE3
核糖体蛋白 S6 激酶 A2（Rps6ka2）基因
Ascl4
DBCO
Laser photolysis of caged calcium rates of calcium release by nitrophenyl
Design, Synthesis, and Biological Evaluation of New Improved Ferrostatin
Design, Synthesis, and Biological Evaluation of Novel, Non
Arvenin I 65247
Aurora A 抗体 (YA827)（Aurora A Antibody (YA827)）
Fatostatin 125256
Inhibition by (D
Kel Mouse Pre
BMS 488043 452296
Identification of a 4
Sumo1
hsa
LHVS 170111
Dipotassium tetrachloroplatinate 10025
艾代拉里斯
PBF509, an Adenosine A2A Receptor Antagonist With Efficacy in Rodent Models of Movement Disorders PMID 30405415
WAY 123783
3'
1,3
Lenampicillin hydrochloride 80734
嵌入（EMB）基因
Rational design of an auxin antagonist of the SCF(TIR1) auxin receptor complex PMID 22234040
6
AAPDARETA
Gala
PanK3调节剂、基因
ABX196
Optical control of TRPV1 channels PMID 23873837
DUSP8 Human Pre
CRBN ligand
Selective membrane disruption by the cyclotide kalata B7 complex ions and essential functional groups in the phosphatidylethanolamine binding pocket PMID 26878982
A novel selective peroxisome proliferator
KRAS G12C inhibitor 62 2658588
MCE
An Inhibitory Effect of Dryocrassin ABBA on Staphylococcus aureus vWbp That Protects Mice From Pneumonia PMID 30728809
N
Discovery of 4
ROS Kinase
Lincomycin 2
A novel hydroxytyrosol derivative HT
All
Ligand binding inhibitors of A1 adenosine receptor from Rana rugosa are phospholipase A2s PMID 10691971
Assessing the developing pharmacotherapeutic landscape in hepatitis B treatment a spotlight on drugs in phase II clinical trials PMID 35511483
Lycium barbarum Glycopeptide Alleviates Neomycin
2,2
Daporinad 658084
Adenosine A1 receptor agonist, N6
[Advances in Molecular Cloning] PMID 27028806
Bassianin 54278
K(ATP) channel opener diazoxide prevents neurodegeneration a new mechanism of action via antioxidative pathway activation PMID 24040400
Injectable thermosensitive hydrogel co
Tyrosine ethyl ester
Etfa
WIN
CA1001
Fenpyrazamine (胺苯吡菌酮)
Pralidoxime for organophosphate poisoning PMID 17174692
IgG1 蛋白, Human (D239E, L241E, HEK293)
LMAN2 蛋白, Human (HEK293, His)
Anamorelin hydrochloride 861998
Magea4
Spon1+ inflammatory monocytes promote collagen remodeling and lung cancer metastasis through lipoprotein receptor 8 signaling PMID 38716730
Applications of self
Structure
Stabilization of HIF
Synthesis and pharmacological evaluation of 1H
n
Synthesis and SAR of C12
Midbrain glutamatergic circuit mechanism of resilience to socially transferred allodynia in male mice PMID 38858350
A selective antagonist reveals a potential role of G protein
A tetrapeptide isolated from hamster embryo with central opiate properties on gastrointestinal motility but not on pain perception PMID 3014251
Naphthalene Diimide
Cholesterylation of Smoothened is a calcium
The study of a novel CDK8 inhibitor E966
Loxapine 1977
Complex I inhibition combined with TLR activation in the breast tumor microenvironment educates cytotoxic neutrophils PMID 40644540
Substrate
MEK4 inhibitor
NAADP receptor modulator
Ptprk
Shrimp Plasma MANF Works as an Invertebrate Anti
Protective effect and mechanism of Saikosaponin A against oxidative damage in cochlear hair cells in vitro PMID 41017590
Neuropilin
SAMD12 as a Master Regulator of MAP4Ks by Decoupling Kinases From the CNKSR2 Scaffold PMID 40010432
MCE
KIF3A inhibits nasopharyngeal carcinoma proliferation, migration and invasion by interacting with β
肌细胞增强因子 2D（MEF2D）基因
(3S,5S)
Synthesis and biological evaluation of 14
Inflammatory cells and chemokines sustain FGF2
Description of the constitutive activity of cloned human melatonin receptors hMT(1) and hMT(2) and discovery of inverse agonists PMID 22017484
Oprm1
CD44 蛋白, Human (242a.a, HEK293, hFc)
PKC412 normalizes mutation
Regulation of microglia polarization via mannose receptor
Galanin receptor subtypes PMID 10689365
Brca1
Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer PMID 26095253
MCE
Ube2k
DMT
Ttc7b
Pharmacologic profile of the selective mitochondrial
The design and synthesis of selective and potent selenium
KRH
L
Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site PMID 26961873
Abi1
pyrosequencing
Discovery of Non
The optical resolution of racemic chlorpheniramine and its stereoselective pharmacokinetics in rat plasma PMID 1350627
Cbs
Lmo4
Inhibition by alpha 2
核糖体蛋白 L36a（RPL36A）基因
MCE
Cbz
10
WX
MCE
Fast segmentation and multiplexing imaging of organelles in live cells PMID 40118840
TIMP
Plp2
Crebanine induces ROS
Molecular properties of apelin tissue distribution and receptor binding PMID 11336787
NHPI
AMH
Antiobesity effect of MK
HSF1/AMPK activator 1
Dictamnine alleviates DSS
JTV
HIF
MCE
LIX/CXCL5 蛋白, Mouse
Pantoprazole sulfide 102625
TPD52 样 1（TPD52L1）基因
Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells PMID 21832043
Kinesin
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator
MCE
Chitinase
Bithionol (sulfoxide) 844
Design, synthesis, and discovery of novel trans
Dehydrodiisoeugenol 2680
8
hsa
TXNDC12 Human Pre
5
3,5
2
Boc
N
10
MCE
Ap5A 41708
Restricting the induction of NGF in ovarian stroma engenders selective follicular activation through the mTOR signaling pathway PMID 28542147
5
Z
L
Serial transcriptome analysis and cross
CDK8
Urofollitropin 97048
Selective and Marked Blockade of Endothelial Sprouting Behavior Using Paclitaxel and Related Pharmacologic Agents PMID 34563512
Gramicidin S 113
Vancomycin hydrochloride 1404
Upregulation of mitochondrial PGK1 by ROS
Cyperol
D
The S1P1 receptor
The three
4,5,6,7
Neuropilin
MCE
The biology and toxicology of molluscicides, Bayluscide PMID 6763710
Simultaneous Determination of Amphetamine
Notch signaling promotes osteoclast maturation and resorptive activity PMID 25914241
Evaluation of the Structure
RNF43 蛋白, Human (154a.a, HEK293, Fc)
zwitterion
Clozapine inhibits catalepsy induced by olanzapine and loxapine, but prolongs catalepsy induced by SCH 23390 in rats PMID 9089667
Timonacic 444
α
5
degradation tag
ATB
Isolation of chebulic acid from Terminalia chebula Retz. and its antioxidant effect in isolated rat hepatocytes PMID 16932919
Methyl diacetoxy
CRBN ligand
YM 44778
TOM1 抗体 (YA6807)（TOM1 Antibody (YA6807)）
ASK1
O
α,β
Successful Strategies for Mitigation of a Preclinical Signal for Phototoxicity in a DGAT1 Inhibitor PMID 31413796
CD40 蛋白, Rat (HEK293, Fc)
Spectinomycin inhibits the self
Thalidomide (THD) alleviates radiation induced lung fibrosis (RILF) via down
Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen PMID 37130331
ACTC1 Human Pre
Megf6 Mouse Pre
ML 202
Ferroptosis
CD40 蛋白, Mouse (Biotinylated , HEK293, His
Incensole Acetate 34701
STING Driving Synaptic Phagocytosis of Hippocampal Microglia/Macrophages Contributes to Cognitive Impairment in Sepsis
Protecting the brain from stroke Huoxue Rongluo formula (HXRLF) targets ferroptosis for neuroprotection PMID 40744419
Discovery of fibroblast growth factor 2
Triptolide promotes degradation of the unfolded gain
CARHSP1 蛋白, Human (His)
Acetylcarnitine Is a Candidate Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma PMID 26976432
R
Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas PMID 26174628
Cytidine
Long term use of lokivetmab (Cytopoint®) in atopic dogs PMID 40133889
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