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In vitro dermal penetration study of carbofuran, carbosulfan, and furathiocarb PMID 12734638
hsa
Delgocitinib 1263774
MAB21L2
Design, Synthesis, and In Vivo Evaluation of Isosteviol Derivatives as New SIRT3 Activators with Highly Potent Cardioprotective Effects PMID 38572607
ROS
CT179
MCE
Inhibitors of insulin
MTHFD2
A simple fluorescent method to determine complement
IMPDH
α
Inhibitory effect of the selective serotonin reuptake inhibitor paroxetine on human Kv1.3 channels PMID 34662565
Gpha2
Adam15
The inhibitory effect of gypenoside stereoisomers, gypenoside L and gypenoside LI, isolated from Gynostemma pentaphyllum on the growth of human lung cancer A549 cells PMID 29545210
Acridone
CXCL1 Human Pre
ALCAM
Evaluation of Antioxidant Activity of Picrorhiza kurroa (Leaves) Extracts PMID 24082348
Haliangicin B 661466
Small
The role and possible mechanism of the ferroptosis
S 59
5
CTR/AMYR activator
Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation PMID 26817948
The inhibition by 6
Metabolically stable
LY231617 141545
Betulinic acid derivatives NVX
Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin
Human gut M cells resemble dendritic cells and present gluten antigen PMID 41372409
IL
ERR
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress PMID 34747299
Azido
N
Azido
Nidulol
PF
Methyl diacetoxy
Different levels of autophagy induced by transient serum starvation regulate metabolism and differentiation of porcine skeletal muscle satellite cells PMID 37573414
CLRN3 Human Pre
Formononetin Defeats Multidrug
Matairesinol
Discovery of novel Bcr
polymeric micellar formulation
SUCLG1 Human Pre
Pitavastatin
Spcs3 Rat Pre
Injectable in situ forming kartogenin
Dextran
Quantification of 2
transplanted leeks
creatine biosynthesis
(1S,2R)
Near
PI4KIII beta inhibitor 3 1245319
Design and synthesis of β
睾丸表达 12（TEX12）基因
spalt 样转录因子 1（SALL1）基因
CI686
Oudenone 31323
CI
ROR
Suppression of p16 Induces mTORC1
细胞色素 c 氧化酶组装因子 6（COA6）基因
泛酸激酶 4 (无活性)（PANK4）基因
modulator
Neddylation signaling inactivation by tetracaine hydrochloride suppresses cell proliferation and alleviates vemurafenib
Functional analysis of the biomimetic silica precipitating activity of the R5 peptide from Cylindrotheca fusiformis PMID 14703846
Evellerine 20547
WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing PMID 16622405
N2
SARS
DMXL1 promotes recruitment of V1
Fmoc
Cyclosporine inhibits flavivirus replication through blocking the interaction between host cyclophilins and viral NS5 protein PMID 19451286
2
RGMA Human Pre
Identification of Combinations of Protein Kinase C Activators and Histone Deacetylase Inhibitors That Potently Reactivate Latent HIV PMID 32503121
Population Pharmacokinetics of Revefenacin in Patients with Chronic Obstructive Pulmonary Disease PMID 33124005
fgfr4
Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata PMID 22423284
Development of Pyridine
Synthesis, anti
Development of protein degradation inducers of oncogenic BCR
5’
Fenobam a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity PMID 16040814
SS28
HA/Hemagglutinin 蛋白, H1N1 (ADD64203, HEK293, His)
跨膜蛋白 14C（TMEM14C）基因
AF
3
EphB2 抗体 (YA4838)（EphB2 Antibody (YA4838)）
Diethyl carbonate
LDP
PS
Lycopodine 466
locomotor dysfunction
RGFP
Enzymatic formation of glidobactamine a peptide nucleus of glidobactins A, B and C, new lipopeptide antitumor antibiotics PMID 3142842
LDP 341
SC
DW10075
Oprk1
Novel benzoxazole inhibitors of mPGES
H1
Preclinical Evaluation of Artesunate as an Antineoplastic Agent in Ovarian Cancer Treatment PMID 33652561
Leukocyte Ig
ACS81
Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity
A Dual
Exosomes derived from bladder epithelial cells infected with uropathogenic Escherichia coli increase the severity of urinary tract infections (UTIs) by impairing macrophage function PMID 38190378
Tmprss4 Rat Pre
Morinda officinalis oligosaccharides mitigate depression
Aromatic chlorination of omega
Development of TH1 CD4+ T cells through IL
Selective GlyT1 inhibitors discovery of [4
N
Preclinical Development of ADCT
Trazodone impurity 1 (Trazodone 1,4
Synthesis of a 3'
PRIM1
Ecliptasaponin B
Novel ADAM
(+)
Toxicity, bioactivity, release of H2S in vivo and pharmaco
Edoxaban impurity 15 (Edoxaban N
Glutarimide
Rivastigmine N
A photothermal responsive system accelerating nitric oxide release to enhance bone repair by promoting osteogenesis and angiogenesis PMID 39221216
PUMA2A
Effect of N,N,N',N'
Decoquinate
(S)
Fibroblast
MCE
Schisandrin treatment suppresses the proliferation, migration, invasion, and inflammatory responses of fibroblast
beta III Tubulin 抗体 (YA4243)(PBS only)（beta III Tubulin Antibody (YA4243)(PBS only)）
Characterization of the biosynthetic genes for 10,11
A new microbial gluten
Terfenadine N
Protection against endothelial abnormalities by a novel calcium channel blocker, AE0047, in stroke
Downregulation of the long noncoding RNA DSCR9 (Down syndrome critical region 9) delays breast cancer progression by modulating microRNA
Photooxidation of A2
An in vitro profile of activity for the (+) and (
CRK12
3
A Novel Strategy for Preparation of ADSCs
New amide
Blockade of human and porcine myocardial 5
Atf4
SHEDs
Knockdown of hsa_circ_0037658 inhibits the progression of osteoarthritis via inducing autophagy PMID 32980988
Motilin towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists PMID 23189978
Melittin inhibits tumor cell migration and enhances cisplatin sensitivity by suppressing IL
A Core
PD 098059 is a specific inhibitor of the activation of mitogen
MTSS1
Anxa4
Batch and bulk removal of a triarylmethane dye, Fast Green FCF, from wastewater by adsorption over waste materials PMID 18692961
H
Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus PMID 12399480
Mosapride N
The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model PMID 24865335
Antipsychotic effects, side effects and effective dosis of the butyrophenone lenperone (AHR 2277) PMID 561037
Azido
M
Azido
Azido
A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression PMID 26466958
Azido
Azido
Azido
9
Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer PMID 17671208
Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase
Synthesis of novel spirostanic saponins and their cytotoxic activity PMID 18023191
Isoliquiritin suppressed LPS/CuSO4
HA
1R
Cdr2l Mouse Pre
Qrich1
E7010
MK886
N
Ketotifen 34580
Novel inhibitors of the MDM2
Identification of 2
CP809101
Ixabepilone 219989
Dectin
Synthesis of artemisinin dimers using the Ugi reaction and their in vitro efficacy on breast cancer cells PMID 23790541
Synthesis and Biological Evaluation of N
Monosodium glutamate
T98G
Regulation of nucleolar RNA metabolism by hydrocortisone PMID 5776238
ACY
Rational design and synthesis of 2
NSCLC
A new saikogenin from the roots of Bupleurum bicaule PMID 24863358
Involvement of receptor
PF
Functional role of sortilin in myogenesis and development of insulin
PEG10
PSB
Tetramethylfluthrin
Decaethylene glycol (HO
PSB
Angoline a selective IL
Mib1 Rat Pre
Prostaglandin F2α FP receptor antagonist improves outcomes after experimental traumatic brain injury PMID 24172576
NKG2A 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)
First analysis of a bacterial collagen
Proteinase K from Tritirachium album Limber PMID 4373242
Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs PMID 26469188
Senolytics ameliorate the failure of bone regeneration through the cell senescence
mTOR Inhibitors Prevent CMV Infection through the Restoration of Functional αβ and γδ T cells in Kidney Transplantation PMID 34725108
The role of tumor
TPX2 influences the regulation of macrophage polarization via the NF
LDLR 蛋白, Human (HEK293, His)
Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2 PMID 33915015
Discovery of novel transforming growth factor β type 1 receptor inhibitors through structure
Pharmacology of lortalamine, a new potent non
An Omalizumab Biobetter Antibody With Improved Stability and Efficacy for the Treatment of Allergic Diseases PMID 33329588
Ibrolipim 133208
Dexmedetomidine preconditioning ameliorates lung injury induced by pulmonary ischemia/reperfusion by upregulating promoter histone H3K4me3 modification of KGF
D
Vociprotafib 2172652
19(R)
Activation but not blockade of GABAB receptors during early
Activating Sig
IFI16 Induced by p53 Activates the NF
Interleukin
Snrpa
N,N'
ZFP36 无名指蛋白（ZFP36）基因
MYLK4 Human Pre
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy PMID 40116158
RAD50 regulates mitotic progression independent of DNA repair functions PMID 31908056
CD36 蛋白, Human (HEK293, His
The Effect of Lutein on Eye and Extra
Resistance to FOXM1 inhibitors in breast cancer is accompanied by impeding ferroptosis and apoptotic cell death PMID 38980505
In silico predicted compound targeting the IQGAP1
6
Discovery of DS
IFNL1 Human Pre
Photodynamic inactivation mediated by methylene blue or chlorin e6 against Streptococcus mutans biofilm PMID 32407890
Pharmacological characterization of 5
Ddc
Larvicidal activity of isobutylamides identified in Piper nigrum fruits against three mosquito species PMID 11902925
Novel Isoidide Subunit
小核核糖核蛋白多肽 C（SNRPC）基因
Alkaline phosphatase a novel treatment target for cardiovascular disease in CKD PMID 28502983
Cefditoren
STA
Inhibition potential of phenolic constituents from the aerial parts of Tetrastigma hemsleyanum against soluble epoxide hydrolase and nitric oxide synthase PMID 30829084
JARID1D
Discovery of 4
Loss of SDHB Promotes Dysregulated Iron Homeostasis, Oxidative Stress, and Sensitivity to Ascorbate PMID 34127497
CXCL13 as a Novel Immune Checkpoint for Regulatory B Cells and Its Role in Tumor Metastasis PMID 35437281
SM22α
NMT
Fmoc
Prostaglandin FP receptor inhibitor reduces ischemic brain damage and neurotoxicity PMID 22709986
FA 互补组 L（FANCL）基因
Phosphoenolpyruvate
MEOX2 Human Pre
Engineered macrophage membrane
Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin PMID 17953743
Antiplatelet therapy through inhibition of P2Y12 and phosphodiesterase receptors by novel synthesis 1,3
[Effects of protizinic acid on the prostaglandins system and the production of oxygen radicals] PMID 6290356
Synthesis and Evaluation of a 18F
ANP(1
Human neural stem cells restore spatial memory in a transgenic Alzheimer's disease mouse model by an immunomodulating mechanism PMID 38155736
The effect of regadenoson
Sphingomyelin Regulates the Activity of Secretory Phospholipase A2 in the Plasma Membrane PMID 25716287
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids PMID 37871528
DNA repair enzyme OGG1 promotes alveolar progenitor cell renewal and relieves PM2.5
Rhizoma Paridis total saponins alleviate H2O2‑induced oxidative stress injury by upregulating the Nrf2 pathway PMID 31746361
Klrc2
A class of pyrrole derivatives endowed with analgesic/anti
Nonpeptide alphavbeta3 antagonists. 8. In vitro and in vivo evaluation of a potent alphavbeta3 antagonist for the prevention and treatment of osteoporosis PMID 14561098
Lankacyclinol A 52212
Akkermansia muciniphila phospholipid induces homeostatic immune responses PMID 35896748
Norfloxacin hydrochloride 68077
Calcium
Il2rg
Retinobenzoic acids. 2. Structure
Transcriptomics and Metabolomics Identify Drug Resistance of Dormant Cell in Colorectal Cancer PMID 35462906
Herpes simplex virus
KB
Cellular mechanisms of action of mineralocorticoid hormones PMID 1322539
PEG10
Differential regulation of oxidative stress and cytokine production by endothelin ETA and ETB receptors in superoxide anion
Sustainable Antiparasitic Agents from an Agro
Small
Metformin induces diarrhea in mice under over
N
The cAMP capture compound mass spectrometry as a novel tool for targeting cAMP
Engineering CD276/B7
FCE
Rnf43
Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors A Lead Optimization Case Study PMID 26455919
TCS
Tedizolid Activity Against Clinical Mycobacterium abscessus Complex Isolates
subdural
CD146 抗体 (YA544)（CD146 Antibody (YA544)）
Linolelaidic acid 506
SRRM2 phase separation drives assembly of nuclear speckle subcompartments PMID 38381607
Locomotion
GNF156
MMP
parasitic disease
MAL II
溶质载体家族 44 成员 3（SLC44A3）基因
血小板活化因子乙酰水解酶 1b 催化亚基 3（PAFAH1B3）基因
胰岛素样生长因子结合蛋白 2（IGFBP2）基因
N
REC114 减数分裂重组蛋白（REC114）基因
CHI3L1
Triptolide
Schwann cell
1
TG (18 2_20 3_20 4)
CDK2
Inhibition of NLRP3 Inflammasome Ameliorates Cerebral Ischemia
Sex
Efbemalenograstim alfa 2200269
Small molecule
DEPRESSION OF THE PRIMARY IMMUNE RESPONSE BY DL
DNA staining
PA
The critical role of Id2 gene in mesenchymal stem cell therapy for colitis through regulating immune response and microbiota PMID 40450917
bacterial staining
The endoplasmic reticulum structure, function and response to cellular signaling PMID 26433683
The Destruction Of Laser
Xanthan Gum Ameliorates Osteoarthritis and Mitigates Cartilage Degradation via Regulation of the Wnt3a/β
PfDHODH
细胞周期蛋白 L1（CCNL1）基因
角蛋白 19（KRT19）基因
THO 复合亚基 7（THOC7）基因
Ssbp1
MCE
140290
粘蛋白 1（TEKT1）基因
外泌体组分 1（EXOSC1）基因
TEPSIN 适配器相关蛋白复合物 4 辅助蛋白（TEPSIN）基因
马球样激酶 4（PLK4）基因
线粒体裂变调节因子 1（MTFR1L）基因
RAN 结合蛋白 10（RANBP10）基因
无名指蛋白 20（RNF20）基因
MYST/Esa1 相关因子 6（MEAF6）基因
Reprogramming of endometrial adult stromal cells in the presence of a ROCK inhibitor, thiazovivin, could obtain more efficient iPSCs PMID 25490878
BMS
多功能 ROCO 家族信号调节器 1（MFHAS1）基因
溶质载体家族 9 成员 B2（SLC9B2）基因
CWC15 剪接体相关蛋白同系物（CWC15）基因
卵形锌指 2（OVOL2）基因
Enc1
Toward orthopoxvirus countermeasures a novel heteromorphic nucleoside of unusual structure PMID 16821766
Quilizumab
Xylose
SMYD1 Human Pre
Cyclo(Ala
CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK
Exendin
Antifungal activity and mechanism of novel peptide Glycine max antimicrobial peptide (GmAMP) against fluconazole
Synthesis and biological activity of olomoucine II PMID 12392733
The Chinese herb isolate yuanhuacine (YHL
PRMT4 inhibitor TP
Antiplatelet and antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa receptor antagonist PMID 8281661
Cholesterol 25
Role of neuroglia cell
ANAPC5 mitigates acute lung injury through regulating macrophage M1/M2 polarization via the EGFR/CD24 axis PMID 40834712
PT3 2710273
UC3
Enduring glucocorticoid
Ustusolate E
CPS
fennel
Picomolar bivalent inhibitors of protein kinase CK2 active against β
Crocein Orange G mediated detection and modulation of amyloid fibrillation revealed by surface
Stejnulxin, a novel snake C
TBC1D23 Human Pre
Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL
SAE14
L
Cytotoxic clerodane diterpenes from Zuelania guidonia PMID 24484281
Monascuspiloin enhances the radiation sensitivity of human prostate cancer cells by stimulating endoplasmic reticulum stress and inducing autophagy PMID 22802963
CDCA2 acts as an oncogene and induces proliferation of clear cell renal cell carcinoma cells PMID 32194746
Thioridazine, an antipsychotic drug, elicits potent antitumor effects in gastric cancer PMID 24604290
1,2
MICU3 regulates mitochondrial Ca2+
3
YU241279
Post
Regulated IRE1
Chemoproteomics
RIPK1 regulates cell function and death mediated by UVB radiation and TNF
Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3 and 20S,23R(OH)2D3 PMID 35168121
Perfluorooctane sulfonic acid impairs spermatogenesis via the liver
Lonicerin alleviates ovalbumin
Toxic hazard from formulating the insecticide dimethoate in methyl 'Cellosolve' PMID 13691285
Tafluprost ethyl ester 209860
Cathepsin C
Hypusine 34994
Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure Its Beneficial Effects on ACE2/Ang(1
A stimuli
Desvenlafaxine another me too drug? PMID 18698015
14
In vitro differentiation of retinal cells from human pluripotent stem cells by small
Investigations on the 4
Cardiovascular effects of bevantolol, a selective beta 1
LSD1 is required for euchromatic origin firing and replication timing PMID 35414135
含无菌 alpha 基序结构域 7（SAMD7）基因
Dasatinib exacerbates splenomegaly of mice inoculated with Epstein
Schizandrin reverses memory impairment in rats PMID 17705144
Design, synthesis and pharmacological characterization of coumarin
Bis(1,8
Angenomalin 18199
NOTCH1 combined with chemotherapy synergistically inhibits triple
Jietacin A 109766
Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer PMID 34623971
CB1R
Monoclonal antibodies specific for kappa chain, lambda chain, and IgG1 of human gammaglobulin PMID 6167543
Formononetin, a bioactive isoflavone compound in modified nuanxinkang, alleviates cardiorenal syndrome type 4
Mylk4 Rat Pre
The BRCA1/BARD1 heterodimer modulates ran
Prophylactic and therapeutic activity of alkaline phosphatase in arthritic rats single
ZDHHC5 Human Pre
生长分化因子 6（GDF6）基因
Dynamic substrate topographies drive actin
AYK004 3031612
NAPQI 50700
无名指蛋白 2（RNF2）基因
GTF2IRD1 Human Pre
The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor PMID 6424715
Non
IL
Effects of miltefosine on the proliferation, ultrastructure, and phospholipid composition of Angomonas deanei, a trypanosomatid protozoan that harbors a symbiotic bacterium PMID 22651853
ESAM Human Pre
Levalbuterol 34391
Comparison of the effects of thioridazine and mesoridazine on the QT interval in healthy adults after single oral doses PMID 17410120
NAPQI (Standard)
Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, an Intravenous Potentiator, after Single and Multiple Ascending Doses and When Combined with β
2
Optimization of a urea
Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC
Developmental toxicity and transcriptome analysis of 4
SORT1
Experimental respiratory tract infection with Klebsiella pneumoniae DT
AM095 1345614
Rilmenidine a clinical overview PMID 10921529
Mapre1
Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy PMID 38387527
Fmoc
New Cytotoxic Alkylated Chalcones from Fatoua villosa PMID 28371315
Ac
Cbz
FGFC1 overcomes Ara
Subcellular compartmentation of the diterpene carnosic acid and its derivatives in the leaves of rosemary PMID 11161064
Effect of NG
Chloroplast precursor protein preClpD overaccumulation triggers multilevel reprogramming of gene expression and a heat shock
Adenosine deaminase, microorganism 9026
NF
3
Panaxadiol 19666
Structure of a nanobody
Metabolic Rewiring by Loss of Sirt5 Promotes Kras
2',7'
Genetic variants in interleukin 7 receptor α chain (IL
Heat shock factor 1 inducers from the bark of Eucommia ulmoides as cytoprotective agents PMID 23847077
Beta
Interactions of calcium antagonists and the calcium channel agonist Bay K 8644 on neurotransmission of the mouse isolated vas deferens PMID 2466518
MCE
六个同源框 5（SIX5）基因
酰基辅酶 A 硫酯酶 12（ACOT12）基因
152206
脊索同源框（NOTO）基因
OC2
Misp Mouse Pre
Pharmacokinetic Drug Interaction Studies with Enzalutamide PMID 25929560
attachment
DBCO
Mtss1
30014
TPE
MKC8866 (Standard)
Escitalopram impurity 2 ((S)
N
Gut inflammation promotes microbiota
4
白细胞介素 36 受体拮抗因子（IL36RN）基因
Deoxynyboquinones as NQO1
Gpd2
Forsythia suspensa fruit extracts and the constituent matairesinol confer anti
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