最近收录_第899页_生物活性分子
生物活性分子最近更新
TGM2 Enhances Hypobaric Hypoxia
Edutirsen 3034567
MCE
Delta
2,4,6
HY
Development of an Orally Active Small
Assessment of Some Unsymmetrical Porphyrins as Promising Molecules for Photodynamic Therapy of Cutaneous Disorders PMID 38256895
The Rationale for Using Neridronate in Musculoskeletal Disorders From Metabolic Bone Diseases to Musculoskeletal Pain PMID 35805927
Epstein
all
Menin
AChE
AN
Discovery of a novel nicotinamide phosphoribosyl transferase (NAMPT) inhibitor via in silico screening PMID 24389478
Synthesis, structure
WCF
Benzene, coumarin and quinolinone derivatives from roots of Citrus hystrix PMID 23352239
SER
AGC1
核糖体蛋白 L15（RPL15）基因
23 型蛋白酪氨酸磷酸酶非受体（PTPN23）基因
POP5 同系物，核糖核酸酶 P/MRP 亚基（POP5）基因
线粒体定位富谷氨酸蛋白（MGARP）基因
RNA 结合基序蛋白 22（RBM22）基因
enkurin, TRPC 通道相互作用蛋白（ENKUR）基因
Hacd3
分泌相关的 Ras 相关 GTPase 1B（SAR1B）基因
跨膜蛋白 65（TMEM65）基因
含锌指 CCCH 型和 G 补丁域（ZGPAT）基因
GH3
Aramisulpride hydrochloride 2129505
ZFP42 锌指蛋白（ZFP42）基因
An Unbiased Immunoaffinity
Isolation and Culture of Cranial Neural Crest Cells from the First Branchial Arch of Mice PMID 35530521
In vitro and in vivo activity of chelerythrine against Candida albicans and underlying mechanisms PMID 31992072
Dexamethasone
AKP
janus 激酶和微管相互作用蛋白 1（JAKMIP1）基因
Interleukin
Thiopyrano[2,3
Nanosilver induces the formation of neutrophil extracellular traps in mouse neutrophil granulocytes PMID 31408819
Hepatocyte
ILK
YCH3971
CT
Dimethoxane
Cinnamoyl
Anticancer agent 314
TKL002
Furathiocarb (呋线威)
(S)
Rps5
Itpkb
NickFect2
泛素 B（UBB）基因
FLT3
NickFect1
Clenproperol
epi
Mal
Cooperative nuclear import of duck plague virus DNA polymerase subunits pUL42 NLS Enhances pUL30 nuclear import and viral replication, with VP22 as a compensatory factor PMID 40526994
The pharmacokinetics of oxypurinol in people with gout PMID 22300439
Design and development of multitarget
PMA inhibits endothelial cell migration through activating the PKC
泛酸激酶 1（PANK1）基因
Ch282
Inhibitor of DNA
Long non
Human carbonic anhydrase
MCE
The ecotin
Anti
Desethyl chloroquine
Specific Targeting of Proerythroblasts and Erythroleukemic Cells by the VP1u Region of Parvovirus B19 PMID 26240997
ER
BMS
Cryptophycin 52 (LY355703)
Linoleylanilide (Linoleic acid anilide)
Antibody
Antiproliferative agent
P
Gdf9
Propafenone
HCAR1抑制剂、基因
(S,S,S,S,R)
NKCC激活剂、基因
Modified Vaccinia virus Ankara but not vaccinia virus induces chemokine expression in cells of the monocyte/macrophage lineage PMID 25889495
Tetrabutylammonium salicylate 22307
CRBN ligand
Enhanced resistance to Ca2+
MK
MAGL
Fluorescent microplate assay for cancer cell
NBI
The NLRP3 Activation in Infiltrating Macrophages Contributes to Corneal Fibrosis by Inducing TGF
CP
Therapeutic Perspectives of 8
Oxysterols are allosteric activators of the oncoprotein Smoothened PMID 22231273
Topical application of retinyl palmitate
[Tetragastrin activation of rat gastric mucosa adenyl cyclase in vitro] PMID 7260361
Duloxetine alleviates oxaliplatin
Cudraxanthone D 96552
N
Piperacillin mixture with tazobactam (8 1) (哌拉西林/他唑巴坦 (8 1))
AD
Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation PMID 37891461
Rational Design and Synthesis of Isoxazoline Derivatives with Low Bee
Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands PMID 24285541
GNF6702
Mal
DNA Polymerase Alpha, Human
Clusterin maintains hemostatic equilibrium by stabilizing VWF multimers in plasma PMID 41557908
HABP2 Encapsulated by Peripheral Blood
Abscisic acid
4
Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro
Discovery of a new class of highly potent inhibitors of acid ceramidase synthesis and structure
Fabrication and Properties of a Biomimetic Dura Matter Substitute Based on Stereocomplex Poly(Lactic Acid) Nanofibers PMID 32547025
pep
Lanosterol 14α
Carboxyl diazirine alkyne 1450754
The Novel KV7.2/KV7.3 Channel Opener ICA
Novel cinnamaldehyde
CRBN ligand
BTLA/CD272 蛋白, Human (HEK293, His)
Dimethyl fumarate alleviate hepatic ischemia
splice
Firefly luciferase
Biotin
MK
Pharmacokinetics of 1
Hit
Role of Pannexin
A genome
Glycyrrhizin alleviates brain injury in necrotizing enterocolitis model mice by suppressing HMGB1/TLR4 pathway PMID 39970710
The Class III PI3K/Beclin
弗洛替林 2（FLOT2）基因
LP 10
SRI
Sipeimine reduces ethanol
IL
JMS
Propargyl
The STAT3 pathway as a therapeutic target in head and neck cancer Barriers and innovations PMID 26733183
Aloeresin J
Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance PMID 18172311
The interaction of O
O
PARP7 inhibition stabilizes STAT1/STAT2 and relieves experimental autoimmune encephalomyelitis in mice PMID 40811059
Notch3
Discovery andw biological evaluation of novel 6,7
Selective covalent targeting of GPX4 using masked nitrile
N
TRPA1 Covalent Ligand JT010 Modifies T Lymphocyte Activation PMID 38927036
Solution conformations of two naturally occurring RNA nucleosides 3
CXCL16 蛋白, Human (HEK293, Fc)
Electroacupuncture preconditioning alleviates myocardial ischemia
A re
Cathepsin B inhibition limits bone metastasis in breast cancer PMID 22266111
MYPT1
NP396
SRRT Human Pre
Enhancement of lithium elimination by multiple
DSM265
Gramine
N3
IL
Tyrosinase
Antifibrillatory efficacy of ersentilide, a novel beta
Empagliflozin alleviates obesity
Scoparone induces autophagic cell death via the PAK1/AKT axis in colorectal cancer PMID 37805132
Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter
Hyperuricemia causes kidney damage by promoting autophagy and NLRP3
HDAC8
Trimidox hydrochloride 95933
SARS
2
Some distal limb structures develop in mice lacking Sonic hedgehog signaling PMID 11118883
CCI1008
Effect of U50488, a selective kappa opioid receptor agonist and levetiracetam against lithium
Symplekin, a novel type of tight junction plaque protein PMID 8769423
Rnf43 Mouse Pre
MCE
Structure of an anti
APC 膜募集蛋白 1（AMER1）基因
Lum
PI55
N
LAPTc
Deschlorohaloperidol (R
Ankrd1 Rat Pre
ortho
Osteocytes/Osteoblasts Produce SAA3 to Regulate Hepatic Metabolism of Cholesterol PMID 38613835
An exploration of solvent
Discovery and antitumor activity of Benzo[d]imidazol
A human protein
Polysorbate80
Discovery of isoquinolinone and naphthyridinone
Enniatin B 917
Anti
Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response PMID 25530830
Kaempferol and Kaempferide Attenuate Oleic Acid
Lignan and coumarin glycosides from Haplophyllum suaveolens PMID 11421445
Efimosfermin alfa 2765640
IL
蛋白磷酸酶 2 调节亚基 Balpha（PPP2R2A）基因
PGE 9262932
Discovery of Pyrazolone Carbothioamide Derivatives as Inhibitors of the Pdr1
IL
Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK
β
A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes PMID 31999380
Characterization of novel L
MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53 PMID 27659536
Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5 PMID 19297521
In vivo antitumor activity of two new seven
Small
Glucagon
N
The role of tRF
Choline Salicylate Analysis Chemical Stability and Degradation Product Identification PMID 31877863
Triphenylamine 603
Carrot seed oil
Fenobam sulfate inhibits cocaine
Examining the inhibitory potency of food additive fast green FCF against amyloid fibrillogenesis under acidic conditions PMID 27824368
Activation of the thyrotropin
Elucidation of Inverse Agonist Activity of Bilastine PMID 32521742
DS
Facilitation of morphine withdrawal symptoms and morphine
Icariside II induces cell cycle arrest and differentiation via TLR8/MyD88/p38 pathway in acute myeloid leukemia cells PMID 30579933
M2 Polarization of RAW264.7
carp
Monoolein
Electrical stimulation and piezoelectric biomaterials for bone tissue engineering applications PMID 32810650
Protective effect of tubuloside B on TNFalpha
Probenecid, a gout remedy, inhibits pannexin 1 channels PMID 18596212
Discovery and Synthesis of a Pyrimidine
CD55/DAF 蛋白, Rat (HEK293, Fc)
CD200R1 蛋白, Human (HEK293, His)
Modeling post
Norfloxacin succinil 100587
Amphiregulin 蛋白, Mouse (HEK293, Fc)
A Cyanobacteria
Zuclomiphene citrate 7619
NAD+ exhaustion by CD38 upregulation contributes to blood pressure elevation and vascular damage in hypertension PMID 37718359
Discovery of a novel series of pyridone amides as NaV1.8 inhibitors PMID 38350529
(rel)
MicroRNA
Reduced thymocyte development in sonic hedgehog knockout embryos PMID 14764698
ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension PMID 28910144
Stimulating Effect of Elvitegravir on Suicidal Erythrocyte Death PMID 26963694
Unique functions of Sonic hedgehog signaling during external genitalia development PMID 11684660
Biotransformation of an antihypertensive arylalkylamine analogue in the rat PMID 9849643
UAB116
The Anti
Discovery of 2
BTK gatekeeper residue variation combined with cysteine 481 substitution causes super
CDH3
A long
Microcystin
Dihydroartemisinin inhibits the development of colorectal cancer by GSK
Anti
The effect of autophagy activation on apoptosis and myofibrillar structural proteins during the post
MCE
8,8''
LINC01605 knockdown induces apoptosis in human Tenon's capsule fibroblasts by inhibiting autophagy PMID 35401799
A minimalist and robust chemo
Tylvalosin exhibits anti
Synthesis and biological evaluation of acyclic 3
Short
Tanshinone IIA regulates fibroblast proliferation and migration and post
Hydroxysafflor yellow a confers neuroprotection against acute traumatic brain injury by modulating neuronal autophagy to inhibit NLRP3 inflammasomes PMID 36842723
VGF and Its C
Oleuropein as an inhibitor of peroxisome proliferator
Olfactory detection of ursodeoxycholic acid (UDCA) in large yellow croaker (Larimichthys crocea) responses, pathways, and receptor functions PMID 40995806
PRR3 Human Pre
Ifnl3 Mouse Pre
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF
Human bone marrow mesenchymal stem cell
Astrocytic TSPO Upregulation Appears Before Microglial TSPO in Alzheimer's Disease PMID 32804124
The TRPM7 chanzyme in smooth muscle cells drives abdominal aortic aneurysm in mice PMID 39953275
DSM
Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models PMID 39605494
The Specific Mitogen
Splicing activates transcription from weak promoters upstream of alternative exons PMID 37301863
BD
GW768505A free base 501693
GPVI 蛋白, Human (HEK293, His)
Synergistic Effect of an Antisense Oligonucleotide and Small Molecule on Splicing Correction of the Spinal Muscular Atrophy Gene PMID 38379891
Trichostatin A modulates the macrophage phenotype by enhancing autophagy to reduce inflammation during polymicrobial sepsis PMID 31677992
The role and mechanism of hyperoside against myocardial infarction in mice by regulating autophagy via NLRP1 inflammation pathway PMID 33957207
Exploring the impact of Apelin and Reactive Oxygen Species on autophagy and cell senescence in pre
Sadopine 111127
Mutant LRRK2 exacerbates immune response and neurodegeneration in a chronic model of experimental colitis PMID 37289222
Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A PMID 18752940
The human beta
Arcn1 Mouse Pre
含 EF 手域 1（EFHC1）基因
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN
CircPAN3 contributes to drug resistance in acute myeloid leukemia through regulation of autophagy PMID 31401408
CALML3
Hepatic Leucine Carboxyl Methyltransferase 1 (LCMT1) contributes to high fat diet
减数分裂双链断裂形成蛋白 4（MEI4）基因
CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs PMID 22929806
STA9090
KA
Mesencephalic astrocyte
Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist PMID 15226502
DsbA
1
L
Responses of Dendroctonus brevicomis (Coleoptera Curculionidae) in behavioral assays implications to development of a semiochemical
Tet methylcytosine dioxygenase 1 modulates Porphyromonas gingivalis
RNF4
Effects on K+ currents in rat cerebellar granule neurones of a membrane
STAT3 phosphorylation
Isolation, Identification, and Anti
Chemical carcinogenicity of neodymium nitrate in AML12 hepatocytes Dose
Apcin 300815
[Effect of clofarabine on proliferation and Bcl
NADPH oxidase 1/4 dual inhibitor setanaxib suppresses platelet activation and thrombus formation PMID 39293714
The synergic inhibitory effects of dark tea (Camellia sinensis) extract and p38 inhibition on the growth of pancreatic cancer cells PMID 31777585
Identification and Mechanism Elucidation of Anti
FTO regulates testosterone secretion in Leydig cells insights into the role of m6A modifications and the therapeutic potential of hCG PMID 40993667
Surfactin C2
丝氨酸/苏氨酸激酶 10（STK10）基因
PROTAC BRD9
Dysregulation of Macropinocytosis Processes in Glioblastomas May Be Exploited to Increase Intracellular Anti
β2AR against myocarditis
Tpl2 Kinase Inhibitor 1 hydrochloride 2934185
Koaburaside monomethyl ether 41514
Bromo
In search of negative allosteric modulators of biological targets PMID 18973826
1
Hoxc8 Mouse Pre
Regulation of KDM5C stability and enhancer reprogramming in breast cancer PMID 36192394
Role of C
GSK1521498 free base hydrochloride 1007578
Azido
Kinetics of subtilisin and thiolsubtilisin PMID 6343835
MRS4654 2765570
FGFR3
DJ
Antibacterial agent 103 2396409
5
SPOPL Human Pre
Resveratrol Relieves Gouty Arthritis by Promoting Mitophagy to Inhibit Activation of NLRP3 Inflammasomes PMID 34335041
HBQ1
Triclosan inhibits testosterone biosynthesis in adult rats via inducing m6A methylation
LCI765 870194
ACAN
1,3,5,6
CHUK 抗体 (YA3520)（CHUK Antibody (YA3520)）
Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition PMID 27479743
Substituted pyrazoles as hepatoselective HMG
Mitochondria
Protective effect of E3330, a novel quinone derivative, in galactosamine
Neuroprotective and Anti
Zomepirac sodium salt 64092
Acupoint catgut embedding improves senescence in a rat model of ageing by regulating mitophagy via the PINK1 pathway PMID 33645011
Fmoc
progeny
Acan Mouse Pre
Identification of a Novel Benzimidazole Pyrazolone Scaffold That Inhibits KDM4 Lysine Demethylases and Reduces Proliferation of Prostate Cancer Cells PMID 28346812
Notch1 Inhibits Rosiglitazone
Potent anti
Creatine
Application of electrochemical LAMP
ENSA Human Pre
micro water pool
ESRP1 and ESRP2 are epithelial cell
Scutellaria baicalensis root extract 94279
Combination of 3
Fdx1 Mouse Pre
Regenerable sensor based on tris(4,7'
Minoxidil hydrochloride 69935
Benzyl
VLS
Vonafexor 1192171
Desmethyl cariprazine
Solcitinib 1206163
Segregation of the classical transmitters norepinephrine and acetylcholine and the neuropeptide Y in sympathetic neurons modulation by ciliary neurotrophic factor or prolonged growth in culture PMID 20715153
A Screen of FDA
Synthesis of novel substituted purine derivatives and identification of the cell death mechanism PMID 25462277
Evaluation of the adverse effects of oral firocoxib in healthy dogs PMID 17472653
Diethyl
Discovery of Potent Selective HDAC6 Inhibitors with 5
Efficiently targeted therapy of glioblastoma xenograft via multifunctional biomimetic nanodrugs PMID 36461108
Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities PMID 27210430
Beneficial effect of fibronectin administration on chronic nephritis in rats PMID 2346523
NLRP12 decreases TRIM25
Antigen coupled with Lewis
Fragment
DOX
Resveratrol protects against myocardial ischemic injury in obese mice via activating SIRT3/FOXO3a signaling pathway and restoring redox homeostasis PMID 38520872
H
Chondroprotective and antiarthritic effects of galangin in osteoarthritis An in vitro and in vivo study PMID 34090897
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours PMID 12471003
Propofol protects cardiomyocytes from doxorubicin
AES350
Ferrous sulfate
Xanthotoxol alleviates secondary brain injury after intracerebral hemorrhage by inhibiting microglia
Knockdown of circ_0000372 elevates PD
Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule
parasite inhibitor
Chelerythrine chloride induces apoptosis in renal cancer HEK
Unhydrolyzable analogues of adenosine 3' 5'
The antioxidant ergothioneine alleviates cisplatin
Tubb3 Rat Pre
RNA G
SQ 31844 115766
Pharmacology of orismilast, a potent and selective PDE4 inhibitor PMID 36527389
鞘氨醇激酶 1（Sphk1）基因
Antitumor activity of a systemic STING
4
Treg Immunomodulation Contributes to the Anti
Cytotoxic and other compounds from Didymochlaena truncatula from the Madagascar rain forest PMID 16499333
Development of a series of novel 4
Genomic Analysis and Functional Validation of Bidirectional Promoters in Medaka (Oryzias latipes) PMID 39769487
蔗糖
Identification of chelerythrine as an inhibitor of BclXL function PMID 12702731
S100a4
Drotokibart 2925270
Brain endopeptidase generates enkephalin from striatal precursors PMID 6750568
Engineered mitochondria exert potent antitumor immunity as a cancer vaccine platform PMID 39164536
PRKDC 抗体 (YA4136)（PRKDC Antibody (YA4136)）
Kasugamycin hydrochloride 19408
RNF43
gallate
2
Isoquinoline
Programmable translational inhibition by a molecular glue
IKAROS 家族锌指 4（IKZF4）基因
Diversification of phenolic glucosides by two UDP
Inhibitory effects of curcumenol on human liver cytochrome P450 enzymes PMID 20148399
GC 14 447415
Cyflufenamid 180409
Hexanal propylene glycol acetal 1599
4
GNE
Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert
(S)
Dicamba
Erbulozole
WAY
N
4,4'
Cyproterone acetate induces a cellular tolerance to cadmium in rat liver epithelial cells involving reduced cadmium accumulation PMID 11551428
MKI
P
EPZ020411 dihydrochloride
L
TRK
Apoptosis inducer 42 66685
A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells PMID 40117373
Terephthalic acid impurity 1 29278
MELK Promotes Melanoma Growth by Stimulating the NF
忍者 2（NINJ2）基因
60491
Design, synthesis and evaluation of novel 5
Pyrrolo
Glucarpidase 1622456
The angiotensin receptor neprilysin inhibitor LCZ696 attenuates renal fibrosis via ASK1/JNK/p38 MAPK
双性和 mab
Molecular modeling aided design of nicotinic acid receptor GPR109A agonists PMID 18760600
Evidence that the anti
Combined Metabolomic and Transcriptomic Analysis Reveals Allantoin Enhances Drought Tolerance in Rice PMID 36430648
Antagonizing STAT3 activation with benzo[b]thiophene 1, 1
Serum thyroid
HY
Characterization of the cellular action of the MSK inhibitor SB
Integrin α5 抗体 (YA5131)（Integrin α5 Antibody (YA5131)）
Identification of a substrate of the renal tubular transporters for detecting drug
Amezinium methylsulfate (Amezinium metilsulfate)
KRAS mRNA Spleen
Treosulfan 299
Interleukin
TcO
Biological characteristics of manganese transporter MntP in Klebsiella pneumoniae PMID 38888334
Enzyme
Retinoic acid is a high affinity selective ligand for the peroxisome proliferator
C.I. Pigment yellow 97 12225
Involvement of Bim in Photofrin
BMP
Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors PMID 24982761
Fmoc
Short loop length and high thermal stability determine genomic instability induced by G
Limonin attenuates the stemness of cervical carcinoma cells by promoting YAP nuclear
ICI 174864 89352
Hemagglutinin (48
New insights into the effect of bisphenol AF exposure on maternal mammary glands at various stages of gestation in mice PMID 35934037
An active metabolite of oltipraz (M2) increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK PMID 23145499
Design, Synthesis, and Evaluation of Thiazolidine
5
Synthesis and biological evaluation of 1,2
Targeting interleukin
Targeting the SOX9/TIMP1 Axis with iRGD
Two new xanthones from Swertia angustifolia PMID 22296155
A novel oral indoline
共927页
首页
上一页
904
903
902
901
900
899
898
897
896
895
894
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新