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Ursonic acid methyl ester 989
Endoxifen, the active metabolite of tamoxifen, inhibits cloned hERG potassium channels PMID 25680947
Hypoxia
P2X7R Mediates the Synergistic Effect of ATP and MSU Crystals to Induce Acute Gouty Arthritis PMID 36686377
Evaluation of intermediate compounds in β
Xanthomicrol 16545
Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy PMID 17099729
Protective effect of Pterostilbene against free radical mediated oxidative damage PMID 24070177
Ras
The Therapeutic Potential of Piceatannol, a Natural Stilbene, in Metabolic Diseases A Review PMID 28387565
1,5,6
Pemetrexed disodium hemipenta hydrate 357166
magnesium
Oncostatin M a pleiotropic cytokine in the central nervous system PMID 15450253
Cowaxanthone B 212842
Elaborate cooperation of poly(rC)
Smad1
Maresins novel macrophage mediators with potent antiinflammatory and proresolving actions PMID 19103881
Pank1
New phenanthrene derivatives with nitric oxide inhibitory and radical
SB
Polyoxyethylene tridecyl ether 78330
Evoxanthine 477
Synthesis and Photophysical Properties of Bipolar Compound Triphenylamine/Diazafluorene
Modulation of ionotropic GABA receptors by 6
MeOSuc
Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation PMID 29712923
Defining optimal sulbactam regimens for treatment of Acinetobacter baumannii pneumonia and impact of blaOXA
Age dependency of cerebral P
mTOR signaling pathway regulation HIF
Effect of lipoxygenase inhibitors and leukotriene antagonists on acute and chronic gastric haemorrhagic mucosal lesions in ulcer models in the rat PMID 8912128
Prevention of renal ischemia and reperfusion injury by penehyclidine hydrochloride through autophagy activation PMID 32186764
Ferroptosis in health and disease PMID 38908072
Induction of tumor necrosis factor receptor type 2 gene expression by tumor necrosis factor
Development of specific antisera and a radioimmunoassay procedure for the gonadotropin
Dorsomorphin inhibits AMPK, upregulates Wnt and Foxo genes and promotes the activation of dormant follicles PMID 38902324
Protein lactylation of citrate synthase promotes the AKI
Inhibition of N
Synthesis and antiarrhythmic activity of novel 3
Acid blue 9 (diammonium)
TRK
Role of Netrin
Haliangicin A 290354
岩藻糖基转移酶 7（FUT7）基因
Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer PMID 22279038
Activated Schwann cells promote tumor growth in colon cancer PMID 40349909
ZED
2
Biochemical profiling of anti
Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles PMID 29059541
Tetrahdroxysqualene from Rhus taitensis shows antimycobacterial activity against Mycobacterium tuberculosis PMID 18710283
DesArg10[Hoe 140] is a potent B1 bradykinin antagonist PMID 1334341
human P2X2
Sequences of cytotoxic T
C
P37 protein
DCPIB (Standard)
Ethyl nicotinate hydrochloride
SG3400 delate(Mal
ML218 (Standard)
ENSA 蛋白, Human (His)
Glycochenodeoxycholic acid sodium salt 16564
N1
Tubeimoside I induces accumulation of impaired autophagolysosome against cervical cancer cells by both initiating autophagy and inhibiting lysosomal function PMID 30389907
S
Urolithin a attenuates rheumatoid arthritis by inhibiting inflammation and pyroptosis in fibroblasts via the AMPK/ NF
Dosing
A thiol probe for measuring unfolded protein load and proteostasis in cells PMID 28883394
1
Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines PMID 20458760
Viral protein R inhibitors from Swertia chirata of Myanmar PMID 31076338
Montixanthone
MitoQ
1,3,5
A mouse model with age
Thrombospondin sequence motif (CSVTCG) is responsible for CD36 binding PMID 1371676
3
Bac2A TFA 231306
GS
UBE2C
Role of the SPI1/CDKN2A/p53 signaling pathway in cuproptosis of lung adenocarcinoma cells PMID 40438868
Pyruvic acid
Silibinin alleviates ferroptosis of rat islet β cell INS
PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production PMID 38480845
CL5D 2488745
Xanthomicrol is the main cytotoxic component of Dracocephalum kotschyii and a potential anti
TSH Activates Macrophage Inflammation by G13
Monitoring SARS
NSC
(4
Mycoepoxydiene suppresses HeLa cell growth by inhibiting glycolysis and the pentose phosphate pathway PMID 28224194
Fludarabine triphosphate 74832
Co
8
S
An Indole
2,5
The potential of TAOK1 as a new therapeutic target for the treatment of cancer cachexia
Retinoic acid alters the mechanism of attachment of malignant astrocytoma and neuroblastoma cells to thrombospondin
Identification of Functional Food Factors as β2
MSC derived EV loaded with miRNA
rel
Piceatannol, a natural trans
Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay PMID 23691032
Bispyribac
Tralomethrin causes cardiovascular toxicity in zebrafish (Danio rerio) embryos PMID 37471628
Montixanthone 876305
Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51
D
Antimanic
Study of the analgesic effect of lanepitant in patients with osteoarthritis pain PMID 10801252
miR
1
Effects of fenspiride on human bronchial cyclic nucleotide phosphodiesterase isoenzymes functional and biochemical study PMID 9489859
Antimicrobial and antioxidant activities of Gentianella multicaulis collected on the Andean Slopes of San Juan Province, Argentina PMID 22486039
S
Salicylaldehyde Suppresses IgE
VAL
AZGP1
Escherichia coli Nissle 1917 ghosts alleviate inflammatory bowel disease in zebrafish PMID 37473802
MKI3
Discovery of tyrosine
Inhibitors of anthrax lethal factor PMID 17574849
Reconstitution of human pyroptotic cell death in Saccharomyces cerevisiae PMID 36813876
Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis PMID 11520664
ALN
Boc
FAM NHS ester, 6
Substituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase PMID 31212181
Theasinensin C Mitigates HFrD
R
AAK1
A copper(I)
Fuscaxanthone C
N
Azido
DISC
ZNF281 Human Pre
RNF112 Human Pre
µ
R
bush beans
IRX3 controls a SUMOylation
Pigmentation Inhibitor
D 473
initial discharge capacity
CCT368772
VLS
PANK4 Human Pre
EBNA3B 399
Magnesium and zinc borate enhance osteoblastic differentiation of stem cells from human exfoliated deciduous teeth in vitro PMID 29119879
L
Ivd Rat Pre
Myo
HHT (Standard)
CHAC1 Human Pre
NUAK1
CTR/AMYR agonist
HET0016
Gdf9 Rat Pre
Passive immunotherapy with a novel antibody against 3pE
DBCO
Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs PMID 38692057
UFC1 Human Pre
Effects of EMD 57033 on contraction and relaxation in isolated rabbit hearts PMID 7586281
4
Structure
Pdcd6
Jun 15716
MC38 mice
Isobellidifolin
Inhibition of autophagy by 3
Azido
PANK1 Human Pre
TNIK modulator
ML402 (Standard)
TRK
CDK9
Ozolinone 56784
ALK5
Characterization of the Aquaporin
Repurposing Drugs in Oncology (ReDO)
Benzyl
Melanocortin Receptor Agonists Facilitate Oxytocin
Negative regulation of TREM2
Discovery of Novel HDAC3 Inhibitors with PD
S100Z Human Pre
Aminopyrrolidineamide inhibitors of site
Matricaria chamomilla L. Ameliorates Asthma by Protecting OVA
FOXA2
Pyrroloquinoline Quinone Inhibits Rotenone
Beclin‑1 exerts protective effects against cerebral ischemia‑reperfusion injury by promoting DNA damage repair through a non‑autophagy‑dependent regulatory mechanism PMID 35266018
Light
Nigericin Induces Paraptosis
Stomatin
sPLA2
Atractylodes lancea Rhizome Polysaccharide Alleviates MCD Diet
Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia
Chemo
Phenotypic change caused by transcriptional bypass of uracil in nondividing cells PMID 10102819
DNA hypermethylation
WHSC1L1
Effect of uracil on metabolism of 5
Genome
Aminooxy
Ruboxistaurin LY 333531 PMID 17472415
Autophagy A New Mechanism for Esketamine as a Depression Therapeutic PMID 35597333
Calreticulin
Direct moxibustion exerts an analgesic effect on cervical spondylotic radiculopathy by increasing autophagy via the Act A/Smads signaling pathway PMID 35315239
Zebrafish mylipb attenuates antiviral innate immunity through two synergistic mechanisms targeting transcription factor irf3 PMID 38739631
Mesenchymal stem cell
Discovery and mechanism studies of a novel ATG4B inhibitor Ebselen by drug repurposing and its anti
trans
NDC 1308 1227511
PSB
Inhbb
The Role of MAPK Pathways in Airborne Fine Particulate Matter
DSC
ML291 (Standard)
caraway
ZNF436 Human Pre
Cleavage of HDAC6 to dampen its antiviral activity by nsp5 is a common strategy of swine enteric coronaviruses PMID 38289103
CK 571
Annexin
5
KOR agonist7
CCT
Mg
TG
OXS007417
human IL
HP1 cells
Anticandidal activities of terconazole, a broad
KDM2/7
Tetraplatin
Gasdermin D
Epha10
skin explants
Mnk1/2
Chac1 Rat Pre
ERD308
MEK
Prosapogenin CP
Comparison of 18F
Ren
Polysucrose 70
Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway PMID 24980819
New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid PMID 24332653
rough ER
CD6 蛋白, Cynomolgus (Biotinylated, HEK293, His
Phosphatase
Mag
Cobiprostone
Human IL18 mRNA
Semastatin 5A.2
Boc
Fat1
LP 471756
CCT
Seitomycin 630391
3
Cefditoren
LP10
Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer PMID 36034876
eurycomanol
hypoactivity
Structural characteristics and structure
TPGS
Adipocyte
Antileishmanial agent
Nicotinamide mononucleotide improves the ovarian reserve of POI by inhibiting NLRP3
Integrating larval zebrafish model and network pharmacology for screening and identification of edible herbs with therapeutic potential for MAFLD A promising drug Smilax glabra Roxb PMID 39406145
Blockade of MMP14 activity in murine breast carcinomas implications for macrophages, vessels, and radiotherapy PMID 25710962
Combined use of vitamin C and antifolates induces cuproptosis
Antileishmanial agent
Cell Proliferation Is Strongly Associated with the Treatment Conditions of an ER Stress Inducer New Anti
Jasmonic acid alleviates cadmium toxicity through regulating the antioxidant response and enhancing the chelation of cadmium in rice (Oryza sativa L.) PMID 35367286
Glaesserella parasuis serotype 5 promotes pyroptosis via degrading Caveolin
K2FeO4
Novel anti
Piezo1 channel activation stimulates ATP production through enhancing mitochondrial respiration and glycolysis in vascular endothelial cells PMID 36740831
The protective role of HMGB1 in affecting the balance between autophagy and pyroptosis to maintain neutrophils homeostasis during β
Metabolism differences of biofilm and planktonic Pseudomonas aeruginosa in viable but nonculturable state induced by chlorine stress PMID 35093368
LncRNA MALAT 1 Regulates miR
Synergy and Mechanism of Leflunomide Plus Fluconazole Against Resistant Candida albicans An in vitro Study PMID 37396066
R6238
Metformin Alleviates Sepsis
Rigidity versus Flexibility Is This an Issue in σ1 Receptor Ligand Affinity and Activity? PMID 27156565
Static magnetic field contributes to osteogenic differentiation of hPDLSCs through the H19/Wnt/β
DX
Loss of Myo19 increases metastasis by enhancing microenvironmental ROS gradient and chemotaxis PMID 38279020
PINK1 suppresses malignant phenotypes in esophageal squamous cell carcinoma PMID 40490793
Ganetespib in Epidermal Growth Factor Receptor
In
Intermittent Hypoxia Promotes TAM
Investigation of the synergistic effects of haloperidol combined with Calculus Bovis Sativus in treating MK
Heparin
TMT
Persistent luminescence phosphor as in
Glutaminolysis inhibition boosts photodynamic therapy to eliminate cancer stem cells PMID 38310827
Antioxidant and anti
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress
The interaction of GRP78 and Zika virus E and NS1 proteins occurs in a chaperone
Hypoxia
Copper Increases the Sensitivity of Cholangiocarcinoma Cells to Tripterine by Inhibiting TMX2
Milk
STA
A novel stoploss mutation CYB5R3 c.906A G(p.*302Trpext*42) involved in the pathogenesis of hereditary methemoglobinemia PMID 39154701
Melatonin Positively Regulates Both Dark
A Dual
Administration of 2
Frameshift variants in C10orf71 cause dilated cardiomyopathy in human, mouse, and organoid models PMID 38950288
Producing anti
HET0016 339068
HDM
FAM3B activates hepatic stellate cells to accelerate hepatic fibrosis by promoting glucose metabolism PMID 41027184
HL60
BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity PMID 28591720
Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors PMID 15490334
Metabolite of ellagitannins, urolithin A induces autophagy and inhibits metastasis in human sw620 colorectal cancer cells PMID 28976622
CDD
Preventive effect of D
Endoplasmic reticulum stress related super
Sibiricaxanthone A 241125
Acute oral intake of a higenamine
An orally bioavailable Chk1 inhibitor, CCT244747, sensitizes bladder and head and neck cancer cell lines to radiation PMID 28131548
CP
N
Establishment of bovine extraembryonic endoderm stem cells enables efficient blastoid formation PMID 40402743
A metabolite from commensal Candida albicans enhances the bactericidal activity of macrophages and protects against sepsis PMID 37553429
4
UAB116 3031463
Kirrel3 Rat Pre
WDR81 Human Pre
pre
Dusp18
Lum
亚精胺/精胺 N1
TOLLIP
WRN 解旋酶相互作用蛋白 1（WRNIP1）基因
IFI44L as a novel epigenetic silencing tumor suppressor promotes apoptosis through JAK/STAT1 pathway during lung carcinogenesis PMID 36584854
Hpn
SET 结合蛋白 1（SETBP1）基因
138311
170626
fluorogenic peptide
Mal
V
VLS 1272
5
Synthesis, characterization, and bioactivity of selenium nanoparticles stabilized by regenerated chitin nanofibers PMID 40187449
Discovery of Rigid Linker
Fenbenicillin potassium 1177
Ambenoxan hydrochloride 1617
P08
Herpes simplex virus 1 accelerates the progression of Alzheimer's disease by modulating microglial phagocytosis and activating NLRP3 pathway PMID 39026249
baicalensis
mmu
Dose
Enhanced topoisomerase II
Sarizotan dihydrochloride 177976
Inhibitory effect of hemicholinium
Mechanism of activation for the sirtuin 6 protein deacylase PMID 31822559
P
SPANXC Human Pre
HA/Hemagglutinin 蛋白, H1N1 (ABP49481, sf9, His)
SWI/SNF 相关、基质相关、肌动蛋白依赖性染色质调节因子，d 亚科，成员 1（SMARCD1）基因
Nintedanib Ameliorates Bleomycin
(
上皮剪接调节蛋白 1（ESRP1）基因
着丝粒蛋白 V（CENPV）基因
含 THAP 域 3（THAP3）基因
Amine
Glabrol, an acyl
Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells PMID 35326237
RAB21 controls autophagy and cellular energy homeostasis by regulating retromer
CS
Design, synthesis, and biological activity evaluation of new tankyrase
CSRP3
Fludioxonil, a phenylpyrrol pesticide, induces Cytoskeleton disruption, DNA damage and apoptosis via oxidative stress on rat glioma cells PMID 36228901
Resveratrol can induce differentiating phenotypes in canine oral mucosal melanoma cells PMID 37225449
Hhip
Efficacy of the novel selective platelet
Inhibiting NLRP3 enhances cellular autophagy induced by outer membrane vesicles from Pseudomonas aeruginosa PMID 39873509
3,4
SP2509 1423715
Adolescent cetylpyridinium chloride exposure impairs homologous recombination repair and induces granulosa cell apoptosis and follicular atresia via FOXM1/CREBBP complex suppression PMID 40239548
Activation of Na+/K(+)
Neb
Fluoranthene
Receptor binding profiles of KB
Design and synthesis of 11α
Rovazolac 1454288
Lipoprotein Lipase, Bovine
Repurposing Etalocib suppresses multidrug
EGCG
MST312
Repurposing potential of 1st generation H1
Accumulation of catechins and expression of catechin synthetic genes in Camellia sinensis at different developmental stages PMID 28597441
Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp Campsomeriella annulata annulata PMID 34941722
TLR7 agonist 28 1801518
Exploring 2
Btrc
LINCOMYCIN A NEW ANTIBIOTIC ACTIVE AGAINST STAPHYLOCOCCI AND OTHER GRAM
Verapamil, and its metabolite norverapamil, inhibit macrophage
The JAK2/STAT3 pathway is involved in the anti
亨廷顿相互作用蛋白 1（HIP1）基因
含 pleckstrin 同源性和 RhoGEF 结构域 G6（PLEKHG6）基因
同源框 C8（HOXC8）基因
束缚和伸长蛋白 zeta 2（FEZ2）基因
The caspase inhibitor IDN
Protein@Inorganic Nanodumpling System for High
NO
Measles and Nipah virus assembly Specific lipid binding drives matrix polymerization PMID 35857835
Peroxisome proliferator
Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability PMID 23897821
Downregulation of vdac2 inhibits spermatogenesis via JNK and P53 signalling in mice exposed to cadmium PMID 32199951
Structure
Disuccinimidyl suberate Crosslinker 68528
Development of Novel AKR1C3 Inhibitors as New Potential Treatment for Castration
Protective role of l
Gpha2 Mouse Pre
Single Nucleotide Polymorphisms in the Melanocortin His
Improvement of corneal barrier function by the P2Y(2) agonist INS365 in a rat dry eye model PMID 11133853
Distinct roles of prostaglandin D2 receptors in chronic skin inflammation PMID 21943706
Gnetol as a potent tyrosinase inhibitor from genus Gnetum PMID 12723623
Angustin A
P 08
Synergistic Effects of Glutamine Deprivation and Metformin in Acute Myeloid Leukemia PMID 39096478
Glutamine Metabolism Targeting Liposomes for Synergistic Chemosensitization and Starvation Therapy in Ovarian Cancer PMID 36596434
Gnetol 86361
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer PMID 27559084
Metabolomics analysis revealed the neuroprotective role of 2
SPANXD Human Pre
Do
A diketopiperazine fragment of human serum albumin modulates T
FCRL6 Human Pre
JAK3
2'
I
Pank3 Mouse Pre
Caspase
Circadian rhythm disturbance impairs intestinal mucus barrier and immune microenvironment via sebacic acid
Combretol 5084
3,4,5
Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma PMID 29235570
Mechanism of Curcumol Targeting the OTUB1/TGFBI Ubiquitination Pathway in the Inhibition of Angiogenesis in Colon Cancer PMID 40430059
2,5
Decanoyl
Linoleic acid derivatives target miR
An H
Cytochrome P450 4A isoform inhibitory profile of N
Citrus limon extract 84929
MS 222
Discovery of novel inhibitors of LEDGF/p75
Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitors PMID 33664846
Curcumenol
ZNRF2 Human Pre
Platycodin D2 66663
The Role of Interleukin
grass
Pank1 Mouse Pre
KT2
Azido sphingosine (d18 1) 3056013
连环蛋白β样 1（CTNNBL1）基因
Thymidine
84914
血管动蛋白（AMOT）基因
含泛素样结构域 CTD 磷酸酶 1（UBLCP1）基因
TRAF 相互作用蛋白（TRAIP）基因
161145
118472
Manipulating Adult Neural Stem and Progenitor Cells with G
Azido
TNKS
CI 686
(E/Z)
7
Real
Evidence that the lichen
Dried blood spot analysis without dilution Application to the LC
Dextran 500 Improves Recovery of Inflammatory Markers An In Vitro Microdialysis Study PMID 31298609
MCE
Histone methyltransferase SUV39H2 regulates apoptosis and chemosensitivity in prostate cancer through AKT/FOXO signaling pathway PMID 38170382
L
YM
PDCD6 Human Pre
Chemical constituents of Garcinia fusca structure elucidation of eight new xanthones and their cancer chemopreventive activity PMID 12608849
ZED1227
Sodium 2
Discovery of Three New Phytotoxins from the Fungus Aspergillus nidulans by Pathway Inactivation PMID 30708999
Idalopirdine 467459
Design and Synthesis of Pyrazoline Inhibitors of SARS
Inhbb Mouse Pre
OH
HBD Human Pre
Fluostatin B 158906
A 5
CD11b deficiency attenuates the ischemia/reperfusion
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