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Telomerase inhibitor MST
Preliminary risk
Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape PMID 40789922
CFP1 promotes germinal center affinity maturation and restrains memory B cell differentiation through H3K4me3 modulation PMID 40866336
POU5F1 promotes the proliferation, migration, and invasion of gastric cancer cells by reducing the ubiquitination level of TRAF6 PMID 38062041
Benzyl
4,4′
Microsomal aminopeptidase, Microorganism 9054
Synthesis, characterization, cytotoxicity and antibacterial activity of an anthracenyl
22 6 PS sodium 474943
硫化双氯酚
Dietary Cholest
AL
EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer PMID 40329096
胡黄连苷A
CDC801
Drug testing in blood validated negative
Thiamine pyrophosphate tetrahydrate
Empagliflozin and Dapagliflozin Reduce ROS Generation and Restore NO Bioavailability in Tumor Necrosis Factor α
The promigratory activity of the matricellular protein galectin
IL‑21/IL‑21R inhibit tumor growth and invasion in non‑small cell lung cancer cells via suppressing Wnt/β‑catenin signaling and PD‑L1 expression PMID 31573051
Inhibitors of the lipoxygenase pathway specifically block orthopoxvirus replication PMID 1898625
D
Fzd10 Rat Pre
Farrerol 4& 039;,7
Inhibitory effects of carbocisteine on type A seasonal influenza virus infection in human airway epithelial cells PMID 20543005
Plantaricin A reverses resistance to ciprofloxacin of multidrug
EG01377 2227996
MCE
Ro 04
MCE
[1,1′ 4′,1′′
Ethyl tetradecanoate
(S)
Thrombin
METTL1
vascular endothelial growth factor receptor
Cloning of the human IL
Tricyclic HIV integrase inhibitors potent and orally bioavailable C5
Conjugated linoleic acid
Horseradish peroxidase a modern view of a classic enzyme PMID 14751298
5'
Integration of network pharmacology, transcriptomics, and experimental verification to investigate the mechanism of action of cepharanthine hydrochloride against prostate cancer PMID 40413339
Spen Mouse Pre
4,4′
Impact of meropenem in combination with tobramycin in a murine model of Pseudomonas aeruginosa pneumonia PMID 23571540
MCE
AMP
The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosis PMID 37559097
Structure of acetylcholinesterase complexed with (
Analysis of the uptake of the fluorescent marker 2',7'
Biochemical basis of the effect of chondroitin sulphate on osteoarthritis articular tissues PMID 17644553
FXR Regulates Intestinal Cancer Stem Cell Proliferation PMID 30794774
ABHD17 regulation of plasma membrane palmitoylation and N
Mivebresib synergized with PZ703b, a novel Bcl
Cancer immunotherapy beyond immune checkpoint inhibitors PMID 29329556
Estrogen
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension
Alkyne
Metabolism of the cardioprotective agents dexrazoxane (ICRF
Beta
WAY
A novel selective mitochondrial
kappaB 激酶 ε 抑制因子（Ikbke）基因
Activation of neuropeptide Y1 and neuropeptide Y2 receptors by substituted and truncated neuropeptide Y analogs identification of signal epitopes PMID 8467862
Inhaled PAMAM
HL 725, an extremely potent inhibitor of platelet phosphodiesterase and induced platelet aggregation in vitro PMID 6294426
Molecular Cloning, Characterization, and Nutritional Regulation of Elovl6 in Large Yellow Croaker ( Larimichthys crocea) PMID 30979053
Difethialone 104653
LE135 155877
A new negative allosteric modulator, AP14145, for the study of small conductance calcium
4
4'
Microbial transformation of 20(S)
MCE
UBE2T Human Pre
Ceforanide in vitro and clinical evaluation PMID 507795
CCL17 exerts neuroprotection through activation of CCR4/mTORC2 axis in microglia after subarachnoid haemorrhage in rats PMID 35882433
Synthesis of cytotoxically active derivatives based on alkylated 2,3
The role of ancient ubiquitous protein 1 (Aup1) in regulating hepatic lipid droplet levels, endoplasmic reticulum stress, and inflammation in zebrafish (Danio rerio) PMID 40484276
112970
Cpa2
Tauromustine 85977
IT1t dihydrochloride (Standard)
Impact of Aerobic Training on Transcriptomic Changes in Skeletal Muscle of Rats with Cardiac Cachexia PMID 40650303
Cytokines in clinical cancer immunotherapy PMID 30413827
Amino acid substitutions in the fusion protein of respiratory syncytial virus in Fukushima, Japan during 2008
Methyl 6
Necroptosis blockade prevents lung injury in severe influenza PMID 38600381
N
Effects of salt
HSV
Characterization of simvastatin acid uptake by organic anion transporting polypeptide 3A1 (OATP3A1) and influence of drug
Oroxin B improves metabolic
Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells PMID 25548170
The p38 MAPK inhibitor, PD169316, inhibits transforming growth factor beta
Sesaminol prevents Parkinson's disease by activating the Nrf2
Potassium perfluorohexanesulfonate 3871
CD28 蛋白, Rat (HEK293, His)
Aquaporin 3 maintains the stemness of CD133+ hepatocellular carcinoma cells by activating STAT3 PMID 31197130
Iron
The PD
Inhibition of PI3K/Akt/NF
PCSK9 蛋白, Mouse (Biotinylated, HEK293, His
Arterolane 664338
MEIS2 抗体 (YA1778)（MEIS2 Antibody (YA1778)）
2
A portable and chromogenic enzyme
Cyclic GMP
Pxn
Estetrol
Identification of Ezetimibe and Pranlukast as Pharmacological Chaperones for the Treatment of the Rare Disease Mucopolysaccharidosis Type IVA PMID 31188588
FATE1 A cancer testis antigen with oncogenic functions
Elevated serum levels of stromal
A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation PMID 17496165
Pharmacologic suppression of inflammation by a diphenyldifluoroketone, EF24, in a rat model of fixed
CXCR2 perturbation promotes Staphylococcus aureus implant
Oleanolic acid inhibits M2 macrophage polarization and potentiates anti
Highly expressed VGLL3 in keloid fibroblasts promotes glycolysis and collagen production via the activation of Wnt/β
Molecular mechanisms of toxic effects of fotemustine in rat hepatocytes and subcellular rat liver fractions PMID 8625482
Hollow mesoporous organosilica nanoparticles reduced graphene oxide based nanosystem for multimodal image
Glycosaminoglycans modulate inflammation and apoptosis in LPS
Hexyl chlorocarbonate
Discovery of MK
Array
C
Discovering a new analogue of thalidomide which may be used as a potent modulator of TNF
Use of Perindopril Arginine/Indapamide/Amlodipine in the Management of Hypertension in Two Sub
GSK
MiRNA
胰高血糖素受体（Gcgr）基因
Inhbe Rat Pre
(
Discovery of Small Molecules that Bind to Son of Sevenless 2 (SOS2) PMID 39818983
12(Z)
Noraramtide
Boc
Napsagatran
LML134 1542135
2'
MCE
Baicalein specifically suppresses microsatellite instability colorectal cancer by targeting adenosylhomocysteinase to inhibit histone H3 lysine 4 trimethylation
Rat colitis
Pilaralisib
Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals PMID 20646191
RBM15 promotes COAD progression by regulating the m6A modification of TMC5 PMID 40883807
Molecular hybridization
Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives PMID 23566520
MS7829 3060519
FoxA2 抗体 (YA4863)（FoxA2 Antibody (YA4863)）
RHOV Human Pre
Wnt Inhibition Sensitizes PD
AS
Serum deprivation
S
5
Liver
安西他滨盐酸盐
SAR407899 hydrochloride 923262
2
Small
A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido
Ribonuclease T2 (animal free) (核糖核酸酶T2 (无动物源))
Adoprazine 222551
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor PMID 35136042
PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINS PMID 14166766
ClpP modulator 1
SR cells
Imatinib impurity 2 1987905
Betulinic acid derivative
ACPK 1304056
Benzofuran
Anti
PPA
decarboxylase
4
Mitochondrial fumarate inhibits Parkin
Candicidin
Clerodenoside A
Iadademstat 1431304
Bosutinib isomer 1391063
LAMP5 modulates IRF4 stability and nuclear transport a critical mechanism in myeloma progression and therapy PMID 40721659
m
Docking and database screening identify manidipine as a potential modulator of matrix metalloproteinase
[The effect of phosphodiesterase type 3 inhibitor on chorio
PPAR gamma 抗体 (YA122)（PPAR gamma Antibody (YA122)）
S297995
WF 3681
Estrogenic and transgenerational effects of perfluorocarboxylic acids through estrogen
S
Aldox
NA
Naphthalene
Brigimadlin intermediate1
Dd2 strain
Orally Bioavailable Enzymatic Inhibitor of CD38, MK
Discovery of (3
PSAT1 promotes autophagy to resist insufficient autophagy caused by cigarette smoke extract in human airway epithelial cells PMID 37832835
Ameliorative Effects of the Sesquiterpenoid Valerenic Acid on Oxidative Stress Induced in HepG2 Cells after Exposure to the Fungicide Benomyl PMID 34066673
4
Macrolide Inspired Macrocycles as Modulators of the IL
Nelfinavir 159989
Phyllanthusiin C 142674
protein imaging
Diselenide
JO 1784
Platelets promote invasion and induce epithelial to mesenchymal transition in ovarian cancer cells by TGF
ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3
Repositioning of the β
Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses PMID 26260341
Impaired learning and memory generated by hyperthyroidism is rescued by restoration of AMPA and NMDA receptors function PMID 35777536
Comprehensive analysis of heat shock proteins in glioma revealed the association with glioma
AZ8010
BCN
Targeting interferon regulatory factor 7 alleviates renal fibrosis by inhibiting macrophage
WR 99210
Discovery of Risdiplam, a Selective Survival of Motor Neuron
BIMAX2 1105053
Tomivosertib hydrochloride 1849590
Extended therapeutic window of a novel peptide inhibitor of TRPM2 channels following focal cerebral ischemia PMID 27317297
The antipsychotic drug chlorpromazine inhibits HERG potassium channels PMID 12788816
Semaglutide attenuates Alzheimer's disease model progression by targeting microglial NLRP3 inflammasome
Boc
SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53 PMID 37770925
Inhibition of p300 Increases Cytotoxicity of Cisplatin in Pancreatic Cancer Cells PMID 37666373
Anti
CFZ533
spiroindoline derivative
Ercalcitriol
FTO
Remodels the Immunosuppressive Tumor Microenvironment by Combination of Bacillus Calmette
TL033 2356230
Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2) PMID 34606270
Gemifloxacin a new fluoroquinolone approved for treatment of respiratory infections PMID 15187209
Protective effect of zinc gluconate on intestinal mucosal barrier injury in antibiotics and LPS
A Thermostable mRNA Vaccine against COVID
A Genome
DPM
Early IL
Gastrodin ameliorates postoperative cognitive dysfunction in aged mice by promoting nuclear translocation of Nrf2 through activation of AMPK PMID 37806469
Chronic Exposure to SCO
The structure of the GM
cis
The cytotoxicity of the anticancer drug elesclomol is due to oxidative stress indirectly mediated through its complex with Cu(II) PMID 24798374
R
TAS4464 hydrochloride 1848959
BL
Egln3 Rat Pre
MCE
2’
Glucagons
TCO
Telitacicept 2136630
Antibacterial properties of phenothiazine derivatives against multidrug
CXC chemokines in angiogenesis PMID 16046180
Uba52 Rat Pre
Inhibition of TGF
mGluR2 modulator 5 1639898
Distribution of the phosphatidylinositol 3
p53 Suppresses Metabolic Stress
Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages PMID 17915259
Oryzoxymycin
VX
Enopeptin A
Tyrosinase inhibitory constituents from the roots of Morus nigra a structure
Identification of common predictive markers of in vitro response to the Mek inhibitor selumetinib (AZD6244; ARRY
Benzohydroxamic acids as potent and selective anti
PTEN is both an activator and a substrate of chaperone
ATWLPPRAANLLMAAS 1228447
Characterization of Angiotensin
black spot
Oppenauer,
Adrixetinib
Phase I dose
NOL9 Human Pre
SPRED1 Interferes with K
Cbl 原癌基因 C（CBLC）基因
Leucomycin; a new antibiotic PMID 13595103
N
Tnk1/Kos1 a novel tumor suppressor PMID 20697568
Essential role of microglial transforming growth factor
Nimesulide
PPI1019
DCLK1
TK216
B Lymphocytes in Multiple Sclerosis Bregs and BTLA/CD272 Expressing
HDL cholesterol
The design and synthesis of diaryl ether second generation HIV
Ginsenoside F2
Rescue of Mutant CFTR Channel Activity by Investigational Co
Inhibition of DNA methyltransferase aberrations reinstates antioxidant aging suppressors and ameliorates renal aging PMID 34874096
Activation of WNK1 signaling through Piezo1 PMID 40880539
Vegfd Rat Pre
LCQ
Sunscreen filter octocrylene is a potential obesogen by acting as a PPARγ partial agonist PMID 34864131
Usp25 Rat Pre
Aβ
IPS
PTPRC/CD45R0 蛋白, Human (HEK293, His)
RP 73401
P2Y12, a new platelet ADP receptor, target of clopidogrel PMID 15199474
Determining the necessity of phenyl ring π
MAPK4 Human Pre
BAPTA
ABT492
MK0791
Essential role of Gas6 for glomerular injury in nephrotoxic nephritis PMID 12122116
Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons PMID 10627576
Synergistic enhancement of skin permeability by N
Scattering
A novel class of small molecule inhibitors of Hsp90 PMID 18785742
Blockade of Discoidin Domain Receptor 2 as a Strategy for Reducing Inflammation and Joint Destruction in Rheumatoid Arthritis Via Altered Interleukin
CRBN ligand
SIRT
Phalloidin
PCI29732, a Bruton's Tyrosine Kinase Inhibitor, Enhanced the Efficacy of Conventional Chemotherapeutic Agents in ABCG2
Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models PMID 35797217
Synthesis of dihydropyrimidine α,γ
N4
PROTAC SMARCA2/4
PF
Jesaconitine
D
Pb
immature seed
Mag
BAT 6021
β
GW 6471
Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells PMID 23270663
Antitumor agent
Lobetyolinin
PF00277343
Officinaruminane B 1246282
Identification of a new chemical class of potent angiogenesis inhibitors based on conformational considerations and database searching PMID 12941313
BI
Catabolism of GABA, succinic semialdehyde or gamma
Tungstosilicic acid hydrate
Abrilumab 1342290
Lasalocid induces cytotoxic apoptosis and cytoprotective autophagy through reactive oxygen species in human prostate cancer PC
Methyl 6
同源框 B5（HOXB5）基因
Duocarmycin GA 1613286
BAY 728
PHD2 抗体 (YA2431)（PHD2 Antibody (YA2431)）
TNS3 Human Pre
Rebaudioside I 1220616
XL
EU5346
Novel curcumin derivative CNB
LYG
SR
Ingenol disoxate 1383547
Discovery of novel 1,2,3,4
AS
The contribution of spinal dorsal horn astrocytes in neuropathic pain at the early stage of EAE PMID 36332813
longiflorum
FC11409B 1380411
Cefacetrile 10206
The detergent Triton X
Sono
HDAC6
Ak9 Mouse Pre
BCTC (Standard)
UBP
K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells PMID 19351824
Schiarisanrin A 130252
Effects of YM905, a novel muscarinic M3
THP
Erythrina Cristagalli Lectin (Fluorescein) (ECL (Fluorescein))
EMD61753
HIV
Ehd4
24
Trilysine 13184
[Determination of partition coefficient by high
Suppressive effect of verproside isolated from Pseudolysimachion longifolium on airway inflammation in a mouse model of allergic asthma PMID 16644484
Bis
Metronomic doxifluridine chemotherapy combined with the anti
BXL
The role of the poly(A) binding protein
Laropiprant sodium 572874
Quinidine polygalacturonate
QY
NNI 0001
Ezetimibe
GW 117
Leu
CTLA
Donasine
5,5'
4
DAM
ACVR2B/Fc counteracts chemotherapy
5
EAI 045
BAY3389934
Comparative inhibitory profile and distribution of bacterial PARPs, using Clostridioides difficile CD160 PARP as a model PMID 29795234
CEP55 Promotes Acral Melanoma Progression via MAPK Pathway and Predicts Survival Following Immunotherapy PMID 40918457
mGluR5 modulator 1 1261171
Anti
TDRL
3
LT
Demcizumab 1243262
Sitsirikin
A Potent and Selective Kallikrein
CSF1R
Bradycardic and proarrhythmic properties of sinus node inhibitors PMID 16387796
Discovery of novel pyrimidine and malonamide derivatives as TGR5 agonists PMID 25082126
TAK
MCE
Mitotic Arrest Deficient 2 Like 1 Contributes to Colorectal Cancer Cell Migration, Invasion, and Oxaliplatin Resistance Through the Wnt/β
Methionyl
Neuron specific enolase a promising therapeutic target in acute spinal cord injury PMID 26847611
AP521 151227
TRC051384 hydrochloride 1333327
Induction of necrosis in human liver tumor cells by α
K48
Autophagy Improves Inflammatory Response in Sepsis Accompanied by Changes in Gut Microbiota PMID 39465181
KRN633 A selective inhibitor of vascular endothelial growth factor receptor
Fmoc
Tubulin/MMP
Polymerase theta inhibition impairs tumor growth and amplifies melphalan
An investigation of the possible precursors of urinary pregnanetriol PMID 13700983
IN/Ku70 complex
HIV
4
Glu(EDANS)
Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid PMID 31677446
Compartmentalisation of Hepatitis B virus X gene evolution in hepatocellular carcinoma microenvironment and the genotype
The Biological and Biomechanical Role of Transglutaminase
Characterizing CDK8/19 Inhibitors through a NFκB
The stable cyclic adenosine monophosphate analogue, dibutyryl cyclo
Practical synthesis of a phthalimide
Pdk3
New, potent, selective, and short
Specific multivalent molecules boost CRISPR
Curcumol may alleviate psoriasis
Saussureamine C 148245
Dpep2 Rat Pre
Engineered E. coli OMVs Carrying the Membrane
HGF a multifunctional growth factor controlling cell scattering PMID 10641789
Brofaromine hydrochloride 63638
MCE
Synthesis and in vivo SAR study of indolin
1
Blocking mast cell
Depsidones from Lichens as Natural Product Inhibitors of M
Thermodynamic profiles of the interactions of suramin, chondroitin sulfate, and pentosan polysulfate with the inhibitory domain of TIMP
MCE
HIF
L
ALCAM/CD166 蛋白, Cynomolgus (HEK293, Fc)
Pioglitazone potassium 1266523
A new coumarin from the stem of Angelica dahurica PMID 11885692
EIF1B 蛋白, Human (His)
Daxalipram
Osteoblast
ARV393
Desmethylazelastine
TRPV4
A new exploration of licorice metabolome PMID 27979300
FR
(±)
Pharmacological profile of MEN91507, a new CysLT(1) receptor antagonist PMID 12242094
Chlorfenapyr
RALBP1 Human Pre
CPN 351
Proper RPA acetylation promotes accurate DNA replication and repair PMID 37140030
Discovery of a novel CD39 inhibitor by DNA
Total synthesis of the bicyclic depsipeptide HDAC inhibitors spiruchostatins A and B, 5''
ATM inhibition exploits checkpoint defects and ATM
L670630
Chondroitinase ABC II (软骨素ABC外切酶)
Clathrin
MitoEbselen
1
A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3
Development and validation of pharmacokinetics assays for a novel HER2
Anticancer activity of protocatechualdehyde in human breast cancer cells PMID 24712725
Sialic acids promote macrophage M1 polarization and atherosclerosis by upregulating ROS and autophagy blockage PMID 37270929
MCE
Antioxidant and in vitro anticancer effect of 2
Modeling Extraordinary Response Through Targeting Secondary Alterations in Fusion
GS 0393
The anxiolytic effects of a Valerian extract is based on valerenic acid PMID 25066015
Synthesis and Evaluation of 68Ga
AGFG1 Human Pre
ADI 65534
HHS 0701
MCE
LUBAC enables tumor
F 15845
Prostaglandins, catecholamines, and cardiovascular responses to hemorrhage PMID 7212088
PD 168077
Synthesis and evaluation of macrocyclic diarylether heptanoid natural products and their analogs PMID 22137846
IL
抑制素β亚基 B（INHBB）基因
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