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Donasine 1017237
Dimethyl phthalate damaged the cell membrane of Escherichia coli K12 PMID 31096126
Identification of glycolysis related pathways in pancreatic adenocarcinoma and liver hepatocellular carcinoma based on TCGA and GEO datasets PMID 33607990
Fenbufen
Discovery of new acylaminopyridines as GSK
Deficiency of gluconeogenic enzyme PCK1 promotes metabolic
ERK pathways
Hnrnpdl Mouse Pre
Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II PMID 25073716
Slc6a8
HA/Hemagglutinin 蛋白, H1N1 (ACQ63286, HEK293, His)
Myt1
Prkaa1 Mouse Pre
MTIC
D
Commiphora mukul extract
6,6',6''
L
Diethyl 2,5
[2,2'
4,4',4'',4'''
2,4,6
Luspatercept 1373715
Lanostane
Corticotropin
4
Eriochrome black T
Brentuximab 2088770
1
Spleen tyrosine kinase
Anticancer agent 34 2379335
Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells PMID 19226254
β
Inosine
MPL
4
Vitamin K 12001
Beta
Ephrin Receptor B3 抗体 (YA2877)(PBS only)(Ephrin Receptor B3 Antibody (YA2877)(PBS only))
Neurotoxin Inhibitor 951571
2
2
Canagliflozin impurity 3
Ginsenoside Rb1 Alleviated the AKI to CKD Transition by Targeting VEGFR2 PMID 40682486
MCE
Estrogen Inducible Protein pS2 抗体 (YA2377)(Estrogen Inducible Protein pS2 Antibody (YA2377))
TNFSF15 facilitates differentiation and polarization of macrophages toward M1 phenotype to inhibit tumor growth PMID 35127254
SD
J
beta 2 Microglobulin 抗体 (YA935)(beta 2 Microglobulin Antibody (YA935))
UK
Doubly loaded cycloSaligenyl
MDGN 002
JI130 2234271
red blood cells
DMT
U
Calcium phosphorylcholine
Amfenac
5,10,15,20
Bifunctional Nanostarch against Neuronal Apoptosis via Mitochondria Protection for Ameliorating Ischemic Stroke Injury and Promoting Long
Tetrakis(3
CRBN ligand
An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate PMID 17023534
Comparative effects of betamethasone, cyclosporin and nedocromil sodium in acute pulmonary inflammation and metalloproteinase activities in bronchoalveolar lavage fluid from mice exposed to lipopolysaccharide PMID 10419836
Benzyl
K134 189362
Iptacopan TFA 1644670
The PPARβ/CERK/C1P signaling pathway is a potential mechanism by which antimony exposure promotes prostate cancer cell proliferation PMID 40327927
Structure
PCN 224 1476810
Failure to Resolve Inflammation Contributes to Juvenile
Sertaconazole 99592
Vonifimod
3,3',4,4',5,5',6,6'
Design, synthesis and antitubercular activity of novel N
IRAK4
YAP as a potential therapeutic target for myofibroblast formation in asthma PMID 39939959
Seven new 2
A diverse induction of apoptosis by trabectedin in MCF
Activation of GCN2 in macrophages promotes white adipose tissue browning and lipolysis under leucine deprivation PMID 34004054
RecQ 样解旋酶 4(RECQL4)基因
TUBB2B Human Pre
Niflumic acid exhibits anti
Mal
Mal
RSPO4 Human Pre
Extracellular signal
4,4'
Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A
JAML/AMICA 蛋白, Human (HEK293, His)
Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate PMID 32574049
6
原小檗碱类化合物 (Protoberberine Alkaloids)
Tecalcet Hydrochloride 177172
Long
Boc
p60c
RO5083945
Revealing CD38 cellular localization using a cell permeable, mechanism
Cecropin P1, porcine 125667
GABA A 型受体相关蛋白样 2(GABARAPL2)基因
Regulation of histone H3K4 tri
Polymer
Altenuene 29752
4
Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages PMID 32112870
Creb3 Mouse Pre
OFD1 Human Pre
Prometryn 7287
Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9
Suvemcitug 1610010
Sin3b Mouse Pre
Technical Support
Galanin message associated peptide (1
membrane integrity
MDL14514
hydrolytic enzyme
hsa
Cacna1d Rat Pre
polyamine analogue
Thio
VVZ
RO5323441
Salvianolic acid A inhibits PRRSV replication via binding to Keap1 to activate the MKRN1
JAK3 A573V and JAK3 M511I mutations in peripheral T
SIGLEC10 Human Pre
ZTA
HEK Blue
GS
Discovery of Novel PDEδ Autophagic Degraders A Case Study of Autophagy
ABO Human Pre
HU 345
Development of Novel Phthalazinone
Pak4
Antibacterial agent 308 3092564
MW
Histone lactylation promotes multidrug resistance in hepatocellular carcinoma by forming a positive feedback loop with PTEN PMID 39890782
Tris(3
Benzophenone synthase from cultured cells of Centaurium erythraea PMID 8925910
Scd
A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential PMID 22223752
KBP7072
A 924
Medetomidine
MBL
MCE
KWR
Tyr
Lymphangiogenesis
BMS394136
EBI031
CBR1
ABSK
chronic colitis
β
Probucol (Standard)
Fluor 488
CP597396
HIV
Lobucavir
Let
AMPK activator 7 1623138
Bishomoreserpine
YK11 1370003
Malaria
Telotristat
A
Mitoflaxone
Cy5.5 HA (MW 10000) (Cy5.5 标记 透明质酸 (MW 10000))
Lfcin B
R 547
Balsalazide
Deletion of PDK1 in oligodendrocyte lineage cells causes white matter abnormality and myelination defect in the central nervous system PMID 33276084
KER 050
Kaempferol Ameliorates Functional Constipation in Mice by Regulating Autophagy of Interstitial Cells of Cajal via the p53/AMPK/mTOR Axis PMID 41240265
Histone H3.3 抗体 (YA367)(Histone H3.3 Antibody (YA367))
atherothrombotic
AMBRA1 Human Pre
KEMPFPKYPVEP 1393589
Deoxycholic Acid
Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor
Enocyanin
9
NLRP3
Viscumneoside III 118985
Antitumor agent
Hsp90α
NADH dehydrogenases from basic science to biomedicine PMID 11695833
Protecting mitochondria via inhibiting VDAC1 oligomerization alleviates ferroptosis in acetaminophen
Anticancer agent 255 1983924
Study of adenylyl cyclase
Curcumin monoglucoside
BMS
MC 1568
Tetomilast 145739
MW
Siponimod 1230487
TGF
S 2846
Bimatoprost and its free acid are prostaglandin FP receptor agonists PMID 11740958
Heterogeneous nuclear ribonucleoprotein A2/B1 is a negative regulator of human breast cancer metastasis by maintaining the balance of multiple genes and pathways PMID 31901866
NEO
CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso
New Target for Minoxidil in the Treatment of Androgenetic Alopecia PMID 37645625
FK962 protects retinal ganglion cell under hypoxia/reoxygenation Possible involvement of glial cell line
U
RORA
IHCH7179
Propafenone
TNT
GPR84 agonist
Biological studies on formycin and formycin B PMID 5673295
Novel E
Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway PMID 29540668
Pde9a
BI
A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin PMID 36227980
Hyperwightin B
Win 18446
Effects of cularine and other isoquinoline alkaloids on guinea
1
NSC 103055
Med12 Rat Pre
Lenumlostat
Mis
IL
Chikusetsusaponin IVa targeted YAP as an inhibitor to attenuate liver fibrosis and hepatic stellate cell activation PMID 40098188
Influence of Bisphenol Compounds at Nanomolar Concentrations on Chromosome Damage Induced by Metabolically Activated Carcinogens in HepG2 Cells PMID 34241998
Xihuang pill ameliorates colitis in mice by improving mucosal barrier injury and inhibiting inflammatory cell filtration through network regulation PMID 37640256
ERO1α
Regeneration of taste through sonic hedgehog upregulation by photobiomodulation PMID 37483112
JNJ627
Anticancer and Reversing Multidrug Resistance Activities of Natural Isoquinoline Alkaloids and their Structure
Glucosamine 6
Inhibitory effect of 10
FR144633
Klf3 Mouse Pre
Hexadecanedionic acid
Iso cephalomannine 173101
MCE
Thalidomide
PDL 063
Altenuene
ZG
Ethybenztropine hydrochloride (Ponalid hydrochloride)
FGFR4
PDE2A
resiniferatoxin
XL041 1256918
Evodiamine inhibits NLRP3 inflammasome
GEN 3014
Kifc3
Neolignans from the Arils of Myristica fragrans as Potent Antagonists of CC Chemokine Receptor 3 PMID 27419473
AZD6482
Preclinical antitumor activity of the orally available heat shock protein 90 inhibitor NVP
Poricoic acid a ameliorates high glucose
<br/>
(S)
DA5
TA
The first trial of CIM331, a humanized antihuman interleukin
NN 8828
C18 Ceramide
Novel synthetic small
PBZ 1038
Boc
Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia PMID 8597956
Discovery of Novel Anti
Antibacterial agent 285 2797056
Direct Yellow 7
KLRC1
STING agonist
trans
alpha
ILK
Lefty A protein inhibits TGF
NEDD4L suppresses PD
CRBN ligand
MCE
HA
CASP3 activator 1
Norfluoxetine hydrochloride 57226
DSPE
CRBN ligand
Sulfamethizole
Casp7
DHRS2 mediates cell growth inhibition induced by Trichothecin in nasopharyngeal carcinoma PMID 31291971
BP Fluor 568 NHS ester 2227463
New monoclonal antibodies for the treatment of acute lymphoblastic leukemia PMID 27521873
CDD
叶酸水解酶 1(FOLH1)基因
Misoprostol acid
CP 751871
CCT367766 2229856
2
SPDP
TET2 regulates extranodal NK/T cell lymphoma progression through regulation of DNA methylation PMID 38979860
12
MCE
Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum PMID 28038325
CGI 560 845269
Clinical importance of long non‑coding RNA LINC00460 expression in EGFR‑mutant lung adenocarcinoma PMID 31789388
Sp5
SRPIN 803
WY
Stereo
KL
DNTTIP2 Human Pre
TGFβ1
TAK147
Butralin
Synthetic peptide analogues differentially alter the binding affinities of cyclic nucleotide dependent protein kinases for nucleotide substrates PMID 2837278
2'
Daxdilimab 2245966
DNASE1L3 Human Pre
VK 2809
NSC 71795
Benzodiazepine
OfChi
R 835
Nodosin
Prophylactic supplementation with selenium nanoparticles protects against foodborne toxin zearalenone
Rnf111
spirooxindole
MRE
Longestin
CHP2 Human Pre
4α
KT
H4R antagonist 1 1429375
Overexpressed
Structure
ODN1826
YGZ 331
membrane potential
Chebulic acid
Discovery of novel HCV polymerase inhibitors using pharmacophore
Ondansetron
cis
Nabumetone
FGF2
N
Huh
CEP
Metformin revert insulin
Discovery of a Potent and Selective in Vivo Probe (GNE
Antibody
Substituted penicillin amides. Duration of antibacterial activity (depot effect) in experimental infections in mice PMID 4628325
EGFR/VEGFR2
Moprolol 5741
DNA cleavage
PRAX944
MRT67307 hydrochloride 2095432
Folic Acid Functionalized AQ4N/Gd@PDA Nanoplatform with Real
CD4 T cell
ATR
Benzeneethanamine,2
Inhibition of Growth of Bladder Cancer Cells by 3
Inducing Synergistic DNA Damage by TRIP13 and PARP1 Inhibitors Provides a Potential Treatment for Hepatocellular Carcinoma PMID 35517402
ADP ribos
Activity and QSAR study of baogongteng A and its derivatives as muscarinic agonists PMID 16153841
PSMB9 Human Pre
BAL 0028
Ghrelin O
PAH hPASMC
S
Lepiochlorin
NSC
Bipolal 155112
ITF5924 2760854
Izenivetmab 2447755
metamorphosis
CK1δ
Ruboxistaurin
OptoBI 1
SCO
Induction of morphological changes in the urothelium of cultured adult rat bladder by sodium saccharin and sodium cyclamate PMID 2421938
FE
Dynamin 2 抗体 (YA4063)(Dynamin 2 Antibody (YA4063))
4
nAChR1
Relenopride
Structure
NSC
SC99 882290
Microbial metabolite drives ageing
Schisandrin B protect inner hair cells from cisplatin by inhibiting celluar oxidative stress and apoptosis PMID 38789064
Ritanserin suppresses acute myeloid leukemia by inhibiting DGKα to downregulate phospholipase D and the Jak
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha PMID 11980910
Discovery of a First
Down
Reactive Blue 4 as a Single Colorimetric Chemosensor for Sequential Determination of Multiple Analytes with Different Optical Responses in Aqueous Media Cu2+
The role of quercetin, flavonols and flavones in modulating inflammatory cell function PMID 20887269
血管内皮生长因子受体
H
Trametinib suppresses HIV
An oxygen
Emopamil
Synaptotagmin 1 and Synaptotagmin 7 promote MR1
Protective effect of sodium propionate in Aβ1
NVP
MCE
Control of Humoral Response in Renal Transplantation by Belatacept Depends on a Direct Effect on B Cells and Impaired T Follicular Helper
Hapten
SHP
Discovery of X10g as a selective PROTAC degrader of Hsp90α protein for treating breast cancer PMID 37619298
Alantolactone induces apoptosis in HepG2 cells through GSH depletion, inhibition of STAT3 activation, and mitochondrial dysfunction PMID 23533997
Tiagabine, SK&F 89976
Hydroxysafflor yellow A and anhydrosafflor yellow B alleviate ferroptosis and parthanatos in PC12 cells injured by OGD/R PMID 34923102
Excess filaggrin in keratinocytes is removed by extracellular vesicles to prevent premature death and this mechanism can be hijacked by Staphylococcus aureus in a TLR2
DNase II activated by the mitochondrial apoptotic pathway regulates RIP1
P2Y14 Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model PMID 32551012
Analysis of ecdysteroids by micellar electrokinetic chromatography with on
Synthesis and biological evaluation of 2
GDF5 reduces MMP13 expression in human chondrocytes via DKK1 mediated canonical Wnt signaling inhibition PMID 24561281
Cinoxacin mechanism of action, spectrum of activity, pharmacokinetics, adverse reactions, and therapeutic indications PMID 6763208
Supplementing the Diet with Sodium Propionate Suppresses the Severity of Viral Immuno
Exendin
Up
A Novel Small
Differential actions of L
CXCL16 蛋白, Canine (HEK293, His)
Design, Synthesis, and Biological Evaluation of a Series of Anthracene
12,13
Design and Synthesis of Dual
tert
cell mitosis
MK
XRF 1021
SMU
Raffinose
BF 168
Isolinderalactone
PJ 34
Curdlan activates dendritic cells through dectin
GR144053 trihydrochloride 1215333
TNP1 Human Pre
Mnk1 is required for angiotensin II
Corticosterone
Molecular determinants of AHPN (CD437)
Fazadinium
RO5461111 1252637
Increased RANKL expression is related to tumour migration and metastasis of renal cell carcinomas PMID 19455604
HIV
Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2
Isobavachin 31524
Novel antidepressant mechanism of hypericin Role of connexin 43
Strain Streptomyces sp. P
MAO
Single
Pentacosane
RRM1 抗体 (YA3899)(PBS only)(RRM1 Antibody (YA3899)(PBS only))
Mixed ligand complexes of benzimidazole and pyrimidine hydroxy azo dyes with some transition metals and glycine, dl
BMX 非受体酪氨酸激酶(Bmx)基因
Sarafloxacin
Inebilizumab, a B Cell
Augmenting the therapeutic efficacy of adenosine against pancreatic cancer by switching the Akt/p21
Caplacizumab a change in the paradigm of thrombotic thrombocytopenic purpura treatment PMID 31359806
Structure, function and inhibition of critical protein
Clinical usefulness of serum prostate specific antigen for the detection of prostate cancer is preserved in men receiving the dual 5alpha
Anti
3,6
Evaluation of the carcinogenic potential of insulin glargine (LANTUS) in rats and mice PMID 12055018
EphA4 regulates white matter remyelination after ischemic stroke through Ephexin
Diaporthein B
Anti
GNKG168
AMY
Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs PMID 29518158
sphenanthera
An in
Kynurenic acid as a ligand for orphan G protein
Identification of SQ609 as a lead compound from a library of dipiperidines PMID 21807506
Identification of a novel fibroblast growth factor receptor
Potent Rifampicin derivatives can clear MRSA infections at single low doses when concomitantly dosed with Vancomycin PMID 37872357
GBR 12935 fumarate 1349767
Almorexant hydrochloride 913358
Terlipressin protects intestinal epithelial cells against oxygen
Senolytic treatment to rescue hallmarks of senescence in lymph node fibroblasts from patients with rheumatoid arthritis Implications for premature aging and potential therapeutic intervention in early rheumatoid arthritis PMID 40336246
Danvatirsen
Diquinoxalino[2,3
Investigating the proliferative inhibition of HepG2 cells by exosome
CYP1B1 ligand 2 2836297
The structures of salt inducible kinase 3 in complex with pharmacological inhibitors reveal determinants for binding and selectivity PMID 38508313
Poncirin 14941
Salt
MCE
Identification of pharmacological inhibitors of the MEK5/ERK5 pathway PMID 18834865
Isolation of Tryptanthrin and Reassessment of Evidence for Its Isobaric Isostere Wrightiadione in Plants of the Wrightia Genus PMID 30295480
Berberine alleviates Alzheimer's disease by activating autophagy and inhibiting ferroptosis through the JNK
CAIX/CAXII
The nature of uncoupling by n
Mitochondrial GRIM19 Loss Induces Liver Fibrosis through NLRP3/IL33 Activation via Reactive Oxygen Species/NF
Umbilical cord mesenchymal stem cells promote neurological repair after traumatic brain injury through regulating Treg/Th17 balance PMID 34793756
Synthesis and biological evaluation of novel 1
An Immune Subtype Classification System Enables the Development of Strategies to Predict and Enhance Immunotherapy Responses in Colorectal Cancer PMID 39879113
Carboxypeptidase B1/CPB1 蛋白, Human (HEK293, His)
The AMPK
L
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