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Identification of the KIF and MCM protein families as novel targets for combination therapy with CDK4/6 inhibitors in bladder cancer PMID 36813612
Liposomal Extravasation and Accumulation in Tumors as Studied by Fluorescence Microscopy and Imaging Depend on the Fluorescent Label PMID 34197075
Inhibition of iron ion accumulation alleviates polystyrene nanoplastics
UNBS 3157
A novel phosphodiesterase inhibitor for the treatment of chronic liver injury and metabolic diseases PMID 38950389
MCE
ALDH1A1 Contributes to PARP Inhibitor Resistance via Enhancing DNA Repair in BRCA2
The effect of class
De
First
Sprengerinin C exerts anti
hsa
Iodinated benzimidazole PARP radiotracer for evaluating PARP1/2 expression in vitro and in vivo PMID 27689533
UNBS
Recent advances in the identification of gamma
A PRMT5
Bioprinted Fibroblast Mediated Heterogeneous Tumor Microenvironment for Studying Tumor
Secondary bile acid ursodeoxycholic acid alters weight, the gut microbiota, and the bile acid pool in conventional mice PMID 33600468
Comprehensive pan
β
Estrogen receptor α mediated M1/M2 macrophages polarization plays a critical role in NASH of female mice PMID 35114586
S100A8/A9 predicts response to PIM kinase and PD
Serine Biosynthesis Is a Metabolic Vulnerability in IDH2
HY
Modulation of protein S and growth arrest specific 6 protein signaling inhibits pancreatic cancer cell survival and proliferation PMID 32945517
NF
Elaboration and profiling of the first OSBP degrader issued from natural Schweinfurthins PMID 40884917
Species differences in the metabolism and excretion of sulphasomidine and sulphamethomidine PMID 4974221
Eldecalcitol induces apoptosis and autophagy in human osteosarcoma MG
Absorption, distribution, metabolism, and excretion of furosemide in dogs and monkeys I analytical methodology, metabolism, and urinary excretion PMID 824434
Comprehensive identification and characterization of in vitro and in vivo metabolites of the novel GLP
Safety of cefepime a new extended
Biomimetic Nanoparticles with Dual Targeting for Hepatocellular Carcinoma Promote Tumor Immune System Activation by Enhancing Extracellular ATP Homeostasis PMID 40745694
H3K27 Acetylation
Ambocin 108044
The protein kinase D1
Phthalazino[1,2
MIT
Mitochondrial transfer of drug
Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin
NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress PMID 40655016
CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5 PMID 26752644
Differential effects of GABA in modulating nociceptive vs. non
The association of erythromycin ethylsuccinate with acute colitis in horses in Sweden PMID 15338913
Nucleobindin
Melanocortin receptor agonists, penile erection, and sexual motivation human studies with Melanotan II PMID 11035391
Design, Synthesis, and Biological Evaluation of 2
Snailase, Snail gastrointestinal 158736
Mutation Ter462GlnextTer17 introduces a tail to C
Citalopram and Cannabidiol In Vitro and In Vivo Evidence of Pharmacokinetic Interactions Relevant to the Treatment of Anxiety Disorders in Young People PMID 34121064
Recombinant Human Serum Albumin(rHSA) (重组人血清白蛋白（rHSA）)
[Release of acetylcholine and its regulation] PMID 1382687
Comparison of predicted intrinsic hepatic clearance of 30 pharmaceuticals in canine and feline liver microsomes PMID 29405805
Dissecting the roles of DR4, DR5 and c
Short telomeres and high telomerase activity in T
CDCP1
Structure
hCAII
Inhibition of spastin impairs motor function recovery after spinal cord injury PMID 37918696
Danger
Discovery of a Highly Selective Sigma
Development of 2,2
Pibf1
CRBN ligand
Targeting Pim Kinases and DAPK3 to Control Hypertension PMID 30033129
PGAM5 抗体 (YA6701)（PGAM5 Antibody (YA6701)）
Recombinant human interleukin
Novel 5
Protein arginine methyltransferase expression and activity during myogenesis PMID 29208765
CD3 CD8 T
Erlotinib and Onalespib Lactate Focused on EGFR Exon 20 Insertion Non
CD39
Design and development of Isatin
Clinical and immunomodulatory effects of toceranib combined with low
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells PMID 33035517
The Effects of Sinapic Acid on the Development of Metabolic Disorders Induced by Estrogen Deficiency in Rats PMID 29967666
Boc
EGF
Identification of orally available naphthyridine protein kinase D inhibitors PMID 20684591
Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor
Alloimperatorin activates apoptosis, ferroptosis, and oxeiptosis to inhibit the growth and invasion of breast cancer cells in vitro PMID 35263194
Epithelial cell
Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev
Mid1ip1
t
( )
Carboxymethylcellulose encapsulated fingolimod, siRNA@ZnO hybrid nanocomposite as a new anti
Developing early formulations practice and perspective PMID 17658228
Rational design of 7
ETX0282 2209871
Characterization of 8
In vitro efficiency of 9
Ellagic acid inhibits cell proliferation, migration, and invasion in melanoma via EGFR pathway PMID 32509220
Effect of a novel 5
Crisaborole
LY2801653 is an orally bioavailable multi
Positive allosteric modulation of the mu
Non
Metformin (hydrochloride) 1115
Synthesis and anti
Gum Arabic Ameliorates Impaired Coagulation and Cardiotoxicity Induced by Water
L
Hydroxy
MCE
Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis PMID 33606974
Waglerin
Natural Alkaloid Compounds as Inhibitors for Alpha
TurboID
The synthesis of ursolic acid derivatives with cytotoxic activity and the investigation of their preliminary mechanism of action PMID 19091579
Ethyl Acetate Fraction of Zanthoxylum bungeanum Ameliorates Cognitive Deficit by Facilitating the PHGDH
Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR PMID 31112550
Discovery of (2,4
Bioactive Isoquinoline Alkaloids with Diverse Skeletons from Fissistigma polyanthum PMID 37615114
SLC6A19
Collagen
Statin administration or blocking PCSK9 alleviates airway hyperresponsiveness and lung fibrosis in high
PHGDH
The many roles of FAS receptor signaling in the immune system PMID 19239902
Ladiratuzumab vedotin 1629760
2'
5,5',5''
Decanoic acid
Four new stilbenoids from the lianas of Gnetum montanum f. megalocarpum PMID 14994195
Synthesis and biological evaluation of irreversible EGFR tyrosine kinase inhibitors containing pyrido[3,4
Photoactivation of mitochondrial reactive oxygen species
MKK4/MAP2K4
Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt
Discovery of SK
黄嘌呤氧化还原酶 (XOR)
Pellitorine protects chronic restraint stress
内皮素受体 A 型（EDNRA）基因
UBE3C promotes pancreatic ductal adenocarcinoma progression by catalysing p53 ubiquitination PMID 40553397
Mechanisms of methyclothiazide
Datura Stramonium Lectin (Fluorescein)
Fragment
3
Microglia LILRB4 upregulation reduces brain damage after acute ischemic stroke by limiting CD8+ T cell recruitment PMID 39217343
A micropeptide encoded by a putative long noncoding RNA regulates muscle performance PMID 25640239
Toxic effects of combined stressors on Daphnia pulex Interactions between diazinon, 4
Protein Arginine Methyltransferase 5 Promotes the Migration of AML Cells by Regulating the Expression of Leukocyte Immunoglobulin
Heteroarylnitrones as drugs for neurodegenerative diseases synthesis, neuroprotective properties, and free radical scavenger properties PMID 18788732
Biological activities of prostaglandin H1 analogs PMID 531224
SIB
Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium PMID 26045093
D
Design, Synthesis, and Biological Evaluation of Eukaryotic Initiation Factor 2B (eIF2B) Activators PMID 38426720
Design and synthesis of novel 1,2,3
Inhibition of the NLRP3 inflammasome by HSP90 inhibitors PMID 32954500
Mechanisms of tremor
Nicotinamide n
一切同源盒 3（ONECUT3）基因
Demethylzeylasteral protects against renal interstitial fibrosis by attenuating mitochondrial complex I
Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits PMID 19140153
Interplay between estrogen
Molecular Mechanisms of Cell Death in Leishmania donovani Induced by Selected Steroidal Alkaloids PMID 39604153
Reactive oxygen species contribute to lipopolysaccharide
A novel calcimimetic agent, evocalcet (MT
Phospho
The HSP90 inhibitor Onalespib exerts synergistic anti
Host engulfment pathway controls inflammation in inflammatory bowel disease PMID 32003126
HY
Highly selective SYK inhibitor, GSK143, abrogates survival signals in chronic lymphocytic leukaemia PMID 28770560
Mechanisms of protection against Clostridium difficile infection by the monoclonal antitoxin antibodies actoxumab and bezlotoxumab PMID 25486992
DMT
CCL21 expression pattern of human secondary lymphoid organ stroma is conserved in inflammatory lesions with lymphoid neogenesis PMID 17982129
pSTAT3 Y705 is a prognostic biomarker identified from time
COL1A1 expression induced by overexpression of both a 15‑amino acid peptide from the fibrinogen domain of tenascin‑X and integrin α11 in LX‑2 cells PMID 36069233
GPX4 Inhibition Contributes to NLRP3
Cyclin
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non
Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels PMID 18621927
2,7
LOC102143922
MCE
Timosaponin AIII Enhances Radiosensitivity in Breast Cancer through Induction of ROS
The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite PMID 17456192
Inhibition of voltage
MCE
Effect of regioisomers of hydroxystearic acids as peroxisomal proliferator
The renal membrane dipeptidase (dehydropeptidase I) inhibitor, cilastatin, inhibits the bacterial metallo
Born with Silurian global warming Defensive role of TRPV1 in caudal neurosecretory system (CNSS) in flounder PMID 40350111
Gab2 Rat Pre
Imidazo[4,5
Igsf11 Rat Pre
TUBB3 (βIII
Design, synthesis and biological evaluation of imidazopyridazine derivatives containing isoquinoline group as potent MNK1/2 inhibitors PMID 33971490
M2a macrophages regulate fibrosis and affect the outcome after stroke via PU.1/mTOR pathway in fibroblasts PMID 38184171
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets PMID 30451831
Ifnb1 Rat Pre
Discovery and characterization of novel ATP citrate lyase inhibitors from Acanthopanax senticosus (Rupr. & Maxim.) Harms PMID 38604261
Fondaparinux sodium a selective inhibitor of factor Xa PMID 11715834
DLRIE 199171
Ischemic Rescue Potential of Conditioned Medium Derived from Skeletal Muscle Cells
SYTL2 Human Pre
CDK2
Single BMSC
APPBP2 Human Pre
Lupane
Discovery of novel N
CRBN ligand
FGFR
The synthesis of 4
Tumor killing by a dietary curcumin mono
Schisandrin B exhibits anti
The BDNF val66met polymorphism affects activity
PrPC controls epithelial
Modulation of nongenomic activation of PI3K signalling by tetramerization of N
Evodiamine inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells via the SRC/ERBB2
Benzydamine N
Pirarubicin induces an autophagic cytoprotective response through suppression of the mammalian target of rapamycin signaling pathway in human bladder cancer cells PMID 25791481
The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano
Bioactive glycans in a microbiome
miR106a Promotes the Growth of Transplanted Breast Cancer and Decreases the Sensitivity of Transplanted Tumors to Cisplatin PMID 32021439
PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes PMID 18455211
Interleukin
Enterovirus 3A protein disrupts endoplasmic reticulum homeostasis through interaction with GBF1 PMID 38904364
[Glu27]
Matrine and Oxymatrine Evaluating the gene mutation potential using in silico tools and the bacterial reverse mutation assay (Ames test) PMID 37877816
Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2
Dual neutralisation of IL
Effect of Cannabidiolic Acid, N
MED1 Human Pre
Vidarabine a preliminary review of its pharmacological properties and therapeutic use PMID 6998693
Chemical Synthesis of a Locked Nucleic Acid
PHGDH Orchestrates Cell Cycle Progression to Drive Cardiomyocyte Proliferation and Myocardial Regeneration via TGF
EGIS
MEN1 silencing aggravates tumorigenic potential of AR
Identification of DOT1L inhibitors by structure
Pharmacokinetic and Pharmacodynamic integration of tilmicosin against Mycoplasma gallisepticum in the target infection site in chickens PMID 36246335
24R,25
Long non‑coding RNA DANCR promotes HMGA2‑mediated invasion in lung adenocarcinoma cells PMID 30535487
TRPA1 and TRPV1 contribute to iodine antiseptics
Impact of knockdown LincRNA
Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740 PMID 25063582
Dipeptidyl peptidase
Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5
Lysosomal P
Potent and selective chemical probe of hypoxic signalling downstream of HIF
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor PMID 2427071
Effects of HPV
AR
Actichinone, a new ursane triterpenoid from Actinidia chinensis roots, ameliorates NAFLD via the AMPK and NF
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp
TFRC 蛋白, Human (Biotinylated, HEK293, Fc
Potentiating dual
MCE
Attenuation of diabetic cardiomyopathy by relying on kirenol to suppress inflammation in a diabetic rat model PMID 31565849
Ubiquitin C
In vitro and clinical studies on the efficacy of α
Natural Product
CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia PMID 35253392
Mixture of clopidogrel bisulfate and magnesium oxide tablets reduces clopidogrel dose administered through a feeding tube PMID 33941283
Increased expression of Fas (CD95/APO
A Novel CMY Variant Confers Transferable High
Ginkgonitroside, a new nitrophenyl glycoside and bioactive compounds from Ginkgo biloba leaves controlling adipocyte and osteoblast differentiation PMID 34407463
Discovery of novel benzylidene
Impaired olfactory bulb neurogenesis mediated by Notch1 contributes to olfactory dysfunction in mice chronically exposed to methamphetamine PMID 39976779
Induction of apoptosis by pyrrolidinedithiocarbamate and N
Fragment
Inhibition of collagenase and metalloproteinases by aloins and aloe gel PMID 12479983
Chlamydia trachomatis upregulates lncRNA CYTOR to mediate autophagy through miR
Differential effects of fatty acyl coenzyme A derivatives on citrate synthase and glutamate dehydrogenase PMID 8122033
Vaxfectin enhances the humoral immune response to plasmid DNA
MCE
CC Chemokines in a Tumor A Review of Pro
Ptges3
Chronic (1
An Interleukin
Antineoplastic agents. 578. Synthesis of stilstatins 1 and 2 and their water
Comparative biological activities of the four synthetic (5,6)
The discovery of SB
Inhibition of transcellular tumor cell migration and metastasis by novel carba
Florfenicol induced renal inflammatory response and apoptosis via cell adhesion molecules signaling pathway PMID 36152436
Neuronal NLRP1 inflammasome activation of Caspase
Unveiling the Role of Sik1 in Osteoblast Differentiation Implications for Osteoarthritis PMID 39169784
First Selective 12
IL
Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect PMID 20410884
Structural role of K224 in taniborbactam inhibition of NDM
HA1/Hemagglutinin 蛋白, H3N2 (ABX10525, HEK293, His)
Identification of potential therapeutic targets in prostate cancer through a cross
Full
Radotinib dihydrochloride 926037
Design, synthesis and biological evaluation of substituted pyrrolo[2,3
Beneficial effects of brown fat activation on top of PCSK9 inhibition with alirocumab on dyslipidemia and atherosclerosis development in APOE*3
Morin, a matrix metalloproteinase 9 inhibitor, attenuates endothelial
Destruction of self
Enhancement of bile resistance in Lactobacillus plantarum strains by soy lecithin PMID 25800811
Alirocumab First Global Approval PMID 26370210
Discovery of AB801, a Potent and Selective Inhibitor of AXL Receptor Tyrosine Kinase for Use in Cancer Therapy PMID 40407274
Low sperm quality and increased testicular caspases in chronic stress mice induced by dexamethasone PMID 40465972
The Mechanism and Diagnostic Value of the LINC01220/hsa
In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP
Antidepressant
Discovery of selective hexapeptide agonists to human neuromedin U receptors types 1 and 2 PMID 24999562
Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo PMID 34446736
One new pregnane glycoside from the seeds of cultivated Brucea javanica PMID 21910051
Recent advances in the design and discovery of synthetic tyrosinase inhibitors PMID 34365131
3
Al adjuvants can be tracked in viable cells by lumogallion staining PMID 25896212
m
Cytotoxic activity of Shp2 inhibitor fumosorinone in human cancer cells PMID 29928374
Integrated genomics point to immune vulnerabilities in pleural mesothelioma PMID 34580349
基质金属肽酶 9（Mmp9）基因
Voriconazole the newest triazole antifungal agent PMID 16278744
S
Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis PMID 25738750
Discovery and optimization of piperidyl
ASK1
Effects of IDO1 and TDO2 inhibition on cognitive deficits and anxiety following LPS
Taraxasterol protects against acetaminophen
The novel phosphodiesterase 10A inhibitor THPP
A peptidomimetic modulator of the CaV2.2 N
Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim
Discovery of conformationally constrained c
Lamiridosins, hepatitis C virus entry inhibitors from Lamium album PMID 19904996
SKI Human Pre
YAP1 is a key regulator of EWS FLI1
TDN345 134069
硫酸乙酰肝素
Rubimetide, humanin, and MMK1 exert anxiolytic
Bioactivity
β
Synthesis and Pharmacological Evaluation of Noscapine
GIT ArfGAP 2（GIT2）基因
IL
Florfenicol inhibits allergic airway inflammation in mice by p38 MAPK
Small
MELK as a Mediator of Stemness and Metastasis in Aggressive Subtypes of Breast Cancer PMID 40076867
Treatment with 7% and 10% CO2 enhanced expression of IL
Structure and chromosomal localization of the human PD
Curcumin/pEGCG
Botulinum toxin type A inhibits M1 macrophage polarization by deactivation of JAK2/STAT1 and IκB/NFκB pathway and contributes to scar alleviation in aseptic skin wound healing PMID 38518603
Design, synthesis, SAR discussion, in vitro and in vivo evaluation of novel selective EGFR modulator to inhibit L858R/T790M double mutants PMID 28426996
RGFP966 is protective against lipopolysaccharide
Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus PMID 12585686
A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats PMID 14750027
CD200R1 蛋白, Human (Biotinylated, HEK293, Fc
Editorial Advances in molecular and pharmacological mechanisms of novel targeted therapies for melanoma PMID 38638856
DYRK1A reinforces epithelial
BMP2 induces osteogenic differentiation through ACKR3 in mesenchymal stem cells PMID 37141639
Factor Xa and thrombin induce endothelial progenitor cell activation. The effect of direct oral anticoagulants PMID 32762584
Massive cell vacuolization induced by organic amines such as procainamide PMID 15007104
6,6'
MG132
Discovery of XRF
Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long
A novel di
PTPRN Human Pre
Long
Expression Pattern of Individual IFNA Subtypes in Chronic HIV Infection PMID 29252127
Discovery and radiosensitization research of ursolic acid derivatives as SENP1 inhibitors PMID 34688014
CXCL13 activation of c
Preclinical efficacy of CBR
Directly acting antivirals against hepatitis C virus PMID 21652618
Benzyl
Beta A4 amyloid protein and its precursor in Alzheimer's disease PMID 1297146
Auriculasin enhances ROS generation to regulate colorectal cancer cell apoptosis, ferroptosis, oxeiptosis, invasion and colony formation PMID 34872005
Harmine exerts anxiolytic effects by regulating neuroinflammation and neuronal plasticity in the basolateral amygdala PMID 37150016
Bisindolylmaleimide I hydrochloride 176504
PRKRA Human Pre
Celecoxib and sulindac sulfide elicit anticancer effects on PIK3CA
KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus PMID 39702240
Folic acid administration produces an antidepressant
SLC30A2 蛋白, Human (sf9, His, MBP, FLAG)
Protein arginine methyltransferase 5 mediates THP
Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage PMID 35287697
Caspase
The recent progress of peptide regulators for the Wnt/β
Inhibition of histamine receptor 3 alleviates sevoflurane
Real
Effects of metal ions on caspase
Targeting Triple
Anticonvulsant actions of LY 367385 ((+)
The role of vitamin K and its antagonist in the process of ferroptosis
Modular Peptide Probe for Pre/Intra/Postoperative Therapeutic to Reduce Recurrence in Ovarian Cancer PMID 33174739
Acylated apelin
What makes an allergen? PMID 25989479
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma PMID 22197931
Metabolic reprogramming nanomedicine potentiates colon cancer sonodynamic immunotherapy by inhibiting the CD39/CD73/ADO pathway PMID 40487643
Prim
AZD
CCL2 a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir PMID 36073812
H
Ivabradine possesses anticonvulsant and neuroprotective action in mice PMID 30551511
Hydroxyamidine inhibitors of indoleamine
RABEP1 Human Pre
DNMT1/DNMT3a
Antisense oligonucleotide targeting nicotinamide N
LIB
PPARα is one of the key targets for dendrobine to improve hepatic steatosis in NAFLD PMID 38171466
Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery PMID 25756299
SIDT1
Thrombomodulin 蛋白, Human (HEK293, His, solution)
Synthesis and antitumor activity of novel silibinin and 2,3
CD33 抗体 (YA4715)（CD33 Antibody (YA4715)）
In vitro and in vivo antibacterial activities of AT
Anti
Orai2 deficiency attenutates experimental colitis by facilitating the colonization of Akkermansia muciniphila PMID 36070824
Preclinical evaluation of docusate as protective agent from herpes simplex viruses PMID 11530185
CL
Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM
S
Discovery, Multiparametric Optimization, and Solid
HSP70 is a chaperone for IL
Saikosaponin D isolated from Bupleurum falcatum inhibits selectin
Allolithocholic acid 2276
H
Selective regulation of RANKL/RANK/OPG pathway by heparan sulfate through the binding with estrogen receptor β in MC3T3
Synthesis and Evaluation of [18F]AlF
Discovery and preclinical development of AR453588 as an anti
Swertiamarin, a natural steroid, prevent bone erosion by modulating RANKL/RANK/OPG signaling PMID 29078090
LSKL peptide alleviates subarachnoid fibrosis and hydrocephalus by inhibiting TSP1
Dual Farnesyl and Geranylgeranyl Transferase Inhibitor Thwarts Mutant KRAS
The selective sphingosine 1
Partitioning of cancer therapeutics in nuclear condensates PMID 32554597
Lipid Composition Alters Ferroptosis Sensitivity PMID 40911781
PCSK9 inhibition with alirocumab reduces lipoprotein(a) levels in nonhuman primates by lowering apolipoprotein(a) production rate PMID 29724769
Hepatitis C virus diversity and treatment outcomes in Benin a prospective cohort study PMID 38889738
Novel triphenylphosphonium amphiphilic conjugates of glycerolipid type synthesis, cytotoxic and antibacterial activity, and targeted cancer cell delivery PMID 36970146
Dmbt1 Mouse Pre
Dual function of peroxiredoxin I in lipopolysaccharide
同源框 B7（HOXB7）基因
Vasorin
IL
Defining a TFAP2C
The hepatoprotective effect and chemical constituents of total iridoids and xanthones extracted from Swertia mussotii Franch PMID 24746481
Lrrk1 Rat Pre
In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor PMID 36448795
Farnesoid X receptor is inhibited after ileum transposition in diabetic rats its hypoglycemic effect PMID 37082732
Binding of a highly potent protease
Identification of Crucial Residues in α
Matrine suppresses lung cancer metastasis via targeting M2
Fmoc
Targeting Heat Shock Protein 70 to Ameliorate c
PLAGL1 抗体 (YA4575)（PLAGL1 Antibody (YA4575)）
Ruscogenin suppressed the hepatocellular carcinoma metastasis via PI3K/Akt/mTOR signaling pathway PMID 29477471
The winding road of the uvaretin class of natural products from total synthesis to bioactive agent discovery PMID 31673309
Synthesis and biological evaluation of novel, peripherally selective chromanyl imidazolethione
DL
Promethazine protection in carbon tetrachloride liver injury. An electron microscopic study PMID 5782435
The discovery of histone demethylases PMID 24003214
Phospho
High
Structural dependence of antidiabetic effect of steviol glycosides and their metabolites on streptozotocin
Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses PMID 24218580
MELK is a novel therapeutic target in high
Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors PMID 34800887
Structure
(R)
Identification of endocannabinoid system
Hepcidin 抗体 (YA6601)（Hepcidin Antibody (YA6601)）
Synthesis and structure
A Randomized, Placebo
Efficacy of Onalespib, a Long
Discovery of an Orally Bioavailable and Central Nervous System (CNS) Penetrant mGlu7 Negative Allosteric Modulator (NAM) in Vivo Tool Compound N
Development of Tailless Homologue Receptor (TLX) Agonist Chemical Tools PMID 39236094
The effects of clavulanic acid and amoxicillin on cue
2
YB1 regulates miR
Regulation of circadian behaviour and metabolism by synthetic REV
The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)
JMV 2959 hydrochloride 2448414
lncRNA CASC19 Contributes to Radioresistance of Nasopharyngeal Carcinoma by Promoting Autophagy via AMPK
Isoquercitrin mitigates intestinal ischemia
Norfluoxetine
The acetaminophen metabolite N
MCE
Treatment of Bleomycin
Pxn
Identification of a novel small molecule HIF
Synthesis and biological evaluation of novel biaryl type α
ROS enhances the cytotoxicity of cisplatin by inducing apoptosis and autophagy in tongue squamous cell carcinoma cells PMID 32097729
Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators PMID 29966094
Choleretic activity of phloracetophenone in rats structure
POM
Preparation and characterization of photosensitive methacrylate
2,3
Semisynthesis, cytotoxicity, antimalarial evaluation and structure
EG35
Antimicrobial agent
Opposing responses of the rat pulmonary artery and vein to phenylephrine and other agents in vitro PMID 34090386
S
[1,1' 3',1'' 4'',1'''
Synthesis and antiproliferative activity of conformationally restricted 1,2,3
Structural Insights on Hyp
Flurbiprofen axetil attenuates cerebral ischemia/reperfusion injury by reducing inflammation in a rat model of transient global cerebral ischemia/reperfusion PMID 29540536
Ube2z Rat Pre
PPACK TFA 157379
CDK7 is a component of the integrated stress response regulating SNAT2 (SLC38A2)/System A adaptation in response to cellular amino acid deprivation PMID 30857869
Prediction of the mechanisms of action of Zhibai Dihaung Granule in cisplatin
The Antidepressant Mirtazapine Inhibits Hepatic Innate Immune Networks to Attenuate Immune
Lactate promotes metastasis of normoxic colorectal cancer stem cells through PGC
Nifurpipone
Next
5
UNC6852 2688842
Pharmacologic inhibition of the Menin
蛋白质二硫键异构酶家族 A 成员 3（PDIA3）基因
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