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生物活性分子最近更新
In Silico Identification of Novel and Potent Inhibitors Against Mutant BRAF (V600E), MD Simulations, Free Energy Calculations, and Experimental Determination of Binding Affinity PMID 40524540
MiR
Discovery of the first chemical tools to regulate MKK3
Polydatin Improves Sepsis
Oroxyloside inhibits angiogenesis through suppressing internalization of VEGFR2/Flk
Ti
Fructose 1,6
Gastrodin promotes CNS myelinogenesis and alleviates demyelinating injury by activating the PI3K/AKT/mTOR signaling PMID 40011630
The peptidomimetic CXCR4 antagonist TC14012 recruits beta
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c
Anti
Rhealba® oat plantlet extract evidence of protein
Chemokine CXCL13 facilitates anti
OTUB2 抗体 (YA4421)（OTUB2 Antibody (YA4421)）
4
Evaluation of SSR161421, a novel orally active adenosine A3 receptor antagonist on pharmacology models PMID 23219796
Bioactive Phenanthrene and Bibenzyl Derivatives from the Stems of Dendrobium nobile PMID 27310249
Molecular determinants of angiotensin II type 1 receptor functional selectivity PMID 18848837
A Jagged 1
Swertiamarin attenuates inflammation mediators via modulating NF
Tiotropium bromide for chronic obstructive pulmonary disease PMID 20477315
Further studies on the potent positive chronotropic effect of (15S)
Dynein
Qianyang Yuyin granules alleviate hypertension
Rescuing fertility Itaconic acid prevents ovarian damage through NRF2
Evodiamine inhibits malignant progression of ovarian cancer cells by regulating lncRNA
Oroxyloside ameliorates acetaminophen
Inhibition of super enhancer downregulates the expression of KLF5 in basal
Targeting the isoprenoid pathway in choleste biosynthesis An approach to identify isoprenoid biosynthesis inhibitors PMID 39945543
CD5 蛋白, Human (214a.a, HEK293, Fc)
IL
Inhibition of formyl peptide
Tankyrase activity is essential for asymmetric division and chromosome segregation in oocyte meiosis PMID 40633837
Mouse gamete interactions during fertilization in vitro. Chlortetracycline as a fluorescent probe for the mouse sperm acrosome reaction PMID 574869
Matrix 蛋白 1/M1 蛋白, H7N9 (EPI439506, His)
Marine natural products as novel antioxidant prototypes PMID 12762791
Heme in pathophysiology a matter of scavenging, metabolism and trafficking across cell membranes PMID 24782769
Atrial natriuretic factor receptors in cultured renomedullary interstitial cells PMID 2159215
Activated PPARβ/δ Protects Pancreatic β Cells in Type 2 Diabetic Goto
MCE
W
Synthesis and in vitro antifolate activity of rotationally restricted aminopterin and methotrexate analogues PMID 15615544
Antibiotic drug levofloxacin inhibits proliferation and induces apoptosis of lung cancer cells through inducing mitochondrial dysfunction and oxidative damage PMID 27780143
BAY
High concentrations of pyridoxal stimulate the expression of IGFBP1 in HepG2 cells through upregulation of the ERK/c‑Jun pathway PMID 23942851
High
GM
Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors PMID 28816449
CDK7 inhibition by THZ1 suppresses cancer stemness in both chemonaïve and chemoresistant urothelial carcinoma via the hedgehog signaling pathway PMID 33741425
Identification of a small molecule inhibitor of 3
卡尔迪斯蒙 1（CALD1）基因
Overexpression of PPT2 Represses the Clear Cell Renal Cell Carcinoma Progression by Reducing Epithelial
Renoprotective effects of novel interleukin
Effects of formamide on neuroepithelial cells and on interkinetic nuclear migration in the chick embryo PMID 1270979
Panduratin A, an activator of PPAR
RANK ligand and osteoprotegerin paracrine regulators of bone metabolism and vascular function PMID 11950689
Hepatocyte Thorns, A Novel Drug
Prodigiosin inhibits Wnt/β
OTUB2 Human Pre
PSN 375963 hydrochloride
Cardiotoxic Antiemetics Metoclopramide and Domperidone Block Cardiac Voltage
The effect of neonicotinoid insecticide thiacloprid on the structure and stability of DNA PMID 32118477
Sodium butyrate alleviates cholesterol gallstones by regulating bile acid metabolism PMID 34273384
A PHGDH inhibitor reveals coordination of serine synthesis and one
P21
RB
Acute Plasmodium Infection Promotes Interferon
IRF9 Human Pre
New Preclinical Development of a c
Metabotropic glutamate receptor 5 negative allosteric modulators as novel tools for in vivo investigation PMID 22924094
Ursodeoxycholic acid protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis in MPTP/MPP+
The Crystal Structure of Acanthamoeba Polyphaga Mimivirus R655 and Its Potential Glycosaminoglycan Glycosyltransferase Activity PMID 40545624
Hinnuliquinone, a C2
Coronavirus S protein alters dsRNA accumulation and stress granule formation through regulation of ADAR1
mmu
A New Use for an Old Drug Carmofur Attenuates Lipopolysaccharide (LPS)
Analgesic and convulsant effects of guanidinoethylmercaptosuccinic acid (GEMSA)
Targeted inhibition of telomerase activity combined with chemotherapy demonstrates synergy in eliminating ovarian cancer spheroid
A non
Pasireotide (SOM230) development, mechanism of action and potential applications PMID 17977644
On Monolayer Formation of Pyrenebutyric Acid on Graphene PMID 28350965
Evodiamine Boosts AR Expression to Trigger Senescence and Halt Proliferation in OSCC Cells PMID 40729027
Marsdenia tenacissima extract accelerates ferroptosis of osteosarcoma cells by upregulating HO
Gum arabic reduces inflammation, oxidative, and nitrosative stress in the gastrointestinal tract of mice with chronic kidney disease PMID 32157347
Gallic acid improves glucose tolerance and triglyceride concentration in diet
Acrolein scavengers and detoxification From high
Neamine induces neuroprotection after acute ischemic stroke in type one diabetic rats PMID 24211797
Ofloxacin, a bactericidal antibacterial PMID 1646700
The role of β2
Evaluation of the safety of long
Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2 PMID 25626146
Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti
Discovery of Novel Potent and Selective Agonists at the Melanocortin
Development of 2
GSK 690 2101305
Discovery of Quinoline Analogues as Potent Antivirals against Enterovirus D68 (EV
Induction of cellular differentiation by retinoic acid in vitro PMID 10592391
Photoimmunotherapy of hepatocellular carcinoma
Tannic acid as a biphasic modulator of tau protein liquid
Efficacy and Mechanism of Action of Marine Alkaloid 3,10
Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl
An example of molecular co
Gegen Qinlian Decoction Ameliorates Hepatic Insulin Resistance by Silent Information Regulator1 (SIRT1)
PRL3
The effect of treatment with a new antidepressant, INN 00835, on platelet serotonin uptake in depressed patients PMID 10628893
Synthesis and anti
CD39+ Fibroblasts Enhance Myofibroblast Activation by Promoting IL
Modulation of pharmacokinetics of theophylline by antofloxacin, a novel 8
Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF
Systemic administration of the di
HNHA 926908
Structure
7568
[Effects of 9,10
Human mesenchymal stromal/stem cells acquire immunostimulatory capacity upon cross
Adolescent social isolation decreases colonic goblet cells and impairs spatial cognition through the reduction of cystine PMID 39613916
Ceftriaxone Protects Astrocytes from MPP(+) via Suppression of NF
Gpi1
The long
Epithelial sodium channel inhibition in cardiovascular disease. A potential role for amiloride PMID 17198922
Design, synthesis and antitumor evaluation of novel celastrol derivatives PMID 31051401
New pyrazolopyrimidine derivatives with anticancer activity Design, synthesis, PIM
Ras signaling and RREB1 are required for the dissociation of medial edge epithelial cells in murine palatogenesis PMID 34897389
Agonist or antagonist what is preferable for in vitro fertilization? PMID 22394299
CI
Myosin light chain kinase
Rapid production method with increased yield of high
Mechanosensitive cation currents through TRPC6 and Piezo1 channels in human pulmonary arterial endothelial cells PMID 35968892
(
Curcumol attenuates epithelial
Metabolic disturbances identified in plasma are associated with outcomes in patients with heart failure diagnostic and prognostic value of metabolomics PMID 25881932
Identification of LY2510924, a novel cyclic peptide CXCR4 antagonist that exhibits antitumor activities in solid tumor and breast cancer metastatic models PMID 25504752
Lemuteporfin (QLT
CS92
Thapsigargicin 67526
Moxisylyte a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in impotence PMID 9711459
MCE
MCE
The tyrosine phosphatase SHP2 promotes proliferation and oxaliplatin resistance of colon cancer cells through AKT and ERK PMID 34052504
Hirsutane sesquiterpenes from the fungus Lentinus connatus BCC 8996 PMID 16309322
S
Selective hexapeptide agonists and antagonists for human complement C3a receptor PMID 20527893
Danirixin 954126
CCR7 and CD48 as Predicted Targets in Acute Rejection Related to M1 Macrophage after Pediatric Kidney Transplantation PMID 38957433
9
Structure
Cetuximab sarotalocan 2166339
Levocabastine hydrochloride 79547
The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation PMID 29930278
hsa
2
COX
Angelicin regulates LPS
Synthesis and biological properties of benzothiazole, benzoxazole, and chromen
Bisoxatin 17692
Glycohyodeoxycholic acid 13042
Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1
MsDUF3700 overexpression enhances aluminum tolerance in alfalfa shoots PMID 39630276
trans
Lindera cyclopentenedione intermediates from the roots of Lindera aggregata PMID 35542074
ALKBH5
COG1410 878009
5
Paeoniflorin alleviated experimental Sjögren's syndrome by inhibiting NLRP3 inflammasome activation of submandibular gland cells via activating Nrf2/HO
Fast Green FCF Attenuates Lipopolysaccharide
Sesame oil protects against lead
Identification and structure
Etiroxate 17365
Prochloraz 67747
Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats PMID 23123262
3’
Selective, reversible inhibitors of the AAA ATPase p97 PMID 23658965
VCAM
The metabolites of a mangrove endophytic fungus, Penicillium thomi PMID 17454313
Slc39a6
hsa
Residue dynamics and bio
Aclidinium 727649
Hematoporphyrin derivative
In vitro facilitating role of polygonatum sibiricum polysaccharide in osteogenic differentiation of bone marrow mesenchymal stem cells from patients with multiple myeloma PMID 33891231
Pyrido[2,3
Influenza A virus proteins PB1 and NS1 are subject to functionally important phosphorylation by protein kinase C PMID 19264651
SHC2 Human Pre
Development of specific Rho
Selenocystamine dihydrochloride
核糖体 BRX1 的生物发生（BRIX1）基因
Effect of fenofibrate and LF 2151 on hepatic peroxisomes in hamsters PMID 6508822
JNK3
Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR
Two new secondary metabolites isolated from Avena sativa L. (Oat) seedlings and their effects on osteoblast differentiation PMID 32527550
Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase Structure
HY
Preventive actions of a synthetic antioxidant in a novel animal model of AIDS dementia PMID 9622673
Calcium 2
Total synthesis of (
PtdIns
Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor
Inhibition of Aryl Hydrocarbon Receptor Attenuates Hyperglycemia
CSL360
A Membrane
Tetraglycine 637
Actithiazic acid
4
Anti
Protamine
Structure of the superantigen staphylococcal enterotoxin B in complex with TCR and peptide
MCE
Piperoxan 59
IL
溶质载体家族 6 成员 16（SLC6A16）基因
NRF2/ARE mediated antioxidant response to glaucoma role of glia and retinal ganglion cells PMID 37875948
Studies on the constituents of asclepiadaceae plants. LVIII. The structures of five glycosides, cynatratoside
Putting the brakes on phagocytosis don't
Assessment of Activity and Resistance Mechanisms to Cefepime in Combination with the Novel β
TRIM19 enhances the chemosensitivity of endometrial cancer by regulating the TBX2/NRF2 axis PMID 40465083
Suppression of isoprenylcysteine carboxylmethyltransferase compromises DNA damage repair PMID 34610973
Protocol for whole
Phosphatidylinositol bis
Met343Val mutation disrupts the shuttling of Trp380 leading to a low
Synthesis, molecular modeling and antiviral activity of novel 5
Regiospecific Introduction of Halogens on the 2
5
Efdelikofusp alfa 2922216
Pseudorabies virus infection inhibits stress granules formation via dephosphorylating eIF2α PMID 32768230
Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy PMID 12738711
Pharmacologic effects of A
High frequency of T cells specific for cryptic epitopes in melanoma patients PMID 24073381
ER
rel
Cdcp1
A new potent and selective non
TG (18 1_20 2_20 4)
ProTides of BVdU as potential anticancer agents upon efficient intracellular delivery of their activated metabolites PMID 27818111
Targeting Cancer Metabolism to Improve Outcomes with Immune Checkpoint Inhibitors PMID 37214204
Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis PMID 38979280
Tyrosine kinase inhibitors. 11. Soluble analogues of pyrrolo
Discovery of inhibitors that elucidate the role of UCH
Gut microbial dysbiosis exacerbates long
Inhibition of cholesterol biosynthesis impairs insulin secretion and voltage
Adenosine metabolic clearance maintains liver homeostasis by licensing arginine methylation of RIPK1 PMID 41081715
The GAS6
Developing new chemical tools for DNA methyltransferase 1 (DNMT 1) a small
Interaction of Ectodomain of Respiratory Syncytial Virus G Protein with TLR2/ TLR6 Heterodimer An In vitro and In silico Approach to Decipher the Role of RSV G Protein in Pro
AUF1
Dapivirine hydrochloride 244768
Targeted Dual
Platelet aggregation
The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine
Single
CBZ
Osteopontin promotes hepatocellular carcinoma progression through inducing JAK2/STAT3/NOX1
Idarubicin 58957
The human CXC chemokine granulocyte chemotactic protein 2 (GCP
Guselkumab 1350289
Tumor Targeting with Methotrexate
Blockade of myeloid
Modulating Effects of Spirulina platensis against Tilmicosin
Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants PMID 38740822
Terpenoids from Euphorbia pedroi as Multidrug
Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor PMID 25490451
4,4',4'',4'''
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC PMID 37490552
Stub1 Mouse Pre
Ligand
Cathepsin L
Aromatase inhibitors synthesis, biological activity, and binding mode of azole
Utilization of cyanopyridine in design and synthesis of first
SAR Studies of Exosite
Mitochondrial separation protein inhibitor inhibits cell apoptosis in rat lungs during intermittent hypoxia PMID 30867720
Regulation of Chlamydomonas flagella and ependymal cell motile cilia by ceramide
Cadherin
Ziconotide a review of its pharmacology and use in the treatment of pain PMID 19300539
Novel pharmacology asimadoline, a kappa
Obesity Promotes Tumor Immune Evasion in Ovarian Cancer Through Increased Production of Myeloid
Phenylamino
Co
Generation of human induced pluripotent stem cell
5′
LHX1 Human Pre
Portable Near
Iodide Improves Outcome After Acute Myocardial Infarction in Rats and Pigs PMID 30063489
Surficial nano
Dysfunction in atox
Pyridazine as a privileged structure An updated review on anticancer activity of pyridazine containing bioactive molecules PMID 33129590
Discovery and In Vivo Exploration of 1,3,4
MCE
4
Fem1b Mouse Pre
Hypoxia improves self
Identification of a novel, small molecule inhibitor of KCNQ2 channels PMID 23658963
Synthesis and antiplasmodial activity of aminoalkylamino
Perfluorooctane sulfonate causes pyroptosis and lipid metabolism disorders through ROS
In vitro effects of three equimolar concentrations of methylprednisolone acetate, triamcinolone acetonide, and isoflupredone acetate on equine articular tissue cocultures in an inflammatory environment PMID 30153056
Injectable hydrogel regulates immune infiltration through physical and chemical synergy in the treatment of steroid
Engineered endoplasmic reticulum
Dipsacus saponin XII 149558
Exosomal microRNA
Dual
Targeted xCT
Z
Ginsenoside Rk1 Ameliorates ER Stress
Double vulnerability of active
Discovery of a potent dual ALK and EGFR T790M inhibitor PMID 28528303
Regulation of astrocyte proliferation by FGF
DNMT1 expression partially dictates 5
Integrated spatial multi
A microbial amino
GAS6 attenuates sepsis
Biological effects of gum arabic a review of some recent research PMID 18672018
Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides PMID 35788180
DDR1/2 enhance KIT activation and imatinib resistance of primary and secondary KIT mutants in gastrointestinal stromal tumors PMID 37737519
Effects of sarcosine and N, N
Interleukin 13 is a B cell stimulating factor PMID 7903680
6
Intraperitoneally Delivered Mesenchymal Stem Cells Alleviate Experimental Colitis Through THBS1
Exposure to escalating olaparib does not induce acquired resistance to PARPi and to other chemotherapeutic compounds in ovarian cancer cell lines PMID 35642662
Kinetics of macrolide action the josamycin and erythromycin cases PMID 15385552
Indeno[1,2,3
THBS2
Oroxyloside inhibits liver fibrosis and hepatocarcinogenesis dependent on hepatocyte
Dual targeting of EGFR and ERBB2 pathways produces a synergistic effect on cancer cell proliferation and migration in vitro PMID 27229930
RO 16
GFRA3/GDNFR
Ferolin 39380
Molecular design, synthesis, and structure
Angiotensin II protects primary rat hepatocytes against bile salt
TFF3 蛋白, Mouse (HEK293, His)
Calibrated ribosome profiling assesses the dynamics of ribosomal flux on transcripts PMID 39187487
Mbd1
Epigenetic modulation of glycoprotein VI gene expression by DNA methylation PMID 31783053
GDF
I(f) channel inhibitor ivabradine lowers heart rate in mice with enhanced sympathoadrenergic activities PMID 15066901
TACR1 Human Pre
Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Stephania erecta PMID 8450319
MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation PMID 30928206
Hippocampal Oligodendrocytes Regulate Mossy Fiber Development Involved in Epileptic Responses PMID 40673958
Discovery of novel quaternary ammonium derivatives of (3R)
Dendrobine Inhibits γ
Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry PMID 32899354
Metabolic activation of tachysterol3 to biologically active hydroxyderivatives that act on VDR, AhR, LXRs, and PPARγ receptors PMID 35838947
Cysteine Cathepsins Inhibition Affects Their Expression and Human Renal Cancer Cell Phenotype PMID 32455715
Convergent alteration of the mesenchymal stem cell heterogeneity in adipose tissue during aging PMID 37498236
Design of thiazole orange oligonucleotide probes for detection of DNA and RNA by fluorescence and duplex melting PMID 31157811
SIRP alpha V8/CD172a 蛋白, Human (AAH38510, HEK293, His)
Comparison of human cytochrome P450 inhibition by the thienopyridines prasugrel, clopidogrel, and ticlopidine PMID 19122335
Trisomy 21
Psammaplin A, a marine natural product, inhibits aminopeptidase N and suppresses angiogenesis in vitro PMID 14732224
Effect of 4
ZAP70 抗体 (YA5523)（ZAP70 Antibody (YA5523)）
An improved method for beta
Viable mutations of mouse midnolin suppress B cell malignancies PMID 38625151
MEPE/OF45 蛋白, Mouse (HEK293, His)
The Nurr1 Activator 1,1
Ethacrynic acid decreases expression of proinflammatory intestinal wall cytokines and ameliorates gastrointestinal stasis in murine postoperative ileus PMID 30365818
Melatonin alleviates cholestatic liver injury through modulating gut microbiota and activating the NRF2/HO
GFRA1
Characterization of SPP inhibitors suppressing propagation of HCV and protozoa PMID 29187532
β
Pharmacological Targeting of DHHC9
Biological characterization of ARRY
ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7 in vitro and in vivo characterization PMID 23257312
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF
Pharmacology of AM211, a potent and selective prostaglandin D2 receptor type 2 antagonist that is active in animal models of allergic inflammation PMID 21487069
ACLY inhibition promotes tumour immunity and suppresses liver cancer PMID 40739358
Acute hepatitis associated with alosetron (Lotronex) PMID 16000936
Oleanolic acid modulates the immune
Non
Effect of anticoagulants on fibrin clot structure A comparison between vitamin K antagonists and factor Xa inhibitors PMID 33313466
Prevotella Induces the Production of Th17 Cells in the Colon of Mice PMID 33204736
AT
Anti
Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor PMID 25864624
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase
Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme PMID 21764822
OTUB2 抗体 (YA4421)(PBS only)（OTUB2 Antibody (YA4421)(PBS only)）
Gnai3
Structure
Efficient biocatalytic production of D
Steady
AMPA receptor inhibition alleviates inflammatory response and myocardial apoptosis after myocardial infarction by inhibiting TLR4/NF
RNA Polymerases I/II/III Subunit ABC1 抗体 (YA1684)（RNA Polymerases I/II/III Subunit ABC1 Antibody (YA1684)）
Isolation and characterization of new p
2,5
Dysregulated GLUT1 results in the pathogenesis of preeclampsia by impairing the function of trophoblast cells PMID 39390043
Oxidative stress induced pyroptosis leads to osteogenic dysfunction of MG63 cells PMID 32356234
Sult1b1 Rat Pre
Investigating the potential mechanism and therapeutic effects of SLXG for cholesterol gallstone treatment PMID 39059092
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice PMID 38375215
Fumosorinone, a novel PTP1B inhibitor, activates insulin signaling in insulin
Membrane composition
Comparative in vitro activity of sitafloxacin against bacteria isolated from Thai patients with urinary tract infections and lower respiratory tract infections PMID 22574524
Copper peroxide/manganese dioxide nanoparticles crosslinked hyaluronan hydrogel for enhanced chemodynamic/photodynamic/photothermal therapy in breast cancer PMID 41037888
Mature osteoclast
PARP inhibition enhances tumor cell
The pyruvate
Cytoprotective constituent of Hoveniae Lignum on both Hep G2 cells and rat primary hepatocytes PMID 17679542
HWGMWSY 348082
Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti
Small
Histone Methyltransferases as Therapeutic Targets for Kidney Diseases PMID 31866860
Cwc15 Mouse Pre
TOX Human Pre
New flurbiprofen derivatives synthesis, membrane affinity and evaluation of in vitro effect on β
Impairment of gastric accommodation induced by water
The effect of newer serotonin
Antioxidants, oxidative stress, and degenerative neurological disorders PMID 10601882
In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity PMID 36559057
Central human cocaine
SHR5133 2270943
1
Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase PMID 24520856
MCE
Daclizumab 152923
Reprint of Detection and Impact of Hypoxic Regions in Multicellular Tumor Spheroid Cultures formed by Head and Neck Squamous Cell Carcinoma Cells Lines PMID 38101574
Nanoparticulate MgH2 ameliorates anxiety/depression
Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators PMID 20079636
Targeting the mitogen
Myeloid Differentiation Primary Response Protein 88 (MyD88) The Central Hub of TLR/IL
Calpinactam, a new anti
6,6'
Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5 PMID 29490668
GKL003
Chronic di(2
Toltrazuril sulfoxide 69004
Arnocoumarin 11037
MCE
Epitope mapping by a Wnt
Azido
Amylmetacresol/2,4
Amphiepicoccins A
CRBN ligand
3
Expression and prognostic analyses of the insulin
Glycyrrhizin improves the pathogenesis of psoriasis partially through IL
GCN5/KAT2A contributes to axon growth and neurogenesis PMID 35716963
Anticancer activity of 8
[Arg(14),Lys(15)]nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor in vitro and in vivo studies PMID 11752097
MiR
BHQ
Identification, synthesis, and pharmacological evaluation of tetrahydroindazole based ligands as novel antituberculosis agents PMID 20000470
TAK1
(S,R,S)
PVRIG 蛋白, Cynomolgus (HEK293, Fc)
Anti
CRBN ligand
Filricianine sodium 2140857
(S)
Preventing murine transfusion
Expansion and Precise CRISPR
AP3S2 Human Pre
A17 peptide 1140483
KDELR2 promotes bone marrow mesenchymal stem cell osteogenic differentiation via GSK3β/β
SR
IL
1
Oligosaccharyltransferase inhibition induces senescence in RTK
SMAD3 and p300 complex scaffolding by long non
Vaxfectin a versatile adjuvant for plasmid DNA
TRIM3 suppressed the tumorigenicity of melanoma cells by ubiquitinating YAP1 PMID 40715334
Pharmacological TLR4 Antagonism Using Topical Resatorvid Blocks Solar UV
Mechanism of porcine pancreatic alpha
Proquinazid (丙氧喹啉)
GPR39 promotes cardiac hypertrophy by regulating the AMPK
Succinylacetone, a potent inhibitor of heme biosynthesis effect on cell growth, heme content and delta
1
8
Update on roflumilast, a phosphodiesterase 4 inhibitor for the treatment of chronic obstructive pulmonary disease PMID 21232047
Drug synergism of antihypertensive action in combination of telmisartan with lercanidipine in spontaneous hypertensive rats PMID 20945140
Potent inhibitory activity of HSR
PEG
Cdcp1 Mouse Pre
Inhibition of SARS
HMGCL activates autophagy in osteosarcoma through β
(Rac)
Targeting dihydroorotate dehydrogenase (DHODH) for host
Ned 19 874374
Cardiac endothelial cell
ADRA1A Human Pre
L
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF
Deep learning
DRAM1 promotes the stability of lysosomal VAMP8 to enhance autolysosome formation and facilitates the extravasation PMID 40595569
Metformin synergizes with rapamycin to inhibit the growth of pancreatic cancer in vitro and in vivo PMID 29434877
Eunicellin
MCE
The assessment on cross immunity with smallpox virus and antiviral drug sensitivity of the isolated mpox virus strain WIBP
Closantel
HB
CRBN ligand
PD
Rovatirelin 204386
含 CUB 结构域蛋白 1（CDCP1）基因
Synthesis of new pyrrolo[2,3
Metabolism/Immunity Dual
Targeting CDH11 with celecoxib and derivatives to suppress esophageal squamous cell carcinoma proliferation and invasion PMID 40460640
(Rac)
Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils PMID 27508871
P2Y1 antagonist 1 1555697
Csf2ra
Hepatocyte
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