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Cardiac microvascular functions improved by MSC
Synthesis and activity of dafachronic acid ligands for the C. elegans DAF
Alisol B 23
Analogs of penfluridol as chemotherapeutic agents with reduced central nervous system activity PMID 30389290
pVEC (Cadherin
De
anti
The Goldilocks paradigm comparing classical machine learning, large language models, and few
4,4'
Giparmen (吉帕孟)
MCE
Giparmen
Fusaric acid induces oxidative stress and apoptosis in human cancerous oesophageal SNO cells PMID 27956242
Ketogenesis Attenuates KLF5
Simultaneously detection of calcium and magnesium in various samples by calmagite and chemometrics data processing PMID 27341399
CRBN ligand
Conjugated dopamine in superfusates of slices of rat striatum PMID 7119800
Cefpiramide 70797
Chemerin
The positive feedback between ACSL4 expression and O
Glutamine deprivation confers immunotherapy resistance by inhibiting IFN
3
Aprocitentan mitigates doxorubicin
Δ9
MCE
Palmitoleic Acid Improves Metabolic Functions in Fatty Liver by PPARα
Alloferon 1 347884
Ectopic ATP synthase stimulates the secretion of extracellular vesicles in cancer cells PMID 37322056
4,4'
Synthesis and anti
Four novel insecticidal sesquiterpene esters from Celastrus angulatus PMID 17479422
Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide
Bisdionin C
TSR2 核糖体成熟因子（TSR2）基因
NC9 1352090
THE EFFECT OF MONOAMINE OXIDASE INHIBITORS ON GROWTH AND THE RAT TIBIA TEST PMID 14275679
Cytotoxic bistetrahydrofuran annonaceous acetogenins from the seeds of Annona squamosa PMID 22011319
RvE1/ChemR23 facilitates hematoma clearance and promotes M2 polarization of macrophages/microglia in intracerebral hemorrhage PMID 39892453
CRBN ligand
Milrinone attenuates thromboxane receptor
The epigenetic regulators EP300/CREBBP represent promising therapeutic targets in MLL
Ac
Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors PMID 22961667
Pseudorabies virus usurps non
JNJ
1,12
The proto
Rhein inhibits angiogenesis and the viability of hormone
LUF7346 1821638
Eicosapentaenoic acid activates RAS/ERK/C/EBPβ pathway through H
Tiprelestat 820211
The lysosome
(E)
MCE
Structural basis for full
Efficient airborne transmission of influenza D virus in ferret models and serological evidence of human exposure in Northeast China PMID 41069204
HUHS2002 1393102
Synthesis of camphor thiazole derivates from Dryobalanops aromatica and its bioactivity as antioxidants and antidiabetes against alpha glucosidase enzymes PMID 37867914
Lipid C3 2639634
Novel thiazolidinedione hybrids as cholinesterase inhibitors and targeting neuroblastoma design, synthesis, in vitro and in silico biological evaluations PMID 40834457
5
Efanesoctocog alfa 2252477
Current State of the Art and Prospects of T Cell
Cell density impacts the susceptibility to ferroptosis by modulating IRP1
nephrectomy
VU0360172 hydrochloride 1309976
3
CRBN ligand
3
Cannabisin F from Hemp ( Cannabis sativa) Seed Suppresses Lipopolysaccharide
HB
C
3,3'
Diquinoxalino[2,3
1,3,5
DDR1
PAM
Urolithin A Protects Ovarian Reserve Via Inhibiting PI3K/Akt Signaling and Preventing Chemotherapy
Targeting prominin2 transcription to overcome ferroptosis resistance in cancer PMID 34223704
β,β
3
IT
Sucrose Stearate 25168
Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti
Synthesis and glucose
Diperamycin 220766
SOS1
13
Pard6a
Targeting PKM2 improves the gemcitabine sensitivity of intrahepatic cholangiocarcinoma cells via inhibiting β
Adaptor complex
Hexoprenaline 3215
U
4,4'
5,5',5''
Dodecylamine
Two new biflavanoids from Selaginella trichoclada Alsto PMID 31841035
8
Betulinic Acid Enhances the Viability of Random
Effect of 1
3,3'
Cytokeratin 7 抗体 (YA950)（Cytokeratin 7 Antibody (YA950)）
CCL24
PKR Inhibition Prevents Neuroinflammation and Rescues Depressive
Synergistic Action of IL
Human Umbilical Cord
Snrpa Mouse Pre
Semaxinib (Standard) (司马沙尼 (标准品))
A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co
MRNIP condensates promote DNA double
Rationally Designed Highly Potent NKT Cell Agonists with Different Cytokine Selectivity through Hydrogen
Ubiquitin is directly linked via an ester to protein
The mechanism of NF
NSC 109555 15427
Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1) PMID 11958985
H
Ruzadolane 115762
HDAC3 modulates cancer immunity via increasing PD
SDF
Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells PMID 32756004
Single
Pyroptosis of chondrocytes activated by synovial inflammation accelerates TMJ osteoarthritis cartilage degeneration via ROS/NLRP3 signaling PMID 37625369
Brca1 is involved in tolerance to adefovir dipivoxil‑induced DNA damage PMID 31017265
Insulin Detemir 169148
1,5
Metabolic fate analysis of Huang
PIM and AKT kinase inhibitors show synergistic cytotoxicity in acute myeloid leukaemia that is associated with convergence on mTOR and MCL1 pathways PMID 24975213
4,4′
LB42708 226929
Inhibition of Stat3 activation suppresses caspase
3,4,5
IDH1
Secukinumab, a fully human anti
Dantrolene inhibits lysophosphatidylcholine
Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells PMID 18483302
Diosgenin glucoside 14144
9,10
Di(pyridin
Astrocytic VEGFA An essential mediator in blood
Targeting Colorectal Cancer with Conjugates of a Glucose Transporter Inhibitor and 5
Inhibitory effects of ONO
DNP
AsiDNA Treatment Induces Cumulative Antitumor Efficacy with a Low Probability of Acquired Resistance PMID 31362243
A Close Cognition of Charged Poly(l
The solvolysis of topotecan in alcohols and acetic anhydride PMID 21414778
Coibamide A induces mTOR
DB28 16296
Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation PMID 19717450
Platelet phosphatidylserine exposure and procoagulant activity in clotting whole blood
Tilmicosin and tylosin have anti
LEI105 1800327
C.I. Acid blue 40 6247
TC HSD 21 330203
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53
CAR T cells targeting tumor
Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting Del19/T790M/C797S Mutation PMID 35178183
Hepatocyte mitochondrial DNA activated store
FGF
TSLP 蛋白, Human (Biotinylated, HEK293, His
Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM PMID 34066147
A Zingerone Analog, Acetyl Zingerone, Bolsters Matrisome Synthesis, Inhibits Matrix Metallopeptidases, and Represses IL
Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release PMID 16203828
A role for G
Ginsenoside rg2 inhibits lipopolysaccharide
2,2'
Cartilaginous Metabolomics Reveals the Biochemical
Eupatoriochromene 19013
Silica sand, 1
Synthesis and anti
D
TNFSF4
TINF2 Human Pre
Increasing the Efficiency of CRISPR/Cas9
Novel vanilloid receptor
Noncovalent EGFR T790M/L858R inhibitors based on diphenylpyrimidine scaffold Design, synthesis, and bioactivity evaluation for the treatment of NSCLC PMID 34218082
Aurora kinase
Discovery of IRAK1/4/pan
EDIL3 蛋白, Human (HEK293, Fc)
Diabetes Primes Neutrophils for Neutrophil Extracellular Trap Formation through Trained Immunity PMID 38654733
IL
Preclinical characterization of tunlametinib, a novel, potent, and selective MEK inhibitor PMID 37808191
Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling pathway PMID 26253302
Structure
SDF Factor
Diiodoacetamide
Degradation of proteins by PROTACs and other strategies PMID 32082969
N
Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug
Sustained anti
Red
L
Strospeside 595
Targeting BRCA1
SpyCLIP an easy
Determination and validation of hupehenine in rat plasma by UPLC
Tick
Daporinad hydrochloride 2727965
[Sedating antihistamines
5
MCE
Therapeutic Efficacy of Esomeprazole in Cotton Smoke
ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection PMID 34874921
CD276/B7
Synergistic Effect of Flavonoids and Metformin on Protection of the Methylglyoxal
IL
MiR
Use of vanadate as protein
Natural gelatin / chitosan oligosaccharides / emodin eutectogels with multiple antibacterial effects for accelerated infected wound healing PMID 40628324
Supplementation of Mangiferin to a High
Development of an animal model for quantitatively evaluating effects of drugs on endometriosis PMID 3896862
The novel NTPDase inhibitor sodium polyoxotungstate (POM
Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide
RNA
In vitro and in vivo pharmacology of NXT629, a novel and selective PPARα antagonist PMID 28483457
ETC
Intracellular metabolic gradients dictate dependence on exogenous pyruvate PMID 40295877
Discovery and structural optimization of potent epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M/C797S resistance mutation for lung cancer treatment PMID 35447433
Antineoplastic agents. 548. Synthesis of iodo
DDR1
Integrated network pharmacology and metabolomics to investigate the effect and mechanism of nitidine chloride against cholangiocarcinoma PMID 40652810
连接多聚体 IgA 和 IgM 链（JCHAIN）基因
Lack of IL
The osmotically and histamine
Cyclin
Role of galectin
KAT13A/SRC1 抗体 (YA1735)（KAT13A/SRC1 Antibody (YA1735)）
Paeonol Protects Rat Heart by Improving Regional Blood Perfusion during No
Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging PMID 38718895
[Role of Hepatocyte Growth Factor in Wound Repair] PMID 30606395
Copper regulates rest
HY
Role of Heparan Sulfate in Vasculogenesis of Dental Pulp Stem Cells PMID 36281071
Evidence for cytochrome P450 3A4
In vitro evaluation of phosphocholine and quaternary ammonium containing lipids as novel anti
CD200R1 蛋白, Human (Biotinylated, HEK293, His
An acidic polysaccharide promoting GLP
Detection and quantification of the selective EP4 receptor antagonist CJ
Identification and biological activity of 6
PTPN5 Human Pre
MCE
Anticonvulsant activity of melatonin and its success in ameliorating epileptic comorbidity
An inhibitor of squalene epoxidase, NB
Jolkinolide E 54494
Enantiomers of HA
UEA I
Ulex Europaeus Agglutinin I (peroxidase) (UEA I (peroxidase)，过氧化酶结合的荆豆凝集素)
Ducloudine C (杜云英C)
Design, synthesis and biological evaluation of novel macrocyclic derivatives bearing aniline pyrimidine scaffolds as EGFR
Bioadhesive drug
In vitro activity of the novel β
Homodimerized cytoplasmic domain of PD
5,5'
Ameliorative Effects of Fermented Red Ginseng Extract on Muscle Atrophy in Dexamethasone
Gastrodia protects HT22 cells from damage caused by oxygen glucose deprivation and reperfusion through inhibiting ferroptosis PMID 40425648
Bitolterol mesylate a beta
Melatonin protects RPE cells from necroptosis and NLRP3 activation via promoting SERCA2
(E)
PSI
Targeting Two
Irisin protects against doxorubicin
Inhibition of NF
Synthesis of anti
The opioid antagonist, β
SB290157 trifluoroacetate (Standard)
Heparan sulfate a key regulator of embryonic stem cell fate PMID 23370908
Human immune organoids to decode B cell response in healthy donors and patients with lymphoma PMID 39506098
4
Inhibition of UCHL1 by LDN
Effect of propiomazine on plasma prolactin in the rat counteraction by L
Autocrine IGF
Regulatory effect of chemerin and therapeutic efficacy of chemerin‑9 in pancreatogenic diabetes mellitus PMID 31922216
真核翻译起始因子 2α 激酶 3（Eif2ak3）基因
Structure of the human histamine H1 receptor complex with doxepin PMID 21697825
NSC 601980
Cecropin P1, porcine
D
STAT3
Rfx3 Rat Pre
Increased endoplasmic reticulum stress response is involved in clopidogrel
IL13RA2
Il10rb
Desmethylbellidifolin From Gentianella acuta Ameliorate TNBS
Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase PMID 23521796
Mal
Somatostatin interneurons inhibit excitatory transmission mediated by astrocytic GABAB and presynaptic GABAB and adenosine A1 receptors in the hippocampus PMID 35775994
2,6
Immunoglobulin M An Ancient Antiviral Weapon
CCL21/CCR7 enhances the proliferation, migration, and invasion of human bladder cancer T24 cells PMID 25798926
2′
SIRT1 inhibits chemoresistance and cancer stemness of gastric cancer by initiating an AMPK/FOXO3 positive feedback loop PMID 32051395
Design, synthesis and 3D
Visilizumab induces apoptosis of mucosal T lymphocytes in ulcerative colitis through activation of caspase 3 and 8 dependent pathways PMID 18424236
1,7
Highly
Targeting of Helicobacter pylori thymidylate synthase ThyX by non
IRAK4 degrader in hidradenitis suppurativa and atopic dermatitis a phase 1 trial PMID 37957373
JC
Golgi α
Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti
Artesunate attenuates serum amyloid A
The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture PMID 28326781
Assembly Pathway Selection of Designer Self
Aripiprazole and dehydroaripiprazole plasma concentrations and clinical responses in patients with schizophrenia PMID 22020350
Biosynthesis of spinosyn in Saccharopolyspora spinosa synthesis of permethylated rhamnose and characterization of the functions of SpnH, SpnI, and SpnK PMID 20158237
The neuroendocrine control of the menstrual cycle PMID 6774388
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response PMID 22842901
Characterization of thien
4,10
Yttrium nitrate activates the oxidative stress
Sevoflurane induced neurotoxicity in neonatal mice links to a GSK3β/Drp1
Effect of soy flour on nutritional, physicochemical, and sensory characteristics of gluten
Identification of a novel circ_0001946/miR
Protease
Intrapulmonary Pharmacokinetics of Lascufloxacin in Healthy Adult Volunteers PMID 29339391
Discovery of new tetrahydroisoquinolines as potent and selective LSD1 inhibitors for the treatment of MLL
PREP inhibitor
CSE1L Human Pre
MCE
Long non
Nucleotide
Sudemycin D6 1510837
TK
Lofepramine
Cortistatin
Thymopentin
Deltasonamide 2 (TFA) 2235358
E
Linagliptin ameliorates acetic acid
Redesigning HVEM Interface for Selective Binding to LIGHT, BTLA, and CD160 PMID 32795404
TAL bHLH 转录因子 2（TAL2）基因
Mild Hypothermia Alleviates Complement C5a
P162
dimethyl 4,4'
5
Bifikafusp alfa 1957239
Ligustroside 35897
5,5'
KLF9
Schip1 promotes osteoclast differentiation via Taok1
ARI 3531
1,2
PI3K/mTOR Inhibitor
dASK1 3064086
Nuclear VPS35 attenuates NHEJ repair by sequestering Ku protein PMID 40484931
CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti
DNA 5
Pyrroloquinoline Quinone Alleviates Mitochondria Damage in Radiation
Methyl protodioscin 54522
N3
Inhibition of PDGF
Lactucopicrin Inhibits Cytoplasmic Dynein
(?)
Dual
Tetrakis(decyl)ammonium bromide 14937
Calpinactam 1205538
Dihydroartemisinin protects mice from CUMS
D
(3S,7S)
SC
4
Propargyl
Inhibition of nasopharyngeal carcinoma cell proliferation and synergism of cisplatin with silvestrol and episilvestrol isolated from Aglaia stellatopilosa PMID 27284293
Nilotinib counteracts thioacetamide
In Vivo Tracking of Fluorinated Polypeptide Gene Carriers by Positron Emission Tomography Imaging PMID 32940028
Comparison of the activities of zanamivir, oseltamivir, and RWJ
Bupropion morpholinol 357399
Flavoxate
Absinthin 1362
Butalamine hydrochloride 56974
S 18986 175340
Exendin
CXCL9 chemokine promotes the progression of human pancreatic adenocarcinoma through STAT3
Salicylate accumulation kinetics in man PMID 5044917
Formulation of carbenoxolone for delivery to the skin PMID 23545397
Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells PMID 34675185
Ustusolate A 1136611
Multi
Benzenemethanamine,N
Hypofucosylation of Unc5b regulated by Fut8 enhances macrophage emigration and prevents atherosclerosis PMID 36670464
Boc
A germline
KDM2A/7A
2
Paraspeckle Promotes Hepatocellular Carcinoma Immune Escape by Sequestering IFNGR1 mRNA PMID 33667716
4,4',4''
S
2
KBR 2822 126988
Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis
IL
Design, Synthesis, and Evaluation of Trivalent PROTACs Having a Functionalization Site with Controlled Orientation PMID 34878263
2
meso
5
Heneicosanoic acid (Standard)
米拖蒽醌甲磺酸盐 (标准品)
Rac
2,2'
Synthesis of novel pentacyclic triterpene
Phosphoenolpyruvate carboxykinase
The inositol monophosphatase inhibitor L
Diazepinomicin 733035
Binding characteristics of 3H
DF
The treatment role of Cyperus rotundus L. to triple
In Vitro and Clinical Evaluations of the Drug
Sn(iv) meso
Metabolism of the 18O
CRBN ligand
ETS1 抗体 (YA3800)(PBS only)（ETS1 Antibody (YA3800)(PBS only)）
(±)9(10)
Boc
MCE
Paeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt PMID 30941042
Discovery of a potent CDKs/FLT3 PROTAC with enhanced differentiation and proliferation inhibition for AML PMID 38878515
Drg1 Rat Pre
TWIST1+FAP+ fibroblasts in the pathogenesis of intestinal fibrosis in Crohn's disease PMID 39024569
Expression of the standard scorpion alpha
2,4
AT9283, a novel aurora kinase inhibitor, suppresses tumor growth in aggressive B
CRISPR/Cas9
1,4
Ginsenoside Rg3 attenuates angiotensin II
含 PDZ 结构域 1（PDZK1）基因
Effects of pyrazole partial agonists on HCA(2)
L
Aggressive Medulloblastoma
Polyketides with Anti
Effects of bile acids on hepatocellular signaling and secretion PMID 9626754
Binding site elucidation and structure guided design of macrocyclic IL
Inhibition of ATP
Development of Biaryl
2,3,4,5
Intact learning and memory in rats following treatment with the dual orexin receptor antagonist almorexant PMID 20631993
In vitro antitumour activity of orsellinates PMID 20355320
Thunalbene 220862
Bone mesenchymal stem cells based on matric hydrogels attenuate intervertebral disc degeneration by suppressing oxidative stress
(S)
6
The anti
β
(S)
CRBN ligand
Extracellular serine empowers epidermal proliferation and psoriasis
4
Carbocysteine restores steroid sensitivity by targeting histone deacetylase 2 in a thiol/GSH
2
Framycetin
MCE
Effects of alatrofloxacin, the parental prodrug of trovafloxacin, on phagocytic, anti
[Orn5]
Ferumoxytol promotes haematopoietic stem cell post
Development of an LC
Estrogen
Methyl (E)
Ferroptosis
3
Oleic acid protects saturated fatty acid mediated lipotoxicity in hepatocytes and rat of non
DMT
The long non
p
Novel coumarin
1, 4
Pitnot
单果牛栓藤提取物 (Connarus monocarpus L.)
SOX13 Human Pre
CD63 acts as a functional marker in maintaining hematopoietic stem cell quiescence through supporting TGFβ signaling in mice PMID 34363017
Crp Rat Pre
Asymmetric activation of the calcium
(S,R,S)
Modulation of circadian clock by crude drug extracts used in Japanese Kampo medicine PMID 34702865
A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model PMID 35665319
Design, synthesis and biological evaluation of 4
lncRNA HITT inhibits metastasis by attenuating Rab5
Gestodene
Ioxilan carbonate particles PMID 20641969
Chloridazon metabolite B1
CD47
Thiocolchicine 2730
Pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers PMID 2209453
CLCF1 promotes IL12Rβ2 proteolysis and limits Th1 differentiation PMID 40628045
Effects of 8
Sphingosine kinase 2 cooperating with Fyn promotes kidney fibroblast activation and fibrosis via STAT3 and AKT PMID 30251698
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression PMID 36462735
NAMPT regulates mitochondria and oxidative stress level for mouse early embryo development PMID 40320561
Dibenz[b,f]oxepin and Antimycobacterial Chalcone Constituents of Empetrum nigrum PMID 26473275
Interaction of polysialic acid with CCL21 regulates the migratory capacity of human dendritic cells PMID 19750015
Clavariopsin A 227083
Cyromazine
Design, synthesis and biological evaluation of combretastatin A
LIM 同源框 2（LHX2）基因
Drug Design and Synthesis of First in Class PDZ1 Targeting NHERF1 Inhibitors as Anticancer Agents PMID 30996786
Characterization in humans of 18F
In silico characterization of the interaction between LSKL peptide, a LAP
SLC7A11
Integrative network pharmacology, transcriptomics, and proteomics reveal the material basis and mechanism of the Shen Qing Weichang Formula against gastric cancer PMID 40155922
Evodiamine exerts anti
Clopidogrel treatment inhibits P2Y2
Targeting the ANXA8
16
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