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GSK682753A (Standard)
Inhibitory effects of grape seed extract on lipases PMID 14559324
Activation of PPARδ in bone marrow endothelial progenitor cells improves their hematopoiesis
MCE
6
Dibenzo(a,i)pyrene
AKT/PKB signaling navigating downstream PMID 17604717
Intracellular Vimentin Regulates the Formation of Classical Swine Fever Virus Replication Complex through Interaction with NS5A Protein PMID 37129496
Effect of renzapride on transit in constipation
Aziridine alkaloids as potential therapeutic agents PMID 19540628
Staphylococcus aureus extracellular vesicles induce apoptosis and restrain mitophagy
p
含 Rho 相关卷曲螺旋蛋白激酶 2（Rock2）基因
Establishment of two iPSC lines from healthy donor with heterozygous mutation in the SLC26A4 gene PMID 36126472
MPT0G211 2151853
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice PMID 30111643
MAGE 家族成员 E1（MAGEE1）基因
SGC
Levamlodipine (gentisate) 856256
Indatuximab ravtansine 1238517
CD27/TNFRSF7 蛋白, Rat (HEK293, Fc)
CAY10677 1443253
The roles of isomers of phytoene, phytofluene and zeta
HIV
Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol PMID 17178223
CD75/
HPOB
PR
Mosapride citrate dihydrate 636582
Targeting EP300 in diffuse large b
UDP 葡萄糖醛酸转移酶家族 1 成员 A4（UGT1A4）基因
LM
HERC5 induces podocyte injury in LN by mediated IRF3 ISGylation to promote the production and overactivation of IFN
8
The microtubule
VDLIN A Deep Learning
6,7
PROTAC KRAS G12D degrader 1 3033583
EZH2
Bioactive Indanes Design, synthesis and bioactivity investigation of 2,2
3,4
The Role of Type 1 Metabotropic Glutamate Receptors in the Generation of Dorsal Root Reflexes Induced by Acute Arthritis or the Spinal Infusion of 4
Effects of ANP receptor antagonists on ANP secretion from adult rat cultured atrial myocytes PMID 7900789
Exploiting the 2
Pleiotropic effects of a mitochondrion
MCE
In vitro antioxidant and anti
Discovery and Characterization of VU0529331, a Synthetic Small
Pelanserin 2208
Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate PMID 24900385
Synthesis of neolignans as microtubule stabilisers PMID 24457094
1
CD271 regulates osteogenic differentiation of ectomesenchymal stem cells via the RhoA/ROCK signaling pathway PMID 39826451
(Rac)
Postprandial exercise regulates tissue
FL118 A potential bladder cancer therapeutic compound targeting H2A.X identified through library screening PMID 39244972
CD28
Cytidine
N
MS1
Lamivudine
Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity PMID 15149689
Polo
ZLM
Gondoic acid 5561
Discovery of BRL 50481 [3
Initiation and perpetuation of rat adjuvant arthritis is inhibited by the anti
YTK
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de
TEF 转录因子，PAR bZIP 家族成员（TEF）基因
MCE
Mutants of human ACE2 differentially promote SARS
Levoleucovorin Calcium 80433
Technical Support
Estimating AChE inhibitors from MCE database by machine learning and atomistic calculations PMID 39561662
Targeting lysophospholipid acid receptor 1 and ROCK kinases promotes antiviral innate immunity PMID 34533996
Inhibition of S
New betulinic acid derivatives for bevirimat
Small Molecule Microarray Based Discovery of PARP14 Inhibitors PMID 27918638
New Hybrids Derived from Podophyllic Aldehyde and Diterpenylhydroquinones with Selectivity toward Osteosarcoma Cells PMID 29670695
Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu PMID 18076070
Tumour cell
Ferulic acid inhibits interleukin 17
(+)
O
Multidrug Efflux Pumps Attenuate the Effect of MGMT Inhibitors PMID 26379107
HMR 3339, a novel selective estrogen receptor modulator, reduces total cholesterol, low
Spatial Single Cell Analysis of Proteins in 2D Human Gastruloids Using Iterative Immunofluorescence PMID 37882990
Dimethyl trisulfide 3658
Thalidomide
Furazolidone
The role of the key autophagy kinase ULK1 in hepatocellular carcinoma and its validation as a treatment target PMID 31986961
HS103
ICAM
Impact of genetic background on nephropathy in diabetic mice PMID 16118394
BMS
Endoglycosidase S2 (D184M mutant) (EndoS2 D184M)
hsa
Endoglycosidase D (N322Q mutant) (EndoD N322Q)
NHI
Targeting the Wnt pathways for therapies PMID 26056595
Fmoc
Nitracrine 4533
In vitro anticancer activity of fluphenazine, perphenazine and prochlorperazine. A review PMID 32852120
SENP1
Antioxidant properties of neohesperidin dihydrochalcone inhibition of hypochlorous acid
Mouse Anti
Corticosterone stimulates synthesis of 2
Catalpol improves impaired neurovascular unit in ischemic stroke rats via enhancing VEGF
Quantitative Analysis of Bioactive Carbazole Alkaloids in Murraya koenigii (L.) from Six Different Climatic Zones of India Using UPLC/MS/MS and Their Principal Component Analysis PMID 34643999
MCE
c
BPTU, an allosteric antagonist of P2Y1 receptor, blocks nerve mediated inhibitory neuromuscular responses in the gastrointestinal tract of rodents PMID 27496690
Bromo
Sialyl
Bradykinin antagonists and thiazolidinone derivatives as new potential anti
Bisphenol A and several derivatives exert neural toxicity in human neuron
Fungicidal Activity of New Pyrrolo[2,3
Veratrole
Cross
2
胰岛素受体底物 2（IRS2）基因
NO2
MCE
Novel NPR2 Gene Mutations Affect Chondrocytes Function via ER Stress in Short Stature PMID 35455946
Antioxidant
Development of Benzothiazole
Structural and functional similarity between the Vgll1
Porphyromonas gingivalis outer membrane vesicles increase vascular permeability by inducing stress fiber formation and degrading vascular endothelial
Cho
Local H2 release remodels senescence microenvironment for improved repair of injured bone PMID 38012166
Development of a femtomolar
Antinociceptive effect of intracerebroventricular administration of glycine transporter
CRBN ligand
DSPE
ILK
Indirubin
Discovery of Ipragliflozin (ASP1941) a novel C
Distinguishing native trisaccharides having differential monosaccharide composition and linkage using PGC
ANXA1 inhibits trophoblast ferroptosis in preeclampsia by downregulating KISS1† PMID 40143407
In vitro antiplasmodial activity
Scyllatoxin, a blocker of Ca(2+)
Quizalofop
Norfluoxetine oxalate 107674
Epstein
New antitumor substances, BE
(3S,5S)
死亡相关蛋白 1（DAPL1）基因
Damsin and neoambrosin Two sesquiterpene lactones with affinity and different activity for PPAR and TRPA1 receptors PMID 39672074
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes PMID 38839979
TXNIP A key protein in the cellular stress response pathway and a potential therapeutic target PMID 37394581
Electroacupuncture stimulation induced M1/M2 polarization in white adipose tissues by activating the Y1 receptor in obese mice to reduce chronic inflammation PMID 40586350
ACT
Benzyl
DPC
N4
Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors PMID 31463953
Tonlamarsen sodium 2589926
Allosteric activators of glucokinase potential role in diabetes therapy PMID 12869762
Antitumor effect of hexa
Effects of proton pump inhibitors, esomeprazole and vonoprazan, on the disposition of proguanil, a CYP2C19 substrate, in healthy volunteers PMID 30845361
Anticancer agent 81 2820286
Hydroxychloroquine
Identification of potent c
Astemizole 68844
Alleviating role of ketamine in breast cancer cell
Synthesis, biological evaluation, and molecular modeling studies of new benzoxazole derivatives as PARP
Efficient synthesis of frutinone A and its derivatives through palladium
Triphenylbismuth
GI
Cycloartane
UAA crosslinker1
Sudan Black B, The Specific Histochemical Stain for Lipofuscin A Novel Method to Detect Senescent Cells PMID 27812872
Targeting native adult heart progenitors with cardiogenic small molecules PMID 22413910
11R(12S)
1,4
Inhibition of CXCR4 by LY2624587, a Fully Humanized Anti
Selective inhibition of M5 muscarinic acetylcholine receptors attenuates cocaine self
Tos
Protective effect of protopine on the focal cerebral ischaemic injury in rats PMID 17651307
ITGA5
Mesalazine impurity 8 118
(S,S,S)
Expression Ratios of the Antiapoptotic BCL2 Family Members Dictate the Selective Addiction of Kaposi's Sarcoma
Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function PMID 28077684
SJ10542 2789678
dCDP disodium (2'
Biological properties of aureobasidin A, a cyclic depsipeptide antifungal antibiotic PMID 8226319
The pivotal role of TBK1 in inflammatory responses mediated by macrophages PMID 23304064
Antiamnesic effects of tofisopam against scopolamine
Identification of zebrafish ortholog for human coagulation factor IX and its age
5,10,15,20
RTP4 Enhances Corneal HSV
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia PMID 32203080
Probing ion channel functional architecture and domain recombination compatibility by massively parallel domain insertion profiling PMID 34880224
Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide Withaferin A PMID 22188785
3
Fused
KIF18A
A human/mouse chimeric monoclonal antibody against CA125 for radioimmunoimaging of ovarian cancer PMID 7687520
17
Naftopidil 57149
Immunotoxicological effects of streptozotocin and alloxan in vitro and in vivo studies PMID 25573197
Knockdown of NFBD1/MDC1 enhances chemosensitivity to cisplatin or 5
Nerve Growth Factor (NGF) Encourages the Neuroinvasive Potential of Pancreatic Cancer Cells by Activating the Warburg Effect and Promoting Tumor Derived Exosomal miRNA
Alpha
信号素 3G（SEMA3G）基因
Generation of human induced pluripotent stem cell line from peripheral blood of patient with lymphedema
Inhibitory constituents of lipopolysaccharide
A Simple Fluorescent Probe for Biothiols Detection and Imaging of Living Cells In Vivo Based on a Hemicyanine Derivative PMID 40304845
Population pharmacokinetic/pharmacodynamic modelling of eplontersen, an antisense oligonucleotide in development for transthyretin amyloidosis PMID 35869634
Annexin A1 Attenuates Neutrophil Migration and IL
L
Igf2
Centriole evolution PMID 19196504
A constitutive pan
BE
ST6GAL1 promotes IBD B cell recruitment to the inflamed colon in a CD22
Acetyl
Aspirin relieves the calcification of aortic smooth muscle cells by enhancing the heat shock response PMID 34846265
Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide
Rnf31 Mouse Pre
NSC126188 31863
PA
Inhibition of S
Comparison of trastuzumab emtansine, trastuzumab deruxtecan, and disitamab vedotin in a multiresistant HER2
A combination of anti
New antitumor substances, BE
Structural insights into DNA recognition by AimR of the arbitrium communication system in the SPbeta phage PMID 31149347
Suppression of MPTP
Loss of tumor suppressor inositol polyphosphate 4
Gaq
Gai2
Phenolic compounds isolated from Morus nigra and their α
Pan
DNTTIP1 Human Pre
FPL13592
3
Tilorone increases glucose uptake in vivo and in skeletal muscle cells by enhancing Akt2/AS160 signaling and glucose transporter levels PMID 37012691
N
Antiparasitic agent
MCE
Remacemide hydrochloride a double
Diosgenin in Dioscorea spongiosa Suppresses Glycolysis
Fluorene
Activation of the alternative complement pathway modulates inflammation in thoracic aortic aneurysm/dissection PMID 38189133
Synthesis and characterisation of immunogens for the production of antibodies against small hydrophobic molecules with biosignature properties PMID 22093350
Piperazine
Fc ε 受体 Ia（FCER1A）基因
Tnfaip3 Mouse Pre
A new selective estrogen receptor modulator HMR
Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements PMID 28945785
(+)
The potential role of stem cell factor and its receptor c
Desmanthin 1
MCE
Secretin, canine 110786
GluOC promotes proliferation and metastasis of TNBC through the ROCK1 signaling pathway PMID 39054484
MCE
Oritavancin diphosphate 192564
Pulsed electromagnetic fields potentiate bone marrow mesenchymal stem cell chondrogenesis by regulating the Wnt/β
A non
NLR 家族，含 pyrin 结构域 1A（Nlrp1a）基因
Dracorhodin perchlorate regulates fibroblast proliferation to promote rat's wound healing PMID 29428295
MCE
NH
Contribution of alpha4beta1 integrin to the antiallergic effect of levocabastine PMID 18680729
Protein tyrosine phosphatase 1B regulates endothelial endoplasmic reticulum stress; role in endothelial dysfunction PMID 29894845
L2H2
The ansamycins hypolipidemic agents stimulating cholesterol removal by nonclassical mechanisms PMID 7806966
fenoldopam
Identification of an antibacterial compound, benzylideneacetone, from Xenorhabdus nematophila against major plant
A Phytochemical Constituent, (E)
Optimization of drug
Ikarisoside A inhibits inducible nitric oxide synthase in lipopolysaccharide
Natural resistance to infection with intracellular pathogens the Nramp1 protein is recruited to the membrane of the phagosome PMID 9034150
CNI
CHPG sodium salt 1303993
Synthesis and analgesic activity of some long
Modeling COVID
Herbicide safener
Using the yeast three
Scale
MCE
pancreatic carcinoma cells
Discodermolide analogues as the chemical component of combination bacteriolytic therapy PMID 15979874
Involvement of AMP
Targeted blocking of EGFR and GLUT1 by compound H reveals a new strategy for treatment of triple
MK
The SWI/SNF ATPase BRG1 facilitates multiple pro
(±)
Characterization of a novel, non
trans
Some pharmacological effects of the nematocide, morantel PMID 4352084
Synaptotagmin 7 is targeted to the axonal plasma membrane through γ
Revisiting CFTR inhibition a comparative study of CFTRinh
EG01377 dihydrochloride 2749438
Isoprenylated flavonoids from Morus nigra and their PPAR γ agonistic activities PMID 29427594
ID factors regulate the ability of Müller glia to become proliferating neurogenic progenitor
HLI98C
Infection control
MCE
Afatinib impurity 35 1637254
Azido
Marine Alkaloid Lepadins E and H Induce Ferroptosis for Cancer Chemotherapy PMID 37578947
Ensitrelvir 2647530
Loss of NFBD1/MDC1 disrupts homologous recombination repair and sensitizes nasopharyngeal carcinoma cells to PARP inhibitors PMID 30717758
Cyclopentane neuraminidase inhibitors with potent in vitro anti
tyramine
Toceranib (Standard) (托西尼布 (标准品))
Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 PMID 33868586
CD73
Azido
Estrogen
CYC682
PRMT6 deficiency or inhibition alleviates neuropathic pain by decreasing glycolysis and inflammation in microglia PMID 38402915
trans
(R)
Novel molecules that antagonize leukotriene B4 binding to neutrophils PMID 2837955
5'
Xenicane
RP
Dtx3l Mouse Pre
D,L
FBXL3
淋巴细胞抗原 6 家族成员 G6D（LY6G6D）基因
Spinal interleukin
DJ101 1803242
RG 7422
Crystal structure of (E)
Fbxo32 Mouse Pre
OP
6
Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice PMID 23891618
Pfkfb4 Mouse Pre
Briciclib sodium 865784
Dual
Carbetocin 37025
The anti
补体 C4A (罗杰斯血型)（C4A）基因
Erythrocarpines A
Non
CD73
5
MAPK
Validated stability indicating assay method of olaparib LC
PCGF1
11(Z),14(Z)
RG
GLPG0974 1391076
Amiodarone impurity 1 318267
Oncosis
The HDAC6/8/10 inhibitor TH34 induces DNA damage
Melatonin alleviates PM2.5
UNC13D Human Pre
The 5
Edar
Unc13d Mouse Pre
AGGF1 Human Pre
Wfs1 Mouse Pre
Toll样受体 4（Tlr4）基因
Toxicity study in juvenile rats with the α4β2 nicotinic acetylcholine receptor partial agonist CP
Synthesis and identification of α
Lansoprazole Exacerbates Pemetrexed
U
BMS229724
PRMT1 Confers Resistance to Olaparib via Modulating MYC Signaling in Triple
HC 258
Manganese(II) EOB
huMIF
Synthesis and cytotoxicity evaluation of some benzimidazole
Trihexyphenidyl PMID 30137772
emetine
Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons PMID 23215354
F860191
Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT
MDM2
MDM2
Propofol suppresses colorectal cancer development by the circ
Aldehyde
Dodoviscin a inhibits melanogenesis in mouse b16
Interferon signal transduction of biphenyl dimethyl dicarboxylate/amantadine and anti
Induction of enantio
Tizanidine is mainly metabolized by cytochrome p450 1A2 in vitro PMID 14998432
Selective Killing of RAS
TCN 238
Augmenting NK cell
Tetrahydrocurcumin targets TRIP13 inhibiting the interaction of TRIP13/USP7/c
HDM201
Microwave
Development of highly active anti
COTC 57449
MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy PMID 21118963
The novel use of a heterozygous knockout mouse for embryofetal development assessment of a glucokinase activator PMID 24753370
Dual
Depletion of SENP1
Discovery of cycloalkyl
Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus PMID 29167582
Pharmacokinetics and metabolism of allopurinol riboside PMID 2029827
Efficacy Evaluation and Mechanism Study of Nonantibiotic Nanoplatform for Clearing MRSA PMID 40478174
Lasp1 Mouse Pre
Repurposing Cardiac Glycosides to Potentiate CD47 Blockade through Calreticulin
Ultrafine black carbon caused mitochondrial oxidative stress, mitochondrial dysfunction and mitophagy in SH
Butobendine 55769
PLEKHA4 is transcriptionally regulated by HOXD9 and regulates glycolytic reprogramming and progression in glioblastoma via activation of the STAT3/SOCS
Long non
chitosan
Qingre Huoxue Decoction Alleviates Atherosclerosis by Regulating Macrophage Polarization Through Exosomal miR
Panax notoginseng saponin R1 modulates TNF
Porcine respiratory coronavirus in 10 provinces of China Molecular epidemiology, genetic diversity, and pathogenesis of the isolated PRCV/NM strain PMID 40411991
TNF
Ubiquitin specific protease 5 negatively regulates the IFNs
Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer PMID 32396863
BMS
SAHA
Exacerbation of neuronal senescence after spinal cord injury Role of the macrophage
TKL002
mmu
MCUF
MCE
Butanol isomers exert distinct effects on voltage
Novel antiviral activity of l
SAHA
Discovery of novel covalent inhibitors of DJ
Lymphatic Metastasis of Esophageal Squamous Cell Carcinoma The Role of NRF2 and Therapeutic Strategies PMID 40507333
Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders PMID 38569115
Chronic Intermittent Hypoxia
Crystal structure of Leishmania mexicana cysteine protease B in complex with a high
Human induced pluripotent stem cell line (FDHSi005
6PPD
BMS
Prothracarcin 81542
POP
DJ
Prothracarcin
Nimbolide 25990
Optimization of activity
TFIIH
RSS 0680
HCC1395
Bioinspired hierarchical fiber
PARD6B Human Pre
PGE 9262932 221221
A new 9,11
ONECUT2 Human Pre
Synthesis of natural phaeosphaeride A derivatives and an in vitro evaluation of their anti
ELQ
A selective cytotoxic adenovirus vector for concentration of pluripotent stem cells in human pluripotent stem cell
Physakengose G induces apoptosis via EGFR/mTOR signaling and inhibits autophagic flux in human osteosarcoma cells PMID 29655686
LCA5 Human Pre
Integrative analysis of bulk and single
Exploring the Potential of Cyclic Peptidyl Antitumor Agents Derived from Natural Macrocyclic Peptide Phakellistatin 13 PMID 38990190
Primordazine B 339337
Limazepines A
XCL1
Tekt1 Mouse Pre
Effects of sesquiterpenes and triterpenes from the rhizome of Alisma orientale on nitric oxide production in lipopolysaccharide
Protective effects of higenamine combined with [6]
Synthesis and evaluation of analogues of (Z)
Perindopril
Sphingosine
Structure
High
Vazegepant 1337918
EGF
Production of cis
Modification of cellular DNA by synthetic aziridinomitosenes PMID 26541587
DMRT3 Human Pre
MCE
Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G
Gatorbulin site
NA
Pharmaceutical properties of related calanolide compounds with activity against human immunodeficiency virus PMID 9724557
nbi
PAQR7 Human Pre
Two new monoterpenoid indole alkaloids from Alstonia rostrata PMID 28768429
MCE
IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II PMID 21359112
Sex
Diacetolol
Generation of neural organoids for spinal
Aristolactam A IIIa 97399
Dexamethasone induced apoptosis of A549 cells via the TGF
Involvement of the TGFβ1/Smad2/MMP3 signaling pathway in SB431542
TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro PMID 28420207
Pilose antler extract restores type I and III collagen to accelerate wound healing PMID 36931024
Challenges in Therapeutically Targeting the RNA
TGF
Cytip Mouse Pre
ActivinA activates Notch1
Dose
Targeting FDX1 by trilobatin to inhibit cuproptosis in doxorubicin
Epox
MAT
JCS 1
Remodeling oncogenic transcriptomes by small molecules targeting NONO PMID 36864190
Role of matrix metalloproteinase
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