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An anti
NOTA
In vitro expression of NGN3 identifies RAB3B as the predominant Ras
BAY32
Lersivirine 473921
Selective PARP
胃酸分泌异常 (Abnormal Gastric Acid Secretion)
New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis PMID 16284631
Follistatin expressed in mechanically
persephin（PSPN）基因
Inhibitors of lipid phosphatidate receptors N
Breviscapine regulates lipid metabolism of microglia via the ADORA1/PPARα/ACOX1 pathway to promote spinal cord injury recovery PMID 40628044
Isolation and characterization of peptide YY (PYY), a candidate gut hormone that inhibits pancreatic exocrine secretion PMID 6953409
TGF beta 抗体 (YA5387)（TGF beta Antibody (YA5387)）
Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation PMID 20158204
RAF1 蛋白, Human (Y340D, Y341D, sf9, GST)
Aspergillusidone D 1454585
P3FI
Differential induction of IgE
Pipoxolan inhibits proliferation of HL
Classic and new strategies for the treatment of advanced melanoma and non
MCE
PC
Expression of programmed death ligand 1 (PD
Effects of anisotropine methylbromide (Valpin) and its mixture with sulpyrine on vocalization response and spasm of intestine induced by acetylcholine in dogs PMID 4538412
2
Allysine
Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice PMID 10368126
Synthesis and evaluation of rifabutin analogs against Mycobacterium avium and H(37)Rv, MDR and NRP Mycobacterium tuberculosis PMID 19119013
ATL801
Study of stereoselective synthesis of (+/
Lrp5
TRPC3/6
Bakuchiol 10309
Discovery and Optimization of Novel Apo
Lansoprazole N
Porphyrins with combinations of 4
Rapamycin ameliorates immune
Hyperglycemia
Cabazitaxel Remains Active in Patients Progressing After Docetaxel Followed by Novel Androgen Receptor Pathway Targeted Therapies PMID 24837187
2
Carprazidil 68020
Cimetidine hydrochloride 70059
Effects of curcumin on oxidative stress, inflammation and apoptosis in L
The specific dopamine uptake inhibitor GBR 12783 improves learning of inhibitory avoidance and increases hippocampal acetylcholine release PMID 9774732
Potent bacteriolytic activity of ritipenem associated with a characteristic profile of affinities for penicillin
Design, synthesis and in vitro activity of 1,4
PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non
Kahweol inhibits lipid accumulation and induces Glucose
MRS4608
ElteN378 1421366
A Safe, Effective, and Economical Protocol for Rabbit Vertebral Screw Insertion PMID 40920648
FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2
The small organic compound HA14
Characterisation of ACTH peptides in human skin and their activation of the melanocortin
Activities of Oxadiazole Antibacterials against Staphylococcus aureus and Other Gram
Pip
Role of neuropeptide Y Y₁ and Y₂ receptors on behavioral despair in a rat model of depression with co
YAP activation in Müller cells alleviates oxidative stress in the rat retina after intravitreal injection with methylglyoxal PMID 40058941
MCE
1,2,3,4,6
Xestospongin C is a potent inhibitor of SERCA at a vertebrate synapse PMID 12127061
The role of TGF
The tandem affinity purification (TAP) method a general procedure of protein complex purification PMID 11403571
Emergence of multidrug resistance and genomic analysis of azithromycin
Characterization of a mouse second leukotriene B4 receptor, mBLT2 BLT2
Pks13
Na+,K(+)
1
In vitro evaluation and molecular docking of QS
Pseudouridine 5'
Adenomycin 76174
The Immunostimulative Effect and Mechanisms of a Novel Mouse Anti
Budesonide acid
Panaxadiol inhibits programmed cell death
Design, synthesis, and bioactivity evaluation of novel amide/sulfonamide derivatives as potential anti
AChE inhibitory activity of N
Ethyl
Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers 73049
Identification of Novel Mast Cell Activators Using Cell
Differential inhibition of activity, activation and gene expression of MMP
Structure, activities and biomedical applications of human butyrylcholinesterase PMID 19508180
枪刀药提取物 (Hypoestes purpurea (L.) R. Br.)
脂氧合酶
Ursodeoxycholic acid methyl ester
SCH 602539, a protease
Structure of human PNP complexed with ligands PMID 15983407
MCE
Cyclic AMP signalling PMID 11493633
Raleukin
Leukemia inhibitory factor receptor is structurally related to the IL
Re
Anti
Enzymatic synthesis of peptides on a solid support PMID 19194581
Sbds
Preclinical safety profile of disitamab vedotin：a novel anti
Targeting Myeloid Leukemia
Molecular glue degrader for tumor treatment PMID 39759140
1
An enzymatic ratiometric fluorescence assay for 6
Purification and comparative neurotoxicity of the trichothecenes satratoxin G and roridin L2 from Stachybotrys chartarum PMID 20077192
Rescue of High Glucose Impairment of Cultured Human Osteoblasts Using Cinacalcet and Parathyroid Hormone PMID 36754901
Block of voltage
The discovery of anthranilic acid
Tumor
BEZ235 reduction of cisplatin resistance on wild
MCE
Discovery of an efficacious KDM5B PROTAC degrader GT
A tandem activation of NLRP3 inflammasome induced by copper oxide nanoparticles and dissolved copper ion in J774A.1 macrophage PMID 33485222
Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate
人腹内侧前额叶皮层/前扣带皮层
CTRB1 蛋白, Human (HEK293, His)
MAO
Ester Prodrugs of IHVR
INT
Promazine
Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives Discovery of A Potent P
Mizagliflozin, a selective SGLT1 inhibitor, improves vascular cognitive impairment in a mouse model of small vessel disease PMID 34586752
Ubiquicidin
UR
JNJ
Dok1
Increased yield of gelatin coated therapeutic cells through cholesterol insertion PMID 32491263
Comprehensive multiomic analysis of extracellular vesicles from Mycoplasma bovis
Living Macrophage
GCAP1 蛋白, Human (sf9)
Tos
Coumberone 878019
Intratumoral delivery of IL
6
Scytalol D 208183
Synthesis, antimicrobial, anticancer evaluation and QSAR studies of 6
PPP1R1A 抗体 (YA3109)（PPP1R1A Antibody (YA3109)）
钙粘素 8（CDH8）基因
AS19 1000578
Small
丁香酚
UC
MCE
Ro 23
YSA
Givosiran sodium 1639325
Discovery of novel spiro 1,3,4
L
Iodine
4,5
Nickel(0)
Synergistic combination of isogarcinol isolated from edible fruits of Garcinia multiflora and dexamethasone to overcome leukemia glucocorticoid resistance PMID 38039755
HP1 recruits activity
The inhibitory effect of paeoniflorin on reactive oxygen species alleviates the activation of NF
Discovery of novel INK4C small
Duocarmycin
RBFOX2 Human Pre
Disruption of CTCF Boundary at HOXA Locus Promote BET Inhibitors' Therapeutic Sensitivity in Acute Myeloid Leukemia PMID 33057942
CRBN ligand
Cited2 modulates TGF
Synthesis and neuroprotective activity of bergenin derivatives with antioxidant activity PMID 12659764
2
AM
UK
SCY
Genistin A Novel Potent Anti
Neuroprotective Effects of Vapreotide on Tau Transfection
Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI
Cox17
hsa
Prevention of HIV
ML 229
ML 189
Structure
Zinc
Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse PMID 11702953
PI3K
P276
Improved anticancer and antiparasitic activity of new lawsone Mannich bases PMID 27912173
Exploratory Investigation of Zinc
SC48274
Monoamine oxidase
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease PMID 12149470
DZW
RAD
Near
TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling PMID 9537512
Cd19
Discovery of novel hybrids of diaryl
Thienyl and thiazolyl acyclic analogues of 5
Cationic PAMAM dendrimers as pore
Overcoming Nanosilver Resistance Resensitizing Bacteria and Targeting Evolutionary Mechanisms PMID 39739341
4
Porphyromonas gingivalis potentiates stem
miR
Crystal Structures of Potent Dimeric Positive Allosteric Modulators at the Ligand
Activation of serum response element
MCE
Capn2
Structure
Novel imidazo[1,2
The Selective 3
SMYD2 targets RIPK1 and restricts TNF
Blockade of the NLRP3/caspase
A photoactivatable prodrug strategy toward spatially targeted inhibition of POLRMT for anticancer therapy PMID 41478007
Targeting bone marrow mesenchymal stromal cells
hsa
Methyl isoferulate 16980
GABAA receptor agent 5 1808389
Proof
Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction PMID 35238867
From death receptor to reactive oxygen species and c
Increased hepcidin in hemorrhagic plaques correlates with iron
赖氨酸脱甲基酶 6B（KDM6B）基因
Rac 家族小 GTPase 3（RAC3）基因
含 ATPase 家族 AAA 结构域 2（ATAD2）基因
含 CUE 域 2（CUEDC2）基因
单
Synthesis and biological evaluation of oxindole linked indolyl
Design, synthesis and biological evaluation of Nucleosidic CD99 inhibitors that selectively reduce Ewing sarcoma viability PMID 36917882
In vitro, in vivo and in silico analysis of the anticancer and estrogen
Antihypertensive effects of CI
Ranitidine bismuth citrate 128345
Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma PMID 26061748
2,6,9
Novel photochemistry of leuco
I
Anti
The extracellular entrance provides selectivity to serotonin 5
Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit
Axinysterol
Visepegenatide 2641081
In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended
Detection of humoral response in patients with glioblastoma receiving EGFRvIII
Identification of an immunodominant IgE epitope of Der p 39, a novel allergen of Dermatophagoides pteronyssinus PMID 35600837
Empagliflozin treatment rescues abnormally reduced Na currents in ventricular cardiomyocytes from dystrophin
Pisd
Deltorphin 119975
Apoptosis inducer 8 2470024
Succinate Facilitates CD4+ T Cell Infiltration and CCL1 Production to Promote Myofibroblast Activation and Renal Fibrosis in UUO Mice PMID 40538778
23
NFKB 抑制因子 β（NFKBIB）基因
Efficacy and tolerance of fluocortin butyl administered twice daily in adult patients with perennial rhinitis PMID 3884690
Human alpha
Methanone, 1,1′
p53
Antifungal activity of some mono, bis and quaternary Mannich bases derived from acetophenone PMID 11215330
Ligustrazine activate the PPAR
Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes PMID 23953944
Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice PMID 29883783
Prevention of graft
Highly sensitive ultra
Production of AFM wedged cantilevers for stress
Studies of the synthesis of all stereoisomers of MG
CXCR4 inhibitors could benefit to HER2 but not to triple
Identification of mosquito sterol carrier protein
Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin
Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin
Hexadecyl oleate 22393
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging PMID 36762391
Aflatoxin G1 induced TNF
Sim
CDC 样激酶 1（Clk1）基因
Adavosertib (Standard) (AZD1775 (Standard))
Anti
GI
Crotonylation of MCM6 enhances chemotherapeutics sensitivity of breast cancer via inducing DNA replication stress PMID 39477811
Pyr3 1160514
Ror1
Edn1
Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways PMID 15556627
Curcumin triggers the Wnt/β
Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation PMID 38305738
AHR
Dipiproverine 117
Modeling Human Thyroid Development by Fetal Tissue
Spizofurone 72492
Mycobacterium tuberculosis Zinc Metalloprotease
The effect of rapamycin, NVP
Efficient Synthesis of Icetexane Diterpenes and Apoptosis Inducing Effect by Upregulating BiP
信号转导衔接分子（STAM）基因
ZL 1102
1,3
The water
Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys PMID 3609545
MCE
NADPH 氧化酶 5（NOX5）基因
Actr8
Discovery of new pyridine
Benzophenone C
Short communication differences between macrophages and dendritic cells in the cyclic AMP
Dipiproverine hydrochloride (LD
Pantoprazole impurity 26 (Standard)
肌肉蛋白（MSC）基因
MCE
Proteome
Establishment and transcriptomic characteristics of radio
Msc
Mal
Differential inhibition of T
Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF
4
Capsaicin
CP
Ppp2r1b
Liver fibrosis and repair immune regulation of wound healing in a solid organ PMID 24566915
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition PMID 18086313
Design, synthesis and biological evaluation of hydroxycinnamoylamides derivatives as potent glucosidase inhibitors PMID 41576897
Slc7a10
Niaprazine 27367
S
Baicalin alleviates pathological changes in Alzheimer's disease comorbid with type 2 diabetes Targeting metabolic dysregulation and neuroinflammation PMID 40759295
碳酸酐酶 2（Car2）基因
METTL14
MCE
突触核蛋白 α（Snca）基因
Synthesis and biological evaluation of 1,2,3
Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy PMID 39093701
Antihypertensive peptides derived from bovine casein and whey proteins PMID 18183935
Harmaline and harmalol inhibit the carcinogen
CP
Halofantrine hydrochloride 36167
共激活因子相关精氨酸甲基转移酶 1（Carm1）基因
A peptide triple agonist of GLP
Magnetic liposome as a dual
Structure
Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors PMID 24040486
Modulating Mineralocorticoid Receptor with Non
SOX1
Thrombospondin 1 Mediates Autophagy Upon Inhibition of the Rho
Btd
Calcitriol attenuates weight
HBT1 489408
Crystal structure of maltose phosphorylase from Lactobacillus brevis unexpected evolutionary relationship with glucoamylases PMID 11587643
1
Small
A comparative study of the redox
NAD
C.I. Mordant Orange 29
MrgprX2 antagonist
eEF2K degrader
Nfat5
Physiologic, Metabolic, and Toxicologic Profile of 1,3
Arcapillin 83162
RIP2 kinase inhibitor 2 1581270
Vps29
Targeting SMYD2 inhibits prostate cancer cell growth by regulating c
Loss of the DNA repair protein, polynucleotide kinase/phosphatase, activates the type 1 interferon response independent of ionizing radiation PMID 39087523
Discovery of novel pyrazolo[1,5
MAO
Optimisation of imidazole compounds as selective TAAR1 agonists discovery of RO5073012 PMID 22795332
p
Inhibitory Effect of Gardenoside on Free Fatty Acid
Surfactant Protein D in Respiratory and Non
Autophinib (Standard)
Pyrazinecarboxylic acid
1,4
High
MCE
Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus
Neuropeptide W
Inhibitors of Brassinosteroid Biosynthesis and Signal Transduction PMID 31795392
Disparate SAR data of griseofulvin analogues for the dermatophytes Trichophyton mentagrophytes, T. rubrum, and MDA
ATX inhibitor 20 2691937
Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production PMID 30017246
ATM/ATR
Therapeutic targeting of hepatic ACSL4 ameliorates NASH in mice PMID 34510514
Abivertinib maleate dihydrate
Ursodeoxycholic acid loaded dual
MCE
N
MCE
FNIII14 206536
The FABD domain is critical for the oncogenicity of BCR/ABL in chronic myeloid leukaemia PMID 38849885
BMS
EC144 is a potent inhibitor of the heat shock protein 90 PMID 22938030
Molecular and crystal structure of spiculisporic acid and correlation with the surface activity PMID 24088517
Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3 PMID 24641103
Penicillin G procaine hydrate 6130
PF 00337210
The antagonists but not partial agonists of glucocorticoid receptor ligands show substantial side effect dissociation PMID 21558312
L
Fbxl5
Induction of apoptosis and regression of spontaneous dog melanoma following in vivo application of synthetic cyclin
Mechanisms Underlying Dopaminergic Regulation of Nicotine
Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice PMID 39002758
MCE
Neuromelanin in Parkinson's Disease Tyrosine Hydroxylase and Tyrosinase PMID 35456994
MCE
Tubulin
DFHBI
Synthesis of norbiotinamine and its derivatives PMID 8983350
NSC
Effect of a novel NK1 receptor selective antagonist (NKP608) on citric acid induced cough and airway obstruction PMID 14643166
SARS
Lck Inhibitor III 1188890
Discovery of LHRH and development of LHRH analogs for prostate cancer treatment PMID 28449236
Enhancement of motility and acrosome reaction in human spermatozoa differential activation by type
NBD
IDH1 Inhibitor 9 3037967
Discovery and SAR study of highly selective and potent 1,2,4
Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis PMID 26713110
Isoscoparin
Ganoderic acid H 98665
MCE
Inhibition of rat mononuclear cell leukemia by corn oil gavage in vivo, in situ and immune competence studies PMID 8313508
Design and evaluation of histidine
Photolumazine I 29161
Synthesis and evaluation of acyl
Thrombospondin
MCE
Nanocrystal biolabels with releasable fluorophores for immunoassays PMID 15228335
Regulation of energy metabolism by long
Design, synthesis and biological evaluation of novel quinazolinedione derivatives as non
Head activator neuropeptide 79943
Enteropeptidase, a type II transmembrane serine protease PMID 19482641
3
Aminopyridine
TK
Tiropramide hydrochloride 53567
Pharmacokinetics and Safety Study of HN0037, a Novel Anti
LILRA5/CD85f 蛋白, Human (HEK293, His
A tumor
Endothelin
Multicolor FRET silica nanoparticles by single wavelength excitation PMID 16402792
Fibrinogen regulates the expression of inflammatory chemokines through NF
Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors PMID 38556760
RS 39604 a potent, selective and orally active 5
Pharmacokinetic and pharmacodynamic properties of the novel basal insulin Fc (insulin efsitora alfa), an insulin fusion protein in development for once
Preclinical Pharmacokinetics and in vitro Metabolism of FHND5071, a Novel Selective RET Kinase Inhibitor PMID 37528327
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors PMID 26745812
WR
Topical Application of Butyl Flufenamate Ointment Promotes Cranial Defect Healing in Mice by Inducing BMP2 Secretion in Skin Mesenchymal Stem Cells PMID 36429048
ACTB Loss
Structural basis for CCR6 modulation by allosteric antagonists PMID 39217154
LY 2033298 886047
Glucose
Neutrophil
TMS 24144
Application of plasma circulating KRAS mutations as a predictive biomarker for targeted treatment of pancreatic cancer PMID 38348576
PTGES3 Human Pre
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs PMID 19680262
MCE
(rel)
Pro
Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer PMID 26101715
Hellebrigenin induces oral cancer cell apoptosis by modulating MAPK signalling and XIAP expression PMID 38044583
Combining the tail and the ring approaches for obtaining potent and isoform
Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea PMID 30668547
CDD
Observations on the pharmacology of thalicminine, an oxyaporphine alkaloid from Thalictrum isopyroides PMID 1905248
Single
PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) (Polyvinyl alcohol (Mw 145000, 99+% hydrolyzed, ~3300 polymerization)，聚乙烯醇(Mw 145000, 99+% hydrolyzed, ~3300 polymerization))
Efficacy of postinfection treatment with anti
蛋白酪氨酸激酶 6（PTK6）基因
Antibiotic Substances from Basidiomycetes IX. Drosophila Subtarata. (Batsch Ex Fr.) Quel PMID 16589145
Design, Synthesis, and Biological Evaluation of Oligosaccharides Derived from Pleurotus ostreatus Polysaccharide as Potential Neuroprotective Agents PMID 41498360
Pold3
CRISPR/Cas9
Antiprotozoal Isoprenoids from Salvia hydrangea PMID 30565934
PROTAC
Integrin alpha V beta 8 蛋白, Mouse (HEK293, His)
Characterization of LY2775240, a selective phosphodiesterase
In Vitro Utilization Characteristics of Maltobionic Acid and Its Effects on Bowel Movements in Healthy Subjects PMID 34429693
CRBN ligand
On the mode of action of thrombin
Design and synthesis of new 1,3,4
Folate analogues as inhibitors of thymidylate synthase PMID 3470522
Potent and selective bivalent inhibitors of BET bromodomains PMID 27775716
Fmoc
Discovery and Characterization of Selective and Ligand
Cognitive protection of sinomenine in type 2 diabetes mellitus through regulating the EGF/Nrf2/HO
MCE
New Mitochondria
内皮素 1（EDN1）基因
Determination of ticagrelor and two metabolites in plasma samples by liquid chromatography and mass spectrometry PMID 20688583
CRBN ligand
ARN14974 1644158
Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease PMID 21412423
N
N
N1
Two in one Acceptor engineering strategy to construct efficient type I aggregation induced emission photosensitizer for photodynamic antitumor and antibacterial therapy PMID 40902511
β
Design, synthesis, and evaluation of 4(1H)
Lactobionic Acid as a Potential Food Ingredient Recent Studies and Applications PMID 31237977
MCE
Novel GPER Agonist, CITFA, Increases Neurite Growth in Rat Embryonic (E18) Hippocampal Neurons PMID 35353510
Efficacious Preclinical Repurposing of the Nucleoside Analogue Didanosine against COVID
Design, Synthesis, and Pharmacological Characterization of a Neutral, Non
l
Artanin 96917
SB
Butyrolactone
白介素 1β（IL1B）基因
CXC
DL
Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic αvβ6 Integrin Inhibitors PMID 39269712
MCE
GW 610 872726
A novel class of monoglutamated antifolates exhibits tight
MCE
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