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生物活性分子最近更新
MCE
(S,R,S)
MCE
2
N
Artificial intelligence
A novel, species
Hepatoprotection of silymarin against thioacetamide
Effective oral delivery of Exenatide
Autonomic and hemodynamic effects of a new selective dopamine agonist, CHF1035, in patients with chronic heart failure PMID 11669407
Methyltetrazine
mASC
IGF
Mesothelin 蛋白, Human (303a.a, HEK293, His)
Development of Potent MALT1 Inhibitors Featuring a Novel 2
NSC
MCE
Dazopride 70181
小泛素样修饰符 3（SUMO3）基因
PF
4
L
Silibinin, a commonly used therapeutic agent for non
Synthesis, Preclinical Evaluation, and a Pilot Clinical PET Imaging Study of 68Ga
YM90K pharmacological characterization as a selective and potent alpha
DPT Human Pre
Dimethoxycurcumin
Vericiguat impurity
Aminopeptidases structure and function PMID 8440407
SB
Heptylbenzene
TAPSO sodium 105140
Tianeptine, an atypical pharmacological approach to depression PMID 30612921
含磷脂酰肌醇特异性磷脂酶 CX 结构域 3（PLCXD3）基因
Reduction in susceptibility to natural killer cell
Green Tea Epigallocatechin
HeLa
Rab37 Promotes Endothelial Differentiation and Accelerates ADSC
1'
MCE
Aconitic acid 499
Down
LY
LMAN2L 蛋白, Human (HEK293, His)
The HA tag is cleaved and loses immunoreactivity during apoptosis PMID 17264856
GLIS 家族锌指 1（GLIS1）基因
MCE
Deoxyelephantopin 29307
SB
Dihydrorhodamine 123 (Standard) (二氢罗丹明123 (标准品))
Design, synthesis and biological evaluation of cinnamic acid derivatives with synergetic neuroprotection and angiogenesis effect PMID 31541868
ADHP (Standard)
H
HR
Zanamivir
Phosphatase, Escherichia coli
Triptohypol E
Spint2 Rat Pre
KNG1 Human Pre
TSG101 Human Pre
Spink2 Rat Pre
Ac
PGM2 蛋白, Human (His)
Dpys Rat Pre
Chloroplast rRNA blocker
Tubeimoside
Guraxetan
MCE
OSBPL7 Human Pre
CLEC3A Human Pre
NANOS3 Human Pre
ARID1A Human Pre
Doxycycline calcium 94088
Trimethoprim
2
KHNYN Human Pre
Clindamycin Hydrochloride
Tnfsf14 Rat Pre
NTN1 Human Pre
(±)
N
Fam162a Rat Pre
CRBN
Phenylaminojuglone AJ
NFATC4 Human Pre
Gallic acid hydrate 5995
A novel class of antagonists for the FFAs receptor GPR40 PMID 19818732
Duloxetine clinical pharmacokinetics and drug interactions PMID 21366359
阿利新蓝染色试剂盒 (pH 1.0) (Alcian Blue Staining Solution (pH 1.0))
5
JQ
6
5(6)
MCE
Neuropeptide Precursor VGF Promotes Liver Metastatic Colonization of Gαq Mutant Uveal Melanoma by Facilitating Tumor Microenvironment via Paracrine Loops PMID 39422674
Quarfloxin 865311
Galloyl esters of trans
Tetrabutylammonium (dihydrogen trifluoride) (Tetrabutylammonium (dihydrogen trifluoride))
5
SARS
Development of p300
Fmoc
MCE
Glial cell line derived neurotrophic factor (GDNF) induces mucosal healing via intestinal stem cell niche activation PMID 39610047
hsa
MCE
Anti
Methylamino
MCE
(S)
Cholyl
Discovery of an orally active small
(+)
The SNAP
PD
CRBN ligand
Bipolaricin R
FITC
Atm
Effect of Epigallocatechin
Design, Synthesis, and Anti
Soluble human IL
Limited tumor
Rodent Gnawing Blocks (啮齿类磨牙棒)
SF2523 (Standard)
β
Disulfiram Improves Fat Graft Retention by Modulating Macrophage Polarization With Inhibition of NLRP3 Inflammasome
voriconazole impurity 1
P4hb
4
Mal
MCE
MCE
Nppa
NAD+ metabolism and its roles in cellular processes during ageing PMID 33353981
内质网凝集素 1（ERLEC1）基因
Irisin attenuates acute lung injury by suppressing the pyroptosis of alveolar macrophages PMID 36896789
Amino
1,2,3,4
Pyrithiamine hydrobromide (吡啶硫胺 氢溴酸盐)
Effect of canthaxanthin on chemically induced mammary carcinogenesis PMID 1902560
Trihydroxycholestanoic acid
MCE
Olive GB 3772
Phentolamine for vasodilator treatment of severe heart
PI3K
Dihydroanthracene (二氢蒽)
Atxn2 Mouse Pre
DNA single
Boc
D
TIAL1 Human Pre
Ube2k Rat Pre
RING1 Human Pre
THUMPD1 Human Pre
PPY
H
Ube2k Mouse Pre
Propofol Protects Against Hepatic Ischemia Reperfusion Injury via Inhibiting Bnip3
MCE
Atg12 Rat Pre
DYRK1B Human Pre
Lmo4 Mouse Pre
PCSK1N Human Pre
PHLDA1 Human Pre
STK36 Human Pre
TSPAN5 Human Pre
PLEKHF1 Human Pre
6
MCE
The effect of serine phosphorylated claudin
RPL18A Human Pre
Inhibitory Activity of Honeysuckle Extracts against Influenza A Virus In Vitro and In Vivo PMID 33044658
Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery PMID 26462166
MCE
MCE
FAM162A Human Pre
导入 11（IPO11）基因
Fam162a Mouse Pre
Fmoc
Lysophospholipase, Vibrio sp.
豆腐柴提取物 (Premna microphylla Turcz.)
N
MCE
PS
Targeting Anti
PKA/PRKACA 蛋白, Canine (His)
MN58b
Photodynamic gel
MCE
Rpe65
MCE
DDPO
A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases PMID 9501205
alpha4beta2 nicotinic receptors with high and low acetylcholine sensitivity pharmacology, stoichiometry, and sensitivity to long
JS004
MCE
Alphitolic acid 19533
p
Type conversion of secretomes in a 3D TAM2 and HCC cell co
Discovery of Isoplumbagin as a Novel NQO1 Substrate and Anti
selective anticancer activity
非洲花椒提取物 (Zanthoxylum gilletii (De Wild.) P.G.Waterman)
Mometasone/Indacaterol/Glycopyrronium (MF/IND/GLY) and MF/IND at Different MF Strengths versus Fluticasone Propionate/Salmeterol Xinafoate (FLU/SAL) and FLU/SAL+ Tiotropium in Patients with Asthma PMID 36714049
Autologous micrograft accelerates endogenous wound healing response through ERK
In vitro and in vivo antibacterial activities of E
MCE
Discovery of a polysubstituted phenyl containing novel N
Discovery of Potent and Selective Inhibitors of Cdc2
Dimethoxycurcumin
MTSES
N
Methylamino
5
Novel CRBN
Supinine 551
Establishment of an in vitro method of rabbit embryo toxicity with toxicokinetics study PMID 34322893
Postprandial inhibition of gastric ghrelin secretion by long
Perindopril impurity 1
Cytotoxic 3,5
Y
MCE
MCE
ECSIT 蛋白, Human (His)
ZL
MCE
J
MCE
MCE
Rat IgG1 lambda, Isotype Control
Intestinal adipocytes transdifferentiate into myofibroblast
1
Calcitriol
C1
TSEN2 Human Pre
Primary structure of four allatostatins neuropeptide inhibitors of juvenile hormone synthesis PMID 2762309
Arid1a Rat Pre
ASAP2 Human Pre
Pik3r1 Rat Pre
BCL9L Human Pre
Dnaja1 Rat Pre
Ketoamine oxidase
Syngap1 Mouse Pre
AVE 0991 sodium salt
PIK3R1 Human Pre
PSME4 Human Pre
DPY19L2 Human Pre
IFT57 Human Pre
[The isolation and structural determination of naringenin and choerospondin from the bark of Choerospondias axillaris] PMID 6880758
N
鸡屎藤提取物 (Paederia foetida L.)
Artemin 蛋白, Human
Rpl18 Mouse Pre
Tazarotenic acid
3
CDC37L1 Human Pre
elevate ROS
6
MCE
6
MCE
YbdO Promotes the Pathogenicity of Escherichia coli K1 by Regulating Capsule Synthesis PMID 35628353
Kuwanon Y
N
ADNP
Fmoc
2′,3′,5′
L
Autophagy
Replication of CMV in the gut of HIV
Central opioid
Squalamine blocks tumor
Pharmacological characterizations of the 'legal high' fluorolintane and isomers PMID 31152702
MCE
6
ER
CSK peptide
The aggressive colorectal cancer subtype marker HTR2B has a dual role depending on the tumor microenvironment PMID 41034989
BD750 892686
MCE
ZX079
dual
CN427
JWU
APX004
OP
Ifi44
Esculeogenin A (番茄皂苷元)
Tz
AP23846
Spint2
CD247 分子（CD247）基因
Glutamate dehydrogenase (NAD(P)) 9029
含富含亮氨酸重复序列的免疫球蛋白超家族（ISLR）基因
Brutieridin
Hoechst 33342 trihydrochloride 875756
Lenalidomide
Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth PMID 32828423
MCE
DCAF11 ligand 2
IQ
改良番红 O
Atxn2 Rat Pre
Sulfo
PCGF1 Human Pre
Col1a2 Rat Pre
PLAAT4 Human Pre
BSDC1 Human Pre
PTBP1 Reduces KLF9 mRNA Stability and Upregulates FUBP1 to Promote Colorectal Cancer Stemness and Cisplatin Resistance PMID 40965935
(R)
VARS1 Human Pre
PLEKHB2 Human Pre
Gng3 Rat Pre
MCE
Ufsp2 Rat Pre
PRSS8 Human Pre
DNAJA1 Human Pre
CBX3 Human Pre
MCE
Glycyl
MCE
IDO/IDO/TDO_Inhibitor
Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury PMID 37419902
COAST An Open
Me
f
MCE
Bestatin
Proteinase A, baker's yeast (S. cerevisiae)
MCE
Neuropeptide W
MCE
Orthonitrophenyl
N
Carbohydrate
Bocaminooxyacetamide
Amino
N1,N4
Z
MCE
HGF 蛋白, Human (HEK293)
MCE
MCE
Overcoming EZH2 Inhibitor Resistance by Taxane in PTEN
Characterization of Sp
NDN Human Pre
MCE
ERK
N
Azido
MCE
Sulfo
Dexmecamylamine 107538
Targeting PI4KA sensitizes refractory leukemia to chemotherapy by modulating the ERK/AMPK/OXPHOS axis PMID 36276647
Design, synthesis, and biological evaluation of novel transrepression
MCE
MCE
DPYS 蛋白, Human (sf9)
BP Fluor 405 cadaverine
BCR ABL1 expression in chronic myeloid leukemia cells in low oxygen is regulated by glutamine via CD36
MCE
Safety and efficacy of MIM
CDH17
(S,R,S)
SOST 蛋白, Human (HEK293, His)
Rat brain guanosine binding site. Biological studies and pseudo
MCE
G
Iodine nanoparticles enhance radiotherapy of intracerebral human glioma in mice and increase efficacy of chemotherapy PMID 30872755
MCE
Eperisone
6
(S,R,S)
(S)
Targeting the chromatin binding of exportin
Selenium nanoparticles alleviate deoxynivalenol
Mechanosensitive ion channel Piezo1 mediates mechanical ventilation
Synthesis of 3
Defining gastric cancer ecology the crucial roles of TREM2+ macrophages and fibroblasts in tumor microenvironments PMID 40155473
Acemetacin 53164
Sulfonylamide Compounds as CDK2 Inhibitors for Treating Cancer PMID 34676031
Evofolin B 1961305
Calr
Inhalation of 2, 4
MCE
CPO_Aβ17
CWI1
Cucurbitacin E and I target the JAK/STAT pathway and induce apoptosis in Sézary cells PMID 33102814
Dual
N
6
FGL1 in plasma extracellular vesicles is correlated with clinical stage of lung adenocarcinoma and anti
Dabcyl
Integrin expression and integrin
Epirubicin HCl toxicity in human
N
EEF1B2 蛋白, Human (His)
SULT2B1 a novel therapeutic target in colorectal cancer via modulation of AKT/PKM2
In vitro characterisation of the novel positive allosteric modulators of the mGlu₅ receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat PMID 22884720
MCE
num
Different interaction profiles of direct
4,7,10,13,16
MCE
Benzil (Standard) 134
Carboxypeptidase B, Porcine pancreas (EC 3.4.2.2)
C24 Ceramide Lipid Nanoparticles for Skin Wound Healing PMID 40006608
The parathyroid calcium receptor a novel therapeutic target for treating hyperparathyroidism PMID 8792389
Dual scalable osteogenic microtissue engineering via GelMA microsphere
Biopeptides with antioxidant and anti
p
Sparc Rat Pre
p
FOXN2 Human Pre
6
SPART Human Pre
Dntt Rat Pre
Telo2 Rat Pre
Aminopeptidase I, Streptomyces griseus
TTPA Human Pre
Tie1 Mouse Pre
Glycyl
SuO
Sulfo Cy7 bis
Pseudolaric Acid B Alleviates Non
Z
α
BIN1 蛋白, Human (His)
MCE
Podxl2 Rat Pre
MSH5 Human Pre
MCE
Serpine2 Mouse Pre
Protein Kinase C (19
Ts
3
PRPF38B Human Pre
MCE
(
Pimitespib 1260533
5
Mucin
MCE
Cyanine 5 NHS ester tetrafluoroborate
L
MCE
Discovery of DC20 as a potential non
Fluo
In vitro inhibition of aromatase by the enantiomers of aminoglutethimide and analogs PMID 7857773
Studies on monoterpene glucosides. VII. Iridoid glucosides of Paederia scandens PMID 5347596
ATEE
Impact of drugs and environmental contaminants on amine production by gut bacteria PMID 40588570
SLFN5
Substrate specificity and stereoselectivity of rat brain microsomal anandamide amidohydrolase PMID 10072686
(Rac)
Aida Mouse Pre
pH
Synthesis and biological activity of Delta
Cell membrane chromatography relative competitive method for the accurate determination of relative KD values of drug
2
凝血因子 IIa
5
Etoposide impurity 1 (Standard)
Manipulation of alternative splicing by a newly developed inhibitor of Clks PMID 15010457
Liposome
c
Suppression of the LKB1
AGR 945245
Emodin protects against apoptosis and inflammation by regulating reactive oxygen species
Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis PMID 31467036
PEG3 67439
Exploring the NCS
Expression signature based on TP53 target genes doesn't predict response to TP53
Acicarpha
GCRV
NE 52
S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c
Edoxaban impurity 8 41374
NCAPG2 contributes to progression of malignant melanoma through regulating proliferation and metastasis PMID 36265182
L
Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway PMID 31485609
Fmoc
3
Cholic acid impurity 1
JS 004
6
PCSK1 蛋白, Human (HEK293, His)
Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta
Copper
A new indolocarbazole antibiotic, RK
MTH1 degrader
A phase I pharmacokinetic and pharmacodynamic study of CHR
Fuscin, an inhibitor of mitochondrial SH
MCE
Bacterium
Biology of IL
Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms PMID 20154467
Metal
MCE
Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress
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