最近收录_第744页_生物活性分子
生物活性分子最近更新
MCE
3,4,3'
Kallikrein
21
Sacubitrilat impurity 32
Fulvestrant
MCE
AhR
Design, diversity
Anti
Effect of DL
Flip and flop a cell
(E/Z)
Chlorthalidone impurity ammonium
Cd3g Mouse Pre
核糖核苷酸还原酶调节亚基 M2（RRM2）基因
Triclosan
泛素结合酶 E2 V2（UBE2V2）基因
乙酰胆碱酯酶（ACHE）基因
mmu
Melatonin alleviates oxidative stress and inflammation of Leydig cells of Min pig through SIRT1 pathway PMID 39613495
GSK702
D
Technical Support
Edoxaban impurity 63
Afatinib impurity 31
Linagliptin impurity 1
Edaravone impurity 2 (Standard)
Cabazitaxel prodrug nanoassemblies with branched chain modifications Narrowing the gap between efficacy and safety PMID 37451544
N3
Others 抑制剂
Metyrapone Tartrate 908
MCE
整合复合物亚基 6（INTS6）基因
KKL
Nepinalone hydrochloride 22443
Y
Carglumic acid promotes apoptosis and suppresses cancer cell proliferation in vitro and in vivo PMID 26885446
(R)
Antipruritic effect of ursolic acid through MRGPRX2/MrgprB2
MCE
A
(E)
O
Ametryn 834
Structural modifications on indole and pyrimidine rings of osimertinib lead to high selectivity towards L858R/T790M double mutant enzyme and potent antitumor activity PMID 33667898
视黄酸受体反应器 1（RARRES1）基因
Timm9
mmu
谷氨酸代谢型受体 1（GRM1）基因
Oxindole
程序性细胞死亡 4（PDCD4）基因
HACE1 Human Pre
BRITE
Trim24 Rat Pre
HIV
PROTAC BRD9 Degrader
Disperse blue 359
hsa
Ergolide 54999
2
MME 蛋白, Human (HEK293, Fc)
MCE
Development of a tetrahydroindazolone
Daclatasvir Impurity B
Calcitonin/CALCA 蛋白, Human (HEK293, His)
EpCAM/TROP1 蛋白, Rat (HEK293, Fc)
Vitamin C alleviates PM2.5
Nicodil impurity 1
Reg3a
Technical Support
agonist
Boc
Ibrutinib impurity 23
BRCA1 DNA 修复相关（BRCA1）基因
α2δ ligand 1
The heat shock protein 90 inhibitor 17
ATP6AP2 蛋白, Human (His
MCE
β
MCE
(S,R,S)
Triptoditerpenic acid B
Vdac2
Ticagrelor impurity 22 (Standard)
TOP1/TDP1
Aspulvinone H
N2
Trypsin promotes C6 glioma cell proliferation in serum
外泌体组分 7（EXOSC7）基因
Europetin (7
EBOV
hTopo
β
Herbaridine B
ROS
Vadadustat (Standard)
Mcl1
Ditophal (Etisul)
Formononetin ameliorates polycystic ovary syndrome through suppressing NLRP3 inflammasome PMID 39871124
FR
Pericyte loss via glutaredoxin2 downregulation aggravates diabetes
PCN
Micrococcin P1 (微球菌素 P1)
MCE
2
C18 1 Cyclic LPA
PICK1 PDZ
ULK1
2
Exatecan
5
Thalidomide
Trioxacarcin B (TXN
Meglitinide
FCER1A Human Pre
Disperse yellow 9 (Standard)
ASCC1 Human Pre
MIL
Antibacterial agent 18
Kallikrein
Desamino lenalidomide
TCF25 Human Pre
Zamifenacin (UK
Teprenone Impurity 5
5
TsaE 蛋白, E.coli
Design, Synthesis, and Biochemical Evaluation of Alpha
Quinovic acid 465
Zamifenacin fumarate (UK
Valenklin impurity 1
MCE
3'
Protocol for measuring labile cytosolic Zn2+ using an in situ calibration of a genetically encoded FRET sensor PMID 38870018
Antiviral agent 80
Nefazodone impurity 3
Green DND
ZCCHC7 Human Pre
Desamino lenalidomide
PTEN 蛋白, Human (GST)
Sutherlandin trans
222894
4
决明提取物 (Senna tora (L.) Roxb.)
PROTAC hCAII degrader
Rationally designed Pyrazolo[1,5
PLLA4000
Laevigatin A
Thiol
Disperse Blue 85
Otaplimastat hydrochloride (SP
7
2
Benzene
钙粘蛋白 15（CDH15）基因
KT53
Domperidone inhibits cell proliferation via targeting MEK and CDK4 in esophageal squamous cell carcinoma PMID 38528618
Angiotensin Converting Enzyme, Bovine
MCE
NCKIPSD 蛋白, Human (His)
ABT
Fmoc
NHNB
5
Synthesis and structural characterization of copper
Bis
Tubulin polymerization
MCE
Pooled endogenous protein tagging and recruitment for systematic profiling of protein function PMID 39255790
LY3214996 relieves acquired resistance to sorafenib in hepatocellular carcinoma cells PMID 33628103
hsa
NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin
Methyltetrazine
MCE
Fosaprepitant Dimeglumine Alleviates Dengue Virus Infection and Virus
N,N
Deoxycholic acid 3,12
Evaluation of carnitine, acetylcarnitine and isovalerylcarnitine on immune function and apoptosis PMID 16033249
Thalidomide
PROM1 Human Pre
Cincholic acid 3
2,5
3',5
RAR Inhibitors Display Photo
hsa
Selective Small
Assessment toxic effects of exposure to 3
Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors PMID 27750146
Induction of unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats exposed in vivo to the benzidine
(S)
2'
CRM197
O
Pteleine 2221
EG01449 Free acid
hsa
Analgesic and anti
(9S,13R)
MCE
Stearic acid
Ethacridine 442
Sdha Rat Pre
Kallikrein
Methyl arachidate 1120
RIPK1
N
Anti
MCE
TIM
Anti
Probing the signaling requirements for naive human pluripotency by high
Anti
BW 245C 72814
hsa
3
Proteolysis
4
Desamino lenalidomide
A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons PMID 24719092
E3 Ligase Ligand
Antileishmanial agent
Atrial natriuretic factor
A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments PMID 38810335
Part
Lazertinib mesylate hydrate (YH25448 mesylate hydrate)
KIF18A Is a Novel Target of JNK1/c
Disperse brown 4
Nanoparticle Size Influences the Self
Hispidone (鬃毛酮)
Fendleryl B
Acrofolione A
α
PanK1抑制剂、激活剂、调节剂、基因
R24
A new compound from Forsythia suspensa (Thunb.) Vahl with antiviral effect on RSV PMID 15277088
11α,12β
Mieshuan
Obefazimod (Standard)
3,3
Fissitungfine B
Acetylregaloside C (乙酰化王百合苷Ｃ)
diSPhMC
Withaperuvin C 81644
Ritlecitinib (Standard)
Boc
Loddigesiinol A
Guaiacol rutinoside (愈创木酚芸香苷)
Pyrroside A
SIGLEC8 Human Pre
Desamino lenalidomide
Ceftriaxone improves hepatorenal damages in mice subjected to D
SARS
(±)
Highly purified Type II collagen, from porcine articular cartilage (Porcine Type II collagen, immunization grade)
RO5166017
Cyclobutanedichalcone
MIL
3
H
NH2
Hericium Erinaceus Extract
FASN
Desiodomethyl 4
Urea, N
Enpp1 Mouse Pre
PROTAC DAPK1 Degrader
4A
(Rac)
Disperse orange 25
Fbxl3 Mouse Pre
Biotin
4
CYP11A1
Tpx2 Mouse Pre
STEAP1 蛋白, Rat (Cell
2
Topoisomerase IV, Streptococcus pneumoniae
8
WS
RbAp48
Neuroprotective agent 16
Hydrouracil
Fucosterol 17605
Dipentamethylenethiuram Tetrasulfide
Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells PMID 36898380
Carindacillin sodium (Carbenicillin indanyl sodium)
SNAP25 蛋白, Human (His)
Thalidomide
DBCO
22
hsa
CXCL5 signaling is a shared pathway of neuroinflammation and blood
SARS
HB
MRT68921 dihydrochloride (Standard)
Peptide
The Combination of Indole
2
A novel STAT3 inhibitor negatively modulates platelet activation and aggregation PMID 28260800
Anti
5(6)
Desamino lenalidomide
FSVVPSPK
hsa
2',4'
Antidepressant
Swine RNF5 positively regulates the antiviral activity of IFITM1 by mediating the degradation of ABHD16A PMID 39601593
Biotin
Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer PMID 38513095
MCE
Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression PMID 13716610
MCE
CRBN ligand
Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle PMID 34433903
MCE
hsa
hsa
p67phox 蛋白, Human (sf9)
4
tRNA methyltransferase DNMT2 promotes hepatocellular carcinoma progression and enhances Bortezomib resistance through inhibiting TNFSF10 PMID 39617358
Advances and Challenges of Liposome Assisted Drug Delivery PMID 26648870
hsa
MCE
4
(+)
Atractylenolide II induces G1 cell
Discovery, synthesis and mechanism study of 2,3,5
MCE
CRBN ligand
Monoamine Oxidase B inhibitor 6 101091
Computational Design of Lysine Targeting Covalent Binders Using Rosetta PMID 40440538
Exploration of hydrazine
MCE
HA
Anti
hsa
MCE
Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase PMID 12510831
Effect of the sphingosine kinase 1 selective inhibitor, PF
Hordenine hydrochloride 6027
Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose PMID 33313952
CD40 蛋白, Human (HEK293, Fc)
The anticoagulant effect of hexolame, N
Cystathionine β
Anti
Graveoline 485
(+)
MCE
LIGHT deficiency aggravates cisplatin
Sotrastaurin, a protein kinase C inhibitor, ameliorates ischemia and reperfusion injury in rat orthotopic liver transplantation PMID 21883905
7,3',4'
Memantine Derivatives as Multitarget Agents in Alzheimer's Disease PMID 32887400
1
SLLK, Control Peptide for TSP1 Inhibitor(TFA)
Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti
1
Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody
IMMP2L Human Pre
Desamino lenalidomide
PAGE2B Human Pre
RPL11 Human Pre
MCE
FXN Human Pre
Thalidomide
DNA
GPX4
PKMYT1
Lefucoxib
Angeloylgomisin O
KIDINS220 Human Pre
Xanthine dehydrogenase, Microorganism
5
Clausine K
Isovanillin
Investigation of the mechanism of baicalein in the treatment of periodontitis based on network pharmacology, molecular docking and experimental validation PMID 39180042
Rubiyunnanins C
DL
Renin
Rociletinib (Standard)
Arginase, Rat
Cinmetacin
Sodium Channel inhibitor 2
Rat IgG1 lambda, Isotype Control
16 0 PE MCC (N
Pedatisectine E
Fes Rat Pre
Synthesis and biological evaluation of 2,3
具芒小檗提取物 (Berberis aristata DC.)
Dichamanetin
Aard Rat Pre
SMER10
Crude Peanut extract (粗花生提取物)
Hecubine
3'
STEAP1B Human Pre
Ypenyl
Desamino lenalidomide
MCE
TEA 域转录因子 4（TEAD4）基因
α
MCE
Butyl isobutyl phthalate
Wushankaempferol
Topoisomerase IV, E. coli
Coumaperine
VEGFR
BAY
Padi3 Rat Pre
NOXA1 Human Pre
MCE
Topoisomerase I/IIα
TP53I3 Human Pre
Naringenin
VGLL4 Human Pre
Iodoacetamido
Perfluorobutanesulfonic acid
EA
Hydrouracil
Desamino lenalidomide
pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation PMID 36369429
Adenostemmoic acid G
Chondroitin sulfate (from fish) (Chondroitin polysulfate (from fish)，硫酸软骨素 (鱼))
6''
Gallic acid 3
EGLN1 蛋白, Human (His)
Farfugin A 36061
MCE
1
Alpha
8
MCE
EPT1 蛋白, Human (GST)
MCE
Laccase, White rot fungi
Cited2 Rat Pre
Triisopropylsilane, 98% (TIS, 98%)
Cipargamin enantiomer (NITD609 enantiomer)
Disperse Blue 106
Nesfatin
Collagen alpha
Dodecyl acetate 112
Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide PMID 31813613
Azoxymethane
hsa
Anti
ZFHX2 Human Pre
Hydroxy
Chronological Management of Adjuvant Effect for Optimized mRNA Vaccine Inspired by Natural Virus Infection PMID 39011561
PROTAC NAMPT Degrader
Heck
Inhibitory Effects of γ
Iluoridine impurity 9 (Standard)
flavanoids
Calmodulin and its roles in skeletal muscle function PMID 6307499
8
Iptacopan hydrochloride hydrate (LNP023 hydrochloride hydrate)
IL
Anti
5
1
Propargyl
Local Exosome Inhibition Potentiates Mild Photothermal Immunotherapy Against Breast Cancer PMID 39574346
hsa
L
hsa
Prilocaine impurity 1
4
N
(S)
Discovery of 4
Calcium sulfate dihydrate (99%) (Gypsum fibrosum (99%))
Iguratimod impurity 1
Calcipotriol Impurity C 113082
3
CRBN ligand
2′
Studies on the inhibition of histidine decarboxylase, aromatic
A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti
MCE
miR
Epithelial microRNA
Zebrafish prmt3 negatively regulates antiviral responses PMID 32643209
Dihydromyristicin 52811
The Association of Endothelin
hsa
Gallic and butyric acids modulated NLRP3 inflammasome markers in a co
Quinoxalinylethylpyridylthioureas (QXPTs) as potent non
Ganglion cell
Chicken leg bone as a source of chondroitin sulfate PMID 30599999
RDS
IgG3 Fc 蛋白, Mouse (230a.a, HEK293)
MCE
mmu
Glyuranolide
TCF23 Human Pre
Thalidomide
MCE
TARDBP Human Pre
Apigenin
Hydrouracil
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