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Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress
MCE
BAPTA
monohydrate
A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule PMID 20650892
Suppressive activity of epinastine hydrochloride on TARC production from human peripheral blood CD4+ T cells in
Amino
3,3
Hydrolyzed collagen improves bone status and prevents bone loss in ovariectomized C3H/HeN mice PMID 21927918
ALA protects against ERS
Dexamethasone impurity 2 360
Demethoxyhexahydrocurcumin
APS3
Determination of the rate of muscarinic M1 receptor plasma membrane delivery using a regulated secretion/aggregation system PMID 16213169
Cy3
Identification of a Polyketide Synthase Gene Responsible for Ascochitine Biosynthesis in Ascochyta fabae and Its Abrogation in Sister Taxa PMID 31554725
CEF4
MCE
Characterization of CDK(5) inhibitor, 20
Tamsulosin impurity 15
m
Identification and characterization of a potent and biologically
Leptomycin B inhibition of signal
AD013
The antibiotic furagin and its derivatives are isoform
Lys
von Hippel
Dihydrogeodin
SH
Design, modification and 3D QSAR studies of novel naphthalin
Methyl
Bin1
Stc1 Rat Pre
Gatm Mouse Pre
Amhr2 Mouse Pre
N
ACOX2 Human Pre
MCE
RPF2 Human Pre
Rpf2 Mouse Pre
Aspartate Aminotransferase, Human
Aluminum hydroxide adjuvants activate caspase
EMILIN3 Human Pre
Targeting MET Discovery of Small Molecule Inhibitors as Non
Fmoc
Uba6 Mouse Pre
Angiogenin 蛋白, Human (His)
Fbxo22 Rat Pre
Cbz
Anti
MCE
Methyl pentacosanoate
MCE
Inhibition of glycosphingolipid synthesis with eliglustat in combination with immune checkpoint inhibitors in advanced cancers preclinical evidence and phase I clinical trial PMID 39138212
Monophosphoryl lipid A 1246298
Selection, synthesis, and anti
Tenatumomab (ST2146，替妥莫单抗)
Discoidin domain receptor inhibitor DDR1
Glucocorticoids improve the balance of M1/M2 macrophage polarization in experimental autoimmune uveitis through the P38MAPK
Quercetin 3,4′
Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071 PMID 21930376
CD247
MCE
N
Discovery of Novel Thiophene
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia PMID 38753484
Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors PMID 19388647
5
MCE
Hypolipidemic, anti
Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI
L
Valencene 4630
Microbiome
G
6
Aucubin 479
Caenorhabditis elegans
8
Ribose
Mstn
AIBP protects drug
Ac
4
Discovery of novel sitolactone derivative leading to PANoptosis and differentiation of acute myeloid leukemia cells PMID 39983554
Coumarin 343 X NHS ester (Coumarin 343
Activation of autophagy mediated by PI3K/Akt/mTOR signalling cascade alleviates impaired adipose
Down
Azido
THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation PMID 17367527
CFT
phoBET1
Obinutuzumab
[Clinical evaluation of lenampicillin in the treatment of superficial suppurative skin and soft tissue infection. A double
FD1024 1422456
Arid1b
DBCO
8(S)
Amicoumacin C
MCE
Paprotrain (Standard)
BAS00093476
11
MGL
NSC 23925B
DMH2 (VU364849)
p38 MAPK
Antibacterial agent 152
Atxn2l Rat Pre
ATXN2 Human Pre
Steap2 Mouse Pre
allo
Protein O
Entadoside A
SPARC Human Pre
Pgm1 Mouse Pre
RB
RAB34，RAS 致癌基因家族成员（RAB34）基因
Bis
(R)
GOSR2 Human Pre
DNA
PLEKHN1 Human Pre
MCE
ARHGAP9 Human Pre
Pdcd4
CD3G
Formic acid ammonium (Standard) (Ammonium formate (Standard))
UFSP2 Human Pre
Sesquiterpenoids from Incarvillea arguta absolute configuration and biological evaluation PMID 22620677
RB
Tos
Cyanine5.5 NHS ester chloride TEA
3
Baricitinib 4
SP
Me
RFQF4
(all
MCE
IL
MCE
Bis
Pdcd4
Gageotetrin A 1536405
RO5527239
Afatinib impurity 7 (Boc
5'
Bamipine
Insulin detemir enhances proglucagon gene expression in the intestinal L cells via stimulating β
MCE
CD72 分子（CD72）基因
KRpTIRR
MCE
N
N
Saa4
利钠肽 A（NPPA）基因
Elubiol (Dichlorophenyl imidazoldioxolan)
A
Mycoplanecin A
MCE
Both Cyclophilin Inhibitors and Direct
The potent protein kinase C
CBP
MCE
NEDD4L 蛋白, Human
MCE
MCE
GPT2
Glibenclamide 10238
Homoyessotoxin alleviates inflammatory responses by regulating the TLR4/MyD88/NFκB and Nrf2/HO
N
Effect of long
M2 macrophages
Roxindole hydrochloride 108050
Methyl 4
Deletion of prolyl hydroxylase domain
WW437
COL1A1 蛋白, Human (HEK293, His)
杀伤细胞免疫球蛋白样受体，两个 Ig 结构域和短胞质尾 1（KIR2DS1）基因
Egg yolk oils exert anti
Dipivefrin hydrochloride 64019
4
Fmoc
Embryo injected with Ochratoxin A induced jejunum injury in ducklings by activating the TLR4 signaling pathway Involvement of intestinal microbiota PMID 38945100
N6
α
Mislocalize
4
Design, synthesis, anticancer evaluation, and In silico studies of 2
ZMYM3 Human Pre
Nα
A broad
GNF
Toliprolol (托利洛尔)
o
LDDN
Bipolamine G
LY3325656
AU
Uncoupling the CRMP2
Sulfo
K
Isovitexin accelerates diabetic wound repair via coordinated angiogenesis and collagen remodeling Mechanistic insights from cellular and streptozotocin
Exploring the effect and mechanism of action of Jinlida granules (JLD) in the treatment of diabetes
Human leukocyte esterase (unsonicated)
β2
Traxoprodil decreases pentylenetetrazol
MCE
Col2a1
MCE
Sulfo
Oral administration of GZ
Map3k14
Brevinin
2
AD 12115
N
4’
3'
ATXN2L Human Pre
Abacavir 5′
HITCI
Gatm Rat Pre
Internal Transcribed Spacers (ITS) rRNA blocker
Glucose dehydrogenase, Pseudomonas sp.
ML229
Kng1 Rat Pre
PNPO Human Pre
CRLF1 Human Pre
Colipase, Porcine
MMRN2 Human Pre
BCL9 Human Pre
MCE
Sulfo
Spink2 Mouse Pre
L
The novel toluidine sulphonamide EL102 shows pre
Floridolide B
11
MCE
Seldomycin factor 2 54333
3,4
LDLRAD4 Human Pre
Cyanine5.5 NHS ester chloride
Afatinib impurity 7 (Standard)
Azido
3
MCE
m
Suvorexant impurity 1
Cdh1
Synthesis of 4
Picein 530
Time
MtTMPK
8
Evolatine 524
Fmoc
dIMP
Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance PMID 26743932
ML335
Fatty Acid Synthase (FASN)
p
Clinical MDR1 inhibitors enhance Smac
Semaphorin
(2S)
TLR7 antagonist
RBM24 controls cardiac QT interval through CaMKIIδ splicing PMID 36454480
N
The effect and mechanism of areca nut in ovarian cancer were investigated based on network pharmacology, molecular docking, and in vitro experiments PMID 40398091
MEF2B Human Pre
N
Pantoprazole impurity 1
β
MCE
Scaffold hopping of celastrol provides derivatives containing pepper ring, pyrazine and oxazole substructures as potent autophagy inducers against breast cancer cell line MCF
Txndc12 Rat Pre
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis
PL37
Inhibitory activity of luteinizing hormone
Low shear stress induces ERK nuclear localization and YAP activation to control the proliferation of breast cancer cells PMID 30685085
CRBN ligand
A Comprehensive Review on the Phytochemical Constituents and Pharmacological Activities of Pogostemon cablin Benth. An Aromatic Medicinal Plant of Industrial Importance PMID 25985355
Bevacizumab vedotin
Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype
D
MSC transplantation ameliorates depression in lupus by suppressing Th1 cell
Vardenafil dihydrochloride PMID 24794912
Toxic Shock Syndrome Toxin
PD 128907 hydrochloride (PD 128907（盐酸盐）)
In silico discovery of small
Exendin‑4 promotes osteogenic differentiation of adipose‑derived stem cells and facilitates bone repair PMID 31661134
TFEB activator 1 39777
Isomaltulose monohydrate 58024
JS
Transferrin 蛋白, Rat (HEK293, His)
Deletion of Tgm2 suppresses BMP
Anti
Metabolism and time
ZZL
AMHR2/MISRII 蛋白, Human (HEK293)
Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2 PMID 39275006
IMP4
SPINK2
ML
RIPK
VEGF2
Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies PMID 27007053
Gasdermin D
TROP2
D
BG
4,5'
Benzo[c]phenanthrene
Crlf1 Rat Pre
Cd81 Rat Pre
Atg4B activator
Ptk2b Mouse Pre
Excess phosphate promotes SARS‑CoV‑2 N protein‑induced NLRP3 inflammasome activation via the SCAP‑SREBP2 signaling pathway PMID 38275129
SESTD1 Human Pre
cis
Desethoxy Quetiapine (Quetiapine hydroxy impurity)
MCE
MRPS23 Human Pre
GLRX5 Human Pre
Regulation of insulin resistance by targeting the insulin
Amino
H
ADAM33 Human Pre
Solanesol Ameliorates Anxiety
液相色谱
Corey lactone benzoate impurity 1
Photo
MCE
CFT 1297
Fast garnet GBC sulfate salt, 90% (Azoic diazo No. 4, 90%)
MCE
(S)
L
MCE
Vacquinol‑1 induces apoptosis in hepatocellular carcinoma cell PMID 29749500
MCE
Neonatal administration of thimerosal causes persistent changes in mu opioid receptors in the rat brain PMID 20803069
MCE
CircSETD3 interrupts the bidirectional positive feedback of ErbB3 and Akt by sponging miR
4
2
Baroxavir impurity 17
Pyoluteorin induces cell cycle arrest and apoptosis in human triple
DUT Human Pre
Exploring novel microbial metabolites and drugs for inhibiting Clostridioides difficile PMID 38940508
N
Dual PI3K/mTOR Inhibitor BEZ235 combined with BMS
2,5
L
Hirudinoidine A
MCE
Lack of effect of a 5
Polygalasaponin F 882664
β
Autotaxin
2
CD73
Effects of Rupatadine on Platelet
GLP
nephroprotective
Abcd3 Rat Pre
Rutoside
Guest
Rutin
Quercetin 3
mTORC1 induces plasma membrane depolarization and promotes preosteoblast senescence by regulating the sodium channel Scn1a PMID 35256591
pyrrolidinone
G
Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo PMID 9113359
Ceftobiprole
Ro 63
Activation of the integrins alpha 5beta 1 and alpha v beta 3 and focal adhesion kinase (FAK) during arteriogenesis PMID 18998200
BAL9141
Studies on inhibitors of skin tumor promotion, XII. Rotenoids from Amorpha fruticosa PMID 8350086
Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation PMID 24512768
ERR alpha 抗体 (YA2283)（ERR alpha Antibody (YA2283)）
staphylococci
G
BAL 9141
MRSA
Claudin family of proteins and cancer an overview PMID 20671913
pathogens
Indole
MCE
VRSA
In vitro activity of ceftobiprole on 440 Staphylococcus aureus strains isolated from bronchopulmonary infections PMID 27856079
Influenza antiviral activity of F
BAL
KB
Famitinib 1044040
Pro
Ceftobiprole, a Broad
A20 alleviated caspase
penicillin
BAL 9141
gram
MitoAMPK inhibits the Warburg effect by MZF1
万古霉素 (Standard)
Efficacy of BAL5788, a prodrug of cephalosporin BAL9141, in a mouse model of acute pneumococcal pneumonia PMID 15047508
Combined transcriptomics and network pharmacology to elucidate the mechanisms of rutin in treating ischemic stroke rat PMID 40975038
Serine hydroxymethyltransferase revisited PMID 16125438
FITC
Activities of ceftobiprole and other cephalosporins against extracellular and intracellular (THP
CD38 蛋白, Rabbit (HEK293, His)
Estrogen Related Receptor gamma 抗体 (YA2009)（Estrogen Related Receptor gamma Antibody (YA2009)）
CD38 蛋白, Cynomolgus (HEK293, His)
Atrial natriuretic peptide a new factor in hormonal control of blood pressure and electrolyte homeostasis PMID 2939792
紫皮甙水合物
头孢托罗
In Vitro and In Vivo Evaluation of a Small
头孢吡普
维生素 P 水合物
ANAPC10 Human Pre
Adventitial fibroblast
白细胞酪氨酸激酶
芦丁水合物
芸香苷水合物
Technical Support
CB<sub>1</sub>R
白细胞相关免疫球蛋白样受体 1
Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia PMID 39725939
rac
MCE
mmu
The mechanism underlying redundant functions of the YTHDF proteins PMID 36694229
GFRA3/GDNFR
CRBN ligand
Strategies toward the design of novel and selective protein tyrosine kinase inhibitors PMID 10454197
CRBN ligand
N
MCE
4
14
D
Teriparatide
Razuprotafib sodium (AKB
Derritol (鱼藤酚)
Proanthocyanidins in health care current and new trends PMID 15134524
COL1A2 Human Pre
Technical Support
ARMCX1 Human Pre
2
Mthfd1l Rat Pre
Harmol promotes α
Pantothenate kinase
Glyceollin III (大豆素 III)
JAK2
Thalidomide
UBA6 Human Pre
YIPF3 Human Pre
Bis(vinylsulfonyl)piperazine
Adipocyte CLDN5 promotes thermogenesis and energy expenditure through regulation of IL10 expression PMID 40610440
Mechanism of intestinal paracellular absorption of shrimp peptide QMDDQ regulated by myosin light chain kinase PMID 40590404
Trehalose
Adam33 Mouse Pre
SUPT4H1 Human Pre
CH3OCO
Tetranitroblue tetrazolium chloride
α
N
MCE
MCE
Cefaclor in vitro spectrum of activity and beta
TCO
Azido
(S,R,S)
MCE
Benzyl N1
LRP1 抗体 (YA306)（LRP1 Antibody (YA306)）
4
N
(S,R,S)
Tomoxiprole selectively inhibits cyclooxygenase
Desoxyanisoin 120
Baicalin Coadministration with Lithium Chloride Enhanced Neurogenesis via GSK3β Pathway in Corticosterone Induced PC
Repression of phosphoenolpyruvate carboxykinase gene activity by insulin is blocked by 3
Symmetrical alpha
Denatonium benzoate
红丝姜花提取物 (Hedychium gardnerianum Sheppard ex Ker Gawl.)
Monoamine Oxidase B inhibitor 2 2807477
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models PMID 16397258
Synthesis, biological evaluation, in silico modeling and crystallization of novel small monocationic molecules with potent antiproliferative activity by dual mechanism PMID 32977218
Eya2
Cdh1
Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages PMID 14631377
Brevinin
Clobutinol 14860
Z
19
Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats PMID 20303838
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