最近收录_第783页_生物活性分子
生物活性分子最近更新
Characterization of two structurally novel HIV
3α
Long wavelength
Canagliflozin 842133
Ereg
H3K9 post
Anti
Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells PMID 35139387
CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells PMID 39637858
4
The CRAC channel inhibitor BTP2 restricts Tulane virus and human norovirus replication independent of store
Tauroursodeoxycholic acid
Comparison of the antimuscarinic and antispasmodic actions of racemic oxybutynin and desethyloxybutynin and their enantiomers with those of racemic terodiline PMID 9825119
Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP PMID 29540530
(Rac)
MCE
Chemical Profiling of Chixiaodou Danggui San Using Liquid Chromatography
MCE
周膜蛋白（PPL）基因
Regulation of carbohydrate metabolism by glucose 1,6
ASNS Human Pre
BAY
Potential Use of Alginate
Catestatin alleviates PASMC phenotypic switching
Neddylation is essential for β
Geranyl monophosphate 1609182
4
IL
2
Identification of N
肌营养蛋白（UTRN）基因
Chemiluminescence of the Ce(IV)/CDP
Inhibition of myeloperoxidase oxidant production by N
帕金森病相关去糖酶（PARK7）基因
Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus PMID 21466220
Chemogenetic activation of the HPC
LDN
α
17β
The differential diagnosis of dicarboxylic aciduria PMID 6434845
AZD3409 345915
SARS
Evidence that tyrphostins AG10 and AG18 are mitochondrial uncouplers that alter phosphorylation
Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death PMID 36468682
Adgrb2
S
Salvianan A 2162956
Bnip3l Mouse Pre
Propionylglycine (Standard)
ER
(1R,4S)
IRFI
HNRNPU Human Pre
8
Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas PMID 36206767
Dominance of ErbB
Auriculasin
JAK1
The structure of phosphorylated GSK
VMA21 Human Pre
Targeting the glial
细胞分裂周期 20B（CDC20B）基因
hnRNP U 抗体 (YA980)（hnRNP U Antibody (YA980)）
Therapeutic targeting of BET bromodomain proteins in castration
Restoration of the GTPase activity and cellular interactions of Gαo mutants by Zn2+ in GNAO1 encephalopathy models PMID 36206333
Phytochemical studies of Rehmannia glutinosa rhizomes PMID 12967042
科研有礼 集卡同行
BS2G Crosslinker
UNC1215
Dimethylformamide
Ulixacaltamide
Art4
(R,S,R)
GSK
rel
tert
MCE
BMS
Methyl (9R,10S)
Janus 激酶
Empagliflozin impurity 15 (Standard)
N6 Medium (Agar
7,8
N
NVP
MCE
Gelsemine 509
N2
TsO
IL
(Rac)
5
LW6 934593
DCTPP1 regulates oxidative stress homeostasis via AUF1 in human villous trophoblasts PMID 40849295
Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences PMID 15479820
Exploiting membrane vesicles derived from avian pathogenic Escherichia coli as a cross
t
Ehhadh
5,7
PTD
Cadmium biphasically impacts the adaptive immune system via regulating mitochondrial activation of hematopoietic stem cells in mice PMID 39725238
Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD
Recombinant chitinase
SHC4 Human Pre
Nelfinavir, A lead HIV protease inhibitor, is a broad
GRL
Epiaschantin 41689
Inhibition of IRE1α
PD 72953
Qige Decoction attenuated non
Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2 PMID 19694723
Association of CYP1A1 and CYP1B1 inhibition in in vitro assays with drug
Cortisol sulfate sodium (Standard)
Activator Protein 1
Amquinate (胺喹甲酯)
MCE
E3 Ligase Ligand
ROCK
N
rel
NIPSNAP2 Human Pre
The kinetics of carboxypeptidase B activity. II. Kinetic parameters of the cobalt and cadmium enzymes PMID 13945772
Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability
MG
STYK1 promotes autophagy through enhancing the assembly of autophagy
Mog
KU
Encaleret sodium 787584
MCE
COX
ddCTP trilithium 93939
Acepromazine
N
Ceritinib (LDK378) inhibits laryngeal squamous cell carcinoma progression via regulating ROS
SPI1 Transcriptional Activates TXNRD1 to Protect Trophoblast Cell from Ferroptosis PMID 40826214
PARP14
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor
MCE
Etravirine 269055
tert
Elf1
Delmopinol hydrochloride
Vitexicarpin suppresses malignant progression of colorectal cancer through affecting c
Effects of Sanguis Draconis on Perforator Flap Survival in Rats PMID 27681718
Methyl 2
MCE
1,4
Tos
2
Toosendanin alleviates dextran sulfate sodium
(2S,3R)
3
Neuroprotective and Anti
Discovery of new cyclopropane sulfonamide derivatives as EGFR inhibitors to overcome C797S
Pipernonaline 88660
In vivo evidence for carrier
Exacerbated lung inflammation in offspring with high maternal antibody levels following secondary RSV exposure PMID 38745662
Emodin delays rheumatoid arthritis progression by inhibiting the ROS/TXNIP/NLRP3 signaling pathway PMID 40388860
Anti
Omapatrilat 167305
Anti
Systemic toxicity induced by topical application of perfluoroheptanoic acid (PFHpA), perfluorohexanoic acid (PFHxA), and perfluoropentanoic acid (PFPeA) in a murine model PMID 36435305
Ganoderic acid T
trans,trans
(
O
(S,R,S)
Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy
Long Noncoding RNA MALAT1 Contributes to Sorafenib Resistance by Targeting miR
Comparison of ximelagatran with warfarin for the prevention of venous thromboembolism after total knee replacement PMID 14585938
m
An antimesothelin
Synthesis and biological evaluation of nucleoside analogues having 6
IGF2BP1
Lidorestat 245116
ER degrader 4 2913192
Sophoridine Inhibits the Tumour Growth of Non
[Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro] PMID 24417087
Caspase
Gut bacteria
Sertaconazole induced toxicity in HeLa cells through mitotic arrest and inhibition of microtubule assembly PMID 33620548
Nes Rat Pre
Macrophage migration inhibitory factor as a prognostic biomarker in multiple myeloma clinical significance and in vitro effects PMID 40628663
(rel)
MCE
Sdc3 Rat Pre
Discovery of potent ureido tetrahydrocarbazole derivatives for cancer treatments through targeting tumor
25
5
Novel derivatives of anaplastic lymphoma kinase inhibitors Synthesis, radiolabeling, and preliminary biological studies of fluoroethyl analogues of crizotinib, alectinib, and ceritinib PMID 31425908
Anti
dCas9
Tarvicopan 2378381
Sulfite oxidase 抗体 (YA6789)（Sulfite oxidase Antibody (YA6789)）
GSK547 2226735
Stable Isotope
N
Prenylisoflavonoids from Erythrina senegalensis as novel HIV
IHR
Allosteric stabilization of 3H
天冬酰胺合成酶 (谷氨酰胺水解)（ASNS）基因
MCE
糖原合酶激酶 3 β（GSK3B）基因
SUOX Human Pre
RS1 Human Pre
2
Rosuvastatin impurity 50
HA/Hemagglutinin 蛋白, H1N1 (QEM24709, sf9, His)
[Action of pristinamycin on Chlamydia] PMID 6429616
CNX
Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses PMID 24337933
The synergistic effect of valsartan and LAF237 [(S)
Corilagin suppresses RANKL
YH25448, an Irreversible EGFR
1
MCE
Interleukin 20 discovery, receptor identification, and role in epidermal function PMID 11163236
LKPNM a prodrug
Identification of exosomal circRNA CD226 as a potent driver of nonsmall cell lung cancer through miR
Alisol A Alleviates Arterial Plaque by Activating AMPK/SIRT1 Signaling Pathway in apoE
MCE
Discovery and Development of Small
MCE
Discovery of TAK
Pax3 inhibits Neuro
Stearic acid
Induction of cellulase and hemicellulase activities of Thermoascus aurantiacus by xylan hydrolyzed products PMID 22806786
多巴胺受体 D1（Drd1）基因
(R,S)
tert
5,6
Pharmacological investigation of new niclosamide
Rtn4r
SH3PXD2A 蛋白, Human (Myc, His)
Aplysin
VER 82576
P
Bromoacetamido
Quantitative analysis of total reflection X
A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations PMID 32504577
Fosalvudine tidoxil 763903
MCE
MCE
Angiotensin II induces podocyte metabolic reprogramming from glycolysis to glycerol
MCE
MCE
VCAM1 binding peptide 1311293
Pep2
Geniposide suppressed OX
1
FAAH/MAGL
Pizuglanstat 1244967
HIV
MCE
Calcium phosphorylcholine
In vitro antimicrobial activity of wall teichoic acid biosynthesis inhibitors against Staphylococcus aureus isolates PMID 21098254
Curcumenol exerts anti
MID1IP1 蛋白, Human (His)
Discovery of S64315, a Potent and Selective Mcl
4
(3R,6S)
Ultrasound
T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1 PMID 8585721
3
TC
Core Modifications of GSK3335103 toward Orally Bioavailable αvβ6 Inhibitors with Improved Synthetic Tractability PMID 39417301
(R)
Dysregulation of Rho
Overexpression of BACH1 mediated by IGF2 facilitates hepatocellular carcinoma growth and metastasis via IGF1R and PTK2 PMID 35154476
Asperidines A
Cobicistat 1004316
MCE
MCE
Superagonism at the human somatostatin receptor subtype 4 PMID 15333679
Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation PMID 35570091
G 蛋白亚基γ2（GNG2）基因
pH regulators and their inhibitors in tumor microenvironment PMID 38308950
Nitrophenylpiperazine derivatives as novel tyrosinase inhibitors design, synthesis, and in silico evaluations PMID 38581040
The investigation of the interaction of warangalone with transferrin as a therapeutic biological macromolecule and the formation of a protein
Andrastins A
Inhibitors of platelet signal transduction as anti
102157402
Profiling of glucosinolates and flavonoids in Rorippa indica (Linn.) Hiern. (Cruciferae) by UHPLC
CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML PMID 35326705
CNTs
Potent peroxisome proliferator
Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation PMID 35172156
Synthesis, docking, MD simulation, ADMET, drug likeness, and DFT studies of novel furo[2,3
Arginase inhibition mediates cardioprotection during ischaemia
Sameridine
Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension PMID 15252126
The use of S
Effects of perillyl alcohol on melanoma in the TPras mouse model PMID 12050099
Activation of the sigma
A multimorphic variant in ThPOK causes an inborn error of immunity with T cell defects and fibrosis PMID 40392549
Capturing the Effects of Single Atom Substitutions on the Inhibition Efficiency of Glycogen Synthase Kinase
Formate reduces ischemic injury in female hearts lacking alcohol dehydrogenase 5 PMID 40766369
N 2
Food
Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes PMID 19746978
Organosulfur compounds alone or in combination with vitamin C protect towards N
Clemastine PMID 31644019
The Unfolded Protein Response and Cell Fate Control PMID 29107536
Paris saponin VII induces cell cycle arrest and apoptosis by regulating Akt/MAPK pathway and inhibition of P
Conessine as a novel inhibitor of multidrug efflux pump systems in Pseudomonas aeruginosa PMID 28806947
Decrease in expression or activity of cytosolic phospholipase A2alpha increases cyclooxygenase
Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats PMID 34024778
Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2
Bicuculline block of small
一般转录因子 IIA 亚基 1（GTF2A1）基因
Targeting USP21 to inhibit abdominal aortic aneurysm progression by suppressing the phenotypic transition of vascular smooth muscle cells PMID 40925375
Angiotensin II can trigger HSC
Effects of dual angiotensin
c
Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses PMID 12410540
The CRF1 receptor mediates the excitatory actions of corticotropin releasing factor (CRF) in the developing rat brain in vivo evidence using a novel, selective, non
Control of oxygen free radical formation from mitochondrial complex I roles for protein kinase A and pyruvate dehydrogenase kinase PMID 11864782
Eps8l1
Targeting HDAC/OAZ1 axis with a novel inhibitor effectively reverses cisplatin resistance in non
C4
Characterization of gonadotropin
CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress PMID 33108758
Design, synthesis, and evaluation of 9
In vitro and in vivo inhibitory effects of 6
Tissue
蛋白酶体 20S 亚基 β 8（PSMB8）基因
Eteplirsen in the treatment of Duchenne muscular dystrophy PMID 28280301
Effect of feeding solanidine, solasodine and tomatidine to non
(N)
1400W ameliorates acute hypobaric hypoxia/reoxygenation
Development of a chemical probe against NUDT15 PMID 32690945
Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus PMID 25182650
D
Structure
Adenine nucleotides as potent and selective GPR17 modulators PMID 41619441
Effects of deoxynucleosides on cultured human leukemia cell growth and deoxynucleotide pools PMID 6975653
Effects of dietary omega
Design, synthesis and bioevaluation of novel combretastatin A
Inhibition of protein synthesis in vitro and in vivo by nucleocidin, an antitrypanosomal antibiotic PMID 5933868
Synthesis and in vitro antitubercular activity of some 1
The absence of oestrogen receptor beta disturbs collagen I type deposition during Achilles tendon healing by regulating the IRF5
Distinct requirements for activation at CCK
Identification of multiple 5
Induction of differentiation and apoptosis in leukaemic cell lines by the novel benzamide family histone deacetylase 2 and 3 inhibitor MI
Targeted Degradation of BET Proteins in Triple
Inhibition of hKv2.1, a major human neuronal voltage
Effect of a heterotrimeric G protein alpha subunit on conidia germination, stress response, and roquefortine C production in Penicillium roqueforti PMID 19784932
Drug
D
Macrophage migration inhibitory factor in the PVN attenuates the central pressor and dipsogenic actions of angiotensin II PMID 16809436
Isolation, purification and characteristics of R
Lumbar instability remodels cartilage endplate to induce intervertebral disc degeneration by recruiting osteoclasts via Hippo
日本血吸虫感染 (Schistosoma Japonicum Infection)
Bis
Ga
Phosphocholine
A judgment on postmortem aging in longissimus dorsi based on a peptide substrate library PMID 17151460
Design and Structural Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High In Vivo Potency and Oral Bioavailability PMID 36961373
Sesamin Exerts Anti
KL044 1801856
Synthesis and biological evaluation of novel steroidal 5α,8α
Synthesis, biological evaluation, Structure
Notch ligand delta
Exogenous hepatocyte growth factor markedly stimulates liver regeneration following portal branch ligation in dogs PMID 8646797
1,3
DSPS
Tissue
rel
ECHS1, an interacting protein of LASP1, induces sphingolipid
Nuclear Factor
Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi PMID 22348826
Demyelination in the medial prefrontal cortex by withdrawal from chronic nicotine causes impaired cognitive memory PMID 38036034
Antimicrobial and antibiofilm activity of fungal metabolites on methicillin
Antibiofilm agent
Tuberculosis inhibitor 4
The novel isoxazoline ectoparasiticide lotilaner (Credelio™) a non
Homolog
MCE
Transformation of a Potent C9
MCE
Effect of WR
PGF2α analogue
Machine learning
Efficacy of lasalocid against murine Pneumocystis carinii pneumonitis PMID 8980779
MMS19 同系物，胞质铁硫组装成分（MMS19）基因
3’
Chlorophylls A Personal Snapshot PMID 35164358
Design, synthesis, and DNA
Discovery of Novel Small
扩展突触结合蛋白 2（ESYT2）基因
Discovery of Novel Substrate
2
The IOP
HPLC
Nox2 and Nox4 Participate in ROS
Hyperthermia induced by thyrotropin
3,5,7,3',4'
The utilisation of creatine and its analogues by cytosolic and mitochondrial creatine kinase PMID 8664304
Sufugolix 308831
Yunaconitine 70578
Mniopetal B 158760
Discovery of HW201877 A Highly Potent and Orally Bioavailable Inhibitor of 15
Antifungal activity of sakurasosaponin from the root extract of Jacquinia flammea PMID 21740284
Otilonium bromide ameliorates pulmonary fibrosis in mice through activating phosphatase PPM1A PMID 39160244
Effect on neutrophil migration and antimicrobial functions by the Bruton's tyrosine kinase inhibitors tolebrutinib, evobrutinib and fenebrutinib PMID 38976501
Potent CaV3.2 channel inhibitors exert analgesic effects in acute and chronic pain models PMID 35728351
Synthesis of Demissidine and Solanidine PMID 27232858
TSU
Corticotropin
Remzistotug 2920425
MK2
Development of novel seleno
NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes PMID 38169395
The effects of phenobarbital, atropine, L
Inosinic acid
无名指蛋白 112（RNF112）基因
Sulfonoquinovosyl diacylglyceride selectively targets acute lymphoblastic leukemia cells and exerts potent anti
Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self
Design of Promising Thiazoloindazole
(S,R,S)
Application of linear gradient elution in countercurrent chromatography for the separation of triterpenoid saponins from the roots of Pulsatilla koreana Nakai PMID 28544207
Cap
Moth Cytochrome C (MCC) (88
Specific and time
BQ
Expanding the druggable zinc
Cooperative contributions of interferon regulatory factor 1 (IRF1) and IRF8 to interferon
HIV
Tnfrsf11b
The in vitro activity and beta
Oxazosulfyl, a Novel Sulfyl Insecticide, Binds to and Stabilizes the Voltage
Pomalidomide
Herpes Simplex Virus 1
α
Repurposing alcohol
Z
Expression of adhesion molecules in the rectum
TNFRSF17
Discovery of N1
A single Na+
Truncated (N)
Sertraline ameliorates inflammation in CUMS mice and inhibits TNF
Eudesmin impairs adipogenic differentiation via inhibition of S6K1 signaling pathway PMID 30316515
N
In vitro
Discovery of natural catechol derivatives as covalent SARS
Discovery of CZL
Discovery of Novel Oleamide Analogues as Brain
Design, synthesis and antimycobacterial activity of benzoxazinone derivatives and open
Metabolism of a potent neuroprotective hydrazide PMID 23582448
GNF
Inhibition of EZH2 by chidamide exerts antileukemia activity and increases chemosensitivity through Smo/Gli
Protective effect of acetyl
TAK
Ethylene carbonate
Effects of Ipriflavone
MK2
J
TNFRSF25
NH4Cl treatment prevents doxorubicin
Fluorescein
SU
MCE
KISS1
SM
STL1267 1429024
Phase II trial of oral rubitecan in previously treated pancreatic cancer patients PMID 15793221
1
Statin
MKK6 蛋白, Human (S207D, T211D, sf9, His)
CRBN ligand
A novel allosteric GCase modulator prevents Tau accumulation in GBA1WT and GBA1L444P/L444P cellular models PMID 40399377
Azosulfamide
Effect of extracellular pH on the potency of N
Effects of prolonged tremor due to penitrem A in mice PMID 3757822
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem
视黄醇结合蛋白 5（RBP5）基因
Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents PMID 21062107
2
[8
IL1RL1
Tyrphostin
mmu
Zinc finger
Tyrosinase
Targeting N6
cis
N
5,5′
(
Necrostatin 2 racemate 852391
In vitro anti
The use of modified primers to eliminate cycle sequencing artifacts PMID 10556322
Unguinol 36587
EBET
D
Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity PMID 32911199
Actions of tremorgenic fungal toxins on neurotransmitter release PMID 6108984
The experimental research of R
Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of Toxoplasma gondii tachyzoites in vitro and in vivo PMID 24366743
共967页
首页
上一页
788
787
786
785
784
783
782
781
780
779
778
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新