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CGP
Efficacy of Olorofim (F901318) against Aspergillus fumigatus, A. nidulans, and A. tanneri in Murine Models of Profound Neutropenia and Chronic Granulomatous Disease PMID 30885903
First
JZP
Famotidine
hsa
The chemical synthesis of metabolically stabilized 2
IL
Leukotriene B4
Inhibition of ACLY Leads to Suppression of Osteoclast Differentiation and Function Via Regulation of Histone Acetylation PMID 34155695
Design, synthesis and pharmacological evaluation of a novel PEG
Negative feedback exerted by cAMP
FGL1 蛋白, Human (HEK293, Fc)
NT
HIV
Xylitol induces cell death in lung cancer A549 cells by autophagy PMID 25650339
Bupropion 34911
Bepotastine 125602
An N,N
SW033291 promotes liver regeneration after acetaminophen
Saroglitazar, a novel PPARα/γ agonist with predominant PPARα activity, shows lipid
L
Evaluating the in Vitro Efficacy of Quassinoids from Eurycoma longifolia and Eurycoma harmandiana against Common Cold Human Coronavirus OC43 and SARS
Randomized Phase 0/I Trial of the Mitochondrial Inhibitor ME
Pam3CSK4
In vitro and in vivo studies of three antibiotic combinations against gram
Development of Fluorescent AF64394 Analogues Enables Real
CRBN ligand
NPD
Conversion of Quinazoline Modulators from Inhibitors to Activators of β
Mechanistic characterization of S 38093, a novel inverse agonist at histamine H3 receptors PMID 28336400
GPR91 mediates low shear stress
5
AhR agonist 7 3033281
Synthesis, Activity and Metabolic Stability of Non
Antiwrinkle
Simplified scalable synthesis of a water
Hedycoronen A 1383441
Isolation and cDNA cloning of a novel galanin
Topical anti
Location and Cell
Design, synthesis and biological evaluation of amphiphilic benzopyran derivatives as potent antibacterial agents against multidrug
EF
ANO1
MCE
Lipid Nanoparticle (LNP) Chemistry Can Endow Unique In Vivo RNA Delivery Fates within the Liver That Alter Therapeutic Outcomes in a Cancer Model PMID 36154076
Neuropeptide Y upregulates the adhesiveness of human endothelial cells for leukocytes PMID 1670626
Ozuriftamab 2460399
MRX
Methyl arachidate
DPP IV/hCA II
Distinct pharmacological and molecular properties of the acid
GE11 Peptide as an Active Targeting Agent in Antitumor Therapy A Minireview PMID 29271876
Antianginal effect of RS
Pentacosafluorotridecanoic Acid 72629
CRBN ligand
Lymphocyte
Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone
12
Tazobactam 89786
STAT3
Antitumor Activity of a Novel Sphingosine
SYBR green I chloride 2225748
Diverged nuclear localization of Werner helicase in human and mouse cells PMID 11420665
Cytotoxic lanostane triterpenoids from the fruiting bodies of Piptoporus betulinus PMID 28800422
Synthesis and Carbonic Anhydrase Inhibition Profiles of N
On the selective N
Patamostat hydrochloride 3031765
Cardioprotective role of azafrin in against myocardial injury in rats via activation of the Nrf2
丙戊酸 d<sub>6</sub>
Novel benzoylurea derivative decreases TRPM7 channel function and inhibits cancer cells migration PMID 39212541
Microsphere
Transthyretin
Bradykinin causes inhibition of methacholine
1,1,1,2
Identification of pH
Dibenzoxepinone hydroxylamines and hydroxamic acids dual inhibitors of cyclooxygenase and 5
Discovery of Novel MTA
N
Anti
Activation of PDE10 and PDE11 phosphodiesterases PMID 22105073
A novel Epac
CH 275 174688
Anxiolytic
Stomach
Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists PMID 25668616
Sterigmatocystine 10048
HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression PMID 24904118
Stelleralides D
Mcl
Xrn1
E722
二羟丙茶碱
Characterizing the role of porin mutations in susceptibility of beta lactamase producing Klebsiella pneumoniae isolates to ceftaroline and ceftaroline
Comparative Study of 5'
Synthesis and anti
OADS 5970
Fumaric acid
CRBN ligand
NAMPT Impairs Vascular Permeability in Periodontitis by Influencing FASN
Sensory nerve EP4 facilitates heterotopic ossification by regulating angiogenesis
Syringaldazine
Effects of 2
DPP (Dipeptidyl Peptidase)
Porcine brain natriuretic peptide
Propyl pyrazole triol 263717
Naph
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small
Cloning and expressional characterization of a novel galanin receptor. Identification of different pharmacophores within galanin for the three galanin receptor subtypes PMID 9405385
hsa
MCE
AT7519, A novel small molecule multi
Do changes in transglutaminase activity alter latent transforming growth factor beta activation in experimental diabetic nephropathy? PMID 20507850
MAO
D
CRBN ligand
A2073 2834742
hsa
Olaquindox 23696
DCZ19931, a novel multi
CRBN ligand
Discovery of small
Inhibiting effects of antipain on urethane
Development and characterization of biphenylsulfonamides as novel inhibitors of bone resorption PMID 17149877
Quinazoline
Efficacy and safety of cefepime a systematic review and meta
Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils PMID 2777377
BNP 抗体 (YA1000)(PBS only)（BNP Antibody (YA1000)(PBS only)）
SMARCA5 Human Pre
Effects of retinoid beta
Genome
A
Discovery of IACS
AH 8532
Biotin
Depletion of UDP
Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo PMID 7495753
MCE
Benzyl 2
Discovery of Roblitinib (FGF401) as a Reversible
Osthenol 484
IMU
Estradiol and its metabolites 4
2,3,4,5
Design, Synthesis, and Insecticidal Evaluation of N
Translational potential of the ghrelin receptor agonist macimorelin for seizure suppression in pharmacoresistant epilepsy PMID 34157194
全球办事处
DHPCC
Astrophloxine 14696
Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells PMID 19383925
Effect of acyclic monoterpene alcohols and their derivatives on TRP channels PMID 25455494
Conformationally constrained farnesoid X receptor (FXR) agonists heteroaryl replacements of the naphthalene PMID 21256005
Immunogenic Comparison of Nucleic Acid
APETx2 713544
Dihydrozeatin riboside
CRBN ligand
CRBN ligand
Isolation and characterization of pleurocidin, an antimicrobial peptide in the skin secretions of winter flounder PMID 9115266
CNI103 2366279
含 PNKD 金属
LY210073 148291
DMG
KGF 抗体 (YA323)（KGF Antibody (YA323)）
Cobitolimod 1226822
Tuclazepam 51037
Flupenthixol decanoate 30909
Thalidomide
O
Anti
MCE
8
A naturally occurring variant of SHLP2 is a protective factor in Parkinson's disease PMID 38167865
An agonistic anti
Bioactive 2
KLRG1 蛋白, Cynomolgus (HEK293, His)
A natural flavagline derivative A2073 inhibits the proliferation of erythroleukemia cells by targeting the MAPK, PI3K, NF
Sebacamic acid 6249
7
HA
Synthesis and biological evaluation of negative allosteric modulators of the Kv11.1(hERG) channel PMID 26519929
Fibroblast
Unprecedented synthesis, in vitro and in vivo anti
Morphothiadin mesylate 1646361
FGFR
Inhibitory effects of furoquinoline alkaloids from Melicope confusa and Dictamnus albus against human phosphodiesterase 5 (hPDE5A) in vitro PMID 16042076
CRBN ligand
CRBN ligand
Sobrerol Improves Memory Impairment in the Scopolamine
STAT3
MCE
Interfacial behavior of cholesterol, ergosterol, and lanosterol in mixtures with DPPC and DMPC PMID 18515391
MR imaging of hepatocellular carcinoma prospective intraindividual head
Acid Red 26 3761
Docarpamine 74639
Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back
SELL
Tavilermide 263251
(Z)
Site
mmu
Male olive fruit fly attraction to synthetic sex pheromone components in laboratory and field tests PMID 24309970
Isosorbide 2
Basic cell culture conditions PMID 17623916
5,7,8
MCE
Chemical phosphorylation amidite 202284
Action of pancreatic polypeptide on rat pancreatic secretion in vivo and in vitro PMID 2413769
Effects of GR
ATG12
The Effects of 2'
5
Effects of steroid 5alpha
Optimizing TRPM4 inhibitors in the MHFP6 chemical space PMID 30708257
MCE
Ciproxifan, a histamine H₃
Human Saliva
Calcium
(S,R,S)
Identification of a novel gene, DZIP (DAZ
MCE
The crosstalk role of CDKN2A between tumor progression and cuproptosis resistance in colorectal cancer PMID 38888512
Differential Free Intracellular Calcium Release by Class II Antiarrhythmics in Cancer Cell Lines PMID 30655298
mmu
Ganoderic acid GS
T cells compete by cleaving cell surface CD27 and blocking access to CD70
Two
DKK
Synthesis and biological evaluation of novel anticancer bivalent colchicine
Separation and quantitative determination of acecarbromal, carbromal, and bromisoval as well as their main metabolites by means of high
Superoxide dismutase
AT7519 844442
Recanaclotide (IW
Avilamycin A 69787
CRBN ligand
SHLP2 1191923
ABT
Ara
L
The small
Ascochlorin 26166
Neoflavonoids as potential osteogenic agents from Dalbergia sissoo heartwood PMID 24803361
Fragment
ABC99 2331255
Rosuvastatin impurity 54 (Standard)
Shedding Light on the Diversity of Surfactant Interactions with Luminol Electrochemiluminescence for Bioanalysis PMID 31524378
BG
[Leu31, Pro34]neuropeptide Y a specific Y1 receptor agonist PMID 2153286
Tricyclohexylphosphine 2622
C29 363600
Prednisolone PMID 1254891
MCE
Cytotoxic bromoindole derivatives and terpenes from the Philippine marine sponge Smenospongia sp PMID 12440734
Rhoifolin from Plumula Nelumbinis exhibits anti
TERC suppresses PD
KP
POMA analyses as new efficient bioinformatics' platform to predict and optimise bioactivity of synthesized 3a,4
MCE
5
Cyclacidin 749
POLA1 inhibitor 1 2217671
NPC
A new look at the respiratory stimulant doxapram PMID 17227289
ESCRT machinery is required for plasma membrane repair PMID 24482116
5
HY
Butyrylcholinesterase for protection from organophosphorus poisons catalytic complexities and hysteretic behavior PMID 20004171
Napyradiomycin A2 111216
Characterisation of UBP296 a novel, potent and selective kainate receptor antagonist PMID 15165833
Murraol 109741
Imifoplatin 1339960
Role of c
SPNS 溶血脂转运蛋白 3，1
Enterococcus hirae
Polydatin alleviates mycoplasma pneumoniae
Design, performance, processing, and validation of a pooled CRISPR perturbation screen for bacterial toxins PMID 39487259
Design, synthesis, enzyme
Simultaneous Analysis of Fenthion and Its Five Metabolites in Produce Using Ultra
Synthesis and antitumor
The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts PMID 26325604
Mitigating the resistance of MCF
Synthesis and identification of a selective FGFR2 degrader with potent antiproliferative effects in gastric cancer PMID 39167894
A Family of Antibiotics That Evades Resistance by Binding Polyprenyl Phosphates PMID 37937847
Investigation of the structural requirements of K
JAK
SERPINF2
Inhibition of prostaglandin biosynthesis by triynoic acids PMID 959584
Shikonin Attenuates Acetaminophen
Carbenicillin disodium 4800
Mal
CRBN ligand
Guaianolides and a seco
Co
Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole
ATR
Disorazol A1, a highly effective antimitotic agent acting on tubulin polymerization and inducing apoptosis in mammalian cells PMID 15104246
Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver PMID 32415122
D
Comparison on phenolic compounds and antioxidant properties of cabernet sauvignon and merlot wines from four wine grape
AH 6809 33458
Diphenicillin 304
MNK, mTOR or eIF4E
FZD8
Suriclone and diazepam in the treatment of neurotic anxiety. A double
Potent and selective agonism of the melanocortin receptor 4 with MK
Falandioside B 1809429
The glutamate transport inhibitor DL
CDD
PLD6 蛋白, Human
CRBN ligand
Semax acetate 2828433
PKC eta 抗体 (YA126)（PKC eta Antibody (YA126)）
Auristatin S 3028453
Icariside II induces rapid phosphorylation of endothelial nitric oxide synthase via multiple signaling pathways PMID 36312762
Characterization of functional neuropeptide Y receptors in a human neuroblastoma cell line PMID 2164571
DPH 484049
Discovery of cloxiquine derivatives as potent HDAC inhibitors for the treatment of melanoma via activating PPARγ PMID 39522492
Neuropathiazol induces neuronal
Peptide T[4
Antitumor activity of a derivative of mitomycin, 7
Argireline acetate 2484708
Bis(1H
TP
Ndufb8
Binding characteristics of SSR180575, a potent and selective peripheral benzodiazepine ligand PMID 14550272
Serum Quantitative Proteomic Analysis Reveals Soluble EGFR To Be a Marker of Insulin Resistance in Male Mice and Humans PMID 29028997
Equipotent inhibition of fatty acid amide hydrolase and monoacylglycerol lipase
Role of Osteogenic Growth Peptide (OGP) and OGP(10
MDM2/4
Design and synthesis of human immunodeficiency virus entry inhibitors sulfonamide as an isostere for the alpha
Synthesis and biological evaluation of echinomycin analogues as potential colon cancer agent PMID 38561454
CP
Calcitonin (chicken) 100016
SMYD2 promotes tumorigenesis and metastasis of lung adenocarcinoma through RPS7 PMID 33935284
MAO
BMS
Specific PGF(2alpha) receptor (FP) antagonism and human uterine contractility in vitro PMID 16045514
Safety and efficacy of ponceau 4R for cats, dogs and ornamental fish PMID 32625852
Tetanus Toxin (830–844)
Geniposide modulates GSK3β to inhibit Th17 differentiation and mitigate endothelial damage in intracranial aneurysm PMID 39180344
ALK
Mechanism of action of lomefloxacin PMID 2168142
Lumigolix 1709823
(R)
JQ1
24( S),25
SPV106 1036939
Expanding the strategies in natural product studies of marine
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics PMID 28649697
Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus PMID 2614420
QX
Azide
Suramin a potent inhibitor of the reverse transcriptase of RNA tumor viruses PMID 92362
Salt
Adenoregulin 149260
[Protective action of blumeatin against experimental liver injuries] PMID 8249641
CRBN ligand
[Rh(Cp
A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet
DNP
S
Valganciclovir a review of its use in the management of CMV infection and disease in immunocompromised patients PMID 15819597
Diversity, Mechanisms, and Significance of Macrophage Plasticity PMID 31530089
CLEC9A 蛋白, Mouse (HEK293, Fc)
Anti
PDE9
BIN
Minaprine dihydrochloride 25953
CCR4
(rac)
Rpl27a
GRK5
DLinDMA 871258
Anti
An allosteric pan
Chinese gallotannin 5424
Integration Capacity of Human Induced Pluripotent Stem Cell
MCE
Synthesis, spectroscopic characterization and DNA nuclease activity of Cu(II) complexes derived from pyrazolone based NSO
AB
Bakuchiol mitigates colitis through GPR120 activation PMID 40085989
L
1
CRBN ligand
Procyanidin B2 inhibits NLRP3 inflammasome activation in human vascular endothelial cells PMID 25450671
Biosynthesis of the 5
TNKS1/2
MCE
CAY10698 684236
Erythropoietin Promotes Infection Resolution and Lowers Antibiotic Requirements in E. coli
Mal
Sosimerasib 2839563
SKF82958, a dopamine D1 receptor agonist, disrupts prepulse inhibition in the medial prefrontal cortex and nucleus accumbens in C57BL/6J mice PMID 38567425
Z
Bifunctional Inhibition of Botulinum Neurotoxin A Protease Unexpected Active Site Inhibition Enhances Covalent Targeting of an Allosteric Site PMID 40223217
4'
Tubulin inhibitor 17 2839151
Ioxynil and diethylstilbestrol disrupt vascular and heart development in zebrafish PMID 30685453
CRBN ligand
CRBN ligand
Identification of a Novel TRPM8 Agonist from Nutmeg A Promising Cooling Compound PMID 28740604
N
Stilbostemin B 162411
4'
Quinelorane
Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1 PMID 15576403
Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom PMID 11018665
FA2B glycan (G0B), 2
Bis(tri
Absolute bioavailability and metabolism of aceclofenac in rats PMID 24633464
Rilunermin alfa 2254278
BMS
Structure
Discovery of a Potent and Selective Fragment
Glutaryl
Gartisertib 1613191
OXi8007 288847
Propyl gallate induces cell death in human pulmonary fibroblast through increasing reactive oxygen species levels and depleting glutathione PMID 38438412
Fmoc
ML
Comparative in vitro activity of cefpodoxime against anaerobes other than Bacteroides fragilis PMID 1800380
TAF1
CRBN ligand
LTB4 antagonist 2 2929239
Geissoschizine methyl ether 60314
5'
Discovery of novel anti
Methyllucidone 19956
Peptides and aptamers targeting HSP70 a novel approach for anticancer chemotherapy PMID 21224349
DOTA
CRBN ligand
Oral efficacy of a leukotriene B4 receptor antagonist in colitic cotton
CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay PMID 18855964
The effect of different doses of cisplatin on the pharmacokinetic parameters of cefepime in mice PMID 16803647
Positive Allosteric Modulation of the Calcium
Eriocalyxin B inhibits nuclear factor
Alendronate
Advances in Saponin Diversity of Panax ginseng PMID 32751233
XP13512 [(+/
RepSox
Aβ/tau aggregation
USP28
Synthesis and biological evaluation of benzofuran piperazine derivatives as potential anticancer agents PMID 37557926
Zelavespib 873436
Trihydroxyflavones with antioxidant and anti
Selective self
MCE
Nitro blue tetrazolium chloride 298
RK
TRPV4
CMX
ALV
Tumor cellular proteasome inhibition and growth suppression by 8
Effects of acetate
Potential role of tissue transglutaminase in glaucoma filtering surgery PMID 16936095
Valsartan benzyl ester 137863
Chronic administration of Tat
Nortriterpenoids from Schisandra lancifolia PMID 16643044
FLT3
Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC PMID 40060528
7,7
Anti
Red blood cells in hemorrhagic shock a critical role for glutaminolysis in fueling alanine transamination in rats PMID 29296771
CTAP 103429
Clopidogrel impurity 10 90055
Acetyl Lysine 抗体 (YA6425)（Acetyl Lysine Antibody (YA6425)）
(2S,4S)
Projections from subfornical organ to bed nucleus of the stria terminalis modulate inflammation
An endogenous capsaicin
MCE
Neuroprotective efficacy and therapeutic window of Forsythoside B in a rat model of cerebral ischemia and reperfusion injury PMID 20470770
Hydroxybupropion 92264
dl
Veratramine ameliorates pain symptoms in rats with diabetic peripheral neuropathy by inhibiting activation of the SIGMAR1
Effect of cupric sulfate on the prophylactic efficacy of 2
MCE
5,6
Tricyclazole 41814
Design, synthesis, and biological evaluation of novel and highly potent peptides targeting syntenin PMID 40020425
Inhibition of gp130 alleviates LPS
ITGB1 alleviates osteoarthritis by inhibiting cartilage inflammation and apoptosis via activating cAMP pathway PMID 37941009
BNP 抗体 (YA1000)（BNP Antibody (YA1000)）
The Total Synthesis of Inostamycin A PMID 26800259
Effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)
G256 134867
Tropisetron But Not Granisetron Ameliorates Spatial Memory Impairment Induced by Chronic Cerebral Hypoperfusion PMID 32797381
mmu
4
MG
CGP 36216 is a selective antagonist at GABA(B) presynaptic receptors in rat brain PMID 11274998
Development of a Cyclic Peptide Inhibitor of the p6/UEV Protein
MC
Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice PMID 16354910
Tetramethylpyrazine inhibits neutrophil extracellular traps formation and alleviates hepatic ischemia/reperfusion injury in rat liver transplantation PMID 34273405
H2TMpyP
Epipterosin L 2'
The Development of BTK Inhibitors A Five
Quinolinic acid
1,4
Effect of conjugates of all
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