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mmu
Small
sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death PMID 35798718
Sitagliptin ameliorates diabetic nephropathy by blocking TGF
The action of 2 4
Biotin
Abz
Succinic acid
Deciphering the Role of NLRP
MOF
5
CRBN ligand
TRAP
Chloropropylate 5836
Benzothiazolyl and Benzoxazolyl Hydrazones Function as Zinc Metallochaperones to Reactivate Mutant p53 PMID 33538587
C1s Rat Pre
MCE
Paics Mouse Pre
Raloxifene
A population pharmacokinetic
Glycine Oxidase H244K, Bacillus subtilis
MSX
Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF
MCE
CD24 Protein
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway Screening of natural products using WGCNA and CMAP platforms PMID 38924866
The glutamate receptor antagonist ifenprodil inhibits hepatitis E virus infection PMID 39360823
Suppressive effect of topically applied CX
The hydrolysis of the prostaglandin analog prodrug bimatoprost to 17
HOOC
Azido
1,12
ALK5
The effect of the fluorescent probe, 3,3'
Lipid
Combined targeting of G protein
Inhibitors of V
Cepadacursen sodium 2252375
Antagonism of the nicotine
(±)
Fructose
Sodium ionophore VI 80403
Estropipate 7280
Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells PMID 26090665
Antiinflammatory peptides (antiflammins) inhibit synthesis of platelet
KIRA9 2922507
Glycerophosphoinositol choline
Transforming growth factor
核孔蛋白 214（NUP214）基因
CRNN
Correlation of Glycosylated Hemoglobin Levels with Histological and Ultrasound Characteristics of the Carotid Plaque in Diabetic and Nondiabetic Patients PMID 31344464
Enhanced design and formulation of nanoparticles for anti
Effect of N
Interleukin
The analgesic NSAID lornoxicam inhibits cyclooxygenase (COX)
Havcr2 Mouse Pre
USP11 蛋白, Human (sf9, GST)
LDC7559 2407782
Single
KIR2DL3 蛋白, Human (HEK293, His
Multiple Beneficial Effects of Aloesone from Aloe vera on LPS
Proton
Fmoc
Kansuinine A and Kansuinine B from Euphorbia kansui L. inhibit IL
The GntR/VanR transcription regulator AlkR represses AlkB2 monooxygenase expression and regulates n
Pole2
MAD1L1 抗体 (YA2449)（MAD1L1 Antibody (YA2449)）
IL
Benzothiazole derivatives as histone deacetylase inhibitors for the treatment of autosomal dominant polycystic kidney disease PMID 38653068
LS
CHST5 Human Pre
Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation PMID 32795399
CXC chemokine ligand 4 (Cxcl4) is a platelet
Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress
The safety and efficacy of Guluronic acid (G2013) in ankylosing spondylitis A randomized controlled parallel clinical trial PMID 31003148
Comparison of Lornoxicam and Rofecoxib in Patients with Activated Osteoarthritis (COLOR Study) PMID 17516707
The potential benefits of nicaraven to protect against radiation
Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions PMID 22554647
Synthesis and biophysical characterization of chlorambucil anticancer ether lipid prodrugs PMID 19402667
TRAF2 和 NCK 相互作用激酶（Tnik）基因
Madecassoside prevents Aβ(25
Carboxyamidotriazole inhibits oxidative phosphorylation in cancer cells and exerts synergistic anti
Boc
Abnormally short serum half
Ethofumesate
p60c
Technetium
VTN Human Pre
Interleukin
Igfbp6 Mouse Pre
Isobavachalcone enhances sensitivity of colistin
Fscn1 Rat Pre
Potential for long
Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β
DHX9
(S)
MI
FXR agonist 17
Triptonodiol 117456
基质金属肽酶 17（Mmp17）基因
PU 23 817635
BATCP
Studies on New Components and Stereochemistry of Diterpenoids from Trypterygium wilfordii PMID 17265278
N
Norverapamil
An orally available non
Liriopesides B 87425
Oleosin 蛋白, Glycine max (Cell
FAU Human Pre
CSRP1 蛋白, Human (His)
Hepatic TNFRSF12A promotes bile acid
Carvedilol
Intracellular association of the protein product of the c
Trimethylsulfonium
Fura
The origin of quantal size variation vesicular glutamate concentration plays a significant role PMID 17360928
Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice PMID 31748578
Synthesis, characterization, molecular docking and molecular dynamics simulations of novel 2,5
Site
Successful treatment of Bowen's disease with topical maxacalcitol PMID 22281814
(2R)
High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL
2
Ifinatamab deruxtecan 2484870
1,3,5
含 423 域 1（FYTTD1）基因
Protease activated receptor 4 (PAR4) antagonists Research progress on small molecules in the field of antiplatelet agents PMID 33049608
中心体蛋白 192（CEP192）基因
J 628 65323
PD
RHPN1 Human Pre
N
HSGN
hsa
hsa
Recent Developments of Carboxymethyl Cellulose PMID 33924089
Carbazole
MCE
DHX9
Dysf
Effects of a novel glycogen synthase kinase
SBP
ME
Progress of Ferroptosis in Ischemic Stroke and Therapeutic Targets PMID 38393376
Clock
Screening of Small
An orally active plant Rubisco
Infigratinib phosphate 1310746
CD206/MMR 蛋白, Human (HEK293, His)
A novel branched galacturonan from Gardenia jasminoides alleviates liver fibrosis linked to TLR4/NF
Arf6
RPL13 Human Pre
Neutralization of plasminogen activator inhibitor I (PAI
L
A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep PMID 19486034
Carubicin hydrochloride 52794
High soluble endoglin levels regulate cholesterol homeostasis and bile acids turnover in the liver of transgenic mice PMID 31299237
Inhibition of neurogenic and thromboxane A2
A Simple and Sensitive LC
Calcitonin gene
Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis PMID 22882828
Exposure to amitraz, fipronil and permethrin affects cell viability and ABC transporter gene expression in an Ixodes ricinus cell line PMID 30064465
BAY
DNA
Solasonine promotes ferroptosis of hepatoma carcinoma cells via glutathione peroxidase 4
aspirin metabolism
A novel Monoclonal Antibody against Notch1 Targets Leukemia
The ubiquitin ligase Pellino1 targets STAT3 to regulate macrophage
Simultaneous measurement of 25
ROS inducer 4 2959444
Sesquiterpenoids with diverse carbon skeletons from the roots of Cichorium glandulosum and their anti
FR
Straub& 039;s tail
Chlorothalonil exposure compromised mouse oocyte in vitro maturation through inducing oxidative stress and activating MAPK pathway PMID 38367607
Tanshinone IIA alleviates acute ethanol
MCE
PK/PD investigation of antiviral host matriptase/TMPRSS2 inhibitors in cell models PMID 39025978
Identification and characterization of PKF118
Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation PMID 15131002
Phenyltriazole
AMPK alleviates high uric acid
14
Photopharmacological control of bipolar cells restores visual function in blind mice PMID 28581442
1
Bis(m
Climbazole is a new potent inducer of rat hepatic cytochrome P450 PMID 11552297
1
Astrocytic scar restricting glioblastoma via glutamate
Donor Lymphocyte
Vitamin D
Succinic Acid
A reactive oxygen species
Asymmetric Synthesis of Oxygenated Monoterpenoids of Importance for Bark Beetle Ecology PMID 33170693
Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post
Reprogramming of glucose metabolism Metabolic alterations in the progression of osteosarcoma PMID 38288377
Curcumin suppresses NLRP3 inflammasome activation by inducing autophagy to alleviate neuropathic pain in rats PMID 40900270
Corticosterone secretion
Distinct toll
Next
Synthesis and evaluation of triazole
Toll
Creatine a dietary supplement and ergogenic aid PMID 10079702
A general prodrug nanohydrogel platform for reduction
GFRA1 Human Pre
PK
Evaluation of the diuretic activity in two Mexican medicinal species Selaginella nothohybrida and Selaginella lepidophylla and its effects with ciclooxigenases inhibitors PMID 25645190
Pharmacokinetics and pharmacodynamics of single and multiple doses of the glucagon receptor antagonist LGD
IL36RN Human Pre
PLGA
Pharmacological profile of a high affinity dipeptide NK1 receptor antagonist, FK888 PMID 1282073
Anti
ZM 306416 690206
Utrophin activator
PAICS Human Pre
nAChR antagonist 3
Sarcosine Oxidase, E.coli
Wallichinine (Wallichinin，南藤素)
Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex
Col4a2 Mouse Pre
运输蛋白颗粒复合物亚基 2（TRAPPC2）基因
Disposition, metabolism, and excretion of the anticancer agent crisnatol in the rat PMID 1676660
DPYSL5 Human Pre
Human pulmonary microvascular endothelial cells respond to DAMPs from injured renal tubular cells PMID 38962184
Integrated Microbiome and Metabolome Analysis Reveals Hypothalamic
Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity PMID 32223141
Discovery, design and synthesis of the first reported potent and selective sphingosine
Inhibition of the gastric H,K
Disruption of mitochondrial energy metabolism is a putative pathogenesis of Diamond
Alkaloids from Chelidonium majus and their inhibitory effects on LPS
Cyclosporin A is unable to inhibit carboxyatractyloside
Mcl
Phase II trial of carboxyamidotriazole in patients with relapsed epithelial ovarian cancer PMID 14645425
[Etimizol absorption from the small intestine in dogs the dependence on dosage] PMID 3801627
New trypanocidal hybrid compounds from the association of hydrazone moieties and benzofuroxan heterocycle PMID 18547811
Rapid Screening and Structural Characterization of Antioxidants from the Extract of Selaginella doederleinii Hieron with DPPH
6
Metabolites in safety testing assessment in early clinical development a case study with a glucokinase activator PMID 25142735
Tivumecirnon 2174938
Ndufa8 promotes white fat Browning by improving mitochondrial respiratory chain complex I function to ameliorate obesity by in vitro and in vivo PMID 39127135
The glucose
Immune regulation by glucocorticoids can be linked to cell type
Fibroblast growth factor 21 attenuates ventilator
N
Rhein
Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy PMID 27535971
Protection from liver fibrosis by a peroxisome proliferator
Protein Phosphatase
Rac1 Inhibitor W56
Whole
Sp
Anti
Discovery of the Human Immunodeficiency Virus Type 1 (HIV
CXCL16 蛋白, Canine (HEK293, Fc)
The Emerging Mycotoxin 2
Discovery, Optimization, and Preclinical Pharmacology of EP652, a METTL3 Inhibitor with Efficacy in Liquid and Solid Tumor Models PMID 39883878
Inhibition of Hypoxia
GDNF
Natural Tr1
2
Rolofylline 136199
烟碱型乙酰胆碱受体
Glucocorticoids Impair the 7α
KRP
Antimicrobial and Antioxidant Secondary Metabolites from Trifolium baccarinii Chiov. (Fabaceae) and Their Mechanisms of Antibacterial Action PMID 34722760
Profiling of FSHR negative allosteric modulators on LH/CGR reveals biased antagonism with implications in steroidogenesis PMID 27424143
Darovasertib 1874276
1'
ICG PEG DSPE (MW 2000)
[Effect of palonidipine hydrochloride (TC
Propargyl
Integrin α2β1 plays an important role in the interaction between human articular cartilage
AM12 2387510
GPR158 蛋白, Human (HEK293, GFP, FLAG, His)
Ribocil 1381289
Effects of meclofenoxate and citicholine on learning and memory in aged rats PMID 3129903
VU0652835 1848252
DMPPD
LSN3074753 1455031
Trpvicin
STUB1 抗体 (YA2096)（STUB1 Antibody (YA2096)）
Anti
Iron deficiency alters expression of genes implicated in Alzheimer disease pathogenesis PMID 18723004
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma PMID 40739706
The toxicity of a fluorinated
Determination of coenzyme Q10, coenzyme Q9, and melatonin contents in virgin argan oils comparison with other edible vegetable oils PMID 22007968
IL3RA
Design, synthesis, and pharmacological evaluation of indole
富半胱氨酸的分泌蛋白 3（CRISP3）基因
P19P 2512843
Slc6a14 Rat Pre
Farnesoid X Receptor Activation Protects Liver From Ischemia/Reperfusion Injury by Up
non
Rapamycin relieves the cataract caused by ablation of Gja8b through stimulating autophagy in zebrafish PMID 33472493
Synthesis of chimeric tetrapeptide
PPM1G
BRCA2
Sirolimus treatment induces dose
Gut neurotoxin p
Neuromedin S regulates goat ovarian granulosa cell proliferation and steroidogenesis via endoplasmic reticulum Ca2+
Niludipine 22609
DA 1686
Syntheses of conformationally restricted benzopyran based triarylethylenes as growth inhibitors of carcinoma cells PMID 29054359
BB
RESORUFIN BUTYRATE AND INDOXYL ACETATE AS FLUOROGENIC SUBSTRATES FOR CHOLINESTERASE PMID 14230702
A rapid and efficient technique for liposomal and nonliposomal drug pharmacokinetics studies using magnetic nanoprobes and its application to leakage kinetics of liposomes PMID 30391033
Voltage
Sapintoxin D 80998
Highly Selective and Potent Thiophenes as PI3K Inhibitors with Oral Antitumor Activity PMID 24900269
MAT2A
Acetonitrile
Benzoylphenylurea sulfur analogues with potent antitumor activity PMID 16570932
Urocanic acid
DBHDA 99584
Pyroptosis of pulmonary fibroblasts and macrophages through NLRC4 inflammasome leads to acute respiratory failure PMID 40158217
Geometric Constraints Regulate Energy Metabolism and Cellular Contractility in Vascular Smooth Muscle Cells by Coordinating Mitochondrial DNA Methylation PMID 36106364
Design, Synthesis, and Biological Evaluation of Novel Evodiamine Derivatives as Potential Antihepatocellular Carcinoma Agents PMID 35639640
Trametinib, a first
6
GCSH 蛋白, Human (His)
In silico λ
Caspase
CHMFL
6
Actn1
New antifungals selected by molecular topology PMID 9873584
1
NFE2 样 bZ IP 转录因子 2（Nfe2l2）基因
Lysosomes
Sulforaphane homologues Enantiodivergent synthesis of both enantiomers, activation of the Nrf2 transcription factor and selective cytotoxic activity PMID 25299679
4,5
Transient Receptor Potential Melastatin 8, a sensor of cold temperatures mediates expression of cyclin
Calycosin
IS4 3067986
hsa
Modulation of amyloid precursor protein expression reduces β
PCSK9 ligand 2 3039841
AMG319 1608125
Dysregulated glucuronic acid metabolism exacerbates hepatocellular carcinoma progression and metastasis through the TGFβ signalling pathway PMID 35979621
2
Rasagiline
4,4'
Punica granatum fruit extract
GR 92549
LncRNA AGAP2 antisense RNA 1 stabilized by insulin
In
Mitochondrial targeting derivatives of honokiol enhanced selective antitumor activity in NCI
Im
Influence of different histamine receptor agonists and antagonists on apomorphine
Use of Xanthinol Nicotinate as a co
Synthesis and cytotoxic activity of novel derivatives of 4'
6
Pharmacokinetics and metabolism of naproxen in children PMID 7151646
粘蛋白 20，细胞表面相关（MUC20）基因
Velufenacin (DA
BMS
W2476 ameliorates β
Silodosin a new subtype selective alpha
CLEC14A Human Pre
Indocarbazostatin B 334831
ATV2301 3049172
N
AL
Carbamazepine
(S)
Bisphenol A
The 5
Relationship between the restriction of food intake and Melitracen, an antidepressant, in the rat PMID 5587525
Z
Spectroscopic characterization of the calmodulin
TP
Antiplatelet effect of 2
Semi
凋亡抑制因子 5（API5）基因
Afferent
原子同系物 A（ATOSA）基因
Fozivudine tidoxil 141790
A4galt Mouse Pre
MCE
Placebo
self
Isoindoline scaffold
SRT3025
QS
Free energy perturbation studies on binding of A
SIK2
Lithocholic acid inhibits P2X2 and potentiates P2X4 receptor channel gating PMID 32652201
DBCO
KAG
TP0586532 2427584
Antisauvagine
Sequence
1,2,4
(Rac)
The discovery and the structural basis of an imidazo[4,5
Antibacterial activity and mechanisms of D
Effects of thyrotropin
The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8+ T cells PMID 38650034
Essential role of calcium in vascular endothelial growth factor A
Revisiting microtubule targeting agents α
Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites PMID 1650211
Effects of various coumarins from roots of Angelica dahurica on actions of adrenaline, ACTH and insulin in fat cells PMID 6287510
脂联素受体 1（ADIPOR1）基因
Comparative Evaluation and Profiling of Chemical Tools for the Nuclear Hormone Receptor Family 2 PMID 40046426
Gdf7 Rat Pre
Platycodin D attenuates diabetic renal ischemia/reperfusion injury by enhancing mitophagy and suppressing MAPK/NF
Toyaburgine, a Synthetic N
Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist PMID 24135724
Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment PMID 30611118
Preparation and characterization of pH
Fibronectin 蛋白, Human (Biotinylated, His
Vanin
Antioxidant properties of Aloe vera components a DFT theoretical evaluation PMID 31357895
Optimization of a Piperidine CD4
GDF8 Promotes the Cell Invasiveness in Human Trophoblasts by Upregulating the Expression of Follistatin
HD
UNC9994 hydrochloride 2108826
Trabedersen, a TGFbeta2
前列腺素 I2 受体（PTGIR）基因
AM095 free acid 1228690
CD44 and αV
兔多克隆抗体定制服务
Antioxidant compounds from Chaerophyllum hirsutum extracts PMID 15351116
A novel highly potent autotaxin/ENPP2 inhibitor produces prolonged decreases in plasma lysophosphatidic acid formation in vivo and regulates urethral tension PMID 24747415
Photochemical cross
MK
Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia PMID 32386594
Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator
Mastoparan B 137354
ADCY4 inhibits cAMP
Gabapentin, A GABA analogue, enhances cognitive performance in mice PMID 21296127
S
A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis PMID 33777677
Conformation
RNA
The protective effects of pretreatment with resveratrol in cyclophosphamide
Spiral molecules with antimalarial activities A review PMID 35461019
Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells PMID 26675349
COVID
STK33/ERK2 signal pathway contribute the tumorigenesis of colorectal cancer HCT15 cells PMID 30760631
IL
Fibronectin 蛋白, Human (571a.a, HEK293, His)
CXCL14 Promotes a Robust Brain Tumor
Vitamin D Binding Protein 抗体 (YA009)(PBS only)（Vitamin D Binding Protein Antibody (YA009)(PBS only)）
m
Regulating triacylglycerol cycling for high
Methyl green. A DNA major
PROTAC MALT1 Degrader
Monoolein, isolated from Ishige sinicola, inhibits lipopolysaccharide
TLR8
Fusobacterium nucleatum
MS83 2762181
Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp
Sophoricoside enhances reparative macrophage polarization to promote cardiac repair postmyocardial infarction through PPAR
B4galt4 Rat Pre
纽蛋白（VCL）基因
Selective Small
Lomifylline 10226
GPN3 Human Pre
Initial SAR studies on apamin
Novel substituted aminothiazoles as potent and selective anti
沉默信息调节因子 2 相关酶类 6（SIRT6）基因
PROTAC BRD4 Degrader
1A
Epm2a
Orphan G protein
Inhbb
(S)
Adipor1 Mouse Pre
N
Characterization of the clotting activities of structurally different forms of activated factor IX. Enzymatic properties of normal human factor IXa alpha, factor IXa beta, and activated factor IX Chapel Hill PMID 3871202
Tramiprosate protects neurons against ischemic stroke by disrupting the interaction between PSD95 and nNOS PMID 24769446
Antimycobacterial compounds from Piper sanctum PMID 15620234
9
Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis PMID 10090426
(±)
NPY 蛋白, Human (HEK293, His)
Regulation of Osteogenic Differentiation of hBMSCs by the Overlay Angles of Bone Lamellae
Discovery of Benzo[cd]indol
Synthesis and structure
Se
Kinetic modulation of guinea
B4GALT3 Human Pre
Glycine
Enhanced RIPK3 kinase activity
2
KB528
Pharmacological properties of GABAA receptors containing gamma1 subunits PMID 16272224
Inhibitory effects of reumycin produced by Streptomyces sp. TPMA0082 on virulence factors of Pseudomonas aeruginosa PMID 40195206
Novel pyridine
Involvement of an increased spinal TRPV1 sensitization through its up
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