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NVP
Isolation of adenosine, iso
multidrug
Mechanism of MEK inhibition determines efficacy in mutant KRAS
Identifying PTAFR as a hub gene in atherosclerosis implications for NETosis and disease progression PMID 39709510
UP163 591242
Suppression of homeobox transcription factor VentX promotes expansion of human hematopoietic stem/multipotent progenitor cells PMID 22791709
Ki67 抗体 (YA001)（Ki67 Antibody (YA001)）
STAMBPL1, transcriptionally regulated by SREBP1, promotes malignant behaviors of hepatocellular carcinoma cells via Wnt/β
Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase PMID 28688274
2,3,5
RNF8 抗体 (YA1344)（RNF8 Antibody (YA1344)）
GK718
PF429242 dihydrochloride 2248666
FGF
MgFe
Inhbc Rat Pre
In vitro activities of novel nonfluorinated quinolones PGE 9262932 and PGE 9509924 against clinical isolates of Staphylococcus aureus and Streptococcus pneumoniae with defined mutations in DNA gyrase and topoisomerase IV PMID 12019071
AMPK regulates ARF1 localization to membrane contact sites to facilitate fatty acid transfer between lipid droplets and mitochondria PMID 40825999
CDC23 Human Pre
AN15368 2152662
BI
AZD4877 758722
mmu
KDM2/7
Moflomycin 107430
Nitric oxide (NO) releasing poly ADP
Anti
Dragons blood extract 90028
AdipoRon promotes diabetic fracture repair through endochondral ossification
Cigarette smoke extracts induce apoptosis in Raw264.7 cells via endoplasmic reticulum stress and the intracellular Ca2+/P38/STAT1 pathway PMID 34560245
MMP2 抗体 (YA3704)（MMP2 Antibody (YA3704)）
FOXD1 promotes EMT and cell stemness of oral squamous cell carcinoma by transcriptional activation of SNAI2 PMID 34348789
TCMDC 136230
Antidesmone, a unique tetrahydroquinoline alkaloid, prevents acute lung injury via regulating MAPK and NF
Theaflavin
Skin Cancer
Classical HDACs in the regulation of neuroinflammation PMID 34509559
NPD
Karenitecin
Innovative use of σ and π electron acceptors in the development of three high throughput 96
2
mold growth
A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)
NAP1L5 facilitates pancreatic ductal adenocarcinoma progression via TRIM29
U
7(18)
Small fluorescence
CDK9
Triethanolamine borate 283
Cholesterol metabolism regulated by CAMKK2
Comparative in vitro activities of nemonoxacin (TG
High
CFAP45 Human Pre
STAT3 mediated upregulation of C
Characterization of zolbetuximab in pancreatic cancer models PMID 30546962
di
Boceprevir
PFI
1
(+/
F7
Pancreatic cancer induces muscle wasting by promoting the release of pancreatic adenocarcinoma upregulated factor PMID 33731895
Resolvin E1 Inhibits Corneal Allograft Rejection in High
Skp2 is associated with paclitaxel resistance in prostate cancer cells PMID 27175797
PF
Calcipotriol and betamethasone dipropionate exert additive inhibitory effects on the cytokine expression of inflammatory dendritic cell
TM4 cells
KX 02
MID1 Human Pre
ALX 5407 a potent, selective inhibitor of the hGlyT1 glycine transporter PMID 11723250
Sema4c Mouse Pre
Hernandezine Regulates Proliferation and Autophagy
UBB Human Pre
CREB3 suppresses hepatocellular carcinoma progression by depressing AKT signaling through competitively binding with insulin receptor and transcriptionally activating RNA
Terfenadine N
PD
2
Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors PMID 28279847
Interferon
IL
Talarozole, a selective inhibitor of P450
IPrAgCl 873297
caffeoyl ester
IL
Vinculin 抗体 (YA5481)（Vinculin Antibody (YA5481)）
CALCOCO1 Human Pre
C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross
Hodgkin lymphoma A 2020 update on diagnosis, risk
Identification of PRMT5 as a therapeutic target in cholangiocarcinoma PMID 39266051
Ninety
AZD1208 1204144
Histone deacetylase inhibitors differentially stabilize acetylated p53 and induce cell cycle arrest or apoptosis in prostate cancer cells PMID 15746940
Myrothecine A modulates the proliferation of HCC cells and the maturation of dendritic cells through downregulating miR
Optimization of potent, broad
The tyrosine kinase inhibitor tyrphostin AG 126 reduces the multiple organ failure induced by zymosan in the rat PMID 12107686
ROS
Chinese herbal medicinal ingredients inhibit secretion of IL
Favipiravir (T
D
Adipor1
Histone deacetylase 3 as a novel therapeutic target in multiple myeloma PMID 23913134
Cytogenetic effects of Jacareubin from Calophyllum brasiliense on human peripheral blood mononucleated cells in vitro and on mouse polychromatic erythrocytes in vivo PMID 28943391
Biotin
Isomorellinol 149655
SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway PMID 23017388
Mechanism of biotin carboxylase inhibition by ethyl 4
Scutellarin protects the kidney from ischemia/reperfusion injury by targeting Nrf2 PMID 35638402
ALV 1
Galangin 3
Enantioselective Phytotoxicity of Imazamox Against Maize Seedlings PMID 26508428
Linking High
PCC0208009, an indirect IDO1 inhibitor, alleviates neuropathic pain and co
PF
KUS121, a VCP modulator, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress PMID 28317920
Light
Vascular Cell Adhesion Molecule
NKG2A 蛋白, Human (HEK293, His)
Alzheimer
Discovery of novel 2,4
Development of CDX
GK444
Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor Translational Studies PMID 30136756
N
9
SFR1 Human Pre
Design and synthesis of adamantyl
Cblc Rat Pre
CD46 蛋白, Cynomolgus (HEK293, His)
Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death PMID 25965523
A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts PMID 24971740
Docosahexaenoic acid reverses PD
Discovery and Structure
Identification of 4
Regulation of inflammatory cytokines and activation of PI3K/Akt pathway by Yiqi Jiedu Formula in recurrent Herpes Simplex Keratitis Experimental and network pharmacology evidence PMID 40120648
Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD PMID 37400851
6
Binding of Sudan II and Sudan IV to bovine serum albumin comparison studies PMID 21951948
Effect of IL
Cxcl11 Rat Pre
Irf4
hCAIX/XII
Long
Para
WAC Human Pre
ARN25657
NPN12830
Benzyl
Cdc23 Rat Pre
LM
Rps14
XCL2 Human Pre
Nelociguat
6
ALDH2 modulator 1 1629615
metabolic stabilities
Rnf4 Rat Pre
MCE
Azido
n
Ketotifen
Meclizine N
Preclinical Evaluation of AMG 337, a Highly Selective Small Molecule MET Inhibitor, in Hepatocellular Carcinoma PMID 27196749
AY31906
ZNF598 Human Pre
Efficacy and Safety of the Anti
CXCR7 modulator 1
Trpm3 Rat Pre
Targeting exhausted cytotoxic T cells through CTLA
Krt14 Rat Pre
Mechanical Compression Regulates Brain Cancer Cell Migration Through MEK1/Erk1 Pathway Activation and GDF15 Expression PMID 31612114
Regulation of globin gene expression in human K562 cells by recombinant activin A PMID 1732015
DK419 2102672
Azido
N
Blinin 125675
R42470
HDAC
Jacaric acid, a linolenic acid isomer with a conjugated triene system, has a strong antitumor effect in vitro and in vivo PMID 22521763
CTNNA1
NOTO Human Pre
CARP
EXOSC2 Human Pre
AF
ELQ 596
N6
STH
TNFAIP3 Human Pre
SAE
MMV1557817 2065197
Tollip Mouse Pre
human islet
Albendazole oxide
PTPN23 Human Pre
Rnf20 Rat Pre
CLR01 sodium 1338489
GNKG 168
SHANK3 Human Pre
GTPαS 71376
LY303511
10S,13aR
Tetramethylfluthrin
Antiplasmodial β
ACu 1
BRD9185
proteome
HO
GSK
SFRP1 蛋白, Human (HEK293, His)
PEG10
AMER3 Human Pre
mmu
mmu
Azido
Nesiritide 124584
CMX
Xrn2 Rat Pre
Isoliquiritigenin inhibits apoptosis and ameliorates oxidative stress in rheumatoid arthritis chondrocytes through the Nrf2/HO
mmu
Capsiamide
Haloperidol (Standard)
The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2 PMID 37819755
ATTO 665 1210944
TRAP
BO 264
D
Gingerenone A Sensitizes the Insulin Receptor and Increases Glucose Uptake by Inhibiting the Activity of p70 S6 Kinase PMID 30296358
Myxobacteria versus sponge
MYPOP Human Pre
PCK2 maintains intestinal homeostasis and prevents colitis by protecting antibody
Characterization of Protease
KT474
NSC216666
NBD
Alkaloids from Cynanchum komarovii with inhibitory activity against the tobacco mosaic virus PMID 11738420
Novel staurosporine
Enc1 Rat Pre
5
2',5'
TRK
3,6
MACIR Human Pre
FAD (Standard)
Pentagalloylglucose reduces AGE
Nfe2
mmu
LNX2 Human Pre
DTX3L Human Pre
FPL 13592
KLHDC7B Human Pre
Molecular basis of CX
UMK 57
Telmesteine 122946
Triptolide
VPS50 Human Pre
L
UMK57 342595
Cul4a Rat Pre
Dnajc11 Rat Pre
mmu
TRK
MTHFD1/2
Azido
Six5 Rat Pre
Pank3 Rat Pre
ITPKB Human Pre
DDX46 Human Pre
(R)
Trametinib
mmu
Paliperidone impurity12
Cadherin
PRDM14 Human Pre
TNFSF4
PFKFB4 Human Pre
Zfp36 Rat Pre
SCO
Bazedoxifene hydrochloride 198480
BMS 184476
BMS 181176
G2
Molnupiravir
GSTO1
YT
EIDD
2
Lynestrenol a progesteronelike agent with immunostimulatory properties PMID 6972071
IITR 08367
Acecarbromal
human P2X1
Cdc7
Linagliptin
Sancycline hydrochloride 6625
SPATA13 Human Pre
hsa
MCE
Donepezil impurity4
Paeoniflorigenone
B4GAT1
Synthesis and biological evaluation of thiazolidine
Modafinil acid sulfone
MDM2
Staurosporine Derivatives Generated by Pathway Engineering in a Heterologous Host and Their Cytotoxic Selectivity PMID 30106291
SPEN
BIBW 22 137694
R50595
Novel diaryl
Determination of a PDE4 inhibitor Hemay005 in human plasma and urine by UPLC
LUF6096 1116652
20(R)
Resveratrol rescued the pain related hypersensitivity for Cntnap2
Cordyceps militaris Immunomodulatory Protein Promotes the Phagocytic Ability of Macrophages through the TLR4
Dolutegravir
MBP Ac1
Histone H3K9 Lactylation Confers Temozolomide Resistance in Glioblastoma via LUC7L2
GK444 3032392
UP 163
TER 117
PI4 kinases
Dolutegravir
FIKK
BMS
Ugaxanthone 13179
EBL
regresses
RMC4550
FOXR1 Human Pre
Discovery and biological profile of 4
RIP3 induces apoptosis independent of pronecrotic kinase activity PMID 25459880
LENG8 Human Pre
biloba
LDOC1 Human Pre
U251
Otviciclib 2228039
Hydrophilic nanofibers with aligned topography modulate macrophage
Agrimol B
IL
Lupenone
DL
JHU
BW
NBD
Fads2 Rat Pre
PCSK9 function and physiology PMID 18375913
Ocifisertib 1338806
ALR2
TCMCB07 1456699
hWPA
keratin
XJB
Vitamin C Promotes Muscle Development Mediated by the Interaction of CSRP3 with MyoD and MyoG PMID 35652451
Bibapcitide
Futibatinib
Cyclokievitone (环维酮)
Safety and efficacy of quavonlimab, a novel anti
Dmrt3
Misp
Aripiprazole impurity 30
Ac
(R)
PD81723 132861
root galling
PDGFR
Benzenedimethanamine
MCE
Bromo
CATPB
KWCN
Antitumor agent
New tacrine
Antitumor agent
MurA
Trichlormethiazide sodium 91996
Dehydroacerogenin C
Nivimedone (BRL 10833 free base)
Gfap
L
Mid1
Rasd1
5(6)
The effect of G
GB
β
Lgals9
Methyltetrazine
SGC
WCK
Polygalacic acid 22338
Identification of clinical isolates of indole
Anticancer agent 43 2470015
3
Yp537 166664
Ascl1
Ensa
Chrysin
Slow but Steady Wins the Race Dissimilarities among New Dual Inhibitors of the Wild
High PRMT5 levels, maintained by KEAP1 inhibition, drive chemoresistance in high
Polycyclic aromatic hydrocarbon aggravates high
S
Cinnamyl isovalerate
Agrobacterium vitis
hCAI/II/XII
Selective growth inhibition of a human malignant melanoma cell line by sesame oil in vitro PMID 1502251
The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil PMID 11890515
Phlorofucofuroeckol A (根富鹅掌菜酚A)
Ginsenoside Rg1 protects cardiac mitochondrial function via targeting GSTP1 to block S
4′,5′
Role of RPTPβ/ζ in neuroinflammation and microglia
Mal
Targeting Runt
Importance of imidazoline receptors in the cardiovascular actions of centrally acting antihypertensive agents PMID 7677371
Vedaprofen 71109
IFITM10 Enhance Tumor Angiogenesis and Promotes Cancer Progression through STAT3 Activation PMID 39206889
Lonicerin, an anti
Selenazofurin
The crosstalk between LINC01089 and hippo pathway inhibits osteosarcoma progression PMID 36399257
7570
N
Natural quinazolinones From a treasure house to promising anticancer leads PMID 36375335
DBCO
Synthesis and initial evaluation of YM
Acetyl
Sitakisogenin
RNF43 蛋白, Canine (HEK293, His)
Murrayamine C 134779
NS8593 875755
3′
Regulating mitochondrial homeostasis and inhibiting inflammatory responses through Celastrol PMID 35530963
Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro PMID 23415114
Curindolizine
Combined TRPC3 and TRPC6 blockade by selective small
Quinone
Synthesis, biological and molecular docking studies of pyrimidine
boronic
Discovery of Kasugamycin as a Potent Inhibitor of Glycoside Hydrolase Family 18 Chitinases PMID 33898519
Design and Synthesis of Novel Celastrol Derivatives as Potential Anticancer Agents against Gastric Cancer Cells PMID 35536757
Nafcillin sodium 985
FFA3 agonist 1 886358
chromosomal aberrations
Stearoyl
Exploring unsymmetrical dyads as efficient inhibitors against the insect β
Role of irisin in physiology and pathology PMID 36225200
Erlotinib Hydrochloride 183319
Chondroitinase ABC Administration Facilitates Serotonergic Innervation of Motoneurons in Rats With Complete Spinal Cord Transection PMID 35845919
Surfactin C2
Trans
Benmoxin 7654
Ro 31
APX005M, a CD40 agonist antibody with unique epitope specificity and Fc receptor binding profile for optimal therapeutic application PMID 33392713
Thrombostatin, a bradykinin metabolite, reduces platelet activation in a model of arterial wall injury PMID 11922908
Upregulation of P2X7 Exacerbates Myocardial Ischemia
Topoisomerase poisoning by the flavonoid nevadensin triggers DNA damage and apoptosis in human colon carcinoma HT29 cells PMID 34635930
Identification and preliminary structure
Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3
THO Complex
cGMP a unique 2nd messenger molecule
Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T
Anti
RGLS4326 sodium scrambled negative control
In Silico Discovery of a Small Molecule Suppressing Lung Carcinoma A549 Cells Proliferation and Inducing Autophagy via mTOR Pathway Inhibition PMID 30346178
NECTIN1 Human Pre
Histone H3K27 acetylation mediated by KAT8 maintains antiviral trained immunity in shrimp induced by inactivated white spot syndrome virus PMID 40885857
spasm
SCD5 Human Pre
Lidocaine Ameliorates Psoriasis by Obstructing Pathogenic CGRP Signaling‒Mediated Sensory Neuron‒Dendritic Cell Communication PMID 35032503
AV006
Entpd1
JNJ
Revealing a new target Celastrol alleviates pulmonary fibrosis by inhibiting PCAF PMID 40616946
Tryptophan
Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes PMID 30151596
A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity PMID 591813
Antifungal amides from Piper scutifolium and Piper hoffmanseggianum PMID 18031016
Piptocarphin F 76215
Dysregulation of interaction between LOXhigh fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection PMID 34976220
CRISPR screen of venetoclax response
The KIT and PDGFRA switch
Pharmacologic profile of lipoxins A5 and B5 new biologically active eicosanoids PMID 2545463
Baclofen
Imidocarb 27885
(2E)
SH3YL1 Human Pre
Nerigliatin 1245603
TER117
Antischistosomal Properties of Hederacolchiside A1 Isolated from Pulsatilla chinensis PMID 29899232
EDHS
PHPS1 314291
C26 D,L
Kaempferol protects against propacetamol
Baclofen, a GABAB receptor agonist, enhances ubiquitin
Sudemycin E 1197054
Anti
TIE
Ligand
Anti
Long non
Chronic stress induces wide
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